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Motor and perceptual timing in Parkinson's Disease

Jones, Catherine C. R. and Jahanshahi, Marjan 2014. Motor and perceptual timing in Parkinson's Disease. In: Merchant, Hugo and De Lafuente, Victor eds. Neurobiology of Interval Timing, Vol. 829. Advances in Experimental Medicine and Biology, Springer, pp. 265-290. (10.1007/978-1-4939-1782-2_14)

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Abstract

Neuroimaging has been a powerful tool for understanding the neural architecture of interval timing. However, identifying the critical brain regions engaged in timing was initially driven by investigation of human patients and animals. This chapter draws on the important contribution that the study of patients with Parkinson’s disease (PD) has made in identifying the basal ganglia as a key component of motor and perceptual timing. The chapter initially describes the experimental tasks that have been critical in PD (and non-PD) timing research before systematically discussing the results from behavioural studies. This is followed by a critique of neuroimaging studies that have given insight into the pattern of neural activity during motor and perceptual timing in PD. Finally, discussion of the effects of medical and surgical treatment on timing in PD enables further evaluation of the role of dopamine in interval timing.

Item Type: Book Section
Date Type: Publication
Status: Published
Schools: Psychology
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: Springer
ISSN: 00652598
Last Modified: 04 Jun 2017 08:50
URI: http://orca.cf.ac.uk/id/eprint/85920

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