Browse by Current Cardiff authors

Huynh, Florence, Tailby, Matthew, Finniear, Aled, Stephens, Kevin, Allemann, Rudolf K. and Wirth, Thomas 2020. Accelerating biphasic biocatalysis through new process windows. Angewandte Chemie International Edition 59 (38) , pp. 16490-16495. 10.1002/anie.202005183

Elsherbini, Mohamed, Huynh, Florence, Dunbabin, Alice, Allemann, Rudolf and Wirth, Thomas 2020. Selective hydroboration - oxidation of terminal alkenes under flow conditions. Chemistry - A European Journal 26 (50) , pp. 11423-11425. 10.1002/chem.202001650

Adesina, Aduragbemi S., Swiderek, Katarzyna, Luk, Louis Y. P., Moliner, Vicent and Allemann, Rudolf K. 2020. Electric field measurements reveal the pivotal role of Cofactor-Substrate interaction in dihydrofolate reductase catalysis. ACS Catalysis 10 (14) , pp. 7907-7914. 10.1021/acscatal.0c01856

Johnson, Luke A., Dunbabin, Alice, Benton, Jennifer C. R., Mart, Robert J. and Allemann, Rudolf K. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59 (22) , pp. 8486-8490. 10.1002/anie.202001744 Item availability restricted.

Valikhani, Donya, Srivastava, Prabhakar L., Allemann, Rudolf K. and Wirth, Thomas 2020. Immobilised enzymes for sesquiterpene synthesis in batch and flow systems. ChemCatChem 12 (8) , pp. 2194-22197. 10.1002/cctc.201902135 Item availability restricted.

Day, Adam H., Ubler, Martin H., Best, Hannah L., Lloyd-Evans, Emyr, Mart, Robert J., Fallis, Ian A., Allemann, Rudolf K., Al-Wattar, Eman A. H., Keymer, Nathaniel I., Buurma, Niklaas J. and Pope, Simon J. A. 2020. Targeted cell imaging properties of a deep red luminescent iridium(III) complex conjugated with a c-Myc signal peptide. Chemical Science 11 (6) , pp. 1599-1606. 10.1039/C9SC05568A

Cresser-Brown, Joel, Rizkallah, Pierre, Jin, Yi, Roth, Christian, Miller, David J. and Allemann, Rudolf K. 2020. An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq. Acta Crystallographica Section F: Structural Biology Communications 76 (2) , pp. 81-85. 10.1107/S2053230X20001181

Allemann, Rudolf K, Scott, Alan F., Luk, Louis Y.-P., Tuñón, Iñaki and Moliner, Vicent 2019. Heavy enzymes and the rational redesign of protein catalysts. ChemBioChem 20 (22) , pp. 2807-2812. 10.1002/cbic.201900134

Angelastro, Antonio, Ruiz-Pernía, J. Javier, Tuñón, Iñaki, Moliner, Vicent, Luk, Louis Y. P. and Allemann, Rudolf K. 2019. Loss of hyperconjugative effects drives hydride transfer during dihydrofolate reductase catalysis. ACS Catalysis 9 (11) , pp. 10343-10349. 10.1021/acscatal.9b02839

Elsherbini, Mohamed, Allemann, Rudolf K. and Wirth, Thomas 2019. 'Dark' singlet oxygen made easy. Chemistry - A European Journal 25 (54) , pp. 12486-12490. 10.1002/chem.201903505

Demiray, Melodi, Miller, David J and Allemann, Rudolf K 2019. Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids. Beilstein Journal of Organic Chemistry 15 , pp. 2184-2190. 10.3762/bjoc.15.215

Kalvaitis, Mindaugas E., Johnson, Luke A., Mart, Robert J., Rizkallah, Pierre and Allemann, Rudolf K. 2019. A noncanonical chromophore reveals structural rearrangements of the light-oxygen-voltage domain upon photoactivation. Biochemistry 58 (22) , pp. 2608-2616. 10.1021/acs.biochem.9b00255

Scott, Alan F., Cresser-Brown, Joel, Williams, Thomas L., Rizkallah, Pierre J., Jin, Yi, Luk, Louis Y.-P. and Allemann, Rudolf K. 2019. Crystal structure and biophysical analysis of furfural detoxifying aldehyde reductase from clostridium beijerinkii. Applied and Environmental Microbiology 10.1128/AEM.00978-19

Ruiz-Pernía, J. Javier, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf K. 2019. Why are some enzymes dimers? flexibility and catalysis in Thermotoga maritima dihydrofolate reductase. ACS Catalysis 9 , pp. 5902-5911. 10.1021/acscatal.9b01250

Patel, Sanjay G., Sayers, Edward J., He, Lin, Narayan, Rohan, Williams, Thomas L., Mills, Emily M., Allemann, Rudolf K., Luk, Louis Y. P., Jones, Arwyn T. and Tsai, Yu-Hsuan 2019. Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. Scientific Reports 9 (1) , -. 10.1038/s41598-019-42456-8

Loizzi, Marianna, Miller, David J. and Allemann, Rudolf K. 2019. Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase. Organic & Biomolecular Chemistry 17 (5) , pp. 1206-1214. 10.1039/C8OB02821D

Kalash, Leen, Cresser-Brown, Joel, Habchi, Johnny, Morgan, Connor, Miller, David J., Glen, Robert C., Allemann, Rudolf K. and Bender, Andreas 2018. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space. European Journal of Medicinal Chemistry 157 , pp. 1264-1275. 10.1016/j.ejmech.2018.08.049

Huynh, Florence, Grundy, Daniel J., Jenkins, Robert L., Miller, David J. and Allemann, Rudolf K. 2018. Sesquiterpene synthase-catalysed formation of a new medium-sized cyclic terpenoid ether from farnesyl diphosphate analogues. Chembiochem 19 (17) , pp. 1834-1838. 10.1002/cbic.201800218

