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Intra-articular injections for osteoarthritis: from bench to bedside, can we teach old drugs new tricks?

Lee, Paul Yuh Fang and Brock, James 2016. Intra-articular injections for osteoarthritis: from bench to bedside, can we teach old drugs new tricks? Journal of Arthritis 5 (3) , 1000e111. 10.4172/2167-7921.1000e111

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Abstract

The two articles in this month’s press of e Journal of Arthritis, one by Ekinci et al. titled ‘A New Treatment Option in Osteoarthritis: Prolotherapy Injections’ and the other by Senatorov et al. titled ‘Clinical Outcome of Hylan G-F 20 Injections in Shoulder and Hip Osteoarthritis: A Retrospective Review’ raise several important points surrounding the topic of intra-articular injections [1,2]. Firstly that there is a paucity of high quality literature in the eld that o en leads to inconclusive or misrepresented conclusions on drug e cacy in established treatments [1,2]. e articles also highlight the heterogeneity in injection procedure, site, concentration, preparation and outcome measurements [1,2]. is editorial will, therefore, provide a concise review on some of the current injection therapies and suggest possible improvements to methodological structure to inspire readers strive for high quality data. Further, through an example of a possible novel therapy, Actovegin, this editorial will hopefully challenge readers’ way of thinking to consider the reapplication of established drugs; posing the question can you teach an old drug new tricks?

Item Type: Article
Date Type: Publication
Status: Published
Schools: Engineering
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: Osteoarthritis; Prolotherapy; Injections; Actovegin;Steroid; HA
Publisher: Omics Publisher Group
ISSN: 2167-7921
Date of First Compliant Deposit: 9 December 2016
Date of Acceptance: 29 June 2016
Last Modified: 25 May 2019 22:38
URI: http://orca.cf.ac.uk/id/eprint/96371

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