Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by All Cardiff Authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 213.

Britton, David, Zen, Yoh, Quaglia, Alberto, Selzer, Stefan, Mitra, Vikram, Lößner, Christopher, Jung, Stephan, Böhm, Gitte, Schmid, Peter, Prefot, Petra, Hoehle, Claudia, Koncarevic, Sasa, Gee, Julia Margaret Wendy, Nicholson, Robert, Ward, Malcolm, Castellano, Leandro, Stebbing, Justin, Zucht, Hans Dieter, Sarker, Debashis, Heaton, Nigel and Pike, Ian 2014. Quantification of pancreatic cancer proteome and phosphorylome: Indicates molecular events likely contributing to cancer and activity of drug targets. PLoS ONE 9 (3) , e90948. 10.1371/journal.pone.0090948
file

Jordan, Nicola Jane, Dutkowski, Carol Mary, Barrow, Denise, Mottram, Huw James, Hutcheson, Iain Robert, Nicholson, Robert Ian, Guichard, Sylvie M. and Gee, Julia Margaret Wendy 2014. Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro. Breast Cancer Research 16 (1) , R12. 10.1186/bcr3604
file

McCloy, R. A., Shelley, E. J., Roberts, C. G., Boslem, E., Biden, T. J., Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Sutherland, R. L., Musgrove, E. A., Burgess, A. and Butt, A. J. 2013. Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. British Journal of Cancer 109 (12) , pp. 3034-3041. 10.1038/bjc.2013.693
file

Browne, Brigid C., Hochgräfe, Falko, Wu, Jianmin, Millar, Ewan K. A., Barraclough, Jane, Stone, Andrew, McCloy, Rachael A., Lee, Christine S., Roberts, Caroline, Ali, Naveid A., Boulghourjian, Alice, Schmich, Fabian, Linding, Rune, Farrow, Lynne, Gee, Julia Margaret Wendy, Nicholson, Robert Ian, O'Toole, Sandra A., Sutherland, Robert L., Musgrove, Elizabeth A., Butt, Alison J. and Daly, Roger J. 2013. Global characterization of signalling networks associated with tamoxifen resistance in breast cancer. FEBS Journal 280 (21) , pp. 5237-5257. 10.1111/febs.12441

Lazaro, Glorianne, Smith, Chris, Goddard, Lindy, Jordan, Nicola Jane, McClelland, Richard Andrew, Barrett-Lee, Peter, Nicholson, Robert Ian and Hiscox, Stephen Edward 2013. Targeting focal adhesion kinase in ER+/HER2+ breast cancer improves trastuzumab response. Endocrine Related Cancer 20 (5) , pp. 691-704. 10.1530/ERC-13-0019

Stone, A., Cowley, M. J., Valdes-Mora, F., McCloy, R. A., Sergio, C. M., Gallego-Ortega, D., Caldon, C. E., Ormandy, C. J., Biankin, A. V., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Print, C. G., Clark, S. J. and Musgrove, E. A. 2013. BCL-2 Hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer. Molecular Cancer Therapeutics 12 (9) , pp. 1874-1885. 10.1158/1535-7163.MCT-13-0012

Robertson, John F. R., Dixon, J. Michael, Sibbering, D. Mark, Jahan, Ali, Ellis, Ian O., Channon, Eddie, Hyman-Taylor, Pauline, Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2013. A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer. Breast Cancer Research 15 (2) , R18. 10.1186/bcr3393
file

Kalyuga, Maria, Gallego-Ortega, David, Lee, Heather J., Roden, Daniel L., Cowley, Mark J., Caldon, C. Elizabeth, Stone, Andrew, Allerdice, Stephanie L., Valdes-Mora, Fatima, Launchbury, Rosalind, Statham, Aaron L., Armstrong, Nicola, Alles, M. Chehani, Young, Adelaide, Egger, Andrea, Au, Wendy, Piggin, Catherine L, Evans, Cara J., Ledger, Anita, Brummer, Tilman, Oakes, Samantha R., Kaplan, Warren, Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Sutherland, Robert L., Swarbrick, Alexander, Naylor, Matthew J., Clark, Susan J., Carroll, Jason S. and Ormandy, Christopher J. 2012. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biology 10 (12) , e1001461. 10.1371/journal.pbio.1001461
file

Gangadhara, Sharath, Barrett-Lee, Peter, Nicholson, Robert and Hiscox, Stephen Edward 2012. Pro-metastatic tumor-stroma interactions in breast cancer. Future Oncology 8 (11) , pp. 1427-1442. 10.2217/fon.12.134.

Hiscox, Stephen Edward, Baruha, Bedanta, Smith, Chris, Bellerby, Rebecca, Goddard, Lindy, Jordan, Nicola Jane, Poghosyan, Zaruhi, Nicholson, Robert Ian, Barrett-Lee, Peter and Gee, Julia Margaret Wendy 2012. Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. BMC Cancer 12 , 458. 10.1186/1471-2407-12-458
file

Taylor, Kathryn Mary, Hiscox, Stephen Edward, Nicholson, Robert Ian, Hogstrand, Christer and Kille, Peter 2012. Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7. Science Signaling 5 (210) , ra11. 10.1126/scisignal.2002585
filefile

Kuter, Irene, Gee, Julia Margaret Wendy, Hegg, Roberto, Singer, Christian F., Badwe, Rajendra A., Lowe, Elizabeth S., Emeribe, Ugochi A., Anderson, Elizabeth, Sapunar, Francisco, Finlay, Pauline, Nicholson, Robert Ian, Bines, José and Harbeck, Nadia 2012. Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study. Breast Cancer Research and Treatment 133 (1) , pp. 237-246. 10.1007/s10549-011-1947-7

Caldon, C. Elizabeth, Sergio, C. Marcelo, Kang, Jian, Muthukaruppan, Anita, Boersma, Marikje N., Stone, Andrew, Barraclough, Jane, Lee, Christine S., Black, Michael A., Miller, Lance D., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Sutherland, Robert L., Print, Crispin G. and Musgrove, Elizabeth A. 2012. Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells. Molecular Cancer Therapeutics 11 (7) , pp. 1488-1499. 10.1158/1535-7163.MCT-11-0963

Stone, Andrew, Valdés-Mora, F., Gee, Julia Margaret Wendy, Farrow, Lynne, McClelland, Richard Andrew, Fiegl, H., Dutkowski, Carol Mary, McCloy, R. A., Sutherland, R. L., Musgrove, E. A. and Nicholson, Robert Ian 2012. Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer. PLoS ONE 7 (7) , e40466. 10.1371/journal.pone.0040466
file

White, Alex William, Carpenter, Nicholas, Lottin, Jerome R. P., McClelland, Richard and Nicholson, Robert 2012. Synthesis and evaluation of novel anti-proliferative pyrroloazepinone and indoloazepinone oximes derived from the marine natural product hymenialdisine. European Journal of Medicinal Chemistry 56 , pp. 246-253. 10.1016/j.ejmech.2012.08.022

Hiscox, Stephen Edward, Barrett-Lee, Peter and Nicholson, Robert 2011. Therapeutic targeting of tumor--stroma interactions. Expert Opinion on Therapeutic Targets 15 (5) , pp. 609-621. 10.1517/14728222.2011.561201

Hutcheson, Iain Robert, Goddard, Lindy, Barrow, Denise, McClelland, Richard Andrew, Francies, Hayley E., Knowlden, Janice Mary, Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2011. Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1. Breast Cancer Research 13 (2) , R29. 10.1186/bcr2848
file

Hiscox, Stephen Edward, Barnfather, Peter, Hayes, Edward Raymond, Bramble, Pamela, Christensen, James, Nicholson, Robert Ian and Barrett-Lee, Peter 2011. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Breast Cancer Research and Treatment 125 (3) , pp. 659-669. 10.1007/s10549-010-0857-4

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Barrow, Denise, Robertson, John F., Ellis, Ian O., Nicholson, Robert Ian and Hutcheson, Iain Robert 2011. erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines. Breast Cancer Research 13 (5) , R93. 10.1186/bcr3018
file

Hiscox, Stephen Edward, Barrett-Lee, Peter and Nicholson, Robert Ian 2011. Therapeutic targeting of tumor–stroma interactions. Expert Opinion on Therapeutic Targets 15 (5) , pp. 609-621. 10.1517/14728222.2011.561201

Wadhawan, Anshu, Smith, Chris, Nicholson, Robert Ian, Barrett-Lee, Peter and Hiscox, Stephen Edward 2011. Src-mediated regulation of homotypic cell adhesion: implications for cancer progression and opportunities for therapeutic intervention. Cancer Treatment Reviews 37 (3) , pp. 234-241. 10.1016/j.ctrv.2010.08.003

Gee, Julia Margaret Wendy, Aleskandarany, M., Finlay, Pauline, Farrow, Lynne, Nicholson, Robert Ian, Habashy, H., Green, Adam, Rakha, E., Powell, D., Jasani, Bharat, Barrett-Lee, Peter, Robertson, J., Shaw, Victoria E. and Ellis, Ieuan 2011. Abstract P2-09-37: Immunohistochemical markers progesterone receptor, HER2, Ki67 and bcl-2-Associated Athanogene 1 and prediction of adjuvant Tamoxifen treatment outcome in ER+ early breast cancer [Abstract]. Cancer Research 70 (24 Sup) , P2-09. 10.1158/0008-5472.SABCS10-P2-09-37

Nicholson, Robert Ian, Habashy, H., Gee, Julia Margaret Wendy, Finlay, Pauline, Farrow, Lynne, Jasani, Bharat, Barrett-Lee, Peter, Robertson, J. and Ellis, Ieuan 2011. Abstract P2-06-19: Transferrin Receptor (CD71) identifies poor response to Tamoxifen in oestrogen receptor positive breast cancer patients [Abstract]. Cancer Research 70 (24 Sup) , P2-P6. 10.1158/0008-5472.SABCS10-P2-06-19

Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Barrow, Denise, Dutkowski, Carol Mary, Goddard, Lindy, Jordan, Nicola J., McClelland, Richard Andrew, Knowlden, Janice Mary, Francies, Hayley E., Hiscox, Stephen Edward and Hutcheson, Iain Robert 2011. Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance. Hormone Molecular Biology and Clinical Investigation 5 (2) , pp. 67-77. 10.1515/HMBCI.2011.009

Habashy, Hany O., Powe, Desmond G., Abdel-Fatah, Tarek M., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Green, Andrew R., Rakha, Emad A. and Ellis, Ian O. 2011. A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer. Histopathology 60 (6) , pp. 854-863. 10.1111/j.1365-2559.2011.03912.x

Hayes, Edward Raymond, Nicholson, Robert I. and Hiscox, Stephen Edward 2011. Acquired endocrine resistance in breast cancer: implications for tumour metastasis. Frontiers in Bioscience 16 (1) , pp. 838-848. 10.2741/3723

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Barrow, Denise, Robertson, J. F., Ellis, I. O., Nicholson, Robert Ian and Hutcheson, Iain Robert 2010. O-36 Recruitment of insulin receptor substrate-1 by erbB3 impacts on IGF-IR signalling in oestrogen receptor-positive breast cancer cells [Abstract]. EJC Supplements 8 (6) , pp. 13-14. 10.1016/j.ejcsup.2010.06.037

Davison, Zoe, Nicholson, Robert Ian, Denyer, Stephen Paul and Heard, Charles Martin 2010. A novel diffusion cell model for the 'in vitro' assessment of transcutaneous breast cancer therapeutics: Effect of permeants on MCF-7 cells cultured within the receptor compartment. European Journal Of Pharmaceutics and Biopharmaceutics 75 (3) , pp. 411-417. 10.1016/j.ejpb.2010.03.019

Davison, Zoe, Nicholson, Robert, Denyer, Stephen Paul and Heard, Charles Martin 2010. A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: effect of permeants on MCF-7 cells cultured within the receptor compartment. European Journal of Pharmaceutics and Biopharmaceutics 75 (3) , pp. 411-417. 10.1016/j.ejpb.2010.03.019

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Barrow, Denise, Robertson, J. F., Ellis, I. O., Nicholson, Robert Ian and Hutcheson, Iain Robert 2010. Recruitment of insulin receptor substrate-1 by erbB3 impacts on IGF-IR signalling in oestrogen receptor-positive breast cancer cells [Abstract]. Breast Cancer Research 12 (S1) , S15. 10.1186/bcr2546
file

Hutcheson, Iain Robert, Goddard, Lindy, Gee, Julia Margaret Wendy, Barrow, Denise and Nicholson, Robert Ian 2010. Fulvestrant-induced expression of erbB3 and erbB4 sensitizes ER-positive breast cancer cells to heregulins [Abstract]. Breast Cancer Research 12 (S1) , P13. 10.1186/bcr2510
file

Gutteridge, Eleanor, Agrawal, Amit, Nicholson, Robert Ian, Cheung, Kwok Leung, Robertson, John and Gee, Julia Margaret Wendy 2010. The effects of gefitinib in tamoxifen-resistant and hormone-insensitive breast cancer: a phase II study. International Journal of Cancer 126 (8) , pp. 1806-1816. 10.1002/ijc.24884

Robertson, J. F. R., Dixon, J. M., Sibbering, D. M., Jahan, A., Ellis, I. O., Channon, E., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2010. Biological activity of a combination of fulvestrant 500 mg (F500) plus anastrozole versus F500 alone or anastrozole alone as neoadjuvant treatment for breast cancer [Abstract]. EJC Supplements 8 (3) , p. 63. 10.1016/S1359-6349(10)70050-1

Agrawal, A., Robertson, J. F. R., Gutteridge, E., Cheung, K. L., Ellis, I. O., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2010. 182 Long-term effect of fulvestrant on hormone receptors and proliferation marker in breast cancer [Abstract]. EJC Supplements 8 (3) , p. 111. 10.1016/S1359-6349(10)70213-5

Thomas, Nicholas B. P., Hutcheson, Iain Robert, Campbell, Lee, Gee, Julia Margaret Wendy, Taylor, Kathryn Mary, Nicholson, Robert Ian and Gumbleton, Mark 2010. Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance. Breast Cancer Research and Treatment 119 (3) , pp. 575-591. 10.1007/s10549-009-0355-8

Hiscox, Stephen Edward, Barrett-Lee, Peter, Borley, Annabel Catherine and Nicholson, Robert Ian 2010. Combining Src inhibitors and aromatase inhibitors: A novel strategy for overcoming endocrine resistance and bone loss. European Journal of Cancer 46 (12) , pp. 2187-2195. 10.1016/j.ejca.2010.04.012

Habashy, Hany Onsy, Powe, Desmond G., Staka, Cindy M., Rakha, Emad A., Ball, Graham, Green, Andrew R., Aleskandarany, Mohammed, Paish, E. Claire, Macmillan, R. Douglas, Nicholson, Robert Ian, Ellis, Ian O. and Gee, Julia Margaret Wendy 2010. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Research and Treatment 119 (2) , pp. 283-293. 10.1007/s10549-009-0345-x

Blamey, R. W., Hornmark-Stenstam, B., Ball, G., Blichert-Toft, M., Cataliotti, L., Fourquet, A., Gee, Julia Margaret Wendy, Holli, K., Jakesz, R., Kerin, M., Mansel, Robert Edward, Nicholson, Robert Ian, Pienkowski, T., Pinder, S., Sundquist, M., van de Vijver, M. and Ellis, I. 2010. ONCOPOOL - A European database for 16,944 cases of breast cancer. European Journal of Cancer 46 (1) , pp. 56-71. 10.1016/j.ejca.2009.09.009

Hiscox, Stephen Edward, Barnfather, Peter, Hayes, Edward Raymond, Bramble, P., Christensen, J., Nicholson, Robert Ian and Barrett-Lee, Peter 2009. Inhibition of Focal Adhesion Kinase Suppresses Adverse Features of Endocrine-Resistant Breast Cancer Cells and Improves Endocrine Response in ER plus , Endocrine-Sensitive Cells [Abstract]. Cancer Research 69 (24:S1) , p. 3130. 10.1158/0008-5472.SABCS-09-3130

Robertson, J. F. R., Dixon, J. M., Sibbering, D. M., Jahan, A., Ellis, I. O., Channon, E. J., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2009. Tumor biomarker changes following pre-surgical treatment with 500 mg Fulvestrant plus Anastrozole Versus 500 mg Fulvestrant Alone and 1 mg Anastrozole Alone [Abstract]. Cancer Research 69 (24S) , 491S. 10.1158/0008-5472.SABCS-09-24

Davison, Zoe, Nicholson, Robert Ian, Maillard, Jean-Yves, Denyer, Stephen Paul and Heard, Charles Martin 2009. Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics. Letters in Applied Microbiology 49 (4) , pp. 456-460. 10.1111/j.1472-765X.2009.02685.x

Morgan, Liam David, Gee, Julia Margaret Wendy, Pumford, Sara Louise, Farrow, Lynne, Finlay, Pauline, Robertson, John, Ellis, Ian, Kawakatsu, Hisaaki, Nicholson, Robert Ian and Hiscox, Stephen Edward 2009. Elevated Src kinase activity attenuates tamoxifen response in vitro and is associated with poor prognosis clinically. Cancer Biology and Therapy 8 (16) , pp. 1550-1558. 10.4161/cbt.8.16.8954

Hiscox, Stephen Edward, Jordan, Nicola Jane, Smith, Chris, James, M., Morgan, Liam David, Taylor, Kathryn Mary, Green, T. P. and Nicholson, Robert Ian 2009. Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells. Breast Cancer Research and Treatment 115 (1) , pp. 57-67. 10.1007/s10549-008-0058-6

Kuter, I., Anderson, E., Emeribe, U., Finlay, Pauline, Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2009. Comparison of methods for detection of fulvestrant-induced changes in breast tumor estrogen and progesterone receptor expression in a neoadjuvant trial (NEWEST) [Abstract]. Journal of Clinical Oncology 27 (15S) , e11602.

Baruah, Bedanta Prakash, Smith, Chris, Jordan, Nicola Jane, Nicholson, Robert Ian, Robertson, Jane, Barrett-Lee, Peter and Hiscox, Stephen Edward 2009. Overexpression of CD44 in acquired endocrine resistant breast cancer modulates erbB activity and promotes an invasive phenotype. Cancer Research 69 (2) , 811S-811S.

Baruah, Bedanta Prakash, Barrett-Lee, Peter, Smith, Chris, Nicholson, Robert Ian and Hiscox, Stephen Edward 2009. CD44-Activated HER-2 Signalling in Tamoxifen Resistant Breast Cancer Cells Promotes a Migratory Phenotype. Cancer Research 69 (24) , 811S-811S.

