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Number of items: 56.

McWilliams, Thomas, Barini, Erica, Pohjolan-Pirhonen, Risto, Brooks, Simon, Singh, Francois, Burel, Sophie, Balk, Kristin, Kumar, Atul, Montava-Garriga, Lambert, Prescott, Alan, Hassoun, Sidi, Mouton-Liger, Francois, Ball, Graeme, Hills, Rachel, Knebel, Axel, Ulusoy, Ayse, Di Monte, Donato, Tamjar, Jevgenia, Antico, Odetta, Fears, Kyle, Smith, Laura, Brambilla, Riccardo, Palin, Eino, Valori, Miko, Eerola-Rautio, Johanna, Tienari, Pentti, Corti, Olga, Dunnett, Stephen, Ganley, Ian, Suomalainen, Anu and Muqit, Miratul 2018. Phosphorylation of Parkin at Serine65 is essential for its activation in vivo. Open Biology 8 , 180108. 10.1098/rsob.180108

Harrison, David, Roberton, Victoria, Vinh, Ngoc-Nga, Brooks, Simon, Dunnett, Stephen and Rosser, Anne 2018. The effect of tissue preparation and donor age on striatal graft morphology in the mouse. Cell Transplantation 27 (2) , pp. 230-244. 10.1177/0963689717744788

McWilliams, T, Prescott, A, Montava-Garriga, L, Ball, G, Singh, F, Barini, E, Muqit, M, Brooks, Simon and Ganley, I 2018. Basal mitophagy occurs independently of PINK1 in mouse tissues of high metabolic demand. Cell Metabolism 27 (2) , pp. 439-449. 10.1016/j.cmet.2017.12.008

Bragg, Robert M., Coffey, Sydney R., Weston, Rory M., Ament, Seth A., Cantle, Jeffrey P., Minnig, Shawn, Funk, Cory C., Shuttleworth, Dominic D., Woods, Emily L., Sullivan, Bonnie R., Jones, Lindsey, Glickenhaus, Anne, Anderson, John S., Anderson, Michael D., Dunnett, Stephen Bruce, Wheeler, Vanessa C., MacDonald, Marcy E., Brooks, Simon P., Price, Nathan D. and Carroll, Jeffrey B. 2017. Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease. Scientific Reports 7 , 41570. 10.1038/srep41570

Yhnell, Emma, Dunnett, Stephen and Brooks, Simon 2016. A longitudinal operant assessment of cognitive and behavioural changes in the HdhQ111 mouse model of Huntington's Disease. PLoS ONE 11 (10) , e0164072. 10.1371/journal.pone.0164072

Yhnell, Emma, Dunnett, Stephen Bruce and Brooks, Simon Philip 2016. A longitudinal motor characterisation of the HdhQ111 mouse model of Huntington's Disease. Journal of Huntington's Disease 5 (2) , pp. 149-161. 10.3233/JHD-160191

Brooks, Simon Philip 2016. Foreword. Journal of Neuroscience Methods 265 , pp. 1-2. 10.1016/j.jneumeth.2016.01.011

Yhnell, Emma, Dunnett, Stephen Bruce and Brooks, Simon Philip 2016. The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease. Journal of Neuroscience Methods 265 , pp. 72-80. 10.1016/j.jneumeth.2015.08.022

Bayram-Weston, Zubeyde, Olsen, Elliott, Harrison, David, Dunnett, Stephen Bruce and Brooks, Simon 2016. Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease. Journal of Neuroscience Methods 265 , pp. 81-88. 10.1016/j.jneumeth.2015.09.033

Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2016. Comparison of mHTT antibodies in Huntington's disease mouse models reveal specific binding profiles and steady-state ubiquitin levels with disease development. PloS One 10.1371/journal.pone.0155834

Yhnell, Emma, Lelos, Mariah Jillian, Dunnett, Stephen Bruce and Brooks, Simon Philip 2016. Cognitive training modifies disease symptoms in a mouse model of Huntington's disease. Experimental Neurology 282 , pp. 19-26. 10.1016/j.expneurol.2016.05.008

