Browse by All Cardiff Authors

Ipseiz, Natacha, Pickering, Robert J., Rosas, Marcela, Tyrrell, Victoria J., Davies, Luke C., Orr, Selinda J., Czubala, Magdalena A., Fathalla, Dina, Robertson, Avril A. B., Bryant, Clare E., O'Donnell, Valerie and Taylor, Philip R. 2020. Tissue‐resident macrophages actively suppress IL‐1beta release via a reactive prostanoid/IL‐10 pathway. EMBO Journal 39 (14) , e103454. 10.15252/embj.2019103454

Ipseiz, Natacha, Czubala, Magdalena A., Bart, Valentina M.T., Davies, Luke C., Jenkins, Robert H., Brennan, Paul and Taylor, Philip R. 2020. Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors. Molecular Therapy - Methods and Clinical Development 16 , pp. 21-31. 10.1016/j.omtm.2019.10.004

Thompson, Aiysha, Griffiths, James S., Walker, Louise, Matos da Fonseca, Diogo, Lee, Keunsook K., Taylor, Philip R., Gow, Neil A. R. and Orr, Selinda J. 2019. Dependence on Dectin-1 varies with multiple candida species. Frontiers in Microbiology 10 , 1800. 10.3389/fmicb.2019.01800

Zelek, Wioleta M., Taylor, Philip R. and Morgan, B. Paul 2019. Development and characterisation of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species. Immunology 157 (4) , pp. 283-295. 10.1111/imm.13083

Thompson, Aiysha, Davies, Luke C., Liao, Chia-Te, da Fonseca, Diogo M., Griffiths, James S., Andrews, Robert, Jones, Adam V., Clement, Mathew, Brown, Gordon D., Humphreys, Ian R., Taylor, Philip R. and Orr, Selinda J. 2019. The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors. PLoS Pathogens 15 (6) , e1007850. 10.1371/journal.ppat.1007850

Twohig, Jason P., Cardus Figueras, Ana, Andrews, Robert, Wiede, Florian, Cossins, Benjamin C., Derrac Soria, Alicia, Lewis, Myles J., Townsend, Michael J., Millrine, David, Li, Jasmine, Hill, David G., Uceda Fernandez, Javier, Liu, Xiao, Szomolay, Barbara, Pepper, Christopher J., Taylor, Philip R., Pitzalis, Costantino, Tiganis, Tony, Williams, Nigel M., Jones, Gareth W. and Jones, Simon A. 2019. Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells. Nature Immunology 20 , pp. 458-470. 10.1038/s41590-019-0350-0

Cabron, Anne-Sophie, El azzouzi, Karim, Boss, Melanie, Arnold, Philipp, Schwarz, Jeanette, Rosas, Marcela, Dobert, Jan Philipp, Pavlenko, Egor, Schumacher, Neele, Renné, Thomas, Taylor, Philip R., Linder, Stefan, Rose-John, Stefan and Zunke, Friederike 2018. Structural and functional analyses of the shedding protease ADAM17 in HoxB8-Immortalized macrophages and dendritic-like cells. Journal of Immunology 201 (10) , pp. 3106-3118. 10.4049/jimmunol.1701556

Griffiths, James S., Thompson, Aiysha, Stott, Matthew, Benny, Ankita, Lewis, Natalie A., Taylor, Philip R., Forton, Julian, Herrick, Sarah, Orr, Selinda J. and McGreal, Eamon P. 2018. Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases. FASEB Journal 32 (6) , pp. 3385-3397. 10.1096/fj.201701145R

Davies, Luke, Rice, Christopher M., Palmieri, Erika M., Taylor, Philip, Kuhns, Douglas B. and McVicar, Daniel W. 2017. Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels. Nature Communications 8 (1) , 2074. 10.1038/s41467-017-02092-0

Singh, Ravinder, Perks, William, Twohig, Jason, Kidd, Emma, Broadley, Kenneth, Farrow, S N, Williams, Anwen, Taylor, Philip and Wang, Edward 2017. Death receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation. Cellular Immunology 320 , pp. 62-70. 10.1016/j.cellimm.2017.09.005

Prince, Lynne R., Prosseda, Svenja D., Higgins, Kathryn, Carlring, Jennifer, Prestwich, Elizabeth C., Ogryzko, Nikolay V., Rahman, Atiqur, Basra, Alexander, Falciani, Francesco, Taylor, Philip, Renshaw, Stephen A., Whyte, Moira K. B. and Sabroe, Ian 2017. NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival. Blood 130 (8) , pp. 1014-1025. 10.1182/blood-2017-03-770164

