Osborne, C. S., Leitner, I., Hofbauer, B., Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Favre, B. and Ryder, N. S. 2006. Biological, biochemical, and molecular characterization of a new clinical Trichophyton rubrum isolate resistant to terbinafine. Antimicrobial Agents and Chemotherapy 50 (6) , pp. 2234-2236. 10.1128/AAC.01600-05 |
Official URL: http://dx.doi.org/10.1128/AAC.01600-05
Abstract
We have characterized a new clinical strain of Trichophyton rubrum highly resistant to terbinafine but exhibiting normal susceptibility to drugs with other mechanisms of action. Resistance to terbinafine in this strain is caused by a missense mutation in the squalene epoxidase gene leading to the amino acid substitution F397L.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Subjects: | R Medicine > R Medicine (General) |
Publisher: | American Society for Microbiology |
ISSN: | 0066-4804 |
Last Modified: | 28 Oct 2022 08:36 |
URI: | https://orca.cardiff.ac.uk/id/eprint/71415 |
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