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Number of items: 81.

Crawford, Greg, Hayes, Mark David, Seoane, Rocio Castro, Ward, Sophie, Dalessandri, Tim, Lai, Chester, Healy, Eugene, Kipling, David, Proby, Charlotte, Moyes, Colin, Green, Kile, Best, Katie, Haniffa, Muzlifah, Botto, Marina, Dunn-Walters, Deborah and Strid, Jessica 2018. Epithelial damage and tissue T cells promote a unique tumor-protective IgE response. Nature Immunology 19 (8) , pp. 859-870. 10.1038/s41590-018-0161-8
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Caley, Matthew, Wall, Ivan, Peake, Matthew, Kipling, David, Giles, Peter, Thomas, David and Stephens, Phil 2018. Development and characterisation of a human chronic skin wound cell line - towards an alternative for animal experimentation. International Journal of Molecular Sciences 19 (4) , 1001. 10.3390/ijms19041001
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Sáez de Guinoa, Julia, Jimeno, Rebeca, Gaya, Mauro, Kipling, David, Garzón, María José, Dunn-Walters, Deborah, Ubeda, Carles and Barral, Patricia 2018. CD1d‐mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis. EMBO Journal 37 (5) , e97537. 10.15252/embj.201797537
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Björkman, Andrea, Du, Likun, van der Burg, Mirjam, Cormier-Daire, Valerie, Borck, Guntram, Pié, Juan, Anderlid, Britt-Marie, Hammarström, Lennart, Ström, Lena, de Villartay, Jean-Pierre, Kipling, David, Walters, Deborah Dunn and Pan-Hammarström, Qiang 2018. Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome. Journal of Allergy and Clinical Immunology 141 (1) , pp. 408-411. 10.1016/j.jaci.2017.06.043
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Alimbetov, Dauren, Askarova, Sholpan, Umbayev, Bauyrzhan, Davis, Terence and Kipling, David 2018. Pharmacological Targeting of Cell Cycle, Apoptotic and Cell Adhesion Signaling Pathways Implicated in Chemoresistance of Cancer Cells. International Journal of Molecular Sciences 19 (6) , p. 1690. 10.3390/ijms19061690
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Martin, Victoria G., Wu, Yu-Chang Bryan, Townsend, Catherine L., Lu, Grace H. C., O'Hare, Joselli Silva, Mozeika, Alexander, Coolen, Anthonius C. C., Kipling, David, Fraternali, Franca and Dunn-Walters, Deborah K. 2016. Transitional B cells in early human B cell development - time to revisit the paradigm? Frontiers in Immunology 7 , 546. 10.3389/fimmu.2016.00546
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Townsend, Catherine L., Laffy, Julie M. J., Wu, Yu-Chang Bryan, Silva O'Hare, Joselli, Martin, Victoria, Kipling, David Glyn, Fraternali, Franca and Dunn-Walters, Deborah K. 2016. Significant differences in physicochemical properties of human immunoglobulin kappa and lambda CDR3 regions. Frontiers in Immunology 7 10.3389/fimmu.2016.00388
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Davis, Terence, Brook, Amy Jayne Chedzoy, Rokicki, Michal Jaroslaw, Bagley, Mark and Kipling, David Glyn 2016. Evaluating the role of p38 MAPK in the accelerated cell senescence of Werner syndrome fibroblasts. Pharmaceuticals 9 (2) , 23. 10.3390/ph9020023
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Bagley, Mark C., Dwyer, Jessica E., Baashen, Mohammed, Dix, Matthew C., Murziani, Paola G. S., Rokicki, Michal J., Kipling, David Glyn and Davis, Terence 2016. The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells. Organic & Biomolecular Chemistry 14 (3) , pp. 947-956. 10.1039/C5OB02229K
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Martin, Victoria, Wu, Yu-Chang, Kipling, David Glyn and Dunn-Walters, Deborah K. 2015. Age-related aspects of human IgM+ B cell heterogeneity. Annals of the New York Academy of Sciences 1362 , pp. 153-163. 10.1111/nyas.12823
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Alimbetov, Dauren, Davis, Terence, Brook, Amy J. C., Cox, Lynne S., Faragher, Richard G. A., Nurgozhin, Talgat, Zhumadilov, Zhaxybay and Kipling, David Glyn 2015. Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2. Biogerontology , pp. 1-11. 10.1007/s10522-015-9610-z
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Martin, Victoria, (Bryan) Wu, Yu-Chang, Kipling, David and Dunn-Walters, Deborah 2015. Ageing of the B-cell repertoire. Philosophical Transactions of the Royal Society B: Biological Sciences 370 (1676) , p. 20140237. 10.1098/rstb.2014.0237