Hallett, Andrew J., Placet, Emeline, Prieux, Roxane, McCafferty, Danielle, Platts, James A., Lloyd, David, Isaacs, Marc, Hayes, Anthony J., Coles, Simon J., Pitak, Mateusz B., Marchant, Sarah, Marriott, Stephen N., Allemann, Rudolf K., Dervisi, Athanasia and Fallis, Ian A. 2018. Exploring the cellular uptake and localisation of phosphorescent rhenium fac-tricarbonyl metallosurfactants as a function of lipophilicity. Dalton Transactions 47 (40) , pp. 14241-14253. 10.1039/C8DT00669E

Behiry, Enas M., Ruiz-Pernia, J. Javier, Luk, Louis, Tunon, Inaki, Moliner, Vicent and Allemann, Rudolf K. 2018. Isotope substitution of promiscuous alcohol dehydrogenase reveals the origin of substrate preference in the transition state. Angewandte Chemie International Edition 57 (12) , pp. 3128-3131. 10.1002/anie.201712826

Loizzi, Marianna, Gonzalez Gonzalez, Veronica, Miller, David J. and Allemann, Rudolf K. 2018. Nucleophilic water capture or proton loss: single amino acid switch converts δ-Cadinene synthase into germacradien-4-ol synthase. Chembiochem 19 (1) , pp. 100-105. 10.1002/cbic.201700531

Angelastro, Antonio, Dawson, William M., Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K. 2017. Chemoenzymatic assembly of isotopically labeled folates. Journal of the American Chemical Society 139 (37) , pp. 13047-13054. 10.1021/jacs.7b06358

Scott, Alan F., Luk, Louis Yu Pan and Allemann, Rudolf Konrad 2017. Chemical ligation and isotope labeling to locate dynamic effects. In: Imperiali, Barbara ed. Methods in Enzymology, Vol. 596. Elsevier, pp. 23-41. (10.1016/bs.mie.2017.06.040)

Hughes, Robert L., Johnson, Luke A., Behiry, Enas M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56 (15) , pp. 2126-2133. 10.1021/acs.biochem.7b00045

Tang, Xiaoping, Demiray, Melodi, Wirth, Thomas and Allemann, Rudolf Konrad 2017. Concise synthesis of artemisinin from a farnesyl diphosphate analogue. Bioorganic & Medicinal Chemistry 26 (7) , pp. 1314-1319. 10.1016/j.bmc.2017.03.068

Loveridge, Edric Joel, Hroch, Lukas, Hughes, Robert L., Williams, Thomas, Davies, Rhidian L., Angelastro, Antonio, Luk, Louis Yu Pan, Maglia, Giovanni and Allemann, Rudolf Konrad 2017. Reduction of folate by dihydrofolate reductase from thermotoga maritima. Biochemistry 56 (13) , pp. 1879-1886. 10.1021/acs.biochem.6b01268

Demiray, Melodi, Tang, Xiaoping, Wirth, Thomas, Faraldos, Juan A. and Allemann, Rudolf K. 2017. Effiziente chemoenzymatische Synthese von dhydroartemisinaldehyd. Angewandte Chemie 129 (15) , pp. 4411-4415. 10.1002/ange.201609557

Demiray, Melodi, Tang, Xiaoping, Wirth, Thomas, Faraldos, Juan A. and Allemann, Rudolf K. 2017. An efficient chemoenzymatic synthesis of dihydroartemisinic aldehyde. Angewandte Chemie International Edition 56 (15) , pp. 4347-4350. 10.1002/anie.201609557

Angelastro, Antonio, Dawson, William M., Luk, Louis Y. P. and Allemann, Rudolf K. 2017. A versatile disulfide-driven recycling system for NADP+ with high cofactor turnover number. ACS Catalysis 7 (2) , pp. 1025-1029. 10.1021/acscatal.6b03061

Tang, Xiaoping, Allemann, Rudolf Konrad and Wirth, Thomas 2017. Optimising terpene synthesis with flow biocatalysis. European Journal of Organic Chemistry 2017 (2) , pp. 414-418. 10.1002/ejoc.201601388

Faraldos, Juan, Grundy, Daniel, Cascon Salgado, Oscar, Leoni, Stefano, van der Kamp, Marc W and Allemann, Rudolf 2016. Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate. Chemical Communications 52 (97) , pp. 14027-14030. 10.1039/C6CC08164A

Mart, Robert and Allemann, Rudolf 2016. Azobenzene photocontrol of peptides and proteins. Chemical Communications 52 (83) , pp. 12262-12277. 10.1039/C6CC04004G

Gonzalez, Veronica, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf Konrad 2016. The amino-terminal segment in the β-domain of δ-cadinene synthase is essential for catalysis. Organic & Biomolecular Chemistry 14 (31) , pp. 7451-7454. 10.1039/C6OB01398H

Ruiz-Pernía, J. Javier, Behiry, Enas, Luk, Louis Yu Pan, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2016. Minimization of dynamic effects in the evolution of dihydrofolate reductase. Chemical Science 7 (5) , pp. 3248-3255. 10.1039/C5SC04209G

Chen, Mengbin, Chou, Wayne K. W., Al-Lami, Naeemah, Faraldos, Juan, Allemann, Rudolf, Cane, David E. and Christianson, David W. 2016. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry 55 (20) , pp. 2864-2874. 10.1021/acs.biochem.6b00343

Mart, Robert, Meah, Dilruba and Allemann, Rudolf Konrad 2016. Photocontrolled exposure of pro-apoptotic peptide sequences in LOV proteins modulate Bcl-2 family interactions. Chembiochem 17 (8) , pp. 698-701. 10.1002/cbic.201500469

Grundy, Daniel J., Chen, Mengbin, Gonzalez, Veronica, Leoni, Stefano, Miller, David James, Christianson, David W. and Allemann, Rudolf Konrad 2016. Mechanism of germacradien-4-ol synthase controlled water capture. Biochemistry 55 (14) , pp. 2112-2121. 10.1021/acs.biochem.6b00115