Hiscox, Stephen Edward, Jordan, Nicola Jane, Morgan, Liam David, Smith, Christopher, Goddard, Lindy, Gee, Julia Margaret Wendy and Nicholson, Robert 2009. Adverse features of acquired antihormone resistance and their targeting. In: Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential as Targets, London: Springer, pp. 139-160. (10.1007/978-1-4020-8526-0_8)

Nicholson, Robert Ian, Hutcheson, Iain Robert, Hiscox, Stephen Edward, Taylor, Kathryn Mary and Gee, Julia Margaret Wendy 2009. Experimental endocrine resistance: concepts and strategies. In: Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert Ian eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential, Dordrecht: Springer, pp. 1-26. (10.1007/978-1-4020-8526-0_1)

Elsheikh, S. E., Green, A. R., McClelland, Richard Andrew, Hutcheson, Iain Robert, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Ellis, I. O. 2009. 162 Altered Histone Modifications and their regulating enzymes in Fulvestrant resistant breast cancer cell line In Vitro [Abstract]. Laboratory Investigation 89 (S1) , 38A-39A. 10.1038/labinvest.2008.132

Gee, Julia Margaret Wendy, Stone, Andrew, McClelland, Richard Andrew, Hiscox, Stephen Edward, Hutcheson, Iain Robert, Jordan, Nicola J., Fiegl, Heidi M., Widschwendter, Martin, Shaw, Victoria E., Barrow, Denise and Nicholson, Robert Ian 2009. The dark side of antihormonal action in breast cancer. In: Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert Ian eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential, Dordrecht: Springer, pp. 63-84. (10.1007/978-1-4020-8526-0_4)

Gee, Julia Margaret Wendy, Eloranta, J. J., Ibbitt, J. C., Robertson, J. F. R., Ellis, I. O., Williams, T., Nicholson, Robert Ian and Hurst, H. C. 2009. Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival. The Journal of Pathology 217 (1) , pp. 32-41. 10.1002/path.2430

Shou, J., Osborne, K. C., Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Schiff, R. 2009. Akt-dependent phosphorylation on AIB1 serine 967 contributes to breast cancer tamoxifen resistance [Abstract]. Cancer Research 69 (2) , 211S-211S. 10.1158/0008-5472.SABCS-3021

Hiscox, Stephen Edward, Jordan, Nicola Jane, Crandon-Lewis, A., Jiang, W., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2009. Overexpression of L1CAM accompanies acquired endocrine resistance and is associated with the development of an aggressive cell phenotype [Abstract]. Cancer Research 69 (2) , 213S-213S. 10.1158/0008-5472.SABCS-3028

Davison, Zoe, Nicholson, Robert Ian, Maillard, Jean Yves, Denyer, Stephen Paul and Heard, Christopher Martin 2009. Control of microbial contamination of Franz diffusion cell receptor phase in the development of transcutaneous breast cancer therapeutics. Letters In Applied Microbiology 49 (4) , pp. 456-460. 10.1111/j.1472-765X.2009.02685.x

Hiscox, Stephen Edward and Nicholson, Robert Ian 2009. Resistance to hormone therapy in breast cancer. Advances in Breast Cancer 6 (3) , pp. 2-6.

Kuter, I., Anderson, E., Emeribe, U., Finlay, Pauline, Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2009. Comparison of Methods for Detection of Fulvestrant-Induced Changes in Breast Tumor Estrogen and Progesterone Receptor Expression in a Neoadjuvant Trial (NEWEST). Cancer Research 69 (24) , 566S-567S.

O'Brien, C. S., Howell, S. J., Gee, Julia Margaret Wendy, Lykkesfeldt, A. E., Nicholson, Robert Ian and Clarke, R. B. 2009. Tamoxifen resistance in Estrogen Receptor Positive (ER plus ) breast cancer is driven by Estrogen Receptor Negative (ER-) cancer stem-like cells [Abstract]. Cancer Research 69 (24) , 807S.

Soni, S., Lin, B. T., August, A., Nicholson, Robert Ian and Kirsch, K. H. 2009. Expression of a Phosphorylated p130(Cas) Substrate Domain Attenuates the Phosphatidylinositol 3-Kinase/Akt Survival Pathway in Tamoxifen Resistant Breast Cancer Cells. Journal of Cellular Biochemistry 107 (2) , pp. 364-375. 10.1002/jcb.22136

Wadhawan, Anshu, Barrett-Lee, Peter, Smith, Chris, Nicholson, Robert Ian and Hiscox, Stephen Edward 2009. Src-Dependent Changes in Beta-Catenin Activity Promote a Migratory Phenotype in Endocrine-Resistant Breast Cancer Cells. Cancer Research 69 (24) , 813S.

Hogstrand, C., Kille, Peter, Nicholson, Robert Ian and Taylor, Kathryn Mary 2009. Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation. Trends in Molecular Medicine 15 (3) , pp. 101-111. 10.1016/j.molmed.2009.01.004

Elsheikh, S. E., Green, A. R., McClelland, Richard Andrew, Hutcheson, Iain Robert, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Ellis, I. O. 2009. Altered Histone Modifications and Their Regulating Enzymes in Fulvestrant Resistant Breast Cancer Cell Line In Vitro [Abstract]. Modern Pathology 22 (S1) , 38A-39A. 10.1038/modpathol.2008.210

Law, Jennifer H., Habibi, Golareh, Hu, Kaiji, Masoudi, Hamid, Wang, Michelle. Y. C., Stratford, Anna L., Park, Eugene, Gee, Julia Margaret Wendy, Finlay, Pauline, Jones, Helen E., Nicholson, Robert Ian, Carboni, Joan, Gottardis, Marco, Pollak, Michael and Dunn, Sandra E. 2008. Phosphorylated insulin-like growth factor-I/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Research 68 (24) , pp. 10238-10246. 10.1158/0008-5472.CAN-08-2755

Hurtado, A., Holmes, K. A., Geistlinger, T. R., Hutcheson, Iain Robert, Nicholson, Robert Ian, Brown, M., Jiang, J., Howat, W. J., Ali, S. and Carroll, J. S. 2008. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 456 (7222) , pp. 663-666. 10.1038/nature07483

Hurtado, Antoni, Holmes, Kelly A., Geistlinger, Timothy R., Hutcheson, Iain Robert, Nicholson, Robert Ian, Brown, Myles, Jiang, Jie, Howat, William J., Ali, Simak and Carroll, Jason S. 2008. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen [Letter]. Nature 456 (7222) , pp. 663-666. 10.1038/nature07483

Davison, Zoe, Dutkowski, Carol Mary, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Heard, Charles Martin 2008. In vitro effects on MCF-7 breast cancer cells of signal transduction inhibitor/tamoxifen/eicosapentaenoic acid combinations and their simultaneous delivery across skin. Pharmaceutical Research 25 (11) , pp. 2516-2525. 10.1007/s11095-008-9665-5

Taylor, Kathryn Mary, Vichova, Petra, Jordan, Nicola Jane, Hiscox, Stephen Edward, Hendley, Rhiannon and Nicholson, Robert Ian 2008. ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer cells. Endocrinology 149 (10) , pp. 4912-4920. 10.1210/en.2008-0351

Knowlden, Janice Mary, Jones, Helen E., Barrow, Denise, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Hutcheson, Iain Robert 2008. Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance. Breast Cancer Research and Treatment 111 (1) , pp. 79-91. 10.1007/s10549-007-9763-9

Hiscox, Stephen Edward, Goddard, Lindy, Jordan, Nicola Jane, Smith, Chris, Harper, Maureen Elaine, Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2008. Overexpression of CD44 in acquired tamoxifen-resistant breast cancer cells augments their migratory response to heregulin beta 1 [Abstract]. Breast Cancer Research 10 (S2) , P34. 10.1186/bcr1918
file

Stone, A., Jones, H., Giles, M., Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2008. Anti-oestrogen therapy switches off tumour suppressors and proapoptotic genes in breast cancer and reveals a new therapeutic opportunity [Abstract]. Breast Cancer Research 10 (s2) , P41. 10.1186/bcr1925
file

Bensmail, Abdelwahab, Hutcheson, Iain Robert, Giles, M., Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2008. Loss of oestrogen receptor alpha in long-term antioestrogen-resistant cells: reversal by a c-src inhibitor [Abstract]. Breast Cancer Research 10 (S2) , O3. 10.1186/bcr1883
file

Habashy, H. O., Powe, D. G., Rakha, E. A., Ball, G., Paish, C., Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Ellis, I. O. 2008. Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance. European Journal of Cancer 44 (11) , pp. 1541-1551. 10.1016/j.ejca.2008.04.020

Hiscox, Stephen Edward and Nicholson, Robert Ian 2008. Src inhibitors in breast cancer therapy. Expert Opinion on Therapeutic Targets 12 (6) , pp. 757-767. 10.1517/14728220802133204

Rakha, E. A., El-Sayed, M. E., Powe, D. G., Green, A. R., Habashy, H., Grainge, M. J., Robertson, J. F. R., Blamey, R., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Lee, A. H. S. and Ellis, I. O. 2008. Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes. European Journal of Cancer 44 (1) , pp. 73-83. 10.1016/j.ejca.2007.10.009

Thompson, A., Brennan, K., Cox, A., Gee, Julia Margaret Wendy, Harcourt, D., Harris, A., Harvie, M., Holen, I., Howell, A., Nicholson, Robert Ian, Steel, M. and Streuli, C. 2008. Evaluation of the current knowledge limitations in breast cancer research: a gap analysis. Breast Cancer Research 10 (2) , R26. 10.1186/bcr1983
file

Zahari, N. M., Taylor, Kathryn Mary and Nicholson, Robert Ian 2008. Functional evaluation of members of the LIV-1 family of proteins and their role in breast cancer. EJC Supplements 6 (12) , p. 184.

Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, Helen Elizabeth, Taylor, Kathryn Mary, Hiscox, Stephen Edward and Gee, Julia Margaret Wendy 2008. Compensatory signalling induced by anti-hormone and anti-growth factor therapies in breast cancer: a starting point for the development of resistance to targeted therapies. In: Pasqualini, Jorge R. ed. Breast cancer: prognosis, treatment and prevention. 2nd ed, London: Informa Healthcare, pp. 123-136.

Hutcheson, Iain Robert, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2008. MAP Kinase family members and endocrine response and survival in breast cancer. In: Walker, Rosemary A. and Thompson, Alastair M. eds. Prognostic and predictive factors in breast cancer. 2nd ed., London: Informa Healthcare, pp. 122-138.

