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Srivastava, Prabhakar L., Escorcia, Andrés M., Huynh, Florence, Miller, David J., Allemann, Rudolf K. and van der Kamp, Marc W.
2021.
Redesigning the molecular choreography to prevent hydroxylation in Germacradien-11-ol synthase catalysis.
ACS Catalysis
11
(3)
, 1033–1041.
10.1021/acscatal.0c04647
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Huynh, Florence, Tailby, Matthew, Finniear, Aled, Stephens, Kevin, Allemann, Rudolf K. and Wirth, Thomas
2020.
Accelerating biphasic biocatalysis through new process windows.
Angewandte Chemie International Edition
59
(38)
, pp. 16490-16495.
10.1002/anie.202005183
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Elsherbini, Mohamed, Huynh, Florence, Dunbabin, Alice, Allemann, Rudolf and Wirth, Thomas
2020.
Selective hydroboration - oxidation of terminal alkenes under flow conditions.
Chemistry - A European Journal
26
(50)
, pp. 11423-11425.
10.1002/chem.202001650
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Adesina, Aduragbemi S., Swiderek, Katarzyna, Luk, Louis Y. P., Moliner, Vicent and Allemann, Rudolf K.
2020.
Electric field measurements reveal the pivotal role of Cofactor-Substrate interaction in dihydrofolate reductase catalysis.
ACS Catalysis
10
(14)
, pp. 7907-7914.
10.1021/acscatal.0c01856
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Johnson, Luke A., Dunbabin, Alice, Benton, Jennifer C. R., Mart, Robert J. and Allemann, Rudolf K. 2020. Modular chemoenzymatic synthesis of terpenes and their analogues. Angewandte Chemie International Edition 59 (22) , pp. 8486-8490. 10.1002/anie.202001744 |
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Valikhani, Donya, Srivastava, Prabhakar L., Allemann, Rudolf K. and Wirth, Thomas 2020. Immobilised enzymes for sesquiterpene synthesis in batch and flow systems. ChemCatChem 12 (8) , pp. 2194-22197. 10.1002/cctc.201902135 |
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Day, Adam H., Ubler, Martin H., Best, Hannah L., Lloyd-Evans, Emyr, Mart, Robert J., Fallis, Ian A., Allemann, Rudolf K., Al-Wattar, Eman A. H., Keymer, Nathaniel I., Buurma, Niklaas J. and Pope, Simon J. A.
2020.
Targeted cell imaging properties of a deep red luminescent iridium(III) complex conjugated with a c-Myc signal peptide.
Chemical Science
11
(6)
, pp. 1599-1606.
10.1039/C9SC05568A
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Cresser-Brown, Joel, Rizkallah, Pierre, Jin, Yi, Roth, Christian, Miller, David J. and Allemann, Rudolf K.
2020.
An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq.
Acta Crystallographica Section F: Structural Biology Communications
76
(2)
, pp. 81-85.
10.1107/S2053230X20001181
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Allemann, Rudolf K, Scott, Alan F., Luk, Louis Y.-P., Tuñón, Iñaki and Moliner, Vicent
2019.
Heavy enzymes and the rational redesign of protein catalysts.
ChemBioChem
20
(22)
, pp. 2807-2812.
10.1002/cbic.201900134
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Angelastro, Antonio, Ruiz-Pernía, J. Javier, Tuñón, Iñaki, Moliner, Vicent, Luk, Louis Y. P. and Allemann, Rudolf K.
2019.
Loss of hyperconjugative effects drives hydride transfer during dihydrofolate reductase catalysis.
ACS Catalysis
9
(11)
, pp. 10343-10349.
10.1021/acscatal.9b02839
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Elsherbini, Mohamed, Allemann, Rudolf K. and Wirth, Thomas 2019. 'Dark' singlet oxygen made easy. Chemistry - A European Journal 25 (54) , pp. 12486-12490. 10.1002/chem.201903505 |
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Demiray, Melodi, Miller, David J and Allemann, Rudolf K
2019.
Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids.