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2016. Pinpointing dynamic coupling in enzymes for efficient drug design. Future Science OA 2 (1) 10.4155/fsoa.2015.0017

Adams, S.E., Robinson, E.J., Miller, David James, Rizkallah, Pierre, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2015. Conformationally restricted calpain inhibitors. Chemical Science 6 (12) , pp. 6865-6871. 10.1039/c5sc01158b

Luk, Louis Y. P., Ruiz-Pernía, J. Javier, Adesina, Aduragbemi S., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vincent and Allemann, Rudolf K. 2015. Chemical ligation and isotope labeling to locate dynamic effects during catalysis by dihydrofolate reductase. Angewandte Chemie International Edition 54 (31) , pp. 9016-9020. 10.1002/anie.201503968

Touchet, Sabrina, Chamberlain, Keith, Woodcock, Christine M., Miller, David J., Birkett, Michael A., Pickett, John A. and Allemann, Rudolf K. 2015. Novel olfactory ligands via terpene synthases. Chemical Communications 51 (35) , pp. 7550-7553. 10.1039/C5CC01814E

Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2015. Protein motions and dynamic effects in enzyme catalysis. Physical Chemistry Chemical Physics 17 , pp. 30817-30827. 10.1039/C5CP00794A

Allemann, Rudolf Konrad, Loveridge, Edric and Luk, Louis Yu Pan 2015. Protein motions, dynamic effects and thermal stability in dihydrofolate reductase from the hyperthermophile thermotoga maritima. In: Olivares-Quiroz, Luis, Guzmán-López, Orlando and Jardón-Valadez, Hector Eduardo eds. Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation, Springer International Publishing, pp. 99-113. (10.1007/978-3-319-21687-4_6)

Luk, Louis Y. P., Ruiz-Pernia, J. Javier, Dawson, William M., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf K. 2014. Protein isotope effects in dihydrofolate reductase from Geobacillus stearothermophilus show entropic-enthalpic com-pensatory effects on the rate constant. Journal of the American Chemical Society 136 (49) , pp. 17317-17323. 10.1021/ja5102536

Gonzalez, Veronica, Touchet, Sabrina, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf K. 2014. Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-Germacrene A synthase. Journal of the American Chemical Society 136 (41) , pp. 14505-14512. 10.1021/ja5066366

Adams, Sarah Elizabeth, Rizkallah, Pierre, Miller, David James, Robinson, Emma J., Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2014. The structural basis of differential inhibition of human calpain by indole and phenyl α--mercaptoacrylic acids. Journal of Structural Biology 187 (3) , pp. 236-241. 10.1016/j.jsb.2014.07.004

Behiry, Enas Mamdouh, Evans, Rhiannon Mari, Guo, Jian Nan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Loop Interactions during Catalysis by Dihydrofolate Reductase from Moritella profunda. Biochemistry 53 (29) , pp. 4769-4774. 10.1021/bi500508z

Behiry, Enas Mamdouh, Luk, Louis Yu Pan, Matthews, Stella M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Role of the occluded conformation in bacterial dihydrofolate reductases. Biochemistry 53 (29) , pp. 4761-4768. 10.1021/bi500507v

Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K. 2014. Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases. Journal of the American Chemical Society 136 (19) , pp. 6862-6865. 10.1021/ja502673h

Guo, Jian Nan, Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Thermal adaptation of dihydrofolate reductase from the moderate thermophile geobacillus stearothermophilus. Biochemistry 53 (17) , pp. 2855-2863. 10.1021/bi500238q

Ruiz-Pernia, J. Javier, Luk, Louis Yu Pan, Garcia-Meseguer, Rafael, Martí, Sergio, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 135 (49) , pp. 18689-18696. 10.1021/ja410519h

Cascón, Oscar, Richter, Gerald, Allemann, Rudolf Konrad and Wirth, Thomas 2013. Efficient terpene synthase catalysis by extraction in flow. ChemPlusChem 78 (11) , pp. 1334-1337. 10.1002/cplu.201300303

Miller, David James, Adams, Sarah Elizabeth, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2013. Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future? Future Medicinal Chemistry 5 (17) , pp. 2057-2074. 10.4155/fmc.13.172

Luk, Louis Yu Pan, Ruiz-Pernia, J. Javier, Dawson, William Michael, Roca, Maite, Loveridge, Edric Joel, Glowacki, David R., Harvey, Jeremy N., Mulholland, Adrian J., Tunon, Inaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis. Proceedings of the National Academy of Sciences of the United States of America 110 (41) , pp. 16344-16349. 10.1073/pnas.1312437110

Mart, Robert J., Errington, Rachel Jane, Watkins, Catherine Louise, Chappell, Sally Claire, Wiltshire, Marie, Jones, Arwyn Tomos, Smith, Paul James and Allemann, Rudolf Konrad 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9 (11) , pp. 2597-2603. 10.1039/c3mb70246d

Guo, Jiannan, Loveridge, Edric Joel, Luk, Louis Yu Pan and Allemann, Rudolf Konrad 2013. Effect of dimerization on dihydrofolate reductase catalysis. Biochemistry 52 (22) , pp. 3881-3887. 10.1021/bi4005073

Loveridge, Edric Joel, Matthews, Stella M., Williams, Christopher, Whittaker, Sara B.-M., Günther, Ulrich L., Evans, Rhiannon M., Dawson, William Michael, Crump, Matthew P. and Allemann, Rudolf Konrad 2013. Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate. Biomolecular NMR Assignments 7 (1) , pp. 61-64. 10.1007/s12104-012-9378-x

Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2013. 1H, 13C and 15N chemical shift assignments of unliganded Bcl-xL and its complex with a photoresponsive Bak-derived peptide. Biomolecular NMR Assignments 7 (2) , pp. 187-191. 10.1007/s12104-012-9407-9