Bagley, Mark, Baashen, Mohammed, Chuckowree, Irina, Dwyer, Jessica, Kipling, David Glyn and Davis, Terence 2015. Microwave-assisted synthesis of a MK2 inhibitor by Suzuki-Miyaura coupling for study in Werner Syndrome Cells. Pharmaceuticals 8 (2) , pp. 257-276. 10.3390/ph8020257
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Hehle, Verena, Fraser, Louise D., Tahir, Romeeza, Kipling, David, Wu, Yu-Chang, Lutalo, Pamela M.K., Cason, John, Choong, LeeMeng, D'Cruz, David P., Cope, Andrew P., Dunn-Walters, Deborah K. and Spencer, Jo 2015. Immunoglobulin kappa variable region gene selection during early human B cell development in health and systemic lupus erythematosus. Molecular Immunology 65 (2) , pp. 215-223. 10.1016/j.molimm.2015.01.017

Tete, Sarah M., Kipling, David Glyn, Westra, Johanna, de Haan, Aalzen, Bijl, Marc, Dunn-Walters, Deborah K., Sahota, Surinder S. and Bos, Nicolaas A. 2015. Monoclonal paraprotein influences baseline B-cell repertoire diversity and perturbates influenza vaccination-induced B-cell response. Experimental Hematology 43 (6) , pp. 439-447. 10.1016/j.exphem.2015.02.005

Davis, Terence, Tivey, Hannah S.E., Brook, Amy J.C. and Kipling, David 2015. Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBNp70 protein undergo p38/MK2-dependent premature senescence. Biogerontology 16 (1) , pp. 43-51. 10.1007/s10522-014-9530-3
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Wu, Yu-Chang, Kipling, David and Dunn-Walters, Deborah 2015. Assessment of B Cell Repertoire in Humans. Methods in Molecular Biology 1343 , pp. 199-218. 10.1007/978-1-4939-2963-4_16

Wu, Yu-Chang B., James, Louisa K., Vander Heiden, Jason A., Uduman, Mohamed, Durham, Stephen R., Kleinstein, Steven H., Kipling, David and Gould, Hannah J. 2014. Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis. Journal of Allergy and Clinical Immunology 134 (3) , pp. 604-612. 10.1016/j.jaci.2014.07.010
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Sabouri, Zahra, Schofield, Peter, Horikawa, Keisuke, Spierings, Emily, Kipling, David Glyn, Randall, Katrina L., Langley, David, Roome, Brendan, Vazquez-Lombardi, Rodrigo, Rouet, Romain, Hermes, Jana, Chan, Tyani D., Brink, Robert, Dunn-Walters, Deborah K., Christ, Daniel and Goodnow, Christopher C. 2014. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. Proceedings of the National Academy of Sciences of the United States of America 111 (25) , E2567-E2575. 10.1073/pnas.1406974111
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Peake, Matthew A., Caley, Mathew, Giles, Peter J., Wall, Ivan B., Enoch, Stuart, Davies, Lindsay Catrina, Kipling, David Glyn, Thomas, David William and Stephens, Philip 2014. Identification of a transcriptional signature for the wound healing continuum. Wound Repair and Regeneration 22 (3) , pp. 399-405. 10.1111/wrr.12170
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Broccoli, D, Shaker, M, Pascarelli, K, Plantinga, M, Love, M, Lazar, A, Ingram, R, von Mehren, M, Lev, D and Kipling, David Glyn 2014. Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas. Biomarkers in Cancer 6 , pp. 1-10. 10.4137/BIC.S14683