Yhnell, Emma, Lelos, Mariah Jillian, Dunnett, Stephen Bruce and Brooks, Simon Philip 2016. L30 Cognitive training improves disease symptoms in a mouse model of huntington's disease. Journal of Neurology, Neurosurgery & Psychiatry 87 (Supp 1) , A100-A101. 10.1136/jnnp-2016-314597.285

Bayram-Weston, Zubeyde, Stone, Timothy C., Giles, Peter James, Elliston, Linda Anne, Janghra, Narinder, Higgs, Gemma, Holmans, Peter Alan, Dunnett, Stephen Bruce, Brooks, Simon Philip and Jones, Lesley 2015. Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence. BMC Genomics 16 (1) , 1079. 10.1186/s12864-015-2251-4

Bowles, Kathryn R., Brooks, Simon P., Dunnett, Stephen Bruce and Jones, Lesley 2015. Huntingtin subcellular localisation is regulated by Kinase signalling activity in the StHdhQ111 model of HD. PLoS ONE 10 (12) , e0144864. 10.1371/journal.pone.0144864

Steventon, Jessica, Harrison, David John, Trueman, Rebecca C., Rosser, Anne Elizabeth, Jones, Derek K. and Brooks, Simon Philip 2015. In Vivo MRI evidence that neuropathology is attenuated by cognitive enrichment in the Yac128 Huntington's Disease mouse model. Journal of Huntington's Disease 4 (2) , pp. 149-160. 10.3233/JHD-150147

Brooks, Simon Philip and Dunnett, Stephen Bruce 2015. Mouse models of Huntington's disease. Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease, Current Topics in Behavioral Neurosciences, vol. 22. Berlin: Springer, pp. 101-133. (10.1007/7854_2013_256)

Yhnell, Emma, Dunnett, Stephen Bruce and Brooks, Simon Philip 2014. C04 A longitudinal behavioural characterisation of the HDHQ111 mouse model of Huntington's Disease. Journal of Neurology, Neurosurgery & Psychiatry 85 (Supp 1) , A26. 10.1136/jnnp-2014-309032.77

Hughes, Alis, Mort, Matthew Edwin, Elliston, Linda Anne, Thomas, Rhian M., Brooks, Simon Philip, Dunnett, Stephen Bruce and Jones, Lesley 2014. Identification of novel alternative splicing events in the Huntingtin gene and assessment of the functional consequences using structural protein homology modelling. Journal of Molecular Biology 426 (7) , pp. 1428-1438. 10.1016/j.jmb.2013.12.028

Brooks, Simon Philip and Dunnett, Stephen Bruce 2013. Cognitive deficits in animal models of basal ganglia disorders. Brain Research Bulletin 92 , pp. 29-40. 10.1016/j.brainresbull.2012.04.011

Peters, Owen Morgan, Shelkovnikova, Tatyana, Tarasova, Tatiana, Springe, Signe, Kukharsky, Michail S., Smith, Gaynor A., Brooks, Simon Philip, Kozin, Sergey A., Kotelevtsev, Yury, Bachurin, Sergey O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease 36 (3) , pp. 589-596. 10.3233/JAD-130071

Harrison, David John, Busse, Monica, Openshaw, Rebecca, Rosser, Anne Elizabeth, Dunnett, Stephen Bruce and Brooks, Simon Philip 2013. Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model. Experimental Neurology 248 , pp. 457-469. 10.1016/j.expneurol.2013.07.014

Dunnett, Stephen Bruce, Fuller, Anna, Rosser, Anne Elizabeth and Brooks, Simon Philip 2012. A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions. Brain Research Bulletin 88 (2-3) , pp. 237-250. 10.1016/j.brainresbull.2010.10.005

Dunnett, Stephen Bruce, Heuer, Andreas, Lelos, Mariah Jillian, Brooks, Simon Philip and Rosser, Anne Elizabeth 2012. Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats. Brain Research Bulletin 88 (2-3) , pp. 251-260. 10.1016/j.brainresbull.2011.04.002

Deschepper, Mia Pieter, Hoogendoorn, Bastiaan, Brooks, Simon Philip, Dunnett, Stephen Bruce and Jones, Lesley 2012. Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes. Brain Research Bulletin 88 (2-3) , pp. 210-222. 10.1016/j.brainresbull.2011.01.012