Li, Jian-Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang-Qing, Wang, Ling-Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao-Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from 'Artemisia annua': Product specificity and catalytic efficiency. Biochemical Journal 451 (3) , pp. 417-426. 10.1042/BJ20130041

Li, Jian‑Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang‑Qing, Wang, Ling‑Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao‑Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochemical Journal -London- 451 (3) , pp. 417-426. 10.1042/BJ20130041

Chen, Mengbin, Al-Lami, Naeemah, Janvier, Marine, D'Antonio, Edward L., Faraldos, Juan A., Cane, David E., Allemann, Rudolf Konrad and Christianson, David W. 2013. Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry 52 (32) , pp. 5441-5453. 10.1021/bi400691v

Pickett, John A., Allemann, Rudolf Konrad and Birkett, Michael A. 2013. The semiochemistry of aphids. Natural Product Reports 30 (10) , pp. 1277-1283. 10.1039/c3np70036d

van der Kamp, Marc W., Sirirak, Jitnapa, Zurek, Jolanta, Allemann, Rudolf Konrad and Mulholland, Adrian J. 2013. Conformational change and ligand binding in the aristolochene synthase catalytic cycle. Biochemistry 52 (45) , pp. 8094-8105. 10.1021/bi400898k

Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2012. NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL. Journal of the American Chemical Society 134 (18) , pp. 7644-7647. 10.1021/ja302390a

Aros Orellana, Danilo Fernando, Gonzalez, Veronica, Allemann, Rudolf Konrad, Müller, Carsten Theodor, Rosati, Carlo and Rogers, Hilary Joan 2012. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers. Journal of Experimental Botany 63 (7) , pp. 2739-2752. 10.1093/jxb/err456

Loveridge, Edric Joel, Behiry, Enas Mamdouh, Guo, Jian Nan and Allemann, Rudolf Konrad 2012. Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis. Nature Chemistry 4 (4) , pp. 292-297. 10.1038/nchem.1296

Miller, David James and Allemann, Rudolf Konrad 2012. Sesquiterpene synthases: Passive catalysts or active players? Natural Product Reports 29 (1) , pp. 60-71. 10.1039/c1np00060h

Mart, Robert J., Wysoczanski, Piotr, Kneissl, Sabine, Ricci, Antonio, Brancale, Andrea and Allemann, Rudolf Konrad 2012. Design of photocontrolled RNA-binding peptidomimetics. ChemBioChem 13 (4) , pp. 515-519. 10.1002/cbic.201100800

Faraldos, Juan A., Miller, David James, Gonzalez, Veronica, Yoosuf-Aly, Fathima Zulfa, Cascón, Oscar, Li, Amang and Allemann, Rudolf Konrad 2012. A 1,6-ring closure mechanism for (+)-δ-cadinene synthase? Journal of the American Chemical Society 134 (13) , pp. 5900-5908. 10.1021/ja211820p

Faraldos, Juan A., Gonzalez, Veronica and Allemann, Rudolf Konrad 2012. The role of aristolochene synthase in diphosphate activation. Chemical Communications- Royal Society of Chemistry 48 (26) , pp. 3230-3232. 10.1039/c2cc17588f

Adams, Sarah Elizabeth, Parr, Christian, Miller, David James, Allemann, Rudolf Konrad and Hallett, Maurice Bartlett 2012. Potent inhibition of Ca2+-dependent activation of calpain-1 by novel mercaptoacrylates. MedChemComm 3 (5) , pp. 566-570. 10.1039/c2md00280a

Yoosuf-Aly, Zulfa, Faraldos, Juan A., Miller, David James and Allemann, Rudolf Konrad 2012. Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate. Chemical Communications 48 , pp. 7040-7042. 10.1039/c2cc32883f

Cascón, Oscar, Touchet, Sabrina, Miller, David James, Gonzalez, Veronica, Faraldos, Juan A. and Allemann, Rudolf Konrad 2012. Chemoenzymatic preparation of germacrene analogues. Chemical Communications 48 (78) , pp. 9702-9704. 10.1039/c2cc35542f

Faraldos, Juan A., Gonzalez, Veronica, Li, Amang, Yu, Fanglei, Köksal, Mustafa, Christianson, David W. and Allemann, Rudolf Konrad 2012. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society 134 (51) , pp. 20844-20848. 10.1021/ja311022s

Loveridge, Edric Joel, Tey, Lai-Hock, Behiry, Enas Mamdouh, Dawson, William Michael, Evans, Rhiannon Mari, Whittaker, Sara B.-M., Günther, Ulrich L., Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2011. The role of large-scale motions in catalysis by dihydrofolate reductase. Journal of the American Chemical Society 133 (50) , pp. 20561-20570. 10.1021/ja208844j

Faraldos, Juan A., Antonczak, Alicja K., Gonzalez, Veronica, Fullerton, Rebecca, Tippmann, Eric Michael and Allemann, Rudolf Konrad 2011. Probing eudesmane cation−π interactions in catalysis by aristolochene synthase with non-canonical amino acids. Journal of the American Chemical Society 133 (35) , pp. 13906-13909. 10.1021/ja205927u

Fricke, Thomas, Mart, Robert J., Watkins, Catherine Louise, Wiltshire, Marie, Errington, Rachel Jane, Smith, Paul James, Jones, Arwyn Tomos and Allemann, Rudolf Konrad 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22 (9) , pp. 1763-1767. 10.1021/bc200338u

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2011. Effect of pH on Hydride Transfer by Escherichia coli Dihydrofolate Reductase. ChemBioChem 12 (8) , pp. 1258-1262. 10.1002/cbic.201000794

Faraldos, Juan A., Gonzalez, Veronica, Senske, Michael and Allemann, Rudolf Konrad 2011. Templating effects in aristolochene synthase catalysis: elimination versus cyclisation. Organic & Biomolecular Chemistry 9 (20) , pp. 6920-6923. 10.1039/c1ob06184d