Beilstein Journal of Organic Chemistry
15
, pp. 2184-2190.
10.3762/bjoc.15.215
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Scott, Alan F., Cresser-Brown, Joel, Williams, Thomas L., Rizkallah, Pierre J., Jin, Yi, Luk, Louis Y.-P. and Allemann, Rudolf K. 2019. Crystal structure and biophysical analysis of furfural detoxifying aldehyde reductase from clostridium beijerinkii. Applied and Environmental Microbiology 10.1128/AEM.00978-19 |
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Ruiz-Pernía, J. Javier, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf K.
2019.
Why are some enzymes dimers? flexibility and catalysis in Thermotoga maritima dihydrofolate reductase.
ACS Catalysis
9
, pp. 5902-5911.
10.1021/acscatal.9b01250
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Patel, Sanjay G., Sayers, Edward J., He, Lin, Narayan, Rohan, Williams, Thomas L., Mills, Emily M., Allemann, Rudolf K., Luk, Louis Y. P., Jones, Arwyn T. and Tsai, Yu-Hsuan
2019.
Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines.
Scientific Reports
9
(1)
, -.
10.1038/s41598-019-42456-8
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Loizzi, Marianna, Miller, David J. and Allemann, Rudolf K.
2019.
Silent catalytic promiscuity in the high-fidelity
terpene cyclase δ-cadinene synthase.
Organic & Biomolecular Chemistry
17
(5)
, pp. 1206-1214.
10.1039/C8OB02821D
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Kalash, Leen, Cresser-Brown, Joel, Habchi, Johnny, Morgan, Connor, Miller, David J., Glen, Robert C., Allemann, Rudolf K. and Bender, Andreas 2018. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space. European Journal of Medicinal Chemistry 157 , pp. 1264-1275. 10.1016/j.ejmech.2018.08.049 |
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Huynh, Florence, Grundy, Daniel J., Jenkins, Robert L., Miller, David J. and Allemann, Rudolf K. 2018. Sesquiterpene synthase-catalysed formation of a new medium-sized cyclic terpenoid ether from farnesyl diphosphate analogues. Chembiochem 19 (17) , pp. 1834-1838. 10.1002/cbic.201800218 |
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Hallett, Andrew J., Placet, Emeline, Prieux, Roxane, McCafferty, Danielle, Platts, James A., Lloyd, David, Isaacs, Marc, Hayes, Anthony J., Coles, Simon J., Pitak, Mateusz B., Marchant, Sarah, Marriott, Stephen N., Allemann, Rudolf K., Dervisi, Athanasia and Fallis, Ian A. 2018. Exploring the cellular uptake and localisation of phosphorescent rhenium fac-tricarbonyl metallosurfactants as a function of lipophilicity. Dalton Transactions 47 (40) , pp. 14241-14253. 10.1039/C8DT00669E |
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Behiry, Enas M., Ruiz-Pernia, J. Javier, Luk, Louis, Tunon, Inaki, Moliner, Vicent and Allemann, Rudolf K.
2018.
Isotope substitution of promiscuous alcohol dehydrogenase reveals the origin of substrate preference in the transition state.
Angewandte Chemie International Edition
57
(12)
, pp. 3128-3131.
10.1002/anie.201712826
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Loizzi, Marianna, Gonzalez Gonzalez, Veronica, Miller, David J. and Allemann, Rudolf K.
2018.
Nucleophilic water capture or proton loss: single amino acid switch converts δ-Cadinene synthase into germacradien-4-ol synthase.
Chembiochem
19
(1)
, pp. 100-105.
10.1002/cbic.201700531
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Angelastro, Antonio, Dawson, William M., Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K.
2017.
Chemoenzymatic assembly of isotopically labeled folates.
Journal of the American Chemical Society
139
(37)
, pp. 13047-13054.
