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Online Research @ Cardiff

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Browse by Current Cardiff authors

Number of items: 41.

Worthy, Harley L, Sabah Auhim, Husam, Jamieson, W David, Pope, Jacob R, Wall, Aaron, Batchlor, Robert, Johnson, Rachel L, Watkins, Daniel W, Rizkallah, Pierre, Castell, Oliver K and Jones, D Dafydd 2019. Positive functional synergy of structurally integrated artificial protein dimers assembled by Click chemistry. Communications Chemistry 2 , 83. 10.1038/s42004-019-0185-5

Gulácsy, Christina E., Meade, Richard, Catici, Dragana A. M., Soeller, Christian, Pantos, G. Dan, Jones, D. Dafydd, Alibhai, Dominic, Jepson, Mark, Valev, Ventsislav K., Mason, Jody M., Williams, Robert J. and Pudney, Christopher R. 2019. Excitation-energy-dependent molecular beacon detects early stage neurotoxic Aβ aggregates in the presence of cortical neurons. ACS Chemical Neuroscience 10 (3) , pp. 1240-1250. 10.1021/acschemneuro.8b00322

Zaki, Athraa, Hartley, Andrew, Reddington, Samuel, Thomas, Suzanne, Watson, Peter, Hayes, Anthony, Moskalenko, Andy, Craciun, Monica, MacDonald, John, Jones, Darran Dafydd and Elliott, Martin 2018. Defined covalent assembly of protein molecules on graphene using a genetically encoded photochemical reaction handle. RSC Advances 8 , pp. 5768-5775. 10.1039/c7ra11166e

Elliott, Martin and Jones, Darran Dafydd 2018. Approaches to single molecule studies of metalloprotein electron transfer using scanning probe-based techniques. Biochemical Society Transactions 46 (1) , pp. 1-9. 10.1042/BST20170229

Halliwell, Lisa M., Jathoul, Amit P., Bate, Jack P., Worthy, Harley L., Anderson, James C., Jones, D. Dafydd and Murray, James Augustus Henry 2018. ΔFlucs: brighter photinus pyralis firefly luciferases identified by surveying consecutive single amino acid deletion mutations in a thermostable variant. Biotechnology and Bioengineering 115 (1) , pp. 50-59. 10.1002/bit.26451

Freeley, Mark, Worthy, Harley L., Ahmed, Rochelle, Bowen, Benjamin, Watkins, Daniel, MacDonald, John, Zheng, Ming, Jones, Darran Dafydd and Palma, Matteo 2017. Site-specific one-to-one click coupling of single proteins to individual carbon nanotubes: a single-molecule approach. Journal of the American Chemical Society 139 (49) , pp. 17834-17840. 10.1021/jacs.7b07362

Marth, Gabriella, Hartley, Andrew M., Reddington, Samuel C., Sargisson, Lauren L., Parcollet, Marlène, Dunn, Katherine E., Jones, Darran Dafydd and Stulz, Eugen 2017. Precision templated bottom-up multiprotein nanoassembly through defined click chemistry linkage to DNA. ACS Nano 11 (5) , pp. 5003-5010. 10.1021/acsnano.7b01711

Hartley, Andrew M., Worthy, Harley L., Reddington, Samuel, Rizkallah, Pierre and Jones, Darran Dafydd 2016. Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chemical Science 7 (10) , pp. 6484-6491. 10.1039/C6SC00944A

Arpino, James A. J., Baldwin, Amy Joy, McGarrity, Adam R., Tippmann, Eric M. and Jones, Darran Dafydd 2015. In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification. PLoS ONE 10 (5) , e0127504. 10.1371/journal.pone.0127504

Hartley, Andrew M., Zaki, Athraa J., McGarrity, Adam R., Robert-Ansart, Cecile, Moskalenko, Andriy V., Jones, Gareth F., Craciun, Monica F., Russo, Saverio, Elliott, Martin, MacDonald, John Emyr and Jones, Darran Daffydd 2015. Functional modulation and directed assembly of an enzyme through designed non-natural post-translation modification. Chemical Science 6 (7) , pp. 3712-3717. 10.1039/C4SC03900A

Reddington, Samuel C., Baldwin, Amy Joy, Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M. and Jones, Darran Dafydd 2015. Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence. Chemical Science 6 (2) , pp. 1159-1166. 10.1039/C4SC02827A