Morgan, Liam David, Nicholson, Robert and Hiscox, Stephen 2008. Src as a therapeutic target in breast cancer. Endocrine‚ Metabolic & Immune Disorders - Drug Targets 8 (4) , pp. 273-278. 10.2174/187153008786848295

Borley, Annabel Catherine, Hiscox, Stephen Edward, Gee, Julia Margaret Wendy, Smith, Chris, Shaw, Victoria, Barrett-Lee, Peter and Nicholson, Robert Ian 2008. Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. Breast Cancer Research 10 (6) , R103. 10.1186/bcr2206
file

Taylor, Kathryn Mary, Jordan, Nicola JAne, Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2008. Zinc transporter HKE4 as a new target in antihormone resistance of breast cancer [Abstract]. Breast Cancer Research 10 (s2) , P42. 10.1186/bcr1926
file

Borley, A. C., Barrett-Lee, Peter, Gee, Julia Margaret Wendy, Show, V. E., Nicholson, Robert and Hiscox, Stephen Edward 2007. Anti-estrogens promote an invasive phenotype in intercellular adhesion deficient breast cancer cells. Breast Cancer Research and Treatment 106 (Supp 1) , S7-S8.

Rampaul, R. S., Ball, G., Paish, C., Pinder, S. E., Mitchell, M. J., Blamey, R. W., Robertson, J. F. R., Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Gullick, W. J. and Ellis, I. O. 2007. O-105 erbB Signalling in breast cancer. EJC Supplements 5 (3) , p. 32. 10.1016/S1359-6349(07)71795-0

Taylor, Kathryn Mary, Morgan, Helen E., Smart, Kathryn, Normawati, Mohamad Zahari, Pumford, Sara Louise, Ellis, Ian O., Robertson, John F. R. and Nicholson, Robert Ian 2007. The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer. Molecular Medicine 13 (7-8) , pp. 396-406.

Assender, J. W., Gee, Julia Margaret Wendy, Lewis, I., Ellis, I. O., Robertson, J. F. R. and Nicholson, Robert Ian 2007. Protein kinase C isoform expression as a predictor of disease outcome on endocrine therapy in breast cancer. Journal of Clinical Pathology 60 (11) , pp. 1216-1221. 10.1136/jcp.2006.041616
file

Greco, F., Vicent, M. J., Gee, S., Jones, Arwyn Tomos, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Duncan, Ruth 2007. Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. Journal of Controlled Release 117 (1) , pp. 28-39. 10.1016/j.jconrel.2006.10.012

Hiscox, Stephen Edward, Green, T. P., Smith, Chris, James, M., Jordan, Nicola Jane and Nicholson, Robert Ian 2007. Combination treatment with AZD0530 and tamoxifen prevents acquired antiestrogen resistance in breast cancer cells [Abstract]. Molecular Cancer Therapeutics 6 (Suppl) , 3411S.

Hiscox, Stephen Edward, Jordan, Nicola Jane, Morgan, Liam David, Green, T. P. and Nicholson, Robert Ian 2007. Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells. Clinical & Experimental Metastasis 24 (3) , pp. 157-167. 10.1007/s10585-007-9065-y

Hutcheson, Iain Robert, Barrow, Denise, Hasmann, M. and Nicholson, Robert Ian 2007. Induction of erbB3/EGFR heterodimers mediates resistance to pertuzumab in a tamoxifen-resistant MCF-7 breast cancer cell line [Abstract]. Molecular Cancer Therapeutics 6 (Suppl) , 3373S.

Hutcheson, Iain Robert, Knowlden, Janice Mary, Hiscox, Stephen Edward, Barrow, Denise, Gee, Julia Margaret Wendy, Robertson, J. F., Ellis, I. O. and Nicholson, Robert Ian 2007. Heregulin beta 1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. Breast Cancer Research 9 (4) , R50. 10.1186/bcr1754
file

Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, H. E., Hiscox, Stephen Edward, Giles, M., Taylor, Kathryn Mary and Gee, Julia Margaret Wendy 2007. Growth factor signalling in endocrine and anti-growth factor resistant breast cancer. Reviews in Endocrine and Metabolic Disorders 8 (3) , pp. 241-253. 10.1007/s11154-007-9033-5

Rakha, E. A., El-Sayed, M. E., Green, A. R., Paish, E. C., Powe, D. G., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Lee, A. H. S., Robertson, J. F. R. and Ellis, I. O. 2007. Biologic and clinical characteristics of breast cancer with single hormone receptor-positive phenotype. Journal of Clinical Oncology 25 (30) , pp. 4772-4778. 10.1200/jco.2007.12.2747

Rampaul, R. S., Paish, C., Pinder, S. E., Going, J. J., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Robertson, J. F. and Ellis, I. O. 2007. Assessment of Her-2 status using a panel of antibodies and FISH. EJC Supplements 5 (3) , p. 17.

Robertson, J. F. R., Semiglazov, V., Nemsadze, G., Dzagnidze, G., Janjalia, M., Nicholson, Robert Ian, Gee, Julia Margaret Wendy and Armstrong, J. 2007. Effects of fulvestrant 250 mg in premenopausal women with oestrogen receptor-positive primary breast cancer. European Journal of Cancer 43 (1) , pp. 64-70. 10.1016/j.ejca.2006.08.019

Khirwadkar, Yamini, Hiscox, Stephen Edward, Jordan, Nicola Jane and Nicholson, Robert Ian 2007. HGF/SF promotes an aggressive phenotype in c-Met-overexpressing fulvestrant-resistant MCF-7 cells - Evidence for MMP-9 and PI3k involvement [Abstract]. Annals of Oncology 18 (S4) , P611. 10.1093/annonc/mdm166

Jones, Helen E., Gee, Julia Margaret Wendy, Hutcheson, Iain Robert, Knowlden, Janice Mary, Barrow, Denise and Nicholson, Robert Ian 2006. Growth factor receptor interplay and resistance in cancer. Endocrine-Related Cancer 13 (S1) , S45-S51. 10.1677/erc.1.01275

Hutcheson, Iain Robert, Knowlden, Janice Mary, Jones, Helen E., Burmi, R. S., McClelland, Richard Andrew, Barrow, Denise, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2006. Inductive mechanisms limiting response to anti-epidermal growth factor receptor therapy. Endocrine-Related Cancer 13 (S1) , S89-S97. 10.1677/erc.1.01279

Gee, Julia Margaret Wendy, Shaw, Victoria E., Hiscox, Stephen Edward, McClelland, Richard Andrew, Rushmere, N. K. and Nicholson, Robert Ian 2006. Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications. Endocrine-Related Cancer 13 (S1) , S77-S88. 10.1677/erc.1.01274

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Harris, A. and Anderson, E. 2006. Consensus Statement. Endocrine-Related Cancer 13 (S1) , S1-S2. 10.1677/erc.1.01323

Hiscox, Stephen Edward, Morgan, Liam David, Green, Tim and Nicholson, Robert 2006. Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer. Endocrine-Related Cancer 13 , S53-S59. 10.1677/erc.1.01297

Hiscox, Stephen Edward, Jordan, Nicola Jane, Jiang, Wen Guo, Harper, Maureen Elaine, McClelland, Richard, Smith, Chris and Nicholson, Robert 2006. Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions. Endocrine-Related Cancer 13 (4) , pp. 1085-1099. 10.1677/erc.1.01270

Burmi, Rajpal Singh, McClelland, Richard Andrew, Barrow, Denise, Ellis, I. O., Robertson, J. F. R., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2006. Microarray studies reveal novel genes associated with endocrine resistance in breast cancer [Abstract]. Breast Cancer Research 8 (S2) , S11. 10.1186/bcr1554
file

Sarwar, N., Kim, J. S., Jiang, J., Peston, D., Sinnett, H. D., Madden, P., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Lykkesfeldt, A. E., Shousha, S., Coombes, R. C. and Ali, S. 2006. Phosphorylation of ER alpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ER alpha phosphorylation in breast cancer progression. Endocrine-Related Cancer 13 (3) , pp. 851-861. 10.1677/erc.1.01123

Jones, Helen E., Gee, Julia Margaret Wendy, Barrow, Denise, Tonge, D., Holloway, B. and Nicholson, Robert Ian 2006. Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells. British Journal of Cancer 95 (2) , pp. 172-180. 10.1038/sj.bjc.6603237

Hiscox, Stephen Edward, Morgan, Liam David, Green, Tim P., Barrow, Denise, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2006. Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast cancer research and treatment 97 (3) , pp. 263-274. 10.1007/s10549-005-9120-9

Cui, Yukin, Parra, Irma, Zhang, Mao, Hilsenbeck, Susan G., Tsimelzon, Anna, Furukawa, Toru, Horii, Akira, Zhang, Zhong-Yin, Nicholson, Robert Ian and Fuqua, Suzanne 2006. Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: A mechanism of Tamoxifen resistance. Cancer Research 66 (11) , pp. 5950-5959. 10.1158/0008-5472.CAN-05-3243

Britton, David James, Hutcheson, Iain Robert, Knowlden, Janice Mary, Barrow, Denise, Giles, Martin Gwyn, McClelland, Richard Andrew, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2006. Bidirectional cross talk between ER alpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Research and Treatment 96 (2) , pp. 131-146. 10.1007/s10549-005-9070-2

Hiscox, Stephen Edward, Jiang, Wen Guo, Obermeier, Kathrin, Taylor, Kathryn Mary, Morgan, Liam David, Burmi, Rajpal Singh, Barrow, Denise and Nicholson, Robert Ian 2006. Tamoxifen-resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of [beta]-catenin phosphorylation. International journal of cancer 118 (2) , pp. 290-301. 10.1002/ijc.21355

Jasani, Bharat, Douglas-Jones, Anthony Gordon, Rhodes, Anthony, Wozniak, Susan, Barrett-Lee, Peter, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2006. Measurement of estrogen receptor status by immunocytochemistry in paraffin wax sections. In: Brooks, S. A. and Harris, A. eds. Breast Cancer Research Protocols, Methods in Molecular Medicine, vol. 120. Totowa, NJ: Humana Press, pp. 127-146. (10.1385/1-59259-969-9:127)

Jones, Helen E., Gee, Julia Margaret Wendy, Barrow, Denise, Holloway, B., Tonge, D. and Nicholson, Robert Ian 2006. Maintenance of EGFR phosphorylation by the IGF-1R in the presence of gefitinib in lung cancer cells: Co-targeting the EGFR and IGF-1R maximises anti-tumour effects [Abstract]. Annals of Oncology 17 (S3) , iii39. 10.1093/annonc/mdl919

