Time-differential PAC parameters for 111In-DTPA labelled vesicles

Hargrave, Peter Charles ORCID: https://orcid.org/0000-0002-3109-6629, Smith, F. A., Bown, K. and Carr, R. 1995. Time-differential PAC parameters for 111In-DTPA labelled vesicles. Chemical Physics Letters 246 (6) , pp. 626-631. 10.1016/0009-2614(95)01157-2

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Abstract

The perturbed angular correlation of γ-rays from labelled phospholipid vesicles has been found to be caused by approximately equal contributions from static and time-dependent effects. A comparison between the PAC parameters from the labelled vesicular system and the labelled DTPA reporter molecule alone suggests that the PAC nuclide is located within, and not on, the bilayer wall. When the vesicles are lysed with triton detergent, there appears to be a reduction in the time-dependent electric quadrupole field gradient seen by the PAC nuclide but not significant reduction in the size of the bilayer fragments.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Physics and Astronomy
Subjects:	Q Science > QB Astronomy
Publisher:	Elsevier
ISSN:	0009-2614
Last Modified:	24 Oct 2022 11:37
URI:	https://orca.cardiff.ac.uk/id/eprint/48729

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