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Tumour necrosis factor receptor superfamily member 11B polymorphisms and association with knee osteoarthritis in women

Hulin-Curtis, Sarah, Bidwell, J. L. and Perry, M. J. 2012. Tumour necrosis factor receptor superfamily member 11B polymorphisms and association with knee osteoarthritis in women. International Journal of Immunogenetics 39 (3) , pp. 207-209. 10.1111/j.1744-313X.2012.01083.x

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Abstract

We examined single-nucleotide polymorphisms (SNPs) across the tumour necrosis factor receptor superfamily member 11B (TNFRSF11B) gene and knee OA. We identified alleles in a VNTR region in intron 3 that was observed exclusively in women OA cases (P = 0.007, Pc = 0.042). Our results reveal that a previously unreported association between a VNTR genotype in TNFRSF11B and knee OA in women.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Wiley-Blackwell
Date of Acceptance: 19 December 2011
Last Modified: 04 Jun 2017 08:43
URI: http://orca.cf.ac.uk/id/eprint/83736

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