Ali, S., Sarwar, N., Jiang, J., Peston, D., Sinnett, H. D., Madden, P., Shousha, S., Lykkesfeldt, A. E., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Kulinskaya, E. and Coombes, R. C. 2006. Immunohistochemical determination of estrogen receptor-alpha phosphorylation in activation function AF1 in primary and tamoxifen-resistant breast cancer is indicative of a complex role for estrogen receptor-alpha phosphorylation in breast cancer progression [Abstract]. Breast Cancer Research and Treatment 100 (S1) , S36-S37. 10.1007/s10549-006-5678-0

Knowlden, Janice Mary, Hutcheson, Iain Robert, Barrow, Denise, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2005. Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor. Endocrinology 146 (11) , pp. 4609-4618. 10.1210/en.2005-0247

Gee, Julia Margaret Wendy, Howell, A., Gullick, W. J., Benz, C. C., Sutherland, R. L., Santen, R. J., Martin, L. A., Ciardiello, F., Miller, W. R., Dowsett, M., Barrett-Lee, Peter, Robertson, J. F. R., Johnston, S. R., Jones, Helen E., Wakeling, A. E., Duncan, R. and Nicholson, Robert Ian 2005. Consensus statement. Endocrine-Related Cancer 12 (S1) , S1-S7. 10.1677/erc.1.01054

Nicholson, Robert Ian, Hutcheson, Iain Robert, Hiscox, Stephen Edward, Knowlden, Janice Mary, Giles, Martin Gwyn, Barrow, Denise and Gee, Julia Margaret Wendy 2005. Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: the use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer. Endocrine-Related Cancer 12 (S1) , S29-S36. 10.1677/erc.1.00991

Staka, Cindy M., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2005. Acquired resistance to oestrogen deprivation: role for growth factor signalling kinases/oestrogen receptor cross-talk revealed in new MCF-7X model. Endocrine-Related Cancer 12 (S1) , S85-S97. 10.1677/erc.1.01006

Jones, Helen E., Gee, Julia Margaret Wendy, Taylor, Kathryn Mary, Barrow, Denise, Williams, Hywel David, Rubini, M. and Nicholson, Robert Ian 2005. Development of strategies for the use of anti-growth factor treatments. Endocrine-Related Cancer 12 (S1) , S173-S182. 10.1677/erc.1.01004

Agrawal, A., Gutteridge, E., Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Robertson, J. F. R. 2005. Overview of tyrosine kinase inhibitors in clinical breast cancer. Endocrine-Related Cancer 12 (S1) , S135-S144. 10.1677/erc.1.01059

Gee, Julia Margaret Wendy, Robertson, J. F., Gutteridge, E., Ellis, I. O., Pinder, S. E., Rubini, M. and Nicholson, Robert Ian 2005. Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocrine-Related Cancer 12 (S1) , S99-S111. 10.1677/erc.1.01005

Gutteridge, E., Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Robertson, J. F. R. 2005. Biological markers associated with response to gefitinib ('Iressa') in patients with breast cancer [Abstract]. British Journal of Surgery 92 (S1) , pp. 13-17. 10.1002/bjs.5008

Green, A. R., Paish, E. C., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Cheung, K. L., Robertson, J. F. R. and Ellis, I. O. 2005. Oestrogen receptor variant expression as potential selectors for adjuvant endocrine therapy in breast cancer patients [Abstract]. Journal of Pathology 205 (S1) , 5A. 10.1002/path.1762

Nicholson, Robert Ian, Hutcheson, Iain Robert, Britton, David James, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Hiscox, Stephen Edward, Barrow, Denise and Gee, Julia Margaret Wendy 2005. Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies. The Journal of Steroid Biochemistry and Molecular Biology 93 (2-5) , pp. 257-262. 10.1016/j.jsbmb.2004.12.006

Giles, Martin Gwyn, Fiegl, H., Widschwendter, M., Gee, Julia Margaret Wendy, Wakeling, A. E. and Nicholson, Robert Ian 2005. Loss of estrogen receptor (ER) expression in MCF-7 cells following long-term exposure to fulvestrant [Abstract]. Breast Cancer Research and Treatment 94 (S1) , S243. 10.1007/s10549-005-1234-6

Hiscox, Stephen Edward, Harper, Maureen Elaine, Jiang, Wen Guo, McClelland, Richard and Nicholson, Robert 2005. Elevated c-met expression accompanies endocrine resistance in MCF7 breast cancer cells and promotes in vitro cell migration and invasion. Breast Cancer Research and Treatment 94 (Supp 1) , S161-S161.

Taylor, Kathryn Mary, Vichova, Petra, Hiscox, Stephen Edward and Nicholson, Robert 2005. Zinc-dependant stimulation of Src, EGFR and IGFR signalling pathways in tamoxifen-resistant breast cancer and the role of zinc transporters. Breast Cancer Research and Treatment 94 (Supp 1) , S162-S162.

Nicholson, Robert Ian, Staka, C., Boyns, Frances Elizabeth, Hutcheson, Iain Robert and Gee, Julia Margaret Wendy 2004. Growth factor-driven mechanisms associated with resistance to estrogen deprivation in breast cancer: new opportunities for therapy. Endocrine-Related Cancer 11 (4) , pp. 623-641. 10.1677/erc.1.00778

Taylor, Kathryn Mary, Hiscox, Stephen Edward and Nicholson, Robert 2004. Zinc transporter LIV-1: a link between cellular development and cancer progression. Trends in Endocrinology and Metabolism 15 (10) , pp. 461-463.

Jones, Helen E., Goddard, Lindy, Gee, Julia Margaret Wendy, Hiscox, Stephen Edward, Rubini, M., Barrow, Denise, Knowlden, Janice Mary, Williams, Sophie E., Wakeling, A. E. and Nicholson, Robert Ian 2004. Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells. Endocrine-Related Cancer 11 (4) , pp. 793-814. 10.1677/erc.1.00799

Jordan, Nicola Jane, Gee, Julia Margaret Wendy, Barrow, Denise, Wakeling, A. E. and Nicholson, Robert Ian 2004. Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells. Breast Cancer Research and Treatment 87 (2) , pp. 167-180. 10.1023/B:BREA.0000041623.21338.47

Gutteridge, E., Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Robertson, J. F. R. 2004. Biological markers associated with response to gefitinib (ZD1839) in patients with breast cancer [Abstract]. Journal of Clinical Oncology 22 (14S) , 648.

Taylor, Kathryn Mary, Johnson, Andrea, Morgan, Helen Elizabeth and Nicholson, Robert Ian 2004. Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transporters. Biochemical Journal 377 (1) , pp. 131-139. 10.1042/BJ20031183

Hiscox, Stephen Edward, Morgan, Liam David, Barrow, Denise, Dutkowski, Carol Mary, Wakeling, Alan and Nicholson, Robert Ian 2004. Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839). Clinical & Experimental Metastasis 21 (3) , pp. 201-212. 10.1023/B:CLIN.0000037697.76011.1d

Rushmere, N. K., Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Harper, Maureen Elaine, Robertson, J. F. R., Morgan, Bryan Paul and Nicholson, Robert Ian 2004. Analysis of the level of mRNA expression of the membrane regulators of complement, Cd59, Cd55 and Cd46, in breast, cancer. International Journal of Cancer 108 (6) , pp. 930-936. 10.1002/ijc.11606

Hutcheson, Iain Robert, Gee, Julia Margaret Wendy, Barrow, Denise, Jones, Helen E., Wakeling, A. E. and Nicholson, Robert Ian 2004. Treatment of tamoxifen-resistant MCF-7 breast cancer cells with either gefitinib ('Iressa') or trastuzumab (Herceptin((R))) generates cross-resistant phenotypes [Abstract]. Breast Cancer Research and Treatment 88 (S1) , S145-S146. 10.1007/s10549-004-3602-z

Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward, Barrow, Denise and Gee, Julia Margaret Wendy 2004. Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination. Clinical Cancer Research 10 (1) , 346s-354s. 10.1158/1078-0432.CCR-031206

Gee, Julia Margaret Wendy, Gutteridge, E., Robertson, J. F., Wakeling, A. E., Jones, Helen E. and Nicholson, Robert Ian 2004. Biological markers during early treatment of tamoxifen resistant breast cancer with gefitinib ('Iressa')[Abstract]. Breast Cancer Research and Treatment 88 (S1) , S32. 10.1007/s10549-004-3602-z

Giles, Martin Gwyn, Gee, Julia Margaret Wendy, Wakeling, A. E. and Nicholson, Robert Ian 2004. Characterization of ER alpha and cofactor recruitment during fulvestrant treatment and resistance in breast cancer using chromatin immunoprecipitation [Abstract]. Breast Cancer Research and Treatment 88 (S1) , S216-S217. 10.1007/s10549-004-3602-z

Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Britton, David James, Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward, Barrow, Denise and Gee, Julia Margaret Wendy 2004. Chapter 16: beyond antihormones in the targeted therapy of breast cancer. In: Ingle, James N. and Dowsett, Mitchell eds. Endocrine Therapy for Breast Cancer Proceedings of the 2003 Gleneagles Conference, New York: Marcel Dekker, pp. 249-258.