Lopez-Anton, Melisa, Lambie, Mark, Lopez-Cabrera, Manuel, Schmitt, Claus P., Ruiz-Carpio, Vicente, Bartosova, Maria, Schaefer, Betti, Davies, Simon, Stone, Timothy, Jenkins, Robert, Taylor, Philip R., Topley, Nicholas, Bowen, Timothy and Fraser, Donald 2017. miR-21 promotes fibrogenesis in peritoneal dialysis. American Journal of Pathology 187 (7) , pp. 1537-1550. 10.1016/j.ajpath.2017.03.007

Liao, Chia-Te, Andrews, Robert, Wallace, Leah E., Khan, Mohd Wajid A., Kift-Morgan, Ann, Topley, Nicholas, Fraser, Donald J. and Taylor, Philip R. 2017. Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes. Kidney International 91 (5) , pp. 1088-1103. 10.1016/j.kint.2016.10.030

Lauder, Sarah N., Tyrrell, Victoria J., Allen-Redpath, Keith, Aldrovandi, MacEler, Gray, David, Collins, Peter, Jones, Simon A., Taylor, Philip R. and O'Donnell, Valerie 2017. Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo. Wellcome Open Research 2 (1) 10.12688/wellcomeopenres.10308.1

Perks, William V., Singh, Ravinder K., Jones, Gareth W., Twohig, Jason P., Williams, Anwen S., Humphreys, Ian R., Taylor, Philip R., Jones, Simon A. and Wang, Eddie C. Y. 2016. Death Receptor 3 promotes chemokine directed leukocyte recruitment in acute resolving inflammation and is essential for pathological development of mesothelial fibrosis in chronic disease. American Journal of Pathology 186 (11) , pp. 2813-2823. 10.1016/j.ajpath.2016.07.021

Liao, Chia-Te, Rosas, Marcela, Davies, Luke C., Giles, Peter J., Tyrrell, Victoria J., O'Donnell, Valerie B., Topley, Nicholas, Humphreys, Ian R., Fraser, Donald J., Jones, Simon A. and Taylor, Philip R. 2016. IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation. European Journal of Immunology 46 (9) , pp. 2222-2232. 10.1002/eji.201646528

Patin, Emmanuel, Jones, Adam V., Thompson, Aiysha, Clement, Mathew, Liao, Chia-Te, Griffiths, James S., Wallace, Leah, Bryant, Clare E., Lang, Roland, Rosenstiel, Philip, Humphreys, Ian R., Taylor, Philip Russel, Jones, Gareth Wyn and Orr, Selinda Jane 2016. IL-27 induced by Select Candida spp. via TLR7/NOD2 signaling and IFN-β production inhibits fungal clearance. The Journal of Immunology 197 (1) , pp. 208-221. 10.4049/jimmunol.1501204

Liao, Chia-Te, Fraser, Donald, Topley, Nicholas and Taylor, Philip 2015. Deciphering the peritoneal mononuclear phagocyte system in mice: Steady state and inflammation [Poster abstract]. Nephrology Dialysis Transplantation 30 (iii) , iii265-. 10.1093/ndt/gfv180.25

Liao, Chia-Te, Fraser, Donald J., Topley, Nicholas and Taylor, Philip Russel 2015. Determining the identity and functional specialization of peritoneal mononuclear phagocytes in peritoneal dialysis patients. Nephrology Dialysis Transplantation 30 (S3) , iii264. 10.1093/ndt/gfv180.21

Jenkins, Robert, Liao, Chia-Te, Wallace, Leah, Bowen, Timothy, Topley, Nicholas, Taylor, Philip and Fraser, Donald 2015. Microrna regulation of macrophage phenotype in peritoneal fibrosis. Nephrology Dialysis Transplantation 30 (iii262) 10.1093/ndt/gfv180.15

Davies, Luke Cynlais and Taylor, Philip Russel 2015. Tissue-resident macrophages: then and now. Immunology 144 (4) , pp. 541-548. 10.1111/imm.12451

Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone, Stanton, Richard J., Gallimore, Awen M., Hussell, Tracy, Wilkinson, Gavin W. G., Ghazal, Peter, Taylor, Philip R. and Humphreys, Ian R. 2015. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathogens 11 (2) , e1004641. 10.1371/journal.ppat.1004641

Liddiard, Kate and Taylor, Philip Russel 2015. Understanding local macrophage phenotypes in disease: shape-shifting macrophages. Nature Medicine 21 (2) , pp. 119-120. 10.1038/nm.3798

Veninga, Henrike, Borg, Ellen G. F., Vreeman, Kyle, Taylor, Philip R., Kalay, Hakan, van Kooyk, Yvette, Kraal, Georg, Martinez-Pomares, Luisa and den Haan, Joke M.M. 2015. Antigen targeting reveals splenic CD169+macrophages as promoters of germinal center B-cell responses. European Journal of Immunology 45 (3) , pp. 747-757. 10.1002/eji.201444983

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Newton, Zarabeth, Harvey, Ann K., Moideen, Abdul Nazeer, Collins, Fraser L., Bloom, Anja C., Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Rosas, Marcela, Taylor, Philip Russel, O'Neill, Luke A., Humphreys, Ian R., Williams, Anwen Sian and Jones, Simon Arnett 2014. Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction. Arthritis Research and Therapy 16 (4) , 419. 10.1186/s13075-014-0419-y

Rosas, Marcela, Davies, Luke C., Giles, Peter J., Liao, Chia-Te, Kharfan, Bashar, Stone, Timothy C., O'Donnell, Valerie B., Fraser, Donald J., Jones, Simon A. and Taylor, Philip R. 2014. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science 344 (6184) , pp. 645-648. 10.1126/science.1251414

Jenkins, Robert H., Davies, Luke C., Taylor, Philip R., Akiyama, Hideo, Cumbes, Bevan, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O., Bowen, Timothy and Fraser, Donald J. 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184 (4) , pp. 996-1009. 10.1016/j.ajpath.2013.12.028

Stacey, Maria A., Marsden, Morgan, Pham N., Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M., Taylor, Philip R., Snelgrove, Robert J., Lawley, Trevor D., Dougan, Gordon, Benedict, Chris A., Jones, Simon A., Wilkinson, Gavin W. G. and Humphreys, Ian R. 2014. Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV. Cell Host and Microbe 15 (4) , pp. 471-483. 10.1016/j.chom.2014.03.003

Fielding, Ceri A., Jones, Gareth W., McLoughlin, Rachel M., McLeod, Louise, Hammond, Victoria J., Uceda, Javier, Williams, Anwen S., Lambie, Mark, Foster, Thomas L., Liao, Chia-Te, Rice, Christopher M., Greenhill, Claire J., Colmont, Chantal S., Hams, Emily, Coles, Barbara, Kift-Morgan, Ann, Newton, Zarabeth, Craig, Katherine J., Williams, John D., Williams, Geraint T., Davies, Simon J., Humphreys, Ian R., O'Donnell, Valerie B., Taylor, Philip R., Jenkins, Brendan J., Topley, Nicholas and Jones, Simon A. 2014. Interleukin-6 signaling drives fibrosis in unresolved inflammation. Immunity 40 (1) , pp. 40-50. 10.1016/j.immuni.2013.10.022

Ling, Guang Sheng, Bennett, Jason, Woollard, Kevin J., Szajna, Marta, Fossati-Jimack, Liliane, Taylor, Philip R., Scott, Diane, Franzoso, Guido, Cook, H. Terence and Botto, Marina 2014. Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages. Nature Communications 5 , 3039. 10.1038/ncomms4039

Lauder, Sarah Nicol, Jones, Emma, Smart, Kathryn, Bloom, Anja Constanze, Williams, Anwen Sian, Hindley, James P., Ondondo, Beatrice, Taylor, Philip Russel, Clement, Mathew, Fielding, Ceri Alan, Godkin, Andrew James, Jones, Simon Arnett and Gallimore, Awen Myfanwy 2013. Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology. European Journal of Immunology 43 (10) , pp. 2613-2625. 10.1002/eji.201243018

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Harvey, Ann, Moideen, Abdul Nazeer, Collins, Fraser, Bloom, Anja Constanze, Coll, R., Rosas, Marcela, Taylor, Philip Russel, O'Neill, L. A., Humphreys, Ian R., Williams, Anwen Sian and Jones, Simon Arnett 2013. Interleukin 10 control of the inflammasome restricts arthritic bone erosion [Abstract]. Cytokine 63 (3) , p. 267. 10.1016/j.cyto.2013.06.105