Mark, Bagley, Mohammed, Baashen, Jessica, Dwyer, Pierre, Milbeo, Kipling, David Glyn and Davis, Terence 2014. Microwave-assisted Synthesis of Inhibitors of MK2 for Targeting p38 MAP Kinase Signalling in Werner Syndrome Cells. In: John, Spencer and Mark, Bagley eds. Microwaves in Drug Discovery and Development: Recent Advances, London: Future Medicine Ltd, pp. 86-104. (10.4155/fseb2013.13.130)

Bagley, Mark C., Baashen, Mohammed, Paddock, Victoria L., Kipling, David Glyn and Davis, Terence 2013. Regiocontrolled synthesis of 3- and 5-aminopyrazoles, pyrazolo[3,4-d]pyrimidines, pyrazolo[3,4-b]pyridines and pyrazolo[3,4-b]quinolinones as MAPK inhibitors. Tetrahedron 69 (39) , pp. 8429-8438. 10.1016/j.tet.2013.07.055

de Miranda, Noel F. C. C., Peng, Roujun, Georgiou, Konstantinos, Wu, Chenglin, Sorqvist, Elin Falk, Berglund, Mattias, Chen, Longyun, Gao, Zhibo, Lagerstedt, Kristina, Lisboa, Susana, Roos, Fredrik, van Wezel, Tom, Teixeira, Manuel R., Rosenquist, Richard, Sundstrom, Christer, Enblad, Gunilla, Nilsson, Mats, Zeng, Yixin, Kipling, David Glyn and Pan-Hammarstrom, Qiang 2013. DNA repair genes are selectively mutated in diffuse large B cell lymphomas. Journal of Experimental Medicine 210 (9) , pp. 1729-1742. 10.1084/jem.20122842
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Kenessary, Almas, Zhumadilov, Zhaxybay, Nurgozhin, Talgat, Kipling, David Glyn, Yeoman, Mark, Cox, Lynne, Ostler, Elizabeth and Faragher, Richard 2013. Biomarkers, interventions and healthy ageing. New Biotechnology 30 (4) , pp. 373-377. 10.1016/j.nbt.2012.11.018

Tivey, Hannah S. E., Brook, Amy Jayne Chedzoy, Rokicki, Michal Jaroslaw, Kipling, David Glyn and Davis, Terence 2013. p38 MAPK stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes. Biogerontology 14 (1) , pp. 47-62. 10.1007/s10522-012-9407-2
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Davis, Terence, Rokicki, Michal Jaroslaw, Bagley, Mark C. and Kipling, David Glyn 2013. The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome. Chemistry Central Journal 7 , 18. 10.1186/1752-153X-7-18
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Davis, Terence, Tivey, Hannah, Brook, Amy Jayne Chedzoy, Grimstead, Julia W., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2013. Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome. AGE 35 (5) , pp. 1767-1783. 10.1007/s11357-012-9476-9
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Tivey, Hannah S. E., Rokicki, Michal Jaroslaw, Barnacle, James R., Rogers, Mathew James, Bagley, Mark C., Kipling, David Glyn and Davis, Terence 2013. Small molecule inhibition of p38 MAP kinase extends the replicative life span of human ATR-Seckel syndrome fibroblasts. The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 68 (9) , pp. 1001-1009. 10.1093/gerona/gls336
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Wu, Yu-Chang Bryan, Kipling, David Glyn and Dunn-Walters, Deborah K. 2012. Age-related changes in human peripheral blood IGH repertoire following vaccination. Frontiers in Immunology 3 , 193. 10.3389/fimmu.2012.00193
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Doyle, K. R., Mitchell, M. A., Roberts, C. L., James, S., Johnson, J. E., Zhou, Y., von Mehren, M., Lev, D., Kipling, David Glyn and Broccoli, D. 2012. Validating a gene expression signature proposed to differentiate liposarcomas that use different telomere maintenance mechanisms [Letter]. Oncogene 31 (2) , pp. 265-266. 10.1038/onc.2011.225
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Sheerin, Angela N., Smith, Susan Kaye, Jennert-Burston, Katrin, Brook, Amy Jayne Chedzoy, Allen, Marcus C., Ibrahim, Badr, Jones, Dawn, Wallis, Corrin, Engelmann, Katrin, Rhys-Williams, William, Faragher, Richard G. A. and Kipling, David Glyn 2012. Characterization of cellular senescence mechanisms in human corneal endothelial cells. Aging Cell 11 (2) , pp. 234-240. 10.1111/j.1474-9726.2011.00776.x

