Harrison, Judith ORCID: https://orcid.org/0000-0002-5775-2524 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2016. Alzheimer's disease: the amyloid hypothesis on trial. British Journal of Psychiatry 208 (1) , pp. 1-3. 10.1192/bjp.bp.115.167569 |
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Official URL: http://dx.doi.org/10.1192/bjp.bp.115.167569
Abstract
The pathogenesis of Alzheimer's disease is complex. The amyloid hypothesis has directed research efforts for many years, but it has recently been questioned after failed drug trials. Here, we review the evidence for and against and suggest that it might be premature to abandon the amyloid hypothesis.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine Neuroscience and Mental Health Research Institute (NMHRI) |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | Royal College of Psychiatrists |
ISSN: | 0007-1250 |
Date of First Compliant Deposit: | 10 October 2018 |
Date of Acceptance: | 21 July 2015 |
Last Modified: | 18 Nov 2024 02:15 |
URI: | https://orca.cardiff.ac.uk/id/eprint/87545 |
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