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Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara, Ager, Ann, Parker, Alan L., Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie, Svane, Inge Marie, Phillips, John D. and Sewell, Andrew K. 2020. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21 , 178 - 185. 10.1038/s41590-019-0578-8 |
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Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K. and Sewell, Andrew K.
2019.
TCR-induced alteration of primary MHC peptide anchor residue.
European Journal of Immunology
49
(7)
, pp. 1052-1066.
10.1002/eji.201948085
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Sewell, Andrew K. and Legut, Mateusz 2018. Designer T-cells and T-cell receptors for customised cancer immunotherapies. Current Opinion in Pharmacology 41 , pp. 96-103. 10.1016/j.coph.2018.05.005 |
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Zhao, Xiang, Sankaran, Shvetha, Yap, Jiawei, Too, Chien Tei, Ho, Zi Zong, Dolton, Garry, Legut, Mateusz, Ren, Ee Chee, Sewell, Andrew K., Bertoletti, Antonio, MacAry, Paul A., Brzostek, Joanna and Gascoigne, Nicholas R. J. 2018. Nonstimulatory peptide?MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nature Communications 9 , 2716. 10.1038/s41467-018-05288-0 |
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Legut, Mateusz, Dolton, Garry, Mian, Afsar, Ottmann, Oliver and Sewell, Andrew 2018. CRISPR-mediated TCR replacement generates superior anticancer transgenic T-cells. Blood 131 (3) , pp. 311-322. 10.1182/blood-2017-05-787598 |
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Maciocia, Paul M., Wawrzyniecka, Patrycja A., Philip, Brian, Ricciardelli, Ida, Akarca, Ayse U., Onuoha, Shimobi C., Legut, Mateusz, Cole, David K., Sewell, Andrew K., Gritti, Giuseppe, Somja, Joan, Piris, Miguel A., Peggs, Karl S., Linch, David C., Marafioti, Teresa and Pule, Martin A. 2017. Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies. Nature Medicine 23 , pp. 1416-1423. 10.1038/nm.4444 |
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Cole, David K., Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad, Evavold, Brian D., Rizkallah, Pierre J. and Sewell, Andrew K.
2017.
Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope.
Frontiers in Immunology
8
, 1503.
10.3389/fimmu.2017.01503
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Donia, Marco, Kjeldsen, Julie Westerlin, Andersen, Rikke, Wulff Westergaard, Marie Christine, Bianchi, Valentina, Legut, Mateusz, Attaf, Meriem, Szomolay, Barbara, Ott, Sascha, Dolton, Garry, Lyngaa, Rikke, Hadrup, Sine Reker, Sewell, Andrew K. and Svane, Inge Marie
2017.
PD-1+ polyfunctional T cells dominate the periphery after tumour-infiltrating lymphocyte therapy for cancer.
Clinical Cancer Research
23
(19)
, pp. 5779-5788.
10.1158/1078-0432.CCR-16-1692
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Legut, Mateusz
2017.
Genome editing approaches for development of pan-population immunotherapies.
PhD Thesis,
Cardiff Univeristy.
Item availability restricted. |
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Attaf, Meriem, Legut, Mateusz, Cole, David and Sewell, Andrew K. 2015. The T cell antigen receptor: the Swiss army knife of the immune. Clinical and Experimental Immunology 181 (1) , pp. 1-18. 10.1111/cei.12622 |
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Uusi-Kerttula, Hanni, Legut, Mateusz, Davies, James Anthony, Jones, Rachel, Hudson, Emma, Hanna, Louise, Stanton, Richard James, Chester, John D. and Parker, Alan L. 2015. Incorporation of peptides targeting EGFR and FGFR1 into the adenoviral fibre knob domain, and their evaluation as targeted cancer therapies. Human Gene Therapy 26 (5) , pp. 320-329. 10.1089/hum.2015.015 |
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Legut, Mateusz, Cole, David and Sewell, Andrew K. 2015. The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy. Cellular and Molecular Immunology 12 , pp. 656-668. 10.1038/cmi.2015.28 |
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