10.1021/jacs.7b06358
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Scott, Alan F., Luk, Louis Yu Pan and Allemann, Rudolf Konrad 2017. Chemical ligation and isotope labeling to locate dynamic effects. In: Imperiali, Barbara ed. Methods in Enzymology, Vol. 596. Elsevier, pp. 23-41. (10.1016/bs.mie.2017.06.040) |
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Hughes, Robert L., Johnson, Luke A., Behiry, Enas M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2017. A rapid analysis of variations in conformational behavior during dihydrofolate reductase catalysis. Biochemistry 56 (15) , pp. 2126-2133. 10.1021/acs.biochem.7b00045 |
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Tang, Xiaoping, Demiray, Melodi, Wirth, Thomas and Allemann, Rudolf Konrad 2017. Concise synthesis of artemisinin from a farnesyl diphosphate analogue. Bioorganic & Medicinal Chemistry 26 (7) , pp. 1314-1319. 10.1016/j.bmc.2017.03.068 |
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Loveridge, Edric Joel, Hroch, Lukas, Hughes, Robert L., Williams, Thomas, Davies, Rhidian L., Angelastro, Antonio, Luk, Louis Yu Pan, Maglia, Giovanni and Allemann, Rudolf Konrad 2017. Reduction of folate by dihydrofolate reductase from thermotoga maritima. Biochemistry 56 (13) , pp. 1879-1886. 10.1021/acs.biochem.6b01268 |
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Demiray, Melodi, Tang, Xiaoping, Wirth, Thomas, Faraldos, Juan A. and Allemann, Rudolf K. 2017. Effiziente chemoenzymatische Synthese von dhydroartemisinaldehyd. Angewandte Chemie 129 (15) , pp. 4411-4415. 10.1002/ange.201609557 |
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Demiray, Melodi, Tang, Xiaoping, Wirth, Thomas, Faraldos, Juan A. and Allemann, Rudolf K.
2017.
An efficient chemoenzymatic synthesis of dihydroartemisinic aldehyde.
Angewandte Chemie International Edition
56
(15)
, pp. 4347-4350.
10.1002/anie.201609557
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Angelastro, Antonio, Dawson, William M., Luk, Louis Y. P. and Allemann, Rudolf K.
2017.
A versatile disulfide-driven recycling system for NADP+ with high cofactor turnover number.
ACS Catalysis
7
(2)
, pp. 1025-1029.
10.1021/acscatal.6b03061
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Tang, Xiaoping, Allemann, Rudolf Konrad and Wirth, Thomas 2017. Optimising terpene synthesis with flow biocatalysis. European Journal of Organic Chemistry 2017 (2) , pp. 414-418. 10.1002/ejoc.201601388 |
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Faraldos, Juan, Grundy, Daniel, Cascon Salgado, Oscar, Leoni, Stefano, van der Kamp, Marc W and Allemann, Rudolf 2016. Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate. Chemical Communications 52 (97) , pp. 14027-14030. 10.1039/C6CC08164A |
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Mart, Robert and Allemann, Rudolf 2016. Azobenzene photocontrol of peptides and proteins. Chemical Communications 52 (83) , pp. 12262-12277. 10.1039/C6CC04004G |
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Gonzalez, Veronica, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf Konrad 2016. The amino-terminal segment in the β-domain of δ-cadinene synthase is essential for catalysis. Organic & Biomolecular Chemistry 14 (31) , pp. 7451-7454. 10.1039/C6OB01398H |
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Ruiz-Pernía, J. Javier, Behiry, Enas, Luk, Louis Yu Pan, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2016. Minimization of dynamic effects in the evolution of dihydrofolate reductase. Chemical Science 7 (5) , pp. 3248-3255. 10.1039/C5SC04209G |
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Chen, Mengbin, Chou, Wayne K. W., Al-Lami, Naeemah, Faraldos, Juan, Allemann, Rudolf, Cane, David E. and Christianson, David W. 2016. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry 55 (20) , pp. 2864-2874. 10.1021/acs.biochem.6b00343 |
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Mart, Robert, Meah, Dilruba and Allemann, Rudolf Konrad 2016. Photocontrolled exposure of pro-apoptotic peptide sequences in LOV proteins modulate Bcl-2 family interactions. Chembiochem 17 (8) , pp. 698-701. 10.1002/cbic.201500469 |
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Grundy, Daniel J., Chen, Mengbin, Gonzalez, Veronica, Leoni, Stefano, Miller, David James, Christianson, David W. and Allemann, Rudolf Konrad 2016. Mechanism of germacradien-4-ol synthase controlled water capture. Biochemistry 55 (14) , pp. 2112-2121. 10.1021/acs.biochem.6b00115 |
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Loveridge, Edric Joel and Allemann, Rudolf Konrad
2016.
