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Modelling the occurrence and pathology of Alzheimer's disease

Hardy, J.A., Goate, A.M., Owen, Michael John, Mullan, M.J., Rossor, M.N. and Pearson, R.C.A. 1989. Modelling the occurrence and pathology of Alzheimer's disease. Neurobiology of Aging 10 (5) , pp. 429-431. 10.1016/0197-4580(89)90084-5

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Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Publisher: Elsevier
ISSN: 0197-4580
Last Modified: 04 Jun 2017 08:36

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