Gee, Julia Margaret Wendy, Giles, Martin Gwyn and Nicholson, Robert Ian 2004. Extreme growth factor signalling can promote oestrogen receptor-alpha loss: therapeutic implications in breast cancer. Breast Cancer Research 6 (4) , pp. 162-163. 10.1186/bcr904
file

Hutcheson, Iain Robert, Knowlden, Janice Mary, Madden, Tracie-Ann, Barrow, Denise, Gee, Julia Margaret Wendy, Wakeling, A. E. and Nicholson, Robert Ian 2003. Oestrogen receptor-mediated modulation of the EGFR/MAPK pathway in tamoxifen-resistant MCF-7 cells. Breast Cancer Research and Treatment 81 (1) , pp. 81-93. 10.1023/A:1025484908380

Taylor, Kathryn Mary, Hadley, Lisa J, Johnson, Andrea, Morgan, Helen Elizabeth and Nicholson, Robert Ian 2003. Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. Biochemical Journal 375 (1) , pp. 51-59. 10.1042/BJ20030478

Clark, Jill Helen, Broadley, Kenneth John, Hutcheson, Iain Robert, Nicholson, Robert Ian and Kidd, Emma Jane 2003. Expression of adenosine receptors in MCF-7 human breast cancer cells [Abstract]. British Journal of Pharmacology 138 , U65.

Knowlden, Janice Mary, Hutcheson, Iain Robert, Jones, Helen E., Madden, Tracie-Ann, Gee, Julia Margaret Wendy, Harper, Maureen Elaine, Barrow, Denise, Wakeling, A. E. and Nicholson, Robert Ian 2003. Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells. Endocrinology 144 (3) , pp. 1032-1044. 10.1210/en.2002-220620

Hutcheson, Iain Robert, Knowlden, Janice Mary, Barrow, Denise, Gee, Julia Margaret Wendy, Robertson, J. F., Wakeling, A. E. and Nicholson, Robert Ian 2003. Heregulin-induced AKT activation promotes growth of gefitinib ('Iressa', ZD1839)-treated, tamoxifen-resistant breast cancer cells [Abstract]. Breast Cancer Research and Treatment 82 (S1) , S170. 10.1023/A:1026252325164

Nicholson, Robert Ian, Jones, Helen E., Gee, Julia Margaret Wendy, Barrow, Denise, Hiscox, Stephen Eward, Harper, Maureen Elaine, Rubini, M., Guy, S. and Wakeling, A. E. 2003. Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib ('Iressa', ZD1839) in MCF-7 human breast cancer cells [Abstract]. Breast Cancer Research and Treatment 82 (S1) , S171. 10.1023/A:1026252325164

Britton, D. J., Hutcheson, Iain Robert, Barrow, Denise, McClelland, Richard Andrew, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2003. Oestrogen receptor phosphorylation in hormone sensitive and anti-hormone resistant breast cancer cells [Abstract]. Breast Cancer Research and Treatment 82 (S1) , S61. 10.1023/A:1026252325164

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Knowlden, Janice Mary, McClelland, Richard Andrew, Madden, Tracie-Ann, Barrow, Denise and Hutcheson, Iain Robert 2003. The biology of antihormone failure in breast cancer. Breast Cancer Research and Treatment 80 (S1) , pp. 29-34. 10.1023/A:1025467500433

Gee, Julia Margaret Wendy, Rubini, M., Robertson, J. F., Ellis, I. O., Gutteridge, E. and Nicholson, Robert Ian 2003. Type 1 insulin-like growth factor receptor expression and activation in clinical breast cancer [Abstract]. Breast Cancer Research and Treatment 82 (S1) , S102. 10.1023/A:1026252325164

Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2003. Expanding the therapeutic repertoire of epidermal growth factor receptor blockade: radiosensitization [Commentary]. Breast Cancer Research 5 (3) , pp. 126-129. 10.1186/bcr584
file

Hutcheson, Iain Robert, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2003. MAP Kinase family members and endocrine response and survival in breast cancer. In: Walker, R. A. ed. Prognostic and Predictive Factors in Breast Cancer, London: Martin Dunitz, pp. 147-166.

Gee, Julia Margaret Wendy, Harper, Maureen Elaine, Hutcheson, Iain Robert, Madden, Tracie-Ann, Barrow, Denise, Knowlden, Janice Mary, McClelland, Richard Andrew, Jordan, Nicola Jane, Wakeling, A. E. and Nicholson, Robert Ian 2002. ZD1839 ('Iressa') improves the antitumour activity of tamoxifen ('Nolvadex') and ICI 182, 780 ('Faslodex') in antihormone responsive breast cancer [Abstract]. European Journal of Cancer 38 (S7) , S59. 10.1016/S0959-8049(02)80835-8

Clark, Jill Helen, Martin, Timothy John, Yates, Lisa, Kidd, Emma Jane, Nicholson, Robert Ian and Broadley, Kenneth John 2002. Characterisation of transfected human adenosine A3 receptors [Abstract]. British Journal of Pharmacology 136

Nicholson, Robert Ian, Hutcheson, Iain Robert and Gee, Julia Margaret Wendy 2002. Targeting of oestrogen and growth factor signalling pathways in the therapy of breast cancer: Implications for chemoprevention [Abstract]. European Journal of Cancer 38 (S3) , S43-S44. 10.1016/S0959-8049(02)81245-X

Clark, Jill Helen, Broadley, Kenneth John, Hutcheson, Iain Robert, Nicholson, Robert Ian and Kidd, Emma Jane 2002. Adenosine receptor agonists mediate the phosphorylation of mitogen activated protein kinase (MAPK) in MCF-7 human breast cancer cells [Abstract]. British Journal of Pharmacology 135

Nicholson, Robert Ian, Hutcheson, Iain Robert, Harper, Maureen Elaine, Knowlden, Janice Mary, Barrow, Denise, McClelland, Richard Andrew, Jones, Helen E., Wakeling, A. E. and Gee, Julia Margaret Wendy 2002. Modulation of epidermal growth factor receptor in endocrine-resistant, estrogen-receptor-positive breast cancer. In: Castagnetta, L., Agostara, B., Massimo, L., Montalto, G. and Bradlow, H. L. eds. Hormone-Related Tumors: Novel Approaches to Prevention and Treatment, Annals of the New York Academy of Sciences, vol. 963. New York: The New York Academy of Sciences, pp. 104-115. (10.1111/j.1749-6632.2002.tb04101.x)

Albanell, Joan, Rojo, Federico, Averbuch, Steve, Feyereislova, Andrea, Mascaro, Jose Manuel, Herbst, Roy, Lo Russo, Patricia, Rischin, Danny, Sauleda, Silvia, Gee, Julia Margaret Wendy, Nicholson, Robert Ian and Baselga, Jose 2002. Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition. Journal of Clinical Oncology 20 (1) , pp. 110-124. 10.1200/JCO.20.1.110

Chan, Kai C., Knox, W. Fiona, Gee, Julia Margaret Wendy, Morris, Julia, Nicholson, Robert Ian, Potten, Christopher S. and Bundred, Nigel J. 2002. Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast. Cancer Research 62 , pp. 122-128.

Wakeling, A. E., Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2001. Prospects for combining hormonal and nonhormonal growth factor inhibition. Clinical Cancer Research 7 (12) , 4350S-4355S.

Nicholson, Robert Ian, Harper, Maureen Elaine, Hutcheson, Iain Robert, Madden, Tracie-Ann, Barrow, Denise, Knowlden, Janice Mary, Jordan, Nicola Jane, Wakeling, A. E. and Gee, Julia Margaret Wendy 2001. ZD1839 (Iressa) improves the antitumor activity of tamoxifen (Nolvadex) in antihormone-responsive breast cancer cells [Abstract]. Clinical Cancer Research 7 (S) , 3766S.

Glynne-Jones, Eveline Marie, Harper, Maureen Elaine, Seery, Liam Thomas, James, Rhianedd, Anglin, Ian Edward, Morgan, Helen E., Taylor, Kathryn Mary, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2001. TENB2, a proteoglycan identified in prostate cancer that is associated with disease progression and androgen independence. International Journal of Cancer 94 (2) , pp. 178-184. 10.1002/ijc.1450

Nicholson, Robert Ian, Gee, Julia Margaret Wendy and Harper, Maureen Elaine 2001. EGFR and cancer prognosis. European Journal of Cancer 37 (S4) , pp. 9-15. 10.1016/S0959-8049(01)00231-3

Nicholson, Robert Ian, Hutcheson, Iain Robert, Harper, Maureen Elaine, Knowlden, Janice Mary, Barrow, Denise, McClelland, Richard Andrew, Jones, Helen E., Wakeling, A. E. and Gee, Julia Margaret Wendy 2001. Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer. Endocrine-Related Cancer 8 (3) , pp. 175-182. 10.1677/erc.0.0080175

Nicholson, Robert Ian, Anderson, E, Bundred, NJ and Robertson, JF 2001. Comparison of the short-term biological effects of 7α -[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17 β-diol (Faslodex) versus Tamoxifen in postmenopausal women with primary breast cancer. Cancer Research 61 (18) , pp. 6739-6746.

Nicholson, Robert Ian, Albanell, J, Codony-Servat, J, Rojo, F, Del Campo, J. M., Mendelsohn, J., Baselga, J., Sauleda, S., Anido, J., Raspall, G., Giralt, J. and Roselló, J. 2001. Activated extracellular signal-regulated kinases: association with epidermal growth factor receptor/transforming growth factor α expression in head and neck squamous carcinoma and inhibition by anti- epidermal growth factor receptor treatments. Cancer Research 61 (17) , pp. 6500-6510.

Robertson, J. F., Nicholson, Robert Ian, Bundred, N. J., Anderson, E., Rayter, Z., Dowsett, M., Fox, J. N., Gee, Julia Margaret Wendy, Webster, A., Wakeling, A. E., Morris, C. and Dixon, M. 2001. Comparison of the short-term biological effects of 7 alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17 beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Research 61 (18) , pp. 6739-6746.

