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Development and validation of characterization methods for Lipidots® Multifunctional Platform: a step towards industrial transfer

Varache, Mathieu, Ciancone, M, Caputo, F, Laffont, C, Escudé, M, Jary, D, Boisseau, P, Texier, I, Navarro, F and Couffin, A-C 2016. Development and validation of characterization methods for Lipidots® Multifunctional Platform: a step towards industrial transfer. Presented at: 19th Annual Nanotech Conference and Expo, Washington, 22 May 2016 through 25 May 2016.

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Abstract

Lipidots® technology has thrived towards a versatile nanodelivery platform for designing and producing a series of nanoproducts for in vivo diagnostic, in vivo imaging, activated or non-activated targeted drug delivery. In order to ensure quality of final products, characterization as nanotherapeutics is a key parameter. Thus, we are seeking to implement and validate a panel of characterization methods significantly suitable for Lipidots®. More particularly, we have investigated the lipid quantification, the drug/dye encapsulation, release kinetics and leakage to anticipate the nanocarrier behavior in biological media.

Item Type: Conference or Workshop Item (Paper)
Status: Unpublished
Schools: Dentistry
Subjects: R Medicine > RK Dentistry
Uncontrolled Keywords: lipid nanocarriers, nanomedicine, physical-chemical characterizations, analytical chemistry
Date of First Compliant Deposit: 30 January 2017
Date of Acceptance: 1 March 2016
Last Modified: 04 Jun 2017 09:39
URI: http://orca.cf.ac.uk/id/eprint/97875

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