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Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity

Jones, Jennifer Elizabeth, Amoroso, Angelo James, Dorin, Irina Mihaela, Parigi, Giacomo, Ward, Benjamin David, Buurma, Niklaas Jan and Pope, Simon J. A. 2011. Bimodal, dimetallic lanthanide complexes that bind to DNA: the nature of binding and its influence on water relaxivity. Chemical Communications 47 (12) , pp. 3374-3376. 10.1039/C1CC00111F

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Abstract

UV-visible titrations, 1H NMRD experiments and molecular docking studies show that emissive anthraquinone appended dimetallic lanthanide complexes bind to DNA. The strength of binding and the observed relaxivity behaviour depend on the nature of the substituted anthraquinone core.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Last Modified: 03 Apr 2018 20:39
URI: http://orca.cf.ac.uk/id/eprint/9834

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