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Update on Neoadjuvant Regimens for Patients with Operable Oesophageal/Gastrooesophageal Junction Adenocarcinomas and Squamous Cell Carcinomas

Cox, Samantha, O?Cathail, Sean M., Coles, Bernadette, Crosby, Tom and Mukherjee, Somnath 2017. Update on Neoadjuvant Regimens for Patients with Operable Oesophageal/Gastrooesophageal Junction Adenocarcinomas and Squamous Cell Carcinomas. Current Oncology Reports 19 (1) , 7. 10.1007/s11912-017-0559-8

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Abstract

Survival outcomes following multimodal treatment of operable oesophageal and gastrooesophageal cancer remain disappointingly poor. Although an appreciation of the impact of both tumour location and histological subtype is now shaping the design of clinical trials, there has been a lack of consensus of the optimal neoadjuvant treatment strategy. This update article will review recent advances in the use of both neoadjuvant chemotherapy and chemoradiotherapy. The emerging role of PET imaging to direct appropriate neoadjuvant treatment regimens and the additive benefit of biological agents are also discussed.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Postgraduate Medical and Dental Education
Uncontrolled Keywords: Neoadjuvant Oesophagus Gastrooesophageal junction Adenocarcinoma Squamous cell carcinoma Chemotherapy Chemoradiotherapy
Publisher: Springer
ISSN: 15233790
Date of First Compliant Deposit: 5 April 2017
Date of Acceptance: 3 January 2017
Last Modified: 31 Jul 2017 08:08
URI: http://orca.cf.ac.uk/id/eprint/99659

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