Fielding, Ceri Alan, Jones, Gareth Wyn, Taylor, Philip Russel, Jenkins, Brendan J., Topley, Nicholas and Jones, Simon Arnett 2013. IL-6 regulation of Th1 responses drives fibrosis in unresolved inflammation [Abstract]. Cytokine 63 (3) , p. 262. 10.1016/j.cyto.2013.06.082

Davies, Luke Cynlais, Rosas, Marcela, Jenkins, Stephen J., Liao, Chia-Te, Scurr, Martin John, Brombacher, Frank, Fraser, Donald James, Allen, Judith E., Jones, Simon Arnett and Taylor, Philip Russel 2013. Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation. Nature Communications 4 , 1886. 10.1038/ncomms2877

Orr, Selinda Jane, Burg, Ashley R., Chan, Tim, Quigley, Laura, Jones, Gareth Wyn, Ford, Jill W., Hodge, Deborah, Razzook, Catherine, Sarhan, Joseph, Jones, Yava L., Whittaker, Gillian C., Boelte, Kimberly C., Lyakh, Lyudmila, Cardone, Marco, O'Connor, Geraldine M., Tan, Cuiyan, Li, Hongchuan, Anderson, Stephen K., Jones, Simon Arnett, Zhang, Weiguo, Taylor, Philip Russel, Trinchieri, Giorgio and McVicar, Daniel W. 2013. LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells. PLoS Pathogens 9 (5) , e1003357. 10.1371/journal.ppat.1003357

Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip Russel, Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence and Kroemer, Guido 2013. Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. Immunity 38 (4) , pp. 729-741. 10.1016/j.immuni.2013.03.003

Kuwana, M, Fossati-Jimack, L, Ling, G, Cortini, A, Szajna, M, Malik, T, McDonald, Jacqueline, Pickering, M, Cook, H, Taylor, Philip and Botto, M 2013. Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells. PLoS ONE 8 (2) , e57082. 10.1371/journal.pone.0057082

Davies, Luke Cynlais, Jenkins, S., Allen, J. and Taylor, Philip Russel 2013. Tissue-resident macrophages [review]. Nature Immunology 14 (10) , pp. 986-995. 10.1038/ni.2705

Karsten, Christian M., Pandey, Manoj K., Figge, Julia, Kilchenstein, Regina, Taylor, Philip Russel, Rosas, Marcela, McDonald, Jacqueline U., Orr, Selinda Jane, Berger, Markus, Petzold, Dominique, Blanchard, Veroniqué, Winkler, André, Hess, Constanze, Reid, Delyth M., Majoul, Irina V., Strait, Richard T., Harris, Nathaniel L., Köhl, Gabriele, Wex, Eva, Ludwig, Ralf, Zillikens, Detlef, Nimmerjahn, Falk, Finkelman, Fred D., Brown, Gordon D., Ehlers, Marc and Köhl, Jörg 2012. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1 [Letter]. Nature Medicine 18 (9) , pp. 1401-1406. 10.1038/nm.2862

McDonald, Jacqueline U., Rosas, Marcela, Brown, Gordon D., Jones, Simon Arnett and Taylor, Philip Russel 2012. Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation. PLoS ONE 7 (9) , e45781. 10.1371/journal.pone.0045781

Greenhill, Claire J., Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela, Taylor, Philip Russel, Humphreys, Ian R., Williams, Anwen Sian and Jones, Simon Arnett 2012. Cross-talk between IL-10 and the inflammasome regulates bone erosions during rheumatoid arthritis [Abstract]. Immunology 137 , pp. 43-44.