Ademokun, Alexander, Wu, Yu-Chang, Martin, Victoria, Mitra, Rajive, Sack, Ulrich, Baxendale, Helen, Kipling, David Glyn and Dunn-Walters, Deborah K. 2011. Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages. Aging Cell 10 (6) , pp. 922-930. 10.1111/j.1474-9726.2011.00732.x

Davis, Terence, Dix, Matthew Charles, Rokicki, Michal Jaroslaw, Brook, Amy Jayne Chedzoy, Widdowson, Caroline Susan, Kipling, David Glyn and Bagley, Mark Christopher 2011. Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors. Chemistry Central Journal 5 (1) , pp. 83-88. 10.1186/1752-153X-5-83

Bagley, Mark Christopher, Davis, Terence, Latimer, Joanna Elizabeth and Kipling, David Glyn 2011. The contribution of biogerontology to quality ageing. Quality in Ageing and Older Adults 12 (1) , pp. 26-32. 10.5042/qiaoa.2011.0142

Latimer, Joanna Elizabeth, Davis, Terence, Bagley, Mark Christopher and Kipling, David Glyn 2011. Ageing science, health care and social inclusion of older people. Quality in Ageing and Older Adults 12 (1) , pp. 11-16. 10.5042/qiaoa.2011.0140

Di Mitri, Diletta, Azevedo, Rita I., Henson, Sian M., Libri, Valentina, Riddell, Natalie E., Macaulay, Richard, Kipling, David, Soares, Maria V. D., Battistini, Luca and Akbar, Arne N. 2011. Reversible senescence in human CD4+CD45RA+CD27- memory T cells. The Journal of Immunology 187 (5) , pp. 2093-2100. 10.4049/jimmunol.1100978

Enoch, Stuart, Peake, Matthew Arnold, Wall, Ivan Bernard, Davies, Lindsay Catrina, Farrier, Jerry N., Giles, Peter James, Kipling, David Glyn, Price, Patricia Elaine, Moseley, Ryan, Thomas, David William and Stephens, Philip 2010. 'Young' oral fibroblasts are geno/phenotypically distinct. Journal of Dental Research 89 (12) , pp. 1407-1413. 10.1177/0022034510377796

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome. Future Medicinal Chemistry 2 (9) , pp. 1417-1427. 10.4155/fmc.10.217

Wu, Yu-Chang, Kipling, David Glyn, Leong, Hui Sun, Martin, Victoria, Ademokun, Alexander A. and Dunn-Walters, Debra K. 2010. High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations. Blood 116 (7) , pp. 1070-1078. 10.1182/blood-2010-03-275859

Bagley, Mark C., Davis, Terence, Murziani, Paola G. S., Widdowson, Caroline and Kipling, David Glyn 2010. Use of p38 MAPK inhibitors for the treatment of Werner Syndrome. Pharmaceuticals 3 (6) , pp. 1842-1872. 10.3390/ph3061842
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Bagley, Mark Christopher, Davis, Terence, Rokicki, Michal Jaroslaw, Widdowson, Caroline Susan and Kipling, David Glyn 2010. Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome. Future Medicinal Chemistry 2 (2) , pp. 193-201. 10.4155/fmc.09.163

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2010. Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells. Future Medicinal Chemistry 2 (2) , pp. 203-213. 10.4155/fmc.09.160

Davis, Terence, Bachler, Marcus Aurelius, Wyllie, Fiona Sandra, Bagley, Mark Christopher and Kipling, David 2010. Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts. Annals of the New York Academy of Sciences 1197 (1) , pp. 45-48. 10.1111/j.1749-6632.2010.05195.x

