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Safe and Efficient Ritter Reactions in Flow

Brandt, Johan Christian, Elmore, Simon C., Robinson, Richard I. and Wirth, Thomas 2010. Safe and Efficient Ritter Reactions in Flow. Synlett (20) , pp. 3099-3103. 10.1055/s-0030-1259075

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Abstract

Efficient mixing, temperature control and small environmental exposures allow reactions carried out in microfluidic de vices to perform superior to their batch-type counterparts in conventional flasks. The Ritter reaction has been optimised for flow conditions leading to short reaction times and higher yields and also is more feasible with regards to safety, productivity and tolerance towards substrate functionalities.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: amide - carbocation - microreactor - Ritter Reaction - safety
Publisher: Georg Thieme Verlag
ISSN: 0936-5214
Last Modified: 04 Jun 2017 02:08
URI: http://orca.cf.ac.uk/id/eprint/9800

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