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Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data

Basra, M.K.A., Salek, M.S., Camilleri, L., Sturkey, R. and Finlay, Andrew Yule 2015. Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data. Dermatology 230 (1) , pp. 27-33. 10.1159/000365390

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Abstract

Aims: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases. Methods: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI. Results: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a ‘small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID. Conclusions: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RL Dermatology
Uncontrolled Keywords: DLQI, MCID, Responsiveness, Minimum clinically important difference, Skin disease
Publisher: Karger
ISSN: 1018-8665
Date of Acceptance: 19 June 2014
Last Modified: 11 Jun 2019 09:07
URI: http://orca.cf.ac.uk/id/eprint/84592

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