Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery

Hill, Stephen A., Benito-Alifonso, David., Morgan, David John ORCID: https://orcid.org/0000-0002-6571-5731, Davis, Sean A., Berry, Monica and Galan, M. Carmen 2016. Three-minute synthesis of sp3 nanocrystalline carbon dots as non-toxic fluorescent platforms for intracellular delivery. Nanoscale 8 (44) , pp. 18630-18634. 10.1039/C6NR07336K

[thumbnail of c6nr07336k.pdf]
Preview
PDF - Published Version
Available under License Creative Commons Attribution.

Download (1MB) | Preview

Abstract

A one-pot, three-minute, gram-scale synthesis of novel sp3-nanocrystalline, water-soluble, and fluorescent carbon dots (FCDs), from simple and cheap sugar starting materials is described. Mechanism studies showed that NH2-FCD formation proceeds via a crucial imine intermediate derived from reaction between a sugar hemiacetal and an amine. Moreover, we successfully demonstrate the utility of lactose functionalized FCDots (Lac-FCDots) as non-toxic fluorescent intracellular delivery vehicles.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Cardiff Catalysis Institute (CCI)
Chemistry
Subjects: Q Science > QD Chemistry
Publisher: RSC Publishing
ISSN: 2040-3364
Funders: EPSRC
Date of First Compliant Deposit: 1 December 2016
Date of Acceptance: 20 October 2016
Last Modified: 05 May 2023 18:23
URI: https://orca.cardiff.ac.uk/id/eprint/96551

Citation Data

Cited 43 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics