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Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening

Czodrowski, Paul, Mallinger, Aurélie, Wienke, Dirk, Esdar, Christina, Pöschke, Oliver, Busch, Michael, Rohdich, Felix, Eccles, Suzanne A., Ortiz-Ruiz, Maria-Jesus, Schneider, Richard, Raynaud, Florence I., Clarke, Paul A., Musil, Djordje, Schwarz, Daniel, Dale, Trevor Clive, Urbahns, Klaus, Blagg, Julian and Schiemann, Kai 2016. Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening. Journal of Medicinal Chemistry 59 (20) , pp. 9337-9349. 10.1021/acs.jmedchem.6b00597

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Item Type: Article
Date Type: Published Online
Status: Published
Schools: Biosciences
ISSN: 0022-2623
Date of First Compliant Deposit: 9 December 2016
Date of Acceptance: 4 August 2016
Last Modified: 04 Jun 2017 09:33
URI: http://orca.cf.ac.uk/id/eprint/96681

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Cited 28 times in Scopus. View in Scopus. Powered By Scopus® Data

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