Taylor, Philip Russel, Heydeck, Dagmar, Jones, Gareth Wyn, Kronke, Gerhard, Funk, Colin D., Knapper, Steven, Adams, Deborah, Kuhn, Hartmut and O'Donnell, Valerie Bridget 2012. Development of myeloproliferative disease in 12/15-lipoxygenase deficiency [Letter]. Blood 119 (25) , pp. 6173-6174. 10.1182/blood-2012-02-410928

Greenhill, Claire, Williams, Anwen Sian, Jones, Gareth Wyn, Nowell, Mari Ann, Moideen, Abdul Nazeer, Rosas, Marcela, Taylor, Philip Russel, Humphreys, Ian R. and Jones, Simon Arnett 2012. The regulation of arthritic bone erosions by il-10 [Abstract]. Rhuematology 51 , p. 48. 10.1093/rheumatology/kes117

Greenhill, Claire J., Williams, Anwen Sian, Jones, Gareth Wyn, Nowell, Mari Ann, Rosas, Marcela, Taylor, Philip Russel, Humphreys, Ian R. and Jones, Simon Arnett 2011. The regulation of arthritic bone erosions by IL-10 [Abstract]. Immunology 135 (s1) , p. 158. 10.1111/j.1365-2567.2011.03534.x

McDonald, Jacqueline U., Cortini, Andrea, Rosas, Marcela, Fossati-Jimack, Liliane, Ling, Guang Sheng, Lewis, Kimberley, Dewitt, Sharon, Liddiard, Kate, Brown, Gordon D., Jones, Simon Arnett, Hallett, Maurice Bartlett, Botto, Marina and Taylor, Philip Russel 2011. In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils. The FASEB Journal 25 (6) , pp. 1972-1982. 10.1096/fj.10-178517

Lauder, Sarah Nicol, Taylor, Philip Russel, Clark, Stephen Robert, Evans, Rhys Lloyd, Hindley, James Phillip, Smart, Kathryn, Leach, Heather, Kidd, Emma Jane, Broadley, Kenneth John, Jones, Simon Arnett, Wise, Matthew Peter, Godkin, Andrew James, O'Donnell, Valerie Bridget and Gallimore, Awen Myfanwy 2011. Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity. Thorax 66 (5) , pp. 368-374. 10.1136/thx.2010.150318

Rosas, Marcela, Osario, Fabiola, Robinson, Matthew J., Davies, Luke Cynlais, Dierkes, Nicola, Jones, Simon Arnett, Reis e Sousa, Caetano and Taylor, Philip Russel 2011. Hoxb8 conditionally immortalised macrophage lines model inflammatory monocytic cells with important similarity to dendritic cells. European Journal of Immunology 41 (2) , pp. 356-365. 10.1002/eji.201040962

Liddiard, Kate, Rosas, Marcela, Davies, Luke Cynlais, Jones, Simon Arnett and Taylor, Philip Russel 2011. Macrophage heterogeneity and acute inflammation. European Journal of Immunology 41 (9) , pp. 2503-2508. 10.1002/eji.201141743

Davies, Luke Cynlais, Rosas, Marcela, Smith, Paul James, Fraser, Donald James, Jones, Simon Arnett and Taylor, Philip Russel 2011. A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation. European Journal of Immunology 41 (8) , pp. 2155-2164. 10.1002/eji.201141817

da Glória Sousa, Maria, Reid, Delyth M., Schweighoffer, Edina, Tybulewicz, Victor, Ruland, Jürgen, Langhorne, Jean, Yamasaki, Sho, Taylor, Philip Russel, Almeida, Sandro R. and Brown, Gordon D. 2011. Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin. Cell Host & Microbe 9 (5) , pp. 436-443. 10.1016/j.chom.2011.04.005

Gazi, U., Rosas, Marcela, Singh, S., Heinsbroek, S., Haq, I., Johnson, S., Brown, G. D., Williams, D. L., Taylor, Philip Russel and Martinez-Pomares, L. 2011. Fungal Recognition Enhances Mannose Receptor Shedding through Dectin-1 Engagement. Journal of Biological Chemistry 286 (10) , pp. 7822-7829. 10.1074/jbc.M110.185025

Clark, Stephen Robert, Guy, Christopher J., Scurr, Martin J., Taylor, Philip Russel, Kift-Morgan, Ann Patricia, Hammond, Victoria Jayne, Thomas, Christopher P., Coles, Barbara, Roberts, Gareth Wyn, Eberl, Matthias, Jones, Simon Arnett, Topley, Nicholas, Kotecha, Sailesh and O'Donnell, Valerie Bridget 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117 (6) , pp. 2033-2043. 10.1182/blood-2010-04-278887

Boyle, Keith B., Gyori, David, Sindrilaru, Anca, Scharffetter-Kochanek, Karin, Taylor, Philip Russel, Mocsai, Attila, Stephens, Len R. and Hawkins, Phillip T. 2011. Class IA phosphoinositide 3-kinase β and δ regulate neutrophil oxidase activation in response to aspergillus fumigatus hyphae. The Journal of Immunology 186 (5) , pp. 2978-2989. 10.4049/jimmunol.1002268