Loveridge, Edric Joel, Dawson, William Michael, Evans, Rhiannon Mari, Sobolewska, Anna and Allemann, Rudolf Konrad 2011. Reduced Susceptibility of Moritella profunda Dihydrofolate Reductase to Trimethoprim is Not Due to Glutamate 28. The Protein Journal 30 (8) , pp. 546-548. 10.1007/s10930-011-9361-x

Faraldos, Juan A. and Allemann, Rudolf Konrad 2011. Inhibition of (+)-Aristolochene Synthase with Iminium Salts Resembling Eudesmane Cation. Organic Letters 13 (5) , pp. 1202-1205. 10.1021/ol2000843

Fricke, Thomas, Mart, Robert J., Watkins, Catherine Louise, Jones, Arwyn Tomos and Allemann, Rudolf Konrad 2010. Click chemistry for the generation of cell permeable apoptotic peptides. Drug Discovery Today 15 (23-24) , p. 1088. 10.1016/j.drudis.2010.09.375

Tey, Lai-Hock, Loveridge, Edric Joel, Swanwick, Richard, Flitsch, Sabine L. and Allemann, Rudolf Konrad 2010. Highly site-selective stability increases by glycosylation of dihydrofolate reductase. FEBS Journal 277 (9) , pp. 2171-2179. 10.1111/j.1742-4658.2010.07634.x

Edwards, Wayne Robert, Williams, Abigail J., Morris, Josephine Lydia, Baldwin, Amy Joy, Allemann, Rudolf Konrad and Jones, Darran Dafydd 2010. Regulation of β-Lactamase activity by remote binding of Heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49 (31) , pp. 6541-6549. 10.1021/bi100793y

Loveridge, Edric Joel, Tey, Lai-Hock and Allemann, Rudolf Konrad 2010. Solvent effects on catalysis by Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 132 (3) , pp. 1137-1143. 10.1021/ja909353c

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2010. The Temperature Dependence of the Kinetic Isotope Effects of Dihydrofolate Reductase from Thermotoga maritima Is Influenced by Intersubunit Interactions. Biochemistry 49 (25) , pp. 5390-5396. 10.1021/bi100761x

Evans, Rhiannon Mari, Behiry, Enas Mamdouh, Tey, Lai-Hock, Guo, Jiannan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2010. Catalysis by Dihydrofolate Reductase from the Psychropiezophile Moritella profunda. ChemBioChem 11 (14) , pp. 2010-2017. 10.1002/cbic.201000341

Faraldos, Juan A., Kariuki, Benson and Allemann, Rudolf Konrad 2010. Intermediacy of Eudesmane Cation during Catalysis by Aristolochene Synthase. Journal of Organic Chemistry 75 (4) , pp. 1119-1125. 10.1021/jo902397v

Loveridge, Edric Joel, Behiry, Enas Mamdouh, Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Different reaction mechanisms for mesophilic and thermophilic dihydrofolate reductases. Journal of the American Chemical Society 131 (20) , pp. 6926-6927. 10.1021/ja901441k

Allemann, Rudolf Konrad, Evans, Rhiannon Mari and Loveridge, Edric Joel 2009. Probing coupled motions in enzymatic hydrogen tunnelling reactions. Biochemical Society Transactions 37 , pp. 349-353. 10.1042/BST0370349

Loveridge, Edric Joel, Rodriguez, R. J., Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Effect of Dimerization on the Stability and Catalytic Activity of Dihydrofolate Reductase from the Hyperthermophile Thermotoga maritima. Biochemistry 48 (25) , pp. 5922-5933. 10.1021/bi900411a

Loveridge, Edric Joel, Maglia, Giovanni and Allemann, Rudolf Konrad 2009. The Role of Arginine 28 in Catalysis by Dihydrofolate Reductase from the HyperthermophileThermotoga maritima. ChemBioChem 10 (16) , pp. 2624-2627. 10.1002/cbic.200900465

Gennadios, Heather A., Gonzalez, Veronica, Di Costanzo, Luigi, Li, Amang, Yu, Fanglei, Miller, David James, Allemann, Rudolf Konrad and Christianson, David W. 2009. Crystal structure of (+)-δ-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry 48 (26) , pp. 6175-6183. 10.1021/bi900483b

Miller, David James, Yu, Fanglei, Knight, David William and Allemann, Rudolf Konrad 2009. 6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase. Organic & Biomolecular Chemistry 7 (5) , pp. 962-975. 10.1039/b817194g

Allemann, Rudolf Konrad 2009. Cystine-based Scaffolds for Functional Miniature Proteins. In: Moroder, L. and Buchner, J. eds. Oxidative Folding of Peptides and Proteins, London: RSC Publishing, pp. 381-395. (10.1039/9781847559265-00381)

Loveridge, Edric Joel and Allemann, Rudolf Konrad 2009. Direct methods for the analysis of quantum-mechanical tunnelling: dihydrofolate reductase. In: Allemann, Rudolf Konrad and Scrutton, N. S. eds. Quantum Tunnelling in Enzyme-Catalysed Reactions, London: RSC Publishing, pp. 179-198. (10.1039/9781847559975-00179)

Allemann, Rudolf Konrad, Young, Neil James, Ma, Shuhua, Truhlar, Donald G. and Gao, Jiali 2009. Synthetic Efficiency in Enzyme Mechanisms Involving Carbocations: Aristolochene Synthase [Addition/Correction]. Journal of the American Chemical Society 131 (27) , p. 9600. 10.1021/ja904281h

Hay, Sam, Evans, Rhiannon Mari, Levy, Colin, Loveridge, Edric Joel, Wang, Xi, Leys, David, Allemann, Rudolf Konrad and Scrutton, Nigel S. 2009. Are the Catalytic Properties of Enzymes from Piezophilic Organisms Pressure Adapted? ChemBioChem 10 (14) , pp. 2348-2353. 10.1002/cbic.200900367

Carpenter, Barry K. 2009. The transition-state theory description of enzyme catalysis for classically activated reactions. In: Allemann, Rudolf Konrad and Scrutton, N. S. eds. Quantum tunnelling in enzyme-catalysed reactions, London: RSC Publishing, pp. 1-17. (10.1039/9781847559975-00001)

Allemann, Rudolf Konrad and Scrutton, N. S., eds. 2009. Quantum tunnelling in enzyme-catalysed reactions. RSC biomolecular sciences, vol. 18. Cambridge: RSC Publishing.

Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2008. FLUO 14-Study of sesquiterpene cyclization reactions using fluorinated farnesyl diphosphate analogs. Abstracts of Papers of the American Chemical Society 236

Shishova, Ekaterina Y., Yu, Fanglei, Miller, David James, Faraldos, Juan A., Zhao, Yuxin X., Coates, Robert M., Allemann, Rudolf Konrad, Cane, David E. and Christianson, David W. 2008. X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. Journal of Biological Chemistry 283 (22) , pp. 15431-15439. 10.1074/jbc.M800659200

Loveridge, Edric Joel, Evans, R. M. and Allemann, Rudolf Konrad 2008. Solvent Effects on Environmentally Coupled Hydrogen Tunnelling During Catalysis by Dihydrofolate Reductase from Thermotoga maritima. Chemistry-a European Journal 14 (34) , pp. 10782-10788. 10.1002/chem.200801804

Allemann, Rudolf Konrad 2008. Chemical wizardry? The generation of diversity in terpenoid biosynthesis. Pure and Applied Chemistry 80 (8) , pp. 1791-1798. 10.1351/pac200880081791

Edwards, W. R., Busse, K., Allemann, Rudolf Konrad and Jones, Darran Dafydd 2008. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research 36 (13) 10.1093/nar/gkn363

Fütterer, K., Ravelli, R. B. G., White, S. A., Nicoll, A. J. and Allemann, Rudolf Konrad 2008. Differential specific radiation damage in the CuII-bound and PdII-bound forms of an α-helical foldamer: A case study of crystallographic phasing by RIP and SAD. Acta Crystallographica Section D: Biological Crystallography 64 (3) , pp. 264-272. 10.1107/S0907444907065948

Hay, S., Pang, J. Y., Monaghan, P. J., Wang, X., Evans, R. M., Sutcliffe, M. J., Allemann, Rudolf Konrad and Scrutton, N. S. 2008. Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions. ChemPhysChem 9 (11) , pp. 1536-1539. 10.1002/cphc.200800291

Miller, David James, Gao, Jiali, Truhlar, D. G., Young, Neil James, Gonzalez, Veronica and Allemann, Rudolf Konrad 2008. Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti. Organic & Biomolecular Chemistry 6 (13) , pp. 2346-2354. 10.1039/b804198a

Kneissl, Sabine, Loveridge, Edric Joel, Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2008. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL. ChemBioChem 9 (18) , pp. 3046-3054. 10.1002/cbic.200800502

Yu, Fanglei, Miller, David James and Allemann, Rudolf Konrad 2007. Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate. Chemical Communications- Royal Society of Chemistry (40) , pp. 4155-4157. 10.1039/b709562g

Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2007. Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A. Chembiochem 8 (15) , pp. 1819-1825. 10.1002/cbic.200700219

Miller, David James, Yu, Fanglei, Young, Neil J and Allemann, Rudolf Konrad 2007. Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity. Organic & Biomolecular Chemistry 5 (20) , pp. 3287-3298. 10.1039/b713301b

Miller, D. J. and Allemann, Rudolf Konrad 2007. myo-Inositol Monophosphatase: A Challenging Target for Mood Stabilising Drugs. Mini-Reviews in Chemistry 7 (2) , pp. 107-113. 10.2174/138955707779802624

Pang, Jiayun and Allemann, Rudolf Konrad 2007. Molecular dynamics simulation of thermal unfolding of Thermatoga maritima DHFR. Physical Chemistry Chemical Physics 9 (6) , pp. 711-718. 10.1039/b611210b

Allemann, Rudolf Konrad, Young, Neil James, Ma, Shuhua, Truhlar, Donald G. and Gao, Jiali 2007. Synthetic Efficiency in Enzyme Mechanisms Involving Carbocations:  Aristolochene Synthase. Journal of the American Chemical Society 129 (43) , pp. 13008-13013. 10.1021/ja0722067

Nicoll, Andrew J., Miller, David James, Fütterer, Klaus, Ravelli, Raymond and Allemann, Rudolf Konrad 2006. Designed high affinity Cu2+ -Binding α-Helical foldamer. Journal of the American Chemical Society 128 (28) , pp. 9187-9193. 10.1021/ja061513u

Allemann, Rudolf Konrad, Evans, Rhiannon Mari, Tey, Lai-Hock, Maglia, G., Pang, Jiayun, Rodriguez, Robert, Shrimpton, P. J. and Swanwick, Richard S. 2006. Protein motions during catalysis by dihydrofolate reductases. Philosophical Transactions of the Royal Society of London Series B - Biological Sciences 361 (1472) , pp. 1317-1321. 10.1098/rstb.2006.1865

Maglia, Giovanni, Swanwick, Richard S., Tey, Lai-Hock and Allemann, Rudolf Konrad 2006. Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase. Biochemical Journal 394 (1) , pp. 259-265. 10.1042/BJ20051464

Pang, Jiayun, Pu, Jingzhi, Gao, Jiali, Truhlar, Donald G. and Allemann, Rudolf Konrad 2006. Hydride Transfer Reaction Catalyzed by Hyperthermophilic Dihydrofolate Reductase Is Dominated by Quantum Mechanical Tunneling and Is Promoted by Both Inter- and Intramonomeric Correlated Motions. Journal of the American Chemical Society 128 (24) , pp. 8015-8023. 10.1021/ja061585l

Forcat, Silvia and Allemann, Rudolf Konrad 2006. Stabilisation of transition states prior to and following eudesmane cation in aristolochene synthase. Organic & Biomolecular Chemistry 4 (13) , pp. 2563-2567. 10.1039/b604147g