Pinpointing dynamic coupling in enzymes for efficient drug design.
Future Science OA
2
(1)
10.4155/fsoa.2015.0017
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Adams, S.E., Robinson, E.J., Miller, David James, Rizkallah, Pierre, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2015. Conformationally restricted calpain inhibitors. Chemical Science 6 (12) , pp. 6865-6871. 10.1039/c5sc01158b |
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Luk, Louis Y. P., Ruiz-Pernía, J. Javier, Adesina, Aduragbemi S., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vincent and Allemann, Rudolf K.
2015.
Chemical ligation and isotope labeling to locate dynamic effects during catalysis by dihydrofolate reductase.
Angewandte Chemie International Edition
54
(31)
, pp. 9016-9020.
10.1002/anie.201503968
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Touchet, Sabrina, Chamberlain, Keith, Woodcock, Christine M., Miller, David J., Birkett, Michael A., Pickett, John A. and Allemann, Rudolf K.
2015.
Novel olfactory ligands via terpene synthases.
Chemical Communications
51
(35)
, pp. 7550-7553.
10.1039/C5CC01814E
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Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2015. Protein motions and dynamic effects in enzyme catalysis. Physical Chemistry Chemical Physics 17 , pp. 30817-30827. 10.1039/C5CP00794A |
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Allemann, Rudolf Konrad, Loveridge, Edric and Luk, Louis Yu Pan 2015. Protein motions, dynamic effects and thermal stability in dihydrofolate reductase from the hyperthermophile thermotoga maritima. In: Olivares-Quiroz, Luis, Guzmán-López, Orlando and Jardón-Valadez, Hector Eduardo eds. Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation, Springer International Publishing, pp. 99-113. (10.1007/978-3-319-21687-4_6) |
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Luk, Louis Y. P., Ruiz-Pernia, J. Javier, Dawson, William M., Loveridge, E. Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf K.
2014.
Protein isotope effects in dihydrofolate reductase from Geobacillus stearothermophilus show entropic-enthalpic com-pensatory effects on the rate constant.
Journal of the American Chemical Society
136
(49)
, pp. 17317-17323.
10.1021/ja5102536
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Gonzalez, Veronica, Touchet, Sabrina, Grundy, Daniel J., Faraldos, Juan A. and Allemann, Rudolf K.
2014.
Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-Germacrene A synthase.
Journal of the American Chemical Society
136
(41)
, pp. 14505-14512.
10.1021/ja5066366
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Adams, Sarah Elizabeth, Rizkallah, Pierre, Miller, David James, Robinson, Emma J., Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2014. The structural basis of differential inhibition of human calpain by indole and phenyl α--mercaptoacrylic acids. Journal of Structural Biology 187 (3) , pp. 236-241. 10.1016/j.jsb.2014.07.004 |
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Behiry, Enas Mamdouh, Evans, Rhiannon Mari, Guo, Jian Nan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Loop Interactions during Catalysis by Dihydrofolate Reductase from Moritella profunda. Biochemistry 53 (29) , pp. 4769-4774. 10.1021/bi500508z |
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Behiry, Enas Mamdouh, Luk, Louis Yu Pan, Matthews, Stella M., Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Role of the occluded conformation in bacterial dihydrofolate reductases. Biochemistry 53 (29) , pp. 4761-4768. 10.1021/bi500507v |
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Luk, Louis Y. P., Loveridge, E. Joel and Allemann, Rudolf K.
2014.
Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases.