Suram, S., Gangelhoff, T. A., Taylor, Philip Russel, Rosas, Marcela, Brown, G. D., Bonventre, J. V., Akira, S., Uematsu, S., Williams, D. L., Murphy, R. C. and Leslie, C. C. 2010. Pathways Regulating Cytosolic Phospholipase A2 Activation and Eicosanoid Production in Macrophages by Candida albicans. Journal of Biological Chemistry 285 (40) , pp. 30676-30685. 10.1074/jbc.M110.143800

Wang, Jinyong, Liu, Yangang, Li, Zeyang, Du, Juan, Ryu, Myung-Jeom, Taylor, Philip Russel, Fleming, Mark D., Young, Ken H., Pitot, Henry and Zhang, Jing 2010. Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia. Blood 116 (26) , pp. 5991-6002. 10.1182/blood-2010-04-281527

Rosas, Marcela, Thomas, Benjamin, Stacey, Martin, Gordon, Siamon and Taylor, Philip Russel 2010. The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. Journal of leukocyte biology 88 (1) , pp. 169-180. 10.1189/jlb.0809548

Jones, Hannah E., Taylor, Philip Russel, McGreal, Eamon Patrick, Zamze, Susanne and Wong, Simon Y. C. 2009. The contribution of naturally occurring IgM antibodies, IgM cross-reactivity and complement dependency in murine humoral responses to pneumococcal capsular polysaccharides. Vaccine 27 (42) , pp. 5806-5815. 10.1016/j.vaccine.2009.07.063

Robinson, Matthew J., Osorio, Fabiola, Rosas, Marcela, Freitas, Rui P., Schweighoffer, Edina, Gross, Olaf, Verbeek, J. Spief, Ruland, Jurgen, Tybulewicz, Victor, Brown, Gordon D., Moita, Luis Fereirra, Taylor, Philip Russel and Reis e Sousa, Caetano 2009. Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. Journal of Experimental Medicine 206 (9) , pp. 2037-2051. 10.1084/jem.20082818

Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P., Clark, Stephen Robert, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel, Jones, Simon Arnett and O'Donnell, Valerie Bridget 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284 (32) , pp. 21185-21191. 10.1074/jbc.M109.021634

Tsoni, S. Vicky, Kerrigan, Ann M., Marakalala, Mohlopheni J., Srinivasan, Naren, Duffield, Maureen, Taylor, Philip Russel, Botto, Marina, Steele, Chad and Brown, Gordon D. 2009. Complement C3 plays an essential role in the control of opportunistic fungal infections. Infection and Immunity 77 (9) , pp. 3679-3685. 10.1128/IAI.00233-09

Parti, Rajinder P., Loper, Robyn, Brown, Gordon D., Gordon, Siamon, Taylor, Philip Russel, Bonventre, Joseph V., Murphy, Robert C., Williams, David L. and Leslie, Christina C. 2009. Cytosolic phospholipase A2 activation by candida albicans in alveolar macrophages: role of dectin-1. American Journal of Respiratory Cell and Molecular Biology 42 (4) , pp. 415-423. 10.1165/rcmb.2009-0110OC

Kerrigan, Ann M., Dennehy, Kevin M., Mourao-Sa, Diego, Faro-Trindade, Inês, Willment, Janet A., Taylor, Philip Russel, Eble, Johannes A., Reis e Sousa, Caetano and Brown, Gordon D. 2009. CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils. The Journal of Immunology 182 (7) , pp. 4150-4157. 10.4049/jimmunol.0802808

Heinsbroek, Sigrid E. M., Taylor, Philip Russel, Martinez, Fernando O., Martinez-Pomares, Luisa, Brown, Gordon D. and Gordon, Siamon 2008. Stage-specific sampling by pattern recognition receptors during candida albicans phagocytosis. PLoS Pathogens 4 (11) , e1000218. 10.1371/journal.ppat.1000218

Rosas, Marcela, Liddiard, Kate, Kimberg, Matti, Faro-Trindade, Ines, McDonald, Jacqueline U., Williams, David L., Brown, Gordon D. and Taylor, Philip Russel 2008. The induction of inflammation by dectin-1 in vivo is dependent on myeloid cell programming and the progression of phagocytosis. Journal of Immunology 181 (5) , pp. 3549-3557.