Mitchell, M. A., Johnson, J. E., Pascarelli, K., Beeharry, N., Chiourea, M., Gagos, S., Lev, D., von Mehren, M., Kipling, David Glyn and Broccoli, D. 2010. Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres. Molecular Cancer Therapeutics 9 (3) , pp. 682-692. 10.1158/1535-7163.MCT-09-0705

Enoch, Stuart, Wall, Ivan Bernard, Peake, Matthew Arnold, Davies, Lindsay Catrina, Farrier, Jerry N., Giles, Peter James, Baird, Duncan Martin, Kipling, David Glyn, Price, Patricia Elaine, Moseley, Ryan, Thomas, David William and Stephens, Philip 2009. Increased oral fibroblast lifespan is telomerase-independent. Journal of Dental Research 88 (10) , pp. 916-921. 10.1177/0022034509342979

Davis, Terence, Tivey, Hannah S. E. and Kipling, David 2009. Telomere dynamics and biology in human progeroid syndromes. In: Mancini, Leonardo ed. Telomeres: Function, Shortening and Lengthening, New York: Nova Science Publishers, Inc., pp. 1-75.

Davis, Terence and Kipling, David Glyn 2009. Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of Ataxia Telangiectasia and Werner syndrome fibroblasts. Biogerontology 10 (3) , pp. 253-266. 10.1007/s10522-008-9179-x
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Gibson, Kate L., Wu, Yu-Chang, Barnett, Yvonne, Duggan, Orla, Vaughan, Robert, Kondeatis, Elli, Nilsson, Bengt-Olof, Wikby, Anders, Kipling, David Glyn and Dunn-Walters, Deborah K. 2009. B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell 8 (1) , pp. 18-25. 10.1111/j.1474-9726.2008.00443.x

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Fusillo, Vincenzo, Pigeaux, Morgane, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2009. Microwave-assisted Ullmann C-S bond formation: synthesis of the P38 alpha MAPK clinical candidate VX-745. Journal of Organic Chemistry 74 (21) , pp. 8336-8342. 10.1021/jo9017155

Burton, Dominick G. A., Giles, Peter James, Sheerin, Angela N.P., Smith, Susan Kaye, Lawton, Jessica J., Ostler, Elizabeth L., Rhys-Williams, William, Kipling, David Glyn and Faragher, Richard G. A. 2009. Microarray analysis of senescent vascular smooth muscle cells: a link to atherosclerosis and vascular calcification. Experimental Gerontology 44 (10) , pp. 659-665. 10.1016/j.exger.2009.07.004

Kipling, David Glyn, Jones, Dawn L., Smith, Susan Kaye, Giles, Peter James, Jennert-Burston, Katrin, Ibrahim, Badr, Sheerin, Angela N.P., Evans, Amy J. C., Rhys-Willams, William and Faragher, Richard G.A. 2009. A transcriptomic analysis of the EK1.Br strain of human fibroblastoid keratocytes: the effects of growth, quiescence and senescence. Experimental Eye Research 88 (2) , pp. 277-285. 10.1016/j.exer.2008.11.030

Leong, Hui Sun and Kipling, David Glyn 2009. Text-based over-representation analysis of microarray gene lists with annotation bias. Nucleic Acids Research 37 (11) , e79-e79. 10.1093/nar/gkp310

Wall, Ivan Bernard, Moseley, Ryan, Baird, Duncan Martin, Kipling, David Glyn, Giles, Peter James, Laffafian, Iraj, Price, Patricia Elaine, Thomas, David William and Stephens, Philip 2008. Fibroblast dysfunction is a key factor in the non-healing of chronic venous leg ulcers. Journal of Investigative Dermatology 128 (10) , pp. 2526-2540. 10.1038/jid.2008.114

Peake, Matthew Arnold, Giles, Peter James, Wall, Ivan Bernard, Enoch, Stuart, Kipling, David Glyn, Thomas, David William and Stephens, Philip 2008. Identifying a Gene signature for the wound healing continuum [Abstract]. Wound Repair and Regeneration 16 (6) , A71. 10.1111/j.1524-475X.2008.00424.x