Journal of the American Chemical Society
136
(19)
, pp. 6862-6865.
10.1021/ja502673h
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Guo, Jian Nan, Luk, Louis Yu Pan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2014. Thermal adaptation of dihydrofolate reductase from the moderate thermophile geobacillus stearothermophilus. Biochemistry 53 (17) , pp. 2855-2863. 10.1021/bi500238q |
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Ruiz-Pernia, J. Javier, Luk, Louis Yu Pan, Garcia-Meseguer, Rafael, Martí, Sergio, Loveridge, Edric Joel, Tuñón, Iñaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Increased dynamic effects in a catalytically compromised variant of Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 135 (49) , pp. 18689-18696. 10.1021/ja410519h |
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Cascón, Oscar, Richter, Gerald, Allemann, Rudolf Konrad and Wirth, Thomas 2013. Efficient terpene synthase catalysis by extraction in flow. ChemPlusChem 78 (11) , pp. 1334-1337. 10.1002/cplu.201300303 |
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Miller, David James, Adams, Sarah Elizabeth, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2013. Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future? Future Medicinal Chemistry 5 (17) , pp. 2057-2074. 10.4155/fmc.13.172 |
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Luk, Louis Yu Pan, Ruiz-Pernia, J. Javier, Dawson, William Michael, Roca, Maite, Loveridge, Edric Joel, Glowacki, David R., Harvey, Jeremy N., Mulholland, Adrian J., Tunon, Inaki, Moliner, Vicent and Allemann, Rudolf Konrad 2013. Unraveling the role of protein dynamics in dihydrofolate reductase catalysis. Proceedings of the National Academy of Sciences of the United States of America 110 (41) , pp. 16344-16349. 10.1073/pnas.1312437110 |
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Mart, Robert J., Errington, Rachel Jane, Watkins, Catherine Louise, Chappell, Sally Claire, Wiltshire, Marie, Jones, Arwyn Tomos, Smith, Paul James and Allemann, Rudolf Konrad 2013. BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells. Molecular BioSystems 9 (11) , pp. 2597-2603. 10.1039/c3mb70246d |
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Guo, Jiannan, Loveridge, Edric Joel, Luk, Louis Yu Pan and Allemann, Rudolf Konrad 2013. Effect of dimerization on dihydrofolate reductase catalysis. Biochemistry 52 (22) , pp. 3881-3887. 10.1021/bi4005073 |
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Loveridge, Edric Joel, Matthews, Stella M., Williams, Christopher, Whittaker, Sara B.-M., Günther, Ulrich L., Evans, Rhiannon M., Dawson, William Michael, Crump, Matthew P. and Allemann, Rudolf Konrad 2013. Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate. Biomolecular NMR Assignments 7 (1) , pp. 61-64. 10.1007/s12104-012-9378-x |
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Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2013. 1H, 13C and 15N chemical shift assignments of unliganded Bcl-xL and its complex with a photoresponsive Bak-derived peptide. Biomolecular NMR Assignments 7 (2) , pp. 187-191. 10.1007/s12104-012-9407-9 |
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Li, Jian-Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang-Qing, Wang, Ling-Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao-Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from 'Artemisia annua': Product specificity and catalytic efficiency. Biochemical Journal 451 (3) , pp. 417-426. 10.1042/BJ20130041 |
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Li, Jian‑Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang‑Qing, Wang, Ling‑Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao‑Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochemical Journal -London- 451 (3) , pp. 417-426. 10.1042/BJ20130041 |
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Chen, Mengbin, Al-Lami, Naeemah, Janvier, Marine, D'Antonio, Edward L., Faraldos, Juan A., Cane, David E., Allemann, Rudolf Konrad and Christianson, David W. 2013. Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry 52 (32) , pp. 5441-5453. 10.1021/bi400691v |
