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No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

Owen, Michael John, Mant, R., Parfitt, E., Williams, Julie, Asherson, P., O'Mahoney, G., Van Os, J., Llewellyn, D., Collier, D., Gill, M. and McGuffin, P. 1992. No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia. Human Genetics 90 (1-2) , pp. 131-132. 10.1007/BF00210756

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Abstract

An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Publisher: Springer
ISSN: 0340-6717
Last Modified: 04 Jun 2017 08:36
URI: http://orca.cf.ac.uk/id/eprint/80874

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