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Nutraceutical therapies for atherosclerosis

Moss, Joe W. E. and Ramji, Dipak P. 2016. Nutraceutical therapies for atherosclerosis. Nature Reviews Cardiology 13 (9) , pp. 513-532. 10.1038/nrcardio.2016.103

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Abstract

Atherosclerosis is a chronic inflammatory disease affecting large and medium arteries and is considered to be a major underlying cause of cardiovascular disease (CVD). Although the development of pharmacotherapies to treat CVD has contributed to a decline in cardiac mortality in the past few decades, CVD is estimated to be the cause of one-third of deaths globally. Nutraceuticals are natural nutritional compounds that are beneficial for the prevention or treatment of disease and, therefore, are a possible therapeutic avenue for the treatment of atherosclerosis. The purpose of this Review is to highlight potential nutraceuticals for use as antiatherogenic therapies with evidence from in vitro and in vivo studies. Furthermore, the current evidence from observational and randomized clinical studies into the role of nutraceuticals in preventing atherosclerosis in humans will also be discussed.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Nature Publishing Group
ISSN: 1759-5002
Funders: British Heart Foundation
Date of First Compliant Deposit: 31 August 2016
Last Modified: 10 Jul 2019 09:02
URI: http://orca.cf.ac.uk/id/eprint/92413

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