ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 54.
| Worthy, Harley L., Williamson, Lainey J., Auhim, Husam Sabah, Leppla, Stephen H., Sastalla, Inka, Jones, D. Dafydd, Rizkallah, Pierre J. and Berry, Colin 2021. The crystal sructure of Bacillus cereus HblL1. Toxins 13 (4) , 253. 10.3390/toxins13040253 |
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Auhim, Husam, Grigorenko, Bella L, Harris, Tessa, Aksakal, Ozan, Polyakov, Igor, Berry, Colin, dos Passos Gomes, Gabriel, Alabugin, Igor, Rizkallah, Pierre, Nemukhin, Alexander and Jones, D. Dafydd
2021.
Stalling chromophore synthesis of the fluorescent protein Venus reveals the molecular basis of the final oxidation step.
Chemical Science
10.1039/D0SC06693A
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Pope, Jacob R., Johnson, Rachel L., Jamieson, W. David, Worthy, Harley L., Kailasam, Senthilkumar, Ahmed, Rochelle D., Taban, Ismail, Auhim, Husam Sabah, Watkins, Daniel W., Rizkallah, Pierre, Castell, Oliver and Jones, D. Dafydd
2021.
Association of fluorescent protein pairs and it's significant impact on fluorescence and energy transfer.
Advanced Science
8
(1)
, 2003167.
10.1002/advs.202003167
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Karuna, Arnica, Masia, Francesco, Chappell, Sally, Errington, Rachel, Hartley, Andrew M., Jones, D. Dafydd, Borri, Paola and Langbein, Wolfgang
2020.
Quantitative imaging of B1 cyclin expression across the cell cycle using green fluorescent protein tagging and epi-fluorescence.
Cytometry Part A
97
(10)
, pp. 1066-1072.
10.1002/cyto.a.24038
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| Bowen, Benjamin J., McGarrity, Adam R., Szeto, Jenn-Yeu A., Pudney, Christopher R. and Jones, D. Dafydd 2020. Switching protein metalloporphyrin binding specificity by design from iron to fluorogenic zinc. Chemical Communications 56 (31) , pp. 4308-4311. 10.1039/D0CC00596G |
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| Thomas, Suzanne K., Jamieson, W. David, Gwyther, Rebecca E. A., Bowen, Benjamin J., Beachey, Adam, Worthy, Harley L., MacDonald, J. Emyr, Elliott, Martin, Castell, Oliver K. and Jones, D. Dafydd 2020. Site-specific protein photochemical covalent attachment to carbon nanotube side walls and its electronic impact on single molecule function. Bioconjugate Chemistry 31 (3) , pp. 584-594. 10.1021/acs.bioconjchem.9b00719 |
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Gwyther, Rebecca E.A., Jones, D. Dafydd and Worthy, Harley L.
2019.
Better together: building protein oligomers naturally and by design.
Biochemical Society Transactions
47
(6)
, pp. 1773-1780.
10.1042/BST20190283
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Worthy, Harley L., Sabah Auhim, Husam, Jamieson, W. David, Pope, Jacob R., Wall, Aaron, Batchlor, Robert, Johnson, Rachel L., Watkins, Daniel W., Rizkallah, Pierre, Castell, Oliver K. and Jones, D. Dafydd
2019.
Positive functional synergy of structurally integrated artificial protein dimers assembled by Click chemistry.
Communications Chemistry
2
, 83.
10.1038/s42004-019-0185-5
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| Gulácsy, Christina E., Meade, Richard, Catici, Dragana A. M., Soeller, Christian, Pantos, G. Dan, Jones, D. Dafydd, Alibhai, Dominic, Jepson, Mark, Valev, Ventsislav K., Mason, Jody M., Williams, Robert J. and Pudney, Christopher R. 2019. Excitation-energy-dependent molecular beacon detects early stage neurotoxic Aβ aggregates in the presence of cortical neurons. ACS Chemical Neuroscience 10 (3) , pp. 1240-1250. 10.1021/acschemneuro.8b00322 |
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| Zaki, Athraa, Hartley, Andrew, Reddington, Samuel, Thomas, Suzanne, Watson, Peter, Hayes, Anthony, Moskalenko, Andy, Craciun, Monica, MacDonald, John, Jones, Darran Dafydd and Elliott, Martin 2018. Defined covalent assembly of protein molecules on graphene using a genetically encoded photochemical reaction handle. RSC Advances 8 , pp. 5768-5775. 10.1039/c7ra11166e |
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| Elliott, Martin and Jones, Darran Dafydd 2018. Approaches to single molecule studies of metalloprotein electron transfer using scanning probe-based techniques. Biochemical Society Transactions 46 (1) , pp. 1-9. 10.1042/BST20170229 |
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| Halliwell, Lisa M., Jathoul, Amit P., Bate, Jack P., Worthy, Harley L., Anderson, James C., Jones, D. Dafydd and Murray, James Augustus Henry 2018. ΔFlucs: brighter photinus pyralis firefly luciferases identified by surveying consecutive single amino acid deletion mutations in a thermostable variant. Biotechnology and Bioengineering 115 (1) , pp. 50-59. 10.1002/bit.26451 |
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Freeley, Mark, Worthy, Harley L., Ahmed, Rochelle, Bowen, Ben, Watkins, Daniel, MacDonald, J. Emyr, Zheng, Ming, Jones, D. Dafydd and Palma, Matteo
2017.