Brooks, Simon Philip, Higgs, Gemma, Jones, Lesley and Dunnett, Stephen Bruce 2012. Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin 88 (2-3) , pp. 148-155. 10.1016/j.brainresbull.2010.05.003

Brooks, Simon Philip, Higgs, Gemma, Jones, Lesley and Dunnett, Stephen Bruce 2012. Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice. Brain Research Bulletin 88 (2-3) , pp. 182-188. 10.1016/j.brainresbull.2010.05.004

Bayram-Weston, Zubeyde, Torres, Eduardo Miguel, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh((CAG)150) Huntington's disease knock-in mouse. Brain Research Bulletin 88 (2-3) , pp. 189-198. 10.1016/j.brainresbull.2011.03.014

Brooks, Simon Philip, Higgs, Gemma, Janghra, Nari, Jones, Lesley and Dunnett, Stephen Bruce 2012. Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin 88 (2-3) , pp. 113-120. 10.1016/j.brainresbull.2010.05.005

Brooks, Simon Philip, Janghra, Nari, Workman, Victoria Louise, Bayram-Weston, Zubeyde, Jones, Lesley and Dunnett, Stephen Bruce 2012. Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin 88 (2-3) , pp. 94-103. 10.1016/j.brainresbull.2011.01.010

Trueman, Rebecca C., Dunnett, Stephen Bruce, Jones, Lesley and Brooks, Simon Philip 2012. Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 163-170. 10.1016/j.brainresbull.2011.10.019

Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice. Brain Research Bulletin 88 (2-3) , pp. 137-147. 10.1016/j.brainresbull.2011.05.005

Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice. Brain Research Bulletin 88 (2-3) , pp. 104-112. 10.1016/j.brainresbull.2011.07.009

Trueman, Rebecca C., Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Early onset deficits on the delayed alternation task in the HdhQ92 knock-in mouse model of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 156-162. 10.1016/j.brainresbull.2011.03.012

Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin 88 (2-3) , pp. 171-181. 10.1016/j.brainresbull.2011.03.013

Trueman, Rebecca C., Dunnett, Stephen Bruce and Brooks, Simon Philip 2012. Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 261-275. 10.1016/j.brainresbull.2011.03.015

Brooks, Simon Philip, Janghra, Narinder, Higgs, Gemma V., Bayram-Weston, Zubeyde, Heuer, Andreas, Jones, Lesley and Dunnett, Stephen Bruce 2012. Selective cognitive impairment in the YAC128 Huntington's disease mouse. Brain Research Bulletin 88 (2-3) , pp. 121-129. 10.1016/j.brainresbull.2011.05.010

Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2012. Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line. Brain Research Bulletin 88 (2-3) , pp. 130-136. 10.1016/j.brainresbull.2011.06.008

Fielding, Steven A., Brooks, Simon Philip, Klein, Alexander, Bayram-Weston, Zubeyde, Jones, Lesley and Dunnett, Stephen Bruce 2012. Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 223-236. 10.1016/j.brainresbull.2011.09.011

Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2012. Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 81-93. 10.1016/j.brainresbull.2011.10.002

Bowles, Kathryn R., Brooks, Simon Philip, Dunnett, Stephen Bruce and Jones, Lesley 2012. Gene expression and behaviour in mouse models of HD. Brain Research Bulletin 88 (2-3) , pp. 276-284. 10.1016/j.brainresbull.2011.07.021

Giles, Peter James, Elliston, Linda Anne, Higgs, Gemma, Brooks, Simon Philip, Dunnett, Stephen Bruce and Jones, Lesley 2012. Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease. Brain Research Bulletin 88 (2-3) , pp. 199-209. 10.1016/j.brainresbull.2011.10.001

Bayram-Weston, Zubeyde, Jones, Lesley, Dunnett, Stephen Bruce and Brooks, Simon P. 2012. B08 Differential sensitivity of aggregate markers in HdhQ150 and YAC128 HD mouse models. Journal of Neurology, Neurosurgery & Psychiatry 83 (Suppl) , A8-A8. 10.1136/jnnp-2012-303524.24

