McGuffin, P, Asherson, P, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and Farmer, A 1994. The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? British Journal of Psychiatry 164 (5) , pp. 593-599. 10.1192/bjp.164.5.593 |
Official URL: http://bjp.rcpsych.org/content/164/5/593.long
Abstract
The evidence for a genetic contribution to schizophrenia is compelling. However, the pattern of inheritance is complex and it is usually assumed that environmental factors also have a role that will eventually be identified. We argue that this is not necessarily the case. While a hypothesis combining genetic diathesis with environmental stress cannot be disproved, it is also possible that 'non-genetic' factors consist entirely of stochastic events affecting gene expression or structure.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine Neuroscience and Mental Health Research Institute (NMHRI) |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | Royal College of Psychiatrists |
ISSN: | 0007-1250 |
Last Modified: | 31 Oct 2022 09:18 |
URI: | https://orca.cardiff.ac.uk/id/eprint/80550 |
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