Hams, Emily, Colmont, Chantal Sophie, Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2008. Oncostatin M receptor-β signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180.

Hams, Emily, Colmont, Chantal S., Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2008. Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180.

Dennehy, Kevin M., Ferwerda, Gerben, Faro-Trindade, Inês, Pyz, Elwira, Willment, Janet A., Taylor, Philip Russel, Kerrigan, Ann, Tsoni, S. Vicky, Gordon, Siamon, Meyer-Wentrup, Friederike, Adema, Gosse J., Kullberg, Bart-Jan, Schweighoffer, Edina, Tybulewicz, Victor, Mora-Montes, Hector M., Gow, Neil A. R., Williams, David L., Netea, Mihai G. and Brown, Gordon D. 2008. Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. European Journal of Immunology 38 (2) , pp. 500-506. 10.1002/eji.200737741

Dioszeghy, Vincent, Rosas, Marcela, Maskrey, Benjamin H., Colmont, Chantal Sophie, Topley, Nicholas, Chaitidis, Pavlos, Kühn, Hartmut, Jones, Simon Arnett, Taylor, Philip Russel and O'Donnell, Valerie Bridget 2008. 12/15-lipoxygenase regulates the inflammatory response to bacterial products in vivo. The Journal of Immunology 181 (9) , pp. 6514-6524.

Pyz, Elwira, Huysamen, Cristal, Marshall, Andrew S. J., Gordon, Siamon, Taylor, Philip Russel and Brown, Gordon D. 2008. Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand. European Journal of Immunology 38 (4) , pp. 1157-1163. 10.1002/eji.200738057

Saunders, Sean P., Walsh, Caitriona M., Barlow, Jillian L., Mangan, Niamh E., Taylor, Philip Russel, McKenzie, Andrew N. J., Smith, Philip and Fallon, Padraic G. 2008. The C-type lectin SIGNR1 binds schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection. Infection and Immunity 77 (1) , pp. 399-404. 10.1128/IAI.00762-08

Hams, Emily, Dioszechy, Vincent, Colmont, Chantal Sophie, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2007. Oncostatin M receptor signalling regulates monocytic cell trafficking during acute inflammation [Abstract]. Cytokine 39 (1) , p. 14. 10.1016/j.cyto.2007.07.053

Taylor, Philip Russel, Tsoni, S. Vicky, Willment, Janet A., Dennehy, Kevin M., Rosas, Marcela, Findon, Helen, Haynes, Ken, Steele, Chad, Botto, Marina, Gordon, Siamon and Brown, Gordon D. 2007. Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nature Immunology 8 (1) , pp. 31-38. 10.1038/ni1408

McGreal, Eamon Patrick, Rosas, Marcela, Brown, Gordon D., Zamze, Susanne, Wong, Simon Y.C., Gordon, Siamon, Martinez-Pomares, Luisa and Taylor, Philip Russel 2006. The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose. Glycobiology 16 (5) , pp. 422-30. 10.1093/glycob/cwj077

Taylor, Philip Russel, Brown, Gordon D., Herre, Jurgen, Williams, David L., Willment, Janet A. and Gordon, Siamon 2004. The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages. The Journal of Immunology 172 (2) , pp. 1157-1162.

Williams, D. L., Rice, R., Herre, J., Willment, J. A., Taylor, Philip Russel, Gordon, P. R. and Brown, G. D. 2003. Recognition of fungal glucans by pattern recognition receptors. In: Pandalai, S. G. ed. Recent Developments in Carbohydrate Research, Vol. 1. Trivandum: Transworld Research Network, pp. 49-66.

Taylor, Philip Russel, Brown, Gordon D., Reid, Delyth M., Willment, Janet A., Gordon, Siamon, Martinez-Pomares, Luisa and Wong, Simon Y. C. 2002. The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. Journal of Immunology 169 (7) , pp. 3876-3882.

Brown, Gordon D., Taylor, Philip Russel, Reid, Delyth M., Willment, Janet A., Williams, David L., Martinez-Pomares, Luisa, Wong, Simon Y. C. and Gordon, Siamon 2002. Dectin-1 is a major beta-glucan receptor on macrophages. Journal of Experimental Medicine 196 (3) , pp. 407-12. 10.1084/jem.20020470