McClelland, Richard Andrew, Barrow, Denise, Madden, Tracie-Ann, Dutkowski, Carol Mary, Pamment, Joanna Susan, Knowlden, Janice Mary, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2001. Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology 142 (7) , pp. 2776-2788. 10.1210/en.142.7.2776

Kenny, F. S., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Ellis, I. O., Morris, T. M., Watson, S. A., Bryce, R. P. and Robertson, J. F. R. 2001. Effect of dietary GLA plus /-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. International Journal of Cancer 92 (3) , pp. 342-347. 10.1002/ijc.1213

Kenny, F. S., Willsher, P. C., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Pinder, S. E., Ellis, I. O. and Robertson, J. F. R. 2001. Change in expression of ER, bcl-2 and MIB1 on primary tamoxifen and relation to response in ER positive breast cancer. Breast Cancer Research and Treatment 65 (2) , pp. 135-144. 10.1023/A:1006469627067

Yip, S. S., Crew, A. J., Gee, Julia Margaret Wendy, Hui, R., Blamey, R. W., Robertson, J. F. R., Nicholson, Robert Ian, Sutherland, R. L. and Daly, R. J. 2000. Up-regulation of the protein tyrosine phosphatase SHP-1 in human breast cancer and correlation with GRB2 expression. International Journal of Cancer 88 (3) , pp. 363-368. 10.1002/1097-0215(20001101)88:3<363::AID-IJC7>3.0.CO;2-4

Madden, Tracie-Ann, Barrow, Denise, McClelland, Richard Andrew, Gee, Julia Margaret Wendy and Nicholson, Robert Ian 2000. Modulation of oestrogen action by receptor gene inhibition. European Journal of Cancer 36 (S4) , pp. 34-35. 10.1016/S0959-8049(00)00216-1

Kenny, F. S., Pinder, S. E., Ellis, I. O., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Bryce, R. P. and Robertson, J. F. R. 2000. Gamma linolenic acid with tamoxifen as primary therapy tn breast cancer. International Journal of Cancer 85 (5) , pp. 643-648. 10.1002/(SICI)1097-0215(20000301)85:5<643::AID-IJC8>3.0.CO;2-Z

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Robertson, J. F. R., Ellis, I. O. and Nicholson, Robert Ian 2000. A possible divergent role for the oestrogen receptor alpha and beta subtypes in clinical breast cancer. International Journal of Cancer 89 (2) , pp. 209-212. 10.1002/(SICI)1097-0215(20000320)89:2<209::AID-IJC17>3.0.CO;2-6

Gee, Julia Margaret Wendy, Barroso, A. F., Ellis, I. O., Robertson, J. F. R. and Nicholson, Robert Ian 2000. Biological and clinical associations of c-jun activation in human breast cancer. International Journal of Cancer 89 (2) , pp. 177-186. 10.1002/(SICI)1097-0215(20000320)89:2<177::AID-IJC13>3.0.CO;2-0

Nicholson, Robert Ian and Gee, Julia Margaret Wendy 2000. Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer. British Journal of Cancer 82 (3) , pp. 501-513. 10.1054/bjoc.1999.0954

Gee, Julia Margaret Wendy, Robertson, J. F. R., Ellis, I. O. and Nicholson, Robert Ian 2000. Abstract P13: Impact of activation of MAP kinase family members on endocrine response and survival in clinical breast cancer [Abstract]. European Journal of Cancer 36 (S4) , p. 105. 10.1016/S0959-8049(00)00259-8

Gee, Julia Margaret Wendy, Robertson, J. F. R., Ellis, I. O., Nicholson, Robert Ian and Hurst, H. C. 1999. Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer. Journal of Pathology 189 (4) , pp. 514-520. 10.1002/(SICI)1096-9896(199912)189:4<514::AID-PATH463>3.0.CO;2-9

Seery, Liam T., Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Robertson, J. F. R., Kenny, F. S., Ellis, I. O. and Nicholson, Robert Ian 1999. [Corrigendum] BRCA1 expression levels predict distant metastasis of sporadic breast cancer (vol 84, pg 258, 1999). International Journal of Cancer 84 (5) , p. 544. 10.1002/(SICI)1097-0215(19991022)84:5<544::AID-IJC18>3.0.CO;2-9

Nicholson, Robert Ian, McClelland, Richard Andrew, Robertson, J. F. R. and Gee, Julia Margeret Wendy 1999. Involvement of steroid hormone and growth factor cross-talk in endocrine response in breast cancer. Endocrine-Related Cancer 6 (3) , pp. 373-387. 10.1677/erc.0.0060373

Kenny, F. S., Hui, R., Musgrove, E. A., Gee, Julia Margaret Wendy, Blamey, R. W., Nicholson, Robert Ian, Sutherland, R. L. and Robertson, J. F. R. 1999. Overexpression of cyclin D1 messenger RNA predicts for poor prognosis in estrogen receptor-positive breast cancer. Clinical Cancer Research 5 (8) , pp. 2069-2076.

McClelland, Richard Andrew, Gee, Julia Margaret Wendy, O'Sullivan, Louise A., Barnes, D. M., Robertson, J. F. R., Ellis, I. O. and Nicholson, Robert Ian 1999. p21(WAF1) expression and endocrine response in breast cancer. Journal of Pathology 188 (2) , pp. 126-132. 10.1002/(SICI)1096-9896(199906)188:2<126::AID-PATH340>3.0.CO;2-O

Seery, Liam T., Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Robertson, J. F. R., Kenny, F. S., Ellis, I. O. and Nicholson, Robert Ian 1999. BRCA1 expression levels predict distant metastasis of sporadic breast cancers. International Journal of Cancer 84 (3) , pp. 258-262. 10.1002/(SICI)1097-0215(19990621)84:3<258::AID-IJC10>3.0.CO;2-H

Davies, E. L., Gee, Julia Margaret Wendy, Cochrane, Richard A., Jiang, Wen Guo, Sharma, A. K., Nicholson, Robert Ian and Mansel, Robert Edward 1999. The immunohistochemical expression of desmoplakin and its role in vivo in the progression and metastasis of breast cancer. European Journal of Cancer 35 (6) , pp. 902-907. 10.1016/S0959-8049(99)00031-3

Gee, Julia Margaret Wendy, Willsher, P. C., Kenny, F. S., Robertson, J. F. R., Pinder, S. E., Ellis, I. O. and Nicholson, Robert Ian 1999. Endocrine response and resistance in breast cancer: A role for the transcription factor Fos. International Journal of Cancer 84 (1) , pp. 54-61. 10.1002/(SICI)1097-0215(19990219)84:1<54::AID-IJC11>3.0.CO;2-X

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Seery, L. T., Farrow, Lynne, Gullick, W. J., Ellis, I. O., Blamey, R. W., Robertson, J. F. R. and Nicholson, Robert Ian 1998. C-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer. Oncogene 17 (15) , pp. 1949-1957.

Kenny, F. S., Willsher, P. C., Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Ellis, I. O. and Robertson, J. F. R. 1998. Change in expression of ER and BCL-2 predict for quality and duration of response in endocrine sensitive breast cancer [Abstract]. European Journal of Cancer 34 (S5) , S82. 10.1016/S0959-8049(98)80345-6

Willsher, P. C., Pinder, S. E., Gee, Julia Margaret Wendy, Ellis, I. O., Chan, S. Y., Nicholson, Robert Ian, Blamey, R. W. and Robertson, J. F. R. 1998. c-erbB2 expression predicts response to preoperative chemotherapy for locally advanced breast cancer. Anticancer Research 18 (5B) , pp. 3695-3698.

Davies, E. L., Gee, Julia Margaret Wendy, Cochrane, R. A., Nicholson, Robert Ian, Sharma, A. K., Jiang, Wen Guo and Mansel, R. E. 1998. The expression of desmoglein-2 in primary breast cancer and its relation to a series of prognostic markers [Abstract]. British Journal of Cancer 78 (2) , p. 149. 10.1038/bjc.1998.457

McClelland, Richard Andrew, Manning, D. L., Gee, Julia Margaret Wendy, Willsher, P., Robertson, J. F. R., Ellis, I. O., Blamey, R. W. and Nicholson, Robert Ian 1998. Oestrogen-regulated genes in breast cancer: association of pLIV1 with response to endocrine therapy. British Journal of Cancer 77 (10) , pp. 1653-1656. 10.1038/bjc.1998.457

Knowlden, Janice Mary, Gee, Julia Margaret Wendy, Bryant, S., McClelland, Richard Andrew, Manning, D. L., Mansel, R., Ellis, I. O., Blamey, R. W., Robertson, J. F. R. and Nicholson, Robert Ian 1997. Use of reverse transcription-polymerase chain reaction methodology to detect estrogen-regulated gene expression in small breast cancer specimens. Clinical Cancer Research 3 (11) , pp. 2165-2172.

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Harper, Maureen Elaine, Ellis, I. O., Willsher, P. and Robertson, J. F. R. 1997. erbB signalling in clinical breast cancer: relationship to endocrine sensitivity. Endocrine-Related Cancer 4 (3) , pp. 297-305. 10.1677/erc.0.0040297

Sharma, A. K., Grimshaw, D., Horgan, K., Neades, G. T., Gee, Julia Margaret Wendy, Douglas-Jones, Anthony Gordon, Mansel, R. E. and Nicholson, Robert Ian 1996. Analysis of the genes for oestrogen and epidermal growth factor receptors in human breast cancer. The Breast 5 (5) , pp. 344-350. 10.1016/S0960-9776(96)90002-8

Sharma, A. K., Grimshaw, D., Horgan, K., Mansel, R. E., Gee, Julia Margaret Wendy and Nicholson, Robert Ian 1996. Mechanisms responsible for oestrogen receptor expression in primary human breast cancer. The Breast 5 (4) , pp. 237-243. 10.1016/S0960-9776(96)90017-X

Nicholson, Robert Ian, Francis, A. B., Kyme, Susan R. and Gee, Julia Margaret Wendy 1996. Properties and mode of action of pure antioestrogens in breast cancer in vitro. The Breast 5 (3) , pp. 175-180. 10.1016/S0960-9776(96)90089-2

McClelland, Richard Andrew, Gee, Julia Margaret Wendy, Francis, A. B., Robertson, J. F. R., Blamey, R. W., Wakeling, A. E. and Nicholson, Robert Ian 1996. Short-term effects of pure anti-oestrogen ICI 182780 treatment on oestrogen receptor, epidermal growth factor receptor and transforming growth factor-alpha protein expression in human breast cancer. European Journal of Cancer 32 (3) , pp. 413-416. 10.1016/0959-8049(95)00517-X

