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Epilepsy prevalence, incidence and socioeconomic deprivation [Conference Abstract]

Pickrell, Owen, Lacey, Arron, Bodger, Owen, Demmler, Joanne, Thomas, Rhys Huw, Lyons, Ronan, Smith, Phil, Rees, Mark and Kerr, Michael Patrick 2014. Epilepsy prevalence, incidence and socioeconomic deprivation [Conference Abstract]. Journal of Neurology, Neurosurgery & Psychiatry 85 (10) , e4.150. 10.1136/jnnp-2014-309236.4

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Abstract

Aims To investigate the relationship between socioeconomic deprivation, epilepsy prevalence and incidence. Method: We reviewed electronic primary health care records in Wales from 2004 to 2010 identifying prevalent and incident cases of epilepsy and recording linked deprivation scores. Logistic and Poisson regression models were used to calculate odds ratios and incidence rate ratios. The change in deprivation was measured ten years after the initial diagnosis of epilepsy for a cohort of people. Results 8.1 million patient years of records were reviewed. Epilepsy prevalence and incidence were significantly associated with deprivation. Prevalence ranged from 1.12% (1.07%–1.19%) in the most deprived decile to 0.49% (0.45%–0.53%) in the least deprived decile (adjusted odds ratio 0.92 p<0.001). Incidence ranged from 40/100000/year in the most deprived decile to 19/100000/year in the least deprived decile (adjusted incidence rate ratio 0.94 p<0.001). There was no significant change in deprivation index decile nine years after a new diagnosis of epilepsy (mean difference=-0.04, p=0.999). Conclusion Epilepsy prevalence is strongly associated with socioeconomic deprivation. Post-diagnosis ‘social drift’ is a less likely explanation for this relationship given that incidence is also associated with deprivation and deprivation score does not change ten years after diagnosis.

Item Type: Article
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: BMJ Publishing Group
ISSN: 0022-3050
Last Modified: 26 Nov 2017 03:02
URI: http://orca.cf.ac.uk/id/eprint/88690

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