Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Templated chromophore assembly by dynamic covalent bonds

Rocard, Lou, Berezin, Andrey, De Leo, Federica and Bonifazi, Davide ORCID: https://orcid.org/0000-0001-5717-0121 2015. Templated chromophore assembly by dynamic covalent bonds. Angewandte Chemie International Edition 54 (52) , pp. 15739-15743. 10.1002/anie.201507186

Full text not available from this repository.

Abstract

Through the simultaneous use of three orthogonal dynamic covalent reactions, namely disulfide, boronate, and acyl hydrazone formation, we conceived a facile and versatile protocol to spatially organize tailored chromophores, which absorb in the blue, red, and yellow regions, on a preprogrammed α-helix peptide. This approach allowed the assembly of the dyes in the desired ratio and spacing, as dictated by both the relative positioning and distribution of the recognition units on the peptide scaffold. Steady-state UV/Vis absorption and emission studies suggest an energy transfer from the yellow and red donors to the blue acceptor. A molecular dynamics simulation supports the experimental findings that the helical structure is maintained after the assembly and the three dyes are confined in defined conformational spaces.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Wiley
ISSN: 1433-7851
Date of Acceptance: 2 August 2015
Last Modified: 06 Jan 2024 04:47
URI: https://orca.cardiff.ac.uk/id/eprint/89061

Citation Data

Cited 36 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item