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Bryant, S., Francis, A. B., McClelland, Richard Andrew, Knowlden, Janice Mary, Wakeling, A. E. and Osborne, C. K. 1996. Pure antiestrogens - The most important advance in the endocrine therapy of breast cancer since 1896? In: Castagnetta, L., Nenci, I. and Bradlow, H. L. eds. Basis for Cancer Management, Annals of the New York Academy of Sciences, vol. 784. New York: New York Academy of Sciences, pp. 325-335. (10.1111/j.1749-6632.1996.tb16247.x)

McClelland, Richard Andrew, Manning, D. L., Gee, Julia Margaret Wendy, Anderson, E., Clarke, R., Howell, A., Dowsett, M., Robertson, J. E., Blamey, R. W., Wakeling, A. E. and Nicholson, Robert Ian 1996. Effects of short-term antiestrogen treatment of primary breast cancer on estrogen receptor mRNA and protein expression and on estrogen-regulated genes. Breast Cancer Research and Treatment 41 (1) , pp. 31-41. 10.1007/BF01807034

Gee, Julia Margaret Wendy, Douglas-Jones, Anthony Gordon, Hepburn, P., Sharma, A. K., McClelland, Richard Andrew, Ellis, I. O. and Nicholson, Robert Ian 1995. A cautionary note regarding the application of Ki-67 antibodies to paraffin-embedded breast cancers. Journal of Pathology 177 (3) , pp. 285-293. 10.1002/path.1711770311

Nicholson, Robert Ian, McClelland, Richard Andrew and Gee, Julia Margaret Wendy 1995. Steroid hormone receptors and their clinical significance in cancer. Journal of Clinical Pathology 48 (10) , pp. 890-895. 10.1136/jcp.48.10.890
file

Gee, Julia Margaret Wendy, Ellis, I. O., Robertson, J. F. R., Willsher, P., McClelland, Richard Andrew, Hewitt, K. N., Blamey, R. W. and Nicholson, Robert Ian 1995. Immunocytochemical localization of fos protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy. International Journal of Cancer 64 (4) , pp. 269-273. 10.1002/ijc.2910640410

Robertson, J. F. R., Gee, Julia Margaret Wendy, McClelland, Richard Andrew, Ellis, I. O., Willsher, P., Blamey, R. W. and Nicholson, Robert Ian 1995. BCL2 Expression In Breast-Cancer - Identification Of Patients Who Should Not Receive Endocrine Therapy [Abstract]. British Journal of Surgery 82 (5) , p. 698. 10.1002/bjs.1800820540

Manning, D. L., McClelland, Richard Andrew, Knowlden, Janice Mary, Bryant, S., Gee, Julia Margaret Wendy, Green, C. D., Robertson, J. F. R., Blamey, R. W., Sutherland, R. L., Ormandy, C. J. and Nicholson, Robert Ian 1995. Differential expression of estrogen-regulated genes in breast-cancer. Acta Oncologica 34 (5) , pp. 641-646.

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Francis, A. B., Manning, D. L., Wakeling, A. E. and Katzenellenbogen, B. S. 1995. Observations arising from the use of pure antioestrogens on oestrogen-responsive (MCF-7) and oestrogen growth-independent (K3) human breast cancer cells. Endocrine-Related Cancer 2 (1) , pp. 115-121. 10.1677/erc.0.0020115

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Manning, D. L., Wakeling, A. E., Montano, M. M. and Katzenellenbogen, B. S. 1995. Responses to Pure Antiestrogens (ICI 164384, ICI182780) in Estrogen-Sensitive and-Resistant Experimental and Clinical Breast Cancer. In: Philibert, D., Roy, A. K., Teutsch, G. and Henderson, D. eds. Steroid Receptors and Antihormones, Annals of the New York Academy of Sciences, vol. 761. New York: New York Academy of Sciences, pp. 148-163. (10.1111/j.1749-6632.1995.tb31376.x)

Gee, Julia Margaret Wendy, Robertson, J. F. R., Ellis, I. O., Willsher, P., McClelland, Richard Andrew, Hoyle, H. B., Kyme, S. R., Finlay, Pauline, Blamey, R. W. and Nicholson, Robert Ian 1994. Immunocytochemical localization of BCL-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy. International Journal of Cancer 59 (5) , pp. 619-628. 10.1002/ijc.2910590508

Nicholson, Robert Ian, McClelland, Richard Andrew, Gee, Julia Margaret Wendy, Manning, D. L., Cannon, P., Robertson, J. F. R., Ellis, I. O. and Blamey, R. W. 1994. Transforming growth factor-α and endocrine sensitivity in breast cancer. Cancer Research 54 (7) , pp. 1684-1689.

Nicholson, Robert Ian, McClelland, Richard Andrew, Gee, Julia Margaret Wendy, Manning, David L., Cannon, P., Robertson, J. F. R., Ellis, I. O. and Blamey, R. W. 1994. Epidermal growth factor receptor expression in breast cancer: Association with response to endocrine therapy. Breast Cancer Research and Treatment 29 (1) , pp. 117-125. 10.1007/BF00666187

Manning, D. L., Robertson, J. F. R., Ellis, I. O., Elston, C. W., McClelland, Richard Andrew, Gee, Julia Margaret Wendy, Jones, R. J., Green, C. D., Cannon, P., Blamey, R. W. and Nicholson, Robert Ian 1994. Oestrogen-regulated genes in breast cancer: Association of pLIV1 with lymph node involvement. European Journal of Cancer 30 (5) , pp. 675-678. 10.1016/0959-8049(94)90543-6

Nicholson, Robert Ian, Francis, A. B., McClelland, Richard Andrew, Manning, D. L. and Gee, Julia Margaret Wendy 1994. Pure anti-oestrogens (ICI 164384 and ICI 182780) and breast cancer: is the attainment of complete oestrogen withdrawal worthwhile? Endocrine-Related Cancer 1 (4) , pp. 5-17. 10.1677/erc.0.0010005

Nicholson, Robert Ian, Gee, Julia Margaret Wendy, Eaton, C. L., Manning, D. L., Mansel, R. E., Sharma, A. K., Douglas-Jones, Anthony Gordon, Price-Thomas, M., Howell, A., Defriend, D. J., Bundred, N. J., Anderson, E., Robertson, J. F. R., Blamey, R. W., Dowsett, M., Baum, M., Walton, P. and Wakeling, A. E. 1994. Pure antioestrogens in breast cancer - experimental and clinical observations. Presented at: Sex Hormones and Antihormones in Endocrine Dependent Pathology: Basic and Clinical Aspects: International Symposium, Milano, Italy, 10-14 April 1994. Published in: Motta, M. and Serio, M. eds. Sex Hormones and Antihormones in Endocrine Dependent Pathology: Basic and Clinical Aspects: Proceedings of an International Symposium, Milano, Italy, 10-14 April 1994. International Congress Series , vol. 1064. Amsterdam: Elsevier Science, pp. 347-360.

Schmid, K. W., Ellis, I. O., Gee, Julia Margaret Wendy, Darke, Barbara M., Lees, W. E., Kay, John, Cryer, Anthony, Stark, J. M., Hittmair, A., Öfner, D., Dünser, M., Margreiter, R., Daxenbichler, G., Nicholson, Robert Ian, Bier, B., Böcker, W. and Jasani, Bharat 1993. Presence and possible significance of immunocytochemically demonstrable metallothionein over-expression in primary invasive ductal carcinoma of the breast. Virchovs Archiv 422 (2) , pp. 153-159. 10.1007/BF01607167

Manning, D. L., McClelland, Richard Andrew, Gee, Julia Margaret Wendy, Chan, C. M. W., Green, C. D., Blamey, R. M. and Nicholson, Robert Ian 1993. The role of four oestrogen-responsive genes, pLIV1, pS2, pSYD3 and pSYD8, in predicting responsiveness to endocrine therapy in primary breast cancer. European Journal of Cancer 29 (10) , pp. 1462-1468. 10.1016/0959-8049(93)90021-7

Gee, Julia Margaret Wendy, Amselgruber, W. M., Jasani, Bharat and Nicholson, Robert Ian 1991. Use of the dinitrophenyl hapten sandwich staining procedure (DHSS) to localize estrogen receptors in paraffin-embedded tissues. Journal of Histochemistry & Cytochemistry 39 (12) , pp. 1659-1670. 10.1177/39.12.1719072

Nicholson, Robert Ian, Walker, Kate J., Bouzubar, N., Wills, R. J., Gee, Julia Margaret Wendy, Rushmere, N. K. and Davies, P. 1990. Estrogen Deprivation in Breast Cancer: Clinical, Experimental, and Biological Aspects. In: Castagnetta, L., D'Aquino, S., Labrie, F. and Bradlow, H. L. eds. Steroid Formation, Degradation, and Action in Peripheral Tissues, Annals of the New York Academy of Sciences, vol. 595. New York: New York Academy of Sciences, pp. 316-327. (10.1111/j.1749-6632.1990.tb34305.x)

Gee, Julia Margaret Wendy, Nicholson, Robert Ian, Jasani, Bharat, Newman, G. R. and Amselgruber, W. M. 1990. An immunocytochemical method for localization of estrogen receptors in rat tissues using a dinitrophenyl (DNP)-labeled rat monoclonal primary antibody. Journal of Histochemistry & Cytochemistry 38 (1) , pp. 69-78. 10.1177/38.1.1688451

Nicholson, Robert Ian, Gotting, K. E., Gee, Julia Margaret Wendy and Walker, Kate J. 1988. Actions of oestrogens and antioestrogens on rat mammary gland development: Relevance to breast cancer prevention. Journal of Steroid Biochemistry 30 (1-6) , pp. 95-103. 10.1016/0022-4731(88)90081-7

This list was generated on Sun Aug 18 09:11:48 2019 BST.