Busse, Monica, Khalil, Hanan, Quinn, Lori, Brooks, Simon Philip and Rosser, Anne Elizabeth 2012. Practice, progress and future directions for physical therapies in Huntington's Disease. Journal of Huntington's Disease 1 (2) , pp. 175-185. 10.3233/JHD-120025

Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2010. Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task [Meeting abstract]. Journal of Neurology, Neurosurgery and Psychiatry 81 (1) , A9-A10. 10.1136/jnnp.2010.222570.29

Twohig, Jason Peter, Roberts, Malcolm I., Gavalda, Nuria, Rees-Taylor, Emma Louise, Giralt, Albert, Adams, Deborah, Brooks, Simon Philip, Bull, Melanie Jane, Calder, Claudia Jane, Cuff, Simone, Yong, Audrey Alice, Alberch, Jordi, Davies, Alun M., Dunnett, Stephen Bruce, Tolkovsky, Aviva M. and Wang, Edward Chung Yern 2010. Age-dependent maintenance of motor controland corticostriatal innervation by death receptor 3. Journal of Neuroscience 30 (10) , pp. 3782-3792. 10.1523/JNEUROSCI.1928-09.2010

Brooks, Simon Philip, Fielding, Steven A., Döbrössy, Màtè, von Hörsten, Stephan and Dunnett, Stephen Bruce 2009. Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance. Brain Research Bulletin 79 (5) , pp. 310-315. 10.1016/j.brainresbull.2009.03.003

Brooks, Simon Philip and Dunnett, Stephen Bruce 2009. Lesions of the premotor and supplementary motor areas fail to prevent implicit learning in the operant serial implicit learning task. Brain Research 1284 , pp. 116-124. 10.1016/j.brainres.2009.05.081

Trueman, Rebecca C., Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2009. Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease. Behavioural Brain Research 203 (2) , pp. 215-222. 10.1016/j.bbr.2009.05.006

Brooks, Simon Philip and Dunnett, Stephen Bruce 2009. Tests to assess motor phenotype in mice: a user's guide. Nature Reviews Neurosciences 10 (7) , pp. 519-529. 10.1038/nrn2652

Hodges, Angela Kaye, Hughes, Gareth, Brooks, Simon Philip, Elliston, Linda Anne, Holmans, Peter Alan, Dunnett, Stephen Bruce and Jones, Lesley 2008. Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease. Genes, Brain and Behavior 7 (3) , pp. 288-299. 10.1111/j.1601-183X.2007.00350.x

Trueman, Rebecca C., Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2008. Time course of choice reaction time deficits in the Hdh Q92/Q92 knock-in mouse model of Huntington's disease. Behavioural Brain Research 189 (2) , pp. 317-334. 10.1016/j.bbr.2008.01.020

Brooks, Simon Philip, Trueman, Rebecca C. and Dunnett, Stephen Bruce 2007. Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task. Brain Research 1185 , pp. 179-188. 10.1016/j.brainres.2007.09.017

Trueman, Rebecca C., Brooks, Simon Philip, Jones, Lesley and Dunnett, Stephen Bruce 2007. The operant serial implicit learning task reveals early onset motor learning deficits in the HdhQ92 knock-in mouse model of Huntington's disease. European Journal of Neuroscience 25 (2) , pp. 551-558. 10.1111/j.1460-9568.2007.05307.x

Brooks, Simon, Betteridge, H., Trueman, R.C., Jones, Lesley and Dunnett, S.B. 2006. Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease. Brain Research Bulletin 69 (4) , pp. 452-7. 10.1016/j.brainresbull.2006.02.011

Brooks, Simon P., Higgs, G., Trueman, R. C., Dunnett, Stephen Bruce, Cheng, P., Redfern, A. R. and Jones, Lesley 2005. Longitudinal behavioural characterisation of the Q92 mouse line. Journal of Neurology, Neurosurgery and Psychiatry 76 , A48-A48.

Hughes, G. P., Brooks, Simon P., Hodges, A. H., Holmans, Peter Alan, Thomas, J. M., Goldstein, D., Dunnett, Stephen Bruce and Jones, Lesley 2005. Integrating behaviour and brain gene expression in Huntington's disease transgenic mouse models. Journal of Neurology, Neurosurgery and Psychiatry 76 , A41-A41.

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