Owen, Michael John, Williams, Nigel Melville and O'Donovan, Michael Conlon 2004. Dysbindin-1 and schizophrenia: from genetics to neuropathology. The Journal of Clinical Investigation 113 (9) , pp. 1255-1257. 10.1172/JCI200421470 |
Official URL: http://dx.doi.org/10.1172/JCI21470
Abstract
The gene encoding dysbindin-1 has recently been implicated in susceptibility to schizophrenia. In this issue of the JCI, Talbot et al. show that, contrary to expectations, dysbindin-1 is located presynaptically in glutamatergic neurons and is reduced at these locations in schizophrenia. Further studies of dysbindin-1 and the proteins with which it interacts can be expected to throw light on the pathogenesis of schizophrenia.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine Neuroscience and Mental Health Research Institute (NMHRI) |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | American Society for Clinical Investigation |
ISSN: | 0021-9738 |
Last Modified: | 24 Jan 2018 21:32 |
URI: | http://orca.cf.ac.uk/id/eprint/81686 |
Actions (repository staff only)
![]() |
Edit Item |