Reddington, Samuel C., Driezis, Sarunas, Hartley, Andrew M., Watson, Peter Duncan, Rizkallah, Pierre J. and Jones, Darran Dafydd 2015. Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein. RSC Advances 5 (95) , pp. 77734-77738. 10.1039/C5RA13552D

Jones, Darran Dafydd, Arpino, James A. J., Baldwin, Amy Joy and Edmundson, Matthew C. 2014. Transposon-based approaches for generating novel molecular diversity during directed evolution. In: Gillam, Elizabeth M. J., Copp, Janine M. and Ackerley, David eds. Directed Evolution Library Creation: Methods and Protocols, Vol. 1179. Methods in Molecular Biology, Springer, pp. 159-172. (10.1007/978-1-4939-1053-3_11)

Arpino, James Alexander Joseph, Reddington, Samuel C., Halliwell, Lisa Marie, Rizkallah, Pierre and Jones, Darran Dafydd 2014. Random single amino acid deletion sampling unveils structural tolerance and the benefits of helical registry shift on GFP folding and structure. Structure 22 (6) , pp. 889-898. 10.1016/j.str.2014.03.014

Arpino, James Alexander Joseph, Rizkallah, Pierre and Jones, Darran Dafydd 2014. Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallographica Section D Biological Crystallography 70 (8) , pp. 2152-2162. 10.1107/S139900471401267X

Reddington, Samuel C., Rizkallah, Pierre, Watson, Peter Duncan, Pearson, Rachel, Tippmann, Eric Michael and Jones, Darran Dafydd 2013. Different photochemical events of a genetically encoded phenyl azide define and modulate GFP fluorescence. Angewandte Chemie - International Edition 52 (23) , pp. 5974-5977. 10.1002/anie.201301490

Morris, Josephine Lydia, Reddington, Samuel C., Murphy, Damien Martin, Jones, Darran Dafydd, Platts, James Alexis and Tippmann, Eric Michael 2013. Aryl azide photochemistry in defined protein environments. Organic Letters 15 (4) , pp. 728-731. 10.1021/ol3028779

Reddington, Samuel C., Watson, Peter Duncan, Rizkallah, Pierre, Tippmann, Eric Michael and Jones, Darran Dafydd 2013. Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry. Biochemical Society Transactions 41 (5) , pp. 1177-1182. 10.1042/BST20130094

Della Pia, Eduardo Antonio, Macdonald, John Emyr, Elliott, Martin and Jones, Darran Dafydd 2012. Direct binding of a redox protein for single-molecule electron transfer measurements. Small 8 (15) , pp. 2341-2344. 10.1002/smll.201102416

Arpino, James, Czapinska, Honorata, Piasecka, Anna, Edwards, Wayne Robert, Barker, Paul, Gajda, Michal J., Bochler, Matthias and Jones, Darran Dafydd 2012. Structural basis for efficient chromophore communication and energy transfer in a constructed didomain protein scaffold. Journal of the American Chemical Society 134 (33) , pp. 13632-13640. 10.1021/ja301987h

Della Pia, Eduardo Antonio, Elliott, Martin, Jones, Darran Dafydd and Macdonald, J. Emyr 2012. Orientation-dependent electron transport in a single redox protein. ACS Nano 6 (1) , pp. 355-361. 10.1021/nn2036818

Reddington, Samuel C., Tippmann, Eric Michael and Jones, Darran Dafydd 2012. Residue choice defines efficiency and influence of bioorthogonal protein modification via genetically encoded strain promoted Click chemistry. Chemical Communications 48 (67) , pp. 8419-8421. 10.1039/c2cc31887c

Arpino, James, Rizkallah, Pierre and Jones, Darran Dafydd 2012. Crystal structure of enhanced green fluorescent protein to 1.35 Å resolution reveals alternative conformations for Glu222. PLoS ONE 7 (10) , e47132. 10.1371/journal.pone.0047132

Gamble, Michael David, Kunze, Georg, Brancale, Andrea, Wilson, Keith S. and Jones, Darran Dafydd 2012. The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin. FEBS Open Bio 2 , pp. 209-215. 10.1016/j.fob.2012.07.001

Della Pia, Eduardo Antonio, Chi, Qijin, Macdonald, John Emyr, Ulstrup, Jens, Jones, Darran Dafydd and Elliott, Martin 2012. Fast electron transfer through a single molecule natively structured redox protein. Nanoscale 4 (22) , pp. 7106-7113. 10.1039/c2nr32131a