Guerrero, Lucia, Smart, Oliver S., Weston, Chris J., Allemann, Rudolf Konrad and Woolley, G. Andrew 2005. Photochemical Regulation of DNA-Binding Specificity of MyoD. Angewandte Chemie International Edition 44 (47) , pp. 7778-7782. 10.1002/anie.200502666

Swanwick, Richard S., Daines, Alison M., Flitsch, Sabine L. and Allemann, Rudolf Konrad 2005. Synthesis of homogenous site-selectively glycosylated proteins. Organic & Biomolecular Chemistry 3 (4) , pp. 572-574. 10.1039/b417133k

Swanwick, Richard S., Daines, Alison M., Tey, Lai-Hock, Flitsch, Sabine L. and Allemann, Rudolf Konrad 2005. Increased Thermal Stability of Site-Selectively Glycosylated Dihydrofolate Reductase. ChemBioChem 6 (8) , pp. 1338-1340. 10.1002/cbic.200500103

Guerrero, Lucia, Smart, Oliver S., Woolley, G. Andrew and Allemann, Rudolf Konrad 2005. Photocontrol of DNA Binding Specificity of a Miniature Engrailed Homeodomain. Journal of the American Chemical Society 127 (44) , pp. 15624-15629. 10.1021/ja0550428

Swanwick, Richard S., Shrimpton, Paul J. and Allemann, Rudolf Konrad 2004. Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished datalytic performance. Biochemistry 43 (14) , pp. 4119-4127. 10.1021/bi036164k

Miller, David James, Bashir-Uddin Surfraz, M., Akhtar, Mahmoud, Gani, David and Allemann, Rudolf Konrad 2004. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity. Organic & Biomolecular Chemistry 2 (5) , pp. 671-688. 10.1039/b312808c

Turner, Elizebeth C., Cureton, Charlotte H., Weston, Chris J., Smart, Oliver S. and Allemann, Rudolf Konrad 2004. Controlling the DNA Binding Specificity of bHLH Proteins through Intramolecular Interactions. Chemistry & Biology 11 (1) , pp. 69-77. 10.1016/j.chembiol.2003.12.015

Nicoll, Andrew J. and Allemann, Rudolf Konrad 2004. Nucleophilic and general acid catalysis at physiological pH by a designed miniature esterase. Organic & Biomolecular Chemistry 2 (15) , pp. 2175-2180. 10.1039/b404730c

Bashir-Uddin Surfraz, M., Akhtar, Mahmoud and Allemann, Rudolf Konrad 2004. Bis-benzyl protected 6-amino cyclitols are poisonous to Pd/C catalysed hydrogenolysis of benzyl ethers. Tetrahedron Letters 45 (6) , pp. 1223-1226. 10.1016/j.tetlet.2003.11.130

Weston, Chris J., Cureton, Charly H., Calvert, Melanie J., Smart, Oliver S. and Allemann, Rudolf Konrad 2004. A Stable Miniature Protein with Oxaloacetate Decarboxylase Activity. ChemBioChem 5 (8) , pp. 1075-1080. 10.1002/cbic.200300805

Forcat, Silvia and Allemann, Rudolf Konrad 2004. Dual role for phenylalanine 178 during catalysis by aristolochene synthase. Chemical Communications (18) , pp. 2094-2095. 10.1039/b407932a

Nicoll, Andrew J. and Allemann, Rudolf Konrad 2004. Miniature proteomics: designing alpha-helical miniature proteins. Recent Research Developments in Chemistry 2 , pp. 227-243.

Allemann, Rudolf Konrad and Maglia, Giovanni 2003. Evidence for Environmentally Coupled Hydrogen Tunneling during Dihydrofolate Reductase Catalysis. Journal of the American Chemical Society 125 (44) , pp. 13372-13373. 10.1021/ja035692g

Bashir-Uddin Surfraz, M., Miller, David James., Gani, David and Allemann, Rudolf Konrad 2003. Product-like inhibitors of inositol monophosphatase. Tetrahedron Letters 44 (41) , pp. 7677-7679. 10.1016/S0040-4039(03)01878-1

Maglia, Giovanni, Javed, Masood H. and Allemann, Rudolf Konrad 2003. Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima. Biochemical Journal 374 (2) , pp. 529-535. 10.1042/BJ20030412

Deligeorgopoulou, Athina, Taylor, Susan E., Forcat, Silvia and Allemann, Rudolf Konrad 2003. Stabilisation of eudesmane cation by tryptophan 334 during aristolochene synthase catalysis. Chemical Communications (17) , pp. 2162-2163. 10.1039/b306867f

Shrimpton, Paul, Mullaney, Alex and Allemann, Rudolf Konrad 2003. Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductase. Proteins: Structure, Function and Bioinformatics 51 (2) , pp. 216-223. 10.1002/prot.10370

Calvert, Melanie J., Ashton, Peter R. and Allemann, Rudolf Konrad 2002. Germacrene A Is a Product of the Aristolochene Synthase-Mediated Conversion of Farnesylpyrophosphate to Aristolochene. Journal of the American Chemical Society 124 (39) , pp. 11636-11641. 10.1021/ja020762p

Kohler, Ursina and Allemann, Rudolf Konrad 2002. Transcription factors. In: Creighton, T. E. ed. Encyclopedia of Molecular Biology, Oxford: Wiley, (10.1002/047120918X.emb1569)

Shrimpton, Paul and Allemann, Rudolf Konrad 2002. Role of water in the catalytic cycle of E. coli dihydrofolate reductase. Protein Science 11 (6) , pp. 1442-1451. 10.1110/ps.5060102

Calvert, Melanie J., Taylor, Susan E. and Allemann, Rudolf Konrad 2002. Tyrosine 92 of aristolochene synthase directs cyclisation of farnesyl pyrophosphate. Chemical Communications (20) , pp. 2384-2385. 10.1039/b206517g