Duce, James A., Podvin, Sonia, Hollander, William, Kipling, David Glyn, Rosene, Douglas L. and Abraham, Carmela R. 2008. Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey. Glia 56 (1) , pp. 106-117. 10.1002/glia.20593

Bagley, Mark Christopher, Davis, Terence, Dix, M. C., Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2008. Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 18 (13) , pp. 3745-3748. 10.1016/j.bmcl.2008.05.037

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew, Rokicki, Michal Jaroslaw and Kipling, David Glyn 2007. Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. Biorganic and Medicinal Chemistry Letters 17 (18) , pp. 5107-5110. 10.1016/j.bmcl.2007.07.016

Davis, Terence, Wyllie, Fiona Sandra, Rokicki, Michal J., Bagley, Mark C. and Kipling, David Glyn 2007. The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging. Annals of the New York Academy of Sciences 1100 , pp. 455-469. 10.1196/annals.1395.051

Davis, Terence., Bagley, Mark Christopher, Dix, M. C., Murziani, Paola G. S., Rokicki, M. J., Widdowson, C. S., Zayed, J. M., Bachler, M. A. and Kipling, David Glyn 2007. Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38 alpha(MAPK) inhibitors in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 17 (24) , pp. 6832-6835. 10.1016/j.bmcl.2007.10.036

Davis, Terence and Kipling, David Glyn 2007. Werner syndrome, telomeres, and stress signaling: implications for future therapies? In: Rudolph, K. Lenhard ed. Telomeres and Telomerase in Aging, Disease, and Cancer: Molecular Mechanisms of Adult Stem Cell Ageing, Springer, pp. 285-308.

Bagley, Mark C., Davis, Terence, Dix, Matthew C., Widdowson, Caroline S. and Kipling, David Glyn 2006. Microwave-assisted synthesis of N-pyrazole ureas and the p38α inhibitor BIRB 796 for study into accelerated cell ageing. Organic & Biomolecular Chemistry 4 (22) , pp. 4158-4164. 10.1039/b611493h

Bagley, Mark Christopher, Davis, Terence, Dix, Matthew Charles, Widdowson, Caroline S. and Kipling, David Glyn 2006. Microwave-assisted synthesis of N-pyrazole ureas and the p38 inhibitor BIRB 796 for study into accelerated cell ageing. Organic & biomolecular chemistry 4 (22) , pp. 4158-4164. 10.1039/b611493h

Davis, Terence and Kipling, David Glyn 2006. Werner Syndrome as an example of inflamm-aging: Possible therapeutic opportunities for a progeroid syndrome? Rejuvenation Research 9 (3) , pp. 402-407. 10.1089/rej.2006.9.402

Davis, Terence, Haughton, Michele F., Jones, Christopher J. and Kipling, David Glyn 2006. Prevention of accelerated cell aging in the Werner syndrome. Annals of the New York Academy of Sciences 1067 (1) , pp. 243-247. 10.1196/annals.1354.031

Britt-Compton, Bethan, Rowson, Janet Maud, Locke, Matthew, Mackenzie, Ian, Kipling, David Glyn and Baird, Duncan Martin 2006. Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans. Human Molecular Genetics 15 (5) , pp. 725-733. 10.1093/hmg/ddi486

Baird, Duncan Martin, Britt-Compton, Bethan, Rowson, Janet Maud, Amso, Nazar Najib, Gregory, Linda and Kipling, David Glyn 2006. Telomere instability in the male germline. Human molecular genetics 15 (1) , pp. 45-51. 10.1093/hmg/ddi424
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Davis, Terence and Kipling, David Glyn 2005. Telomeres and telomerase biology in vertebrates: Progress towards a non-human model for replicative senescence and ageing. Biogerontology 6 (6) , pp. 371-385. 10.1007/s10522-005-4901-4

Davis, Terence, Baird, Duncan Martin, Haughton, Michele Fleur, Jones, Christopher John and Kipling, David Glyn 2005. Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor. The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences 60 (11) , pp. 1386-93.