Della Pia, Eduardo Antonio, Chi, Qijin, Elliott, Martin, Macdonald, John Emyr, Ulstrup, Jens and Jones, Darran Dafydd 2012. Redox tuning of cytochrome b562 through facile metal porphyrin substitution. Chemical Communications 48 (86) , pp. 10624-10626. 10.1039/c2cc34302a

Jones, Darran Dafydd 2011. Recombining low homology, functionally rich regions of bacterial subtilisins by combinatorial fragment exchange. PLoS ONE 6 (9) , e24319. 10.1371/journal.pone.0024319

Gamble, Michael David, Kunze, Georg, Dodson, Eleanor J., Wilson, Keith S. and Jones, Darran Dafydd 2011. Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism. Proceedings of the National Academy of Sciences 108 (9) , pp. 3536-3541. 10.1073/pnas.1014229108

Della Pia, Eduardo Antonio, Chi, Qijin, Jones, Darran Dafydd, Macdonald, John Emyr, Ulstrup, Jens and Elliott, Martin 2011. Single-molecule mapping of long-range electron transport for a cytochrome b562 variant. Nano Letters 11 (1) , pp. 176-182. 10.1021/nl103334q

Vevodova, Jiyka, Gamble, Michael David, Kunze, Georg, Ariza, Antonio, Dodson, Eleanor, Jones, Darran Dafydd and Wilson, Keith S. 2010. Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure 18 (6) , pp. 744-755. 10.1016/j.str.2010.03.008

Edwards, Wayne Robert, Williams, Abigail J., Morris, Josephine Lydia, Baldwin, Amy Joy, Allemann, Rudolf Konrad and Jones, Darran Dafydd 2010. Regulation of β-Lactamase activity by remote binding of Heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49 (31) , pp. 6541-6549. 10.1021/bi100793y

Baldwin, Amy Joy, Arpino, James Alexander, Edwards, W. R., Tippmann, Eric Michael and Jones, Darran Dafydd 2009. Expanded chemical diversity sampling through whole protein evolution. Molecular Biosystems 5 (7) , pp. 764-766. 10.1039/B904031E

Stott, K. M., Yusof, A. M., Perham, R. N. and Jones, Darran Dafydd 2009. A Surface Loop Directs Conformational Switching of a Lipoyl Domain Between a Folded and a Novel Misfolded Structure. Structure 17 (8) , pp. 1117-1127. 10.1016/j.str.2009.07.001

Baldwin, Amy Joy, Busse, K., Simm, A. M. and Jones, Darran Dafydd 2008. Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx). Nucleic Acids Research 36 (13) , e77. 10.1093/nar/gkn358

Meltzer, Michael, Hasenbein, Sonja, Hauske, Patrick, Kucz, Nicolette, Merdanovic, Melisa, Grau, Sandra, Beil, Alexandra, Jones, Darran Dafydd, Krojer, Tobias, Clausen, Tim, Ehrmann, Michael and Kaiser, Markus 2008. Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control. Angewandte Chemie - International Edition 47 (7) , pp. 1332-1334. 10.1002/anie.200703273

Edwards, W. R., Busse, K., Allemann, Rudolf Konrad and Jones, Darran Dafydd 2008. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research 36 (13) 10.1093/nar/gkn363

Jones, Darran Dafydd and Perham, R. N. 2008. The role of loop and Î²-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119

Jones, Darran Dafydd and Perham, Richard N. 2007. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119

Jones, Darran Dafydd and Barker, P.D. 2005. Controlling self-assembly by linking protein folding, DNA binding and the redox chemistry of heme. Angewandte Chemie International Edition , pp. 6337-6341. 10.1002/anie.200463035

Jones, Darran Dafydd 2005. Triplet nucleotide removal at random positions in a target gene: the tolerance of TEM-1 β-lactamase to an amino acid deletion. Nucleic Acids Research 33 (9) 10.1093/nar/gni077

Jones, Darran Dafydd, Perham, R.N., Reche, P.A. and Stott, K.M. 2001. Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. Journal of Molecular Biology , pp. 49-60. 10.1006/jmbi.2000.4257

This list was generated on Sat Dec 14 05:58:42 2019 GMT.

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