Taylor, Susan E., Rutherford, Trevor J. and Allemann, Rudolf Konrad 2002. Design of a folded, conformationally stable oxaloacetate decarboxylase. Journal of the Chemical Society, Perkin Transactions 2 2 (4) , pp. 751-755. 10.1039/b200057c

Taylor, Susan E., Rutherford, Trevor J. and Allemann, Rudolf Konrad 2001. Design, synthesis and characterisation of a peptide with oxaloacetate decarboxylase activity. Biorganic and Medicinal Chemistry Letters 11 (19) , pp. 2631-2635. 10.1016/S0960-894X(01)00519-4

Dezan, C., Meierhans, D., Künne, A. G. E. and Allemann, Rudolf Konrad 1999. Acquisition of myogenic specificity through replacement of one amino acid of MASH-1 and introduction of an additional α-helical turn. Biological Chemistry 380 (6) , pp. 705-710. 10.1515/BC.1999.088

Allemann, Rudolf Konrad 1999. DNA-protein binding specificity. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 2. New York: Wiley, pp. 743-745.

Allemann, Rudolf Konrad 1999. DNA-protein interaction thermodynamics. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 2. New York: Wiley, pp. 745-755.

Allemann, Rudolf Konrad 1999. MADS-Box proteins. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 3. New York: Wiley, pp. 1430-1431.

Allemann, Rudolf Konrad 1999. Transcription factors. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 4. New York: Wiley, pp. 2586-2593.

Sieber, M. and Allemann, Rudolf Konrad 1998. Single chain dimers of MASH-1 bind DNA with enhanced affinity. Nucleic Acids Research 26 (6) , pp. 1408-1413. 10.1093/nar/26.6.1408

Künne, Andreas G. E., Sieber, Martin, Meierhans, Daniel and Allemann, Rudolf Konrad 1998. Thermodynamics of the DNA binding reaction of transcription factor MASH-1. Biochemistry 37 (12) , pp. 4217-4223. 10.1021/bi9725374

Meierhans, D. and Allemann, Rudolf Konrad 1998. The N-terminal methionine is a major determinant of the DNA binding specificity of MEF-2C. Journal of Biological Chemistry 273 (40) , pp. 26052-26060. 10.1074/jbc.273.40.26052

Sieber, M. and Allemann, Rudolf Konrad 1998. Arginine (348) is a major determinant of the DNA binding specificity of transcription factor E12. Biological Chemistry 379 (6) , pp. 731-735.

Meierhans, D. and Allemann, Rudolf Konrad 1997. High level expression in soluble form, one step purification, and characterization of the DNA binding domain of MEF-2C. Protein Expression and Purification 11 (3) , pp. 297-303. 10.1006/prep.1997.0795

Meierhans, D., Sieber, M. and Allemann, Rudolf Konrad 1997. High affinity binding of MEF-2C correlates with DNA bending. Nucleic Acids Research 25 (22) , pp. 4537-4544. 10.1093/nar/25.22.4537

Künne, Andreas G. E. and Allemann, Rudolf Konrad 1997. Covalently linking BHLH subunits of MASH-1 increases specificity of DNA Binding. Biochemistry 36 (5) , pp. 1085-1091. 10.1021/bi962185l

Allemann, Rudolf Konrad and Egli, M. 1997. DNA recognition and bending. Chemistry & Biology 4 (9) , pp. 643-650. 10.1016/S1074-5521(97)90218-0

Künne, A, Meierhans, D. and Allemann, Rudolf Konrad 1996. Basic helix-loop-helix protein MyoD displays modest DNA binding specificity. FEBS Letters 391 (1-2) , pp. 79-83. 10.1016/0014-5793(96)00707-7

Meierhans, Daniel, el-Ariss, Chirine, Neuenschwander, Margrit, Sieber, Martin, Stackhouse, Joseph F. and Allemann, Rudolf Konrad 1995. DNA Binding Specificity of the Basic-Helix-Loop-Helix Protein MASH-1. Biochemistry 34 (35) , pp. 11026-11036. 10.1021/bi00035a008

Johnsson, Kai, Allemann, Rudolf Konrad, Widmer, Hans and Benner, Steven A. 1993. Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides. Nature 365 (6446) , pp. 530-532. 10.1038/365530a0

Whiting, J., Marshall, H., Cook, M., Krumlauf, R., Rigby, P. W., Stott, D. and Allemann, Rudolf Konrad 1991. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes & Development 5 (11) , pp. 2048-2059. 10.1101/gad.5.11.2048

Hunt, P., Whiting, J., Nonchev, S., Sham, M.-H., Marshall, H., Graham, A., Allemann, Rudolf Konrad, Rigby, P., Gulisano, M., Faiella, A., Boncinelli, E. and Krumlauf, R. 1991. The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution. Development 113 (S2) , pp. 63-77.

Johnson, K., Allemann, Rudolf Konrad and Benner, S. A. 1990. Designed enzymes. In: Bleasdale, C. and Golding, R. eds. Molecular mechanisms in bioorganic processes, London: Royal Society of Chemistry, pp. 166-187.

Benner, Steven A. and Allemann, Rudolf Konrad 1989. The return of pancreatic ribonucleases. Trends in Biochemical Sciences 14 (10) , pp. 396-397. 10.1016/0968-0004(89)90282-X

Allemann, Rudolf Konrad, Hung, Rebecca and Benner, Steven A. 1988. Stereochemical profile of the dehydrogenases of Drosophila melanogaster. Journal of the American Chemical Society 110 (16) , pp. 5555-5560. 10.1021/ja00224a046

Benner, S. A. and Allemann, Rudolf Konrad 1987. Natural Selection, Protein Engineering, and the last Riboorganism: Rational Model Building in Biochemistry. Evolution of Catalytic Function, CSH Symposia on Quantitative Biology, vol. 52. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, pp. 53-63.