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Association between CCL2 haplotypes and knee osteoarthritis

Hulin-Curtis, Sarah, Bidwell, J. L. and Perry, M. J. 2013. Association between CCL2 haplotypes and knee osteoarthritis. International Journal of Immunogenetics 40 (4) , pp. 280-283. 10.1111/iji.12015

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Abstract

We examined five single nucleotide polymorphisms (SNPs) and reconstructed 5-locus haplotypes of the CCL2 gene, in knee osteoarthritis (OA) cases and in controls. The CCL2 rs2857657 variant (G) allele was observed more frequently in female knee OA cases than in controls. One haplotype (H5) was observed exclusively in the control group (f = 2.3%). Genetic variation in the CCL2 gene may be associated with knee OA.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: Wiley-Blackwell
ISSN: 1744-3121
Date of Acceptance: 2013
Last Modified: 04 Jun 2017 08:43
URI: http://orca.cf.ac.uk/id/eprint/83729

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