Davis, Terence, Skinner, Julia W., Faragher, Richard G. A., Jones, Christopher J. and Kipling, David Glyn 2005. Replicative senescence in sheep fibroblasts is a p53 dependent process. Experimental Gerontology 40 (1-2) , pp. 17-26. 10.1016/j.exger.2004.09.004

Kipling, David Glyn, Davis, Terence, Ostler, Elizabeth L. and Faragher, Richard G. A. 2004. What can progeroid syndromes tell us about human aging? Science 305 (5689) , pp. 1426-1431. 10.1126/science.1102587

Baird, Duncan Martin, Davis, Terence, Rowson, Janet Maud, Jones, Christopher John and Kipling, David Glyn 2004. Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells. Human Molecular Genetics 13 (14) , pp. 1515-1524. 10.1093/hmg/ddh159
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Stephens, Philip, Grenard, Pascale Marie, Aeschlimann, Pascale Corinne, Langley, Martin Simon, Blain, Emma Jane, Errington, Rachel Jane, Kipling, David Glyn, Thomas, David William and Aeschlimann, Daniel 2004. Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses. Journal of cell science 117 (15) , pp. 3389-3403. 10.1242/jcs.01188

Baird, Duncan Martin and Kipling, David Glyn 2004. The extent and significance of telomere loss with age. Annals of the New York Academy of Sciences 1019 (1) , pp. 265-268. 10.1196/annals.1297.044

Davis, Terence, Faragher, Richard G. A., Jones, Christopher J. and Kipling, David Glyn 2004. Investigation of the signaling pathways involved in the proliferative life span barriers in Werner syndrome fibroblasts. Annals of the New York Academy of Sciences 1019 (1) , pp. 274-277. 10.1196/annals.1297.046

Preto, Ana, Singhrao, Simarjit Kaur, Haughton, Michele Fleur, Kipling, David Glyn, Wynford-Thomas, David and Jones, Christopher John 2004. Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: implications for antitelomerase therapy. Oncogene 23 (23) , pp. 4136-4145. 10.1038/sj.onc.1207564

Evans, Rebecca Jane, Wyllie, Fiona Sandra, Wynford-Thomas, David, Kipling, David Glyn and Jones, Christopher John 2003. A P53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development. Cancer Research 63 (16) , pp. 4854-4861.

Sviderskaya, Elena V., Gray-Schopfer, Vanessa C., Hill, Simon P., Smit, Nico P., Evans-Whipp, Tracy J., Bond, Jane Ann, Hill, Lucy, Bataille, Veronique, Peters, Gordon, Kipling, David Glyn, Wynford-Thomas, David and Bennett, Dorothy C. 2003. p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression. Journal of the National Cancer Institute 95 (10) , pp. 723-732. 10.1093/jnci/95.10.723

Davis, Terence, Singhrao, Simarjit Kaur, Wyllie, Fiona Sandra, Haughton, Michele Fleur, Smith, Paul James, Wiltshire, Marie, Wynford-Thomas, David, Jones, Christopher John, Faragher, Richard G. A. and Kipling, David Glyn 2003. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms. Journal of Cell Science (JCS) 116 (7) , pp. 1349-57. 10.1242/jcs.00331
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Stephens, Philip, Cook, Helen, Hilton, Joanne, Jones, Christopher John, Haughton, Michele Fleur, Wyllie, Fiona Sandra, Skinner, Julia W., Harding, Keith Gordon, Kipling, David Glyn and Thomas, David William 2003. An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype. Experimental Cell Research 283 (1) , pp. 22-35. 10.1016/S0014-4827(02)00021-6

Baird, Duncan Martin, Rowson, Janet Maud, Wynford-Thomas, David and Kipling, David Glyn 2003. Extensive allelic variation and ultrashort telomeres in senescent human cells. Nature Genetics 33 (2) , pp. 203-207. 10.1038/ng1084

This list was generated on Wed Nov 14 04:16:49 2018 GMT.