Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Effects of inhibitors on mitochondrial adenosine triphosphatase of Tetrahymena pyriformis ST

Unitt, M.D. and Lloyd, David ORCID: https://orcid.org/0000-0002-5656-0571 1981. Effects of inhibitors on mitochondrial adenosine triphosphatase of Tetrahymena pyriformis ST. Microbiology 126 (2) , 261--266. 10.1099/00221287-126-2-261

Full text not available from this repository.

Abstract

Mitochondrial adenosine triphosphatase (ATPase) of the ciliate protozoon Tetrahymena pyriformis ST is completely inhibited by antiserum prepared against F1-ATPase purified from Schizosaccharomyces pombe, and by naturally occurring inhibitor proteins from this yeast and from bovine heart mitochondria. An ATPase inhibitor protein is also present in extracts of T. pyriformis. Mitochondrial ATPase of T. pyriformis is only partially inhibited by the F0-ATPase inhibitors N,N'-dicyclohexylcarbodiimide, oligomycin, leucinostatin, triethyltin sulphate and venturicidin, and (at high titres) by the F1-ATPase inhibitors Dio-9, efrapeptin, 4-chloro-7-nitrobenzofurazan and spegazzinine. Aurovertin, citreoviridin and quercetin were not inhibitory. Resistance to inhibitors distinguishes this mitochondrial ATPase from all those previously examined.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Microbiology Society
ISSN: 1350-0872
Date of Acceptance: 6 April 1981
Last Modified: 26 Oct 2022 08:40
URI: https://orca.cardiff.ac.uk/id/eprint/128041

Citation Data

Cited 12 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item