Kadri, Hachemi, Taher, Taher E., Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T., Willcox, Benjamin E. and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2020. Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of Vγ9/Vδ2 T-Cell immune responses. Journal of Medicinal Chemistry 63 (19) , pp. 11258-11270. 10.1021/acs.jmedchem.0c01232 |
Miccoli, Ageo, Dhiani, Binar A., Thornton, Peter J., Lambourne, Olivia A., James, Edward, Kadri, Hachemi and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2020. Aryloxy triester phosphoramidates as phosphoserine prodrugs: a proof of concept study. ChemMedChem 15 (8) , pp. 671-674. 10.1002/cmdc.202000034 |
AlAmri, Mubarak A, Kadri, Hachemi, Jeeves, Mark, Alderwick, Luke J and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2018. The photosensitizing clinical agent verteporfin is an inhibitor of SPAK and OSR1 kinases. ChemBioChem 19 (19) , pp. 2072-2080. 10.1002/cbic.201800272 |
Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513, Alamri, Mubarak A., Dhiani, Binar A. and Kadri, Hachemi 2018. C -terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25. Biochemical and Biophysical Research Communications 503 (3) , pp. 1868-1873. 10.1016/j.bbrc.2018.07.128 |
Kadri, Hachemi, Lambourne, Olivia A and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2018. Niclosamide, a drug with many (re)purposes. ChemMedChem 13 (11) , pp. 1088-1091. 10.1002/cmdc.201800100 |
Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholand, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D, Burness, Kerry, Blow, Julian J, Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 and Muqit, Miratul 2018. The anthelmintic drug niclosamide and its analogues activate the Parkinson's Disease associated protein kinase PINK1. Chembiochem 19 (5) , pp. 425-429. 10.1002/cbic.201700500 |
Salim, Mahboob, Knowles, Timothy J., Baker, Alfie T., Davey, Martin S., Jeeves, Mark, Sridhar, Pooja, Wilkie, John, Willcox, Carrie R., Kadri, Hachemi, Taher, Taher E, Vantourout, Pierre, Hayday, Adrian, Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513, Mohammed, Fiyaz and Willcox, Benjamin E. 2017. BTN3A1 discriminates γδ T cell phosphoantigens from non-antigenic small molecules via a conformational sensor in its B30.2 domain. ACS Chemical Biology 12 (10) , pp. 2631-2643. 10.1021/acschembio.7b00694 |
AlAmri, Mubarak A., Kadri, Hachemi, Dhiani, Binar Asrining, Mahmood, Shumail, Elzwawi, Abdulrahman and Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 2017. WNK-signaling inhibitors as potential new antihypertensive drugs. Chemmedchem 10.1002/cmdc.201700425 |