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Gold finger formation studied by high-resolution mass spectrometry and in silico methods

Laskay, Ü. A., Garino, C., Tsybin, Y. O., Salassa, L. and Casini, Angela ORCID: https://orcid.org/0000-0003-1599-9542 2015. Gold finger formation studied by high-resolution mass spectrometry and in silico methods. Chemical Communications 51 (9) , pp. 1612-1615. 10.1039/C4CC07490D

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Abstract

High-resolution mass spectrometry and quantum mechanics/molecular mechanics studies were employed for characterizing the formation of two gold finger (GF) domains from the reaction of zinc fingers (ZF) with gold complexes. The influence of both the gold oxidation state and the ZF coordination sphere in GF formation provided useful insights into the possible design of new gold complexes targeting specific ZF motifs.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: RSC Publishing
ISSN: 1359-7345
Date of Acceptance: 2 December 2014
Last Modified: 31 Oct 2022 10:27
URI: https://orca.cardiff.ac.uk/id/eprint/84943

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