Site-specific one-to-one click coupling of single proteins to individual carbon nanotubes: a single-molecule approach.
Journal of the American Chemical Society
139
(49)
, pp. 17834-17840.
10.1021/jacs.7b07362
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Marth, Gabriella, Hartley, Andrew M., Reddington, Samuel C., Sargisson, Lauren L., Parcollet, Marlène, Dunn, Katherine E., Jones, D. Dafydd and Stulz, Eugen
2017.
Precision templated bottom-up multiprotein nanoassembly through defined click chemistry linkage to DNA.
ACS Nano
11
(5)
, pp. 5003-5010.
10.1021/acsnano.7b01711
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Hartley, Andrew M., Worthy, Harley L., Reddington, Samuel C., Rizkallah, Pierre J. and Jones, D. Dafydd
2016.
Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chemical Science
7
(10)
, pp. 6484-6491.
10.1039/C6SC00944A
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| Hartley, Andrew M., Zaki, Athraa J., McGarrity, Adam R., Robert-Ansart, Cecile, Moskalenko, Andriy V., Jones, Gareth F., Craciun, Monica F., Russo, Saverio, Elliott, Martin, MacDonald, J. Emyr and Jones, D. Daffydd 2015. Functional modulation and directed assembly of an enzyme through designed non-natural post-translation modification. Chemical Science 6 (7) , pp. 3712-3717. 10.1039/C4SC03900A |
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| Arpino, James A. J., Baldwin, Amy Joy, McGarrity, Adam R., Tippmann, Eric M. and Jones, Darran Dafydd 2015. In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification. PLoS ONE 10 (5) , e0127504. 10.1371/journal.pone.0127504 |
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| Rohamare, Sonali, Gaikwad, Sushama, Jones, Dafydd, Bhavnani, Varsha, Pal, Jayanta, Sharma, Ranu and Chatterjee, Prathit 2015. Cloning, expression and in silico studies of a serine protease from a marine actinomycete (Nocardiopsis sp. NCIM 5124). Process Biochemistry 50 (3) , pp. 378-387. 10.1016/j.procbio.2014.12.025 |
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Reddington, Samuel C., Baldwin, Amy J., Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M. and Jones, D. Dafydd
2015.
Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence.
Chemical Science
6
(2)
, pp. 1159-1166.
10.1039/C4SC02827A
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Reddington, Samuel C., Driezis, Sarunas, Hartley, Andrew M., Watson, Peter Duncan, Rizkallah, Pierre J. and Jones, Darran Dafydd
2015.
Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein.
RSC Advances
5
(95)
, pp. 77734-77738.
10.1039/C5RA13552D
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| Jones, Darran Dafydd, Arpino, James A. J., Baldwin, Amy Joy and Edmundson, Matthew C. 2014. Transposon-based approaches for generating novel molecular diversity during directed evolution. In: Gillam, Elizabeth M. J., Copp, Janine M. and Ackerley, David eds. Directed Evolution Library Creation: Methods and Protocols, Vol. 1179. Methods in Molecular Biology, Springer, pp. 159-172. (10.1007/978-1-4939-1053-3_11) |
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Arpino, James Alexander Joseph, Reddington, Samuel C., Halliwell, Lisa Marie, Rizkallah, Pierre and Jones, Darran Dafydd
2014.
Random single amino acid deletion sampling unveils structural tolerance and the benefits of helical registry shift on GFP folding and structure.
Structure
22
(6)
, pp. 889-898.
