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Azobenzene photocontrol of peptides and proteins

Mart, Robert and Allemann, Rudolf 2016. Azobenzene photocontrol of peptides and proteins. Chemical Communications 52 (83) , pp. 12262-12277. 10.1039/C6CC04004G

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Abstract

The last few years have witnessed significant advances in the use of light as a stimulus to control biomolecular interactions. Great efforts have been devoted to the development of genetically encoded optobiological and small photochromic switches. Newly discovered small molecules now allow researchers to build molecular systems that are sensitive to a wider range of wavelengths of light than ever before with improved switching fidelities and increased lifetimes of the photoactivated states. Because these molecules are relatively small and adopt predictable conformations they are well suited as tools to interrogate cellular function in a spatially and temporally contolled fashion and for applications in photopharmacology.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Funders: BBSRC, EPSRC, Royal Society
Date of First Compliant Deposit: 3 October 2016
Date of Acceptance: 1 August 2016
Last Modified: 11 Dec 2018 16:37
URI: http://orca.cf.ac.uk/id/eprint/95052

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