Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Ranieri, Marianna, Lopez-Fernandez, Irene, Webberley, Thomas S., Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L., Graca, Joao, Hanif, Umar-Khetaab, Müller, Christian, Manhardt, Teresa, Salzmann, Martina, Quasnichka, Helen, Price, Sally A., Ward, Donald T., Gilbert, Thierry, Matchkov, Vladimir V., Fenton, Robert A., Herberger, Amanda, Hwong, Jenna, Santa Maria, Christian, Tu, Chia-Ling, Kallay, Enikö, Valenti, Giovanna, Chang, Wenhan and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2022. Impaired mineral ion metabolism in a mouse model of targeted calcium-sensing receptor (CaSR) deletion from vascular smooth muscle cells. Journal of the American Society of Nephrology 33 (7) , pp. 1323-1340. 10.1681/ASN.2021040585 |
Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella 2021. Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin. European Journal of Medicinal Chemistry 226 , 113841. 10.1016/j.ejmech.2021.113841 |
Yarova, Polina L., Huang, Ping, Schepelmann, Martin W. ORCID: https://orcid.org/0000-0002-7017-5426, Bruce, Richard, Ecker, Rupert, Nica, Robert, Telezhkin, Vsevolod S. ORCID: https://orcid.org/0000-0002-5054-8774, Traini, Daniela, Gomes dos Reis, Larissa, Kidd, Emma J. ORCID: https://orcid.org/0000-0001-5507-1170, Ford, William R. ORCID: https://orcid.org/0000-0002-8792-6169, Broadley, Kenneth J., Kariuki, Benson M., Corrigan, Christopher J., Ward, Jeremy P. T., Kemp, Paul J. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2021. Characterisation of negative allosteric modulators of the calcium-sensing receptor, CaSR, for repurposing as a treatment for asthma. Journal of Pharmacology and Experimental Therapeutics 376 (1) , pp. 51-63. 10.1124/jpet.120.000281 |
Pasqualetto, Gaia, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Varricchio, Carmine ORCID: https://orcid.org/0000-0002-1673-4768, Pileggi, Elisa, Khogali, Caroline, Morgan, Siân R., Boostrom, Ian, Rozanowska, Malgorzata ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2020. Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins. Molecules 25 (21) , 4904. 10.3390/molecules25214904 |
Scott Roberts, Mary, Gafni, Rachel I, Brillante, Beth, Guthrie, Lori C, Streit, Jamie, Gash, David, Gelb, Jeff, Krusinska, Eva, Brennan, Sarah C ORCID: https://orcid.org/0000-0002-8719-4367, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163, Ezuan Bin Khayat, Mohd, Ward, Donald T, Nemeth, Edward F, Rosskamp, Ralf and Collins, Michael T 2019. Treatment of autosomal dominant hypocalcemia Type 1 with the calcilytic NPSP795 (SHP635). Journal of Bone and Mineral Research 34 (9) , pp. 1609-1618. 10.1002/jbmr.3747 |
Pasqualetto, Gaia, Pileggi, Elisa, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Heard, Charles ORCID: https://orcid.org/0000-0001-9703-9777, Young, Mark Thomas ORCID: https://orcid.org/0000-0002-9615-9002, Rozanowska, Malgorzata B. ORCID: https://orcid.org/0000-0003-2913-8954, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 and Bassetto, Marcella 2019. Novel small-molecule chaperones to overcome opsin misfolding, mistrafficking and aggregation in retinal blinding diseases. Presented at: 2019 ARVO Annual Meeting, Vancouver, Canada, 28 April - 02 May 2019. Investigative ophthalmology & visual science. , vol.60 (9) ARVO, |
Graca, Joao, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C., Reens, Jaimini, Chang, Wenhan, Yan, Paul, Toka, Hakan, Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 and Price, Sally A. 2016. Comparative expression of the extracellular calcium sensing receptor in rat, mouse and human kidney. American Journal of Physiology-Renal Physiology 310 (6) , F518-F533. 10.1152/ajprenal.00208.2015 |
Schepelmann, M. ORCID: https://orcid.org/0000-0002-7017-5426, Yarova, P. L., Lopez-Fernandez, I., Davies, T. S., Brennan, S. C. ORCID: https://orcid.org/0000-0002-8719-4367, Edwards, P. J., Aggarwal, A., Graca, J., Rietdorf, K., Matchkov, V., Fenton, R. A., Chang, W., Krssak, M., Stewart, A., Broadley, K. J. ORCID: https://orcid.org/0000-0002-3339-2050, Ward, D. T., Price, S. A., Edwards, D. H., Kemp, P. J. ORCID: https://orcid.org/0000-0003-2773-973X and Riccardi, D. ORCID: https://orcid.org/0000-0002-7322-3163 2016. The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure. American Journal of Physiology - Cell Physiology 310 (3) , C193-C204. 10.1152/ajpcell.00248.2015 |
Lopez-Fernandez, Irene, Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426, Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Yarova, Polina L. and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2015. The calcium-sensing receptor: one of a kind. Experimental Physiology 100 (12) , pp. 1392-1399. 10.1113/EP085137 |
Brennan, Sarah C. ORCID: https://orcid.org/0000-0002-8719-4367, Davies, Thomas S., Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426 and Riccardi, Daniela ORCID: https://orcid.org/0000-0002-7322-3163 2014. Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion. British Journal of Nutrition 111 (S1) , S16-S22. 10.1017/S0007114513002250 |
Schepelmann, Martin ORCID: https://orcid.org/0000-0002-7017-5426
2014.
Determining the role of the calcium sensing receptor in vascular smooth muscle cells via targeted gene deletion.
PhD Thesis,
Cardiff University.
Item availability restricted. |