10.1016/j.str.2014.03.014
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| Arpino, James Alexander Joseph, Rizkallah, Pierre and Jones, Darran Dafydd 2014. Structural and dynamic changes associated with beneficial engineered single-amino-acid deletion mutations in enhanced green fluorescent protein. Acta Crystallographica Section D Biological Crystallography 70 (8) , pp. 2152-2162. 10.1107/S139900471401267X |
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| Reddington, Samuel C., Rizkallah, Pierre, Watson, Peter Duncan, Pearson, Rachel, Tippmann, Eric Michael and Jones, Darran Dafydd 2013. Different photochemical events of a genetically encoded phenyl azide define and modulate GFP fluorescence. Angewandte Chemie - International Edition 52 (23) , pp. 5974-5977. 10.1002/anie.201301490 |
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| Morris, Josephine Lydia, Reddington, Samuel C., Murphy, Damien Martin, Jones, Darran Dafydd, Platts, James Alexis and Tippmann, Eric Michael 2013. Aryl azide photochemistry in defined protein environments. Organic Letters 15 (4) , pp. 728-731. 10.1021/ol3028779 |
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| Reddington, Samuel C., Watson, Peter Duncan, Rizkallah, Pierre, Tippmann, Eric Michael and Jones, Darran Dafydd 2013. Genetically encoding phenyl azide chemistry: new uses and ideas for classical biochemistry. Biochemical Society Transactions 41 (5) , pp. 1177-1182. 10.1042/BST20130094 |
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| Della Pia, Eduardo Antonio, Macdonald, John Emyr, Elliott, Martin and Jones, Darran Dafydd 2012. Direct binding of a redox protein for single-molecule electron transfer measurements. Small 8 (15) , pp. 2341-2344. 10.1002/smll.201102416 |
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| Arpino, James, Czapinska, Honorata, Piasecka, Anna, Edwards, Wayne Robert, Barker, Paul, Gajda, Michal J., Bochler, Matthias and Jones, Darran Dafydd 2012. Structural basis for efficient chromophore communication and energy transfer in a constructed didomain protein scaffold. Journal of the American Chemical Society 134 (33) , pp. 13632-13640. 10.1021/ja301987h |
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| Della Pia, Eduardo Antonio, Elliott, Martin, Jones, Darran Dafydd and Macdonald, J. Emyr 2012. Orientation-dependent electron transport in a single redox protein [RETRACTED]. ACS Nano 6 (1) , pp. 355-361. 10.1021/nn2036818 |
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| Reddington, Samuel C., Tippmann, Eric Michael and Jones, Darran Dafydd 2012. Residue choice defines efficiency and influence of bioorthogonal protein modification via genetically encoded strain promoted Click chemistry. Chemical Communications 48 (67) , pp. 8419-8421. 10.1039/c2cc31887c |
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| Arpino, James, Rizkallah, Pierre and Jones, Darran Dafydd 2012. Crystal structure of enhanced green fluorescent protein to 1.35 Å resolution reveals alternative conformations for Glu222. PLoS ONE 7 (10) , e47132. 10.1371/journal.pone.0047132 |
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| Gamble, Michael David, Kunze, Georg, Brancale, Andrea, Wilson, Keith S. and Jones, Darran Dafydd 2012. The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin. FEBS Open Bio 2 , pp. 209-215. 10.1016/j.fob.2012.07.001 |
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| Della Pia, Eduardo Antonio, Chi, Qijin, Macdonald, John Emyr, Ulstrup, Jens, Jones, Darran Dafydd and Elliott, Martin 2012. Fast electron transfer through a single molecule natively structured redox protein. Nanoscale 4 (22) , pp. 7106-7113. 10.1039/c2nr32131a |
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| Della Pia, Eduardo Antonio, Chi, Qijin, Elliott, Martin, Macdonald, John Emyr, Ulstrup, Jens and Jones, Darran Dafydd 2012. Redox tuning of cytochrome b562 through facile metal porphyrin substitution. Chemical Communications 48 (86) , pp. 10624-10626. 10.1039/c2cc34302a |
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| Jones, Darran Dafydd 2011. Recombining low homology, functionally rich regions of bacterial subtilisins by combinatorial fragment exchange. PLoS ONE 6 (9) , e24319. 10.1371/journal.pone.0024319 |
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| Gamble, Michael David, Kunze, Georg, Dodson, Eleanor J., Wilson, Keith S. and Jones, Darran Dafydd 2011. Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism. Proceedings of the National Academy of Sciences 108 (9) , pp. 3536-3541. 10.1073/pnas.1014229108 |
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| Della Pia, Eduardo Antonio, Chi, Qijin, Jones, Darran Dafydd, Macdonald, John Emyr, Ulstrup, Jens and Elliott, Martin 2011. Single-molecule mapping of long-range electron transport for a cytochrome b562 variant. Nano Letters 11 (1) , pp. 176-182. 10.1021/nl103334q |
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| Vevodova, Jiyka, Gamble, Michael David, Kunze, Georg, Ariza, Antonio, Dodson, Eleanor, Jones, Darran Dafydd and Wilson, Keith S. 2010. Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Structure 18 (6) , pp. 744-755. 10.1016/j.str.2010.03.008 |
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| Edwards, Wayne Robert, Williams, Abigail J., Morris, Josephine Lydia, Baldwin, Amy Joy, Allemann, Rudolf Konrad and Jones, Darran Dafydd 2010. Regulation of β-Lactamase activity by remote binding of Heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49 (31) , pp. 6541-6549. 10.1021/bi100793y |
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| Baldwin, Amy Joy, Arpino, James Alexander, Edwards, W. R., Tippmann, Eric Michael and Jones, Darran Dafydd 2009. Expanded chemical diversity sampling through whole protein evolution. Molecular Biosystems 5 (7) , pp. 764-766. 10.1039/B904031E |
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| Stott, K. M., Yusof, A. M., Perham, R. N. and Jones, Darran Dafydd 2009. A Surface Loop Directs Conformational Switching of a Lipoyl Domain Between a Folded and a Novel Misfolded Structure. Structure 17 (8) , pp. 1117-1127. 10.1016/j.str.2009.07.001 |
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| Baldwin, Amy Joy, Busse, K., Simm, A. M. and Jones, Darran Dafydd 2008. Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx). Nucleic Acids Research 36 (13) , e77. 10.1093/nar/gkn358 |
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| Meltzer, Michael, Hasenbein, Sonja, Hauske, Patrick, Kucz, Nicolette, Merdanovic, Melisa, Grau, Sandra, Beil, Alexandra, Jones, Darran Dafydd, Krojer, Tobias, Clausen, Tim, Ehrmann, Michael and Kaiser, Markus 2008. Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control. Angewandte Chemie - International Edition 47 (7) , pp. 1332-1334. 10.1002/anie.200703273 |
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| Edwards, W. R., Busse, K., Allemann, Rudolf Konrad and Jones, Darran Dafydd 2008. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research 36 (13) 10.1093/nar/gkn363 |
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| Jones, Darran Dafydd and Perham, R. N. 2008. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119 |
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| Jones, Darran Dafydd and Perham, Richard N. 2007. The role of loop and β-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. Biochemical Journal 409 , pp. 357-366. 10.1042/BJ20071119 |
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| Simm, Alan M., Baldwin, Amy Joy, Busse, Kathy and Jones, D. Dafydd 2007. Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 β-lactamase. FEBS Letters 581 (21) , pp. 3904-3908. 10.1016/j.febslet.2007.07.018 |
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| Jones, Darran Dafydd and Barker, P.D. 2005. Controlling self-assembly by linking protein folding, DNA binding and the redox chemistry of heme. Angewandte Chemie International Edition , pp. 6337-6341. 10.1002/anie.200463035 |
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| Jones, D. Dafydd and Barker, Paul D. 2004. Design and characterisation of an artificial DNA-binding cytochrome. ChemBioChem 5 (7) , pp. 964-971. 10.1002/cbic.200300569 |
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| Perham, Richard N., Jones, D. Dafydd, Chauhan, Hitesh J. and Howard, Mark J. 2002. Substrate channelling in 2-oxo acid dehydrogenase multienzyme complexes. Biochemical Society Transactions 30 (2) , 47–51. 10.1042/0300-5127:0300047 |
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| Jones, Darran Dafydd, Perham, R.N., Reche, P.A. and Stott, K.M. 2001. Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. Journal of Molecular Biology , pp. 49-60. 10.1006/jmbi.2000.4257 |
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| Jones, D. Dafydd, Stott, Katherine M., Howard, Mark J. and Perham, Richard N. 2000. Restricted motion of the lipoyl-lysine swinging arm in the pyruvate dehydrogenase complex of Escherichia coli†,‡. Biochemistry 39 (29) , 8448–8459. 10.1021/bi992978i |
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| Jones, D.Dafydd, Horne, H.James, Reche, Pedro A and Perham, Richard N 2000. Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Journal of Molecular Biology 295 (2) , pp. 289-306. 10.1006/jmbi.1999.3335 |
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