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Pickett, John A., Allemann, Rudolf Konrad and Birkett, Michael A. 2013. The semiochemistry of aphids. Natural Product Reports 30 (10) , pp. 1277-1283. 10.1039/c3np70036d |
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van der Kamp, Marc W., Sirirak, Jitnapa, Zurek, Jolanta, Allemann, Rudolf Konrad and Mulholland, Adrian J. 2013. Conformational change and ligand binding in the aristolochene synthase catalytic cycle. Biochemistry 52 (45) , pp. 8094-8105. 10.1021/bi400898k |
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Wysoczanski, Piotr, Mart, Robert J., Loveridge, Edric Joel, Williams, Christopher, Whittaker, Sara B.-M., Crump, Matthew P. and Allemann, Rudolf Konrad 2012. NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL. Journal of the American Chemical Society 134 (18) , pp. 7644-7647. 10.1021/ja302390a |
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Aros Orellana, Danilo Fernando, Gonzalez, Veronica, Allemann, Rudolf Konrad, Müller, Carsten Theodor, Rosati, Carlo and Rogers, Hilary Joan 2012. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers. Journal of Experimental Botany 63 (7) , pp. 2739-2752. 10.1093/jxb/err456 |
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Loveridge, Edric Joel, Behiry, Enas Mamdouh, Guo, Jian Nan and Allemann, Rudolf Konrad 2012. Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis. Nature Chemistry 4 (4) , pp. 292-297. 10.1038/nchem.1296 |
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Miller, David James and Allemann, Rudolf Konrad 2012. Sesquiterpene synthases: Passive catalysts or active players? Natural Product Reports 29 (1) , pp. 60-71. 10.1039/c1np00060h |
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Mart, Robert J., Wysoczanski, Piotr, Kneissl, Sabine, Ricci, Antonio, Brancale, Andrea and Allemann, Rudolf Konrad 2012. Design of photocontrolled RNA-binding peptidomimetics. ChemBioChem 13 (4) , pp. 515-519. 10.1002/cbic.201100800 |
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Faraldos, Juan A., Gonzalez, Veronica and Allemann, Rudolf Konrad 2012. The role of aristolochene synthase in diphosphate activation. Chemical Communications- Royal Society of Chemistry 48 (26) , pp. 3230-3232. 10.1039/c2cc17588f |
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Adams, Sarah Elizabeth, Parr, Christian, Miller, David James, Allemann, Rudolf Konrad and Hallett, Maurice Bartlett 2012. Potent inhibition of Ca2+-dependent activation of calpain-1 by novel mercaptoacrylates. MedChemComm 3 (5) , pp. 566-570. 10.1039/c2md00280a |
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Cascón, Oscar, Touchet, Sabrina, Miller, David James, Gonzalez, Veronica, Faraldos, Juan A. and Allemann, Rudolf Konrad 2012. Chemoenzymatic preparation of germacrene analogues. Chemical Communications 48 (78) , pp. 9702-9704. 10.1039/c2cc35542f |
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Faraldos, Juan A., Gonzalez, Veronica, Li, Amang, Yu, Fanglei, Köksal, Mustafa, Christianson, David W. and Allemann, Rudolf Konrad 2012. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society 134 (51) , pp. 20844-20848. 10.1021/ja311022s |
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Faraldos, Juan A., Miller, David James, Gonzalez, Veronica, Yoosuf-Aly, Fathima Zulfa, Cascón, Oscar, Li, Amang and Allemann, Rudolf Konrad 2012. A 1,6-ring closure mechanism for (+)-δ-cadinene synthase? Journal of the American Chemical Society 134 (13) , pp. 5900-5908. 10.1021/ja211820p |
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Yoosuf-Aly, Zulfa, Faraldos, Juan A., Miller, David James and Allemann, Rudolf Konrad 2012. Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate. Chemical Communications 48 , pp. 7040-7042. 10.1039/c2cc32883f |
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Loveridge, Edric Joel, Tey, Lai-Hock, Behiry, Enas Mamdouh, Dawson, William Michael, Evans, Rhiannon Mari, Whittaker, Sara B.-M., Günther, Ulrich L., Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2011. The role of large-scale motions in catalysis by dihydrofolate reductase. Journal of the American Chemical Society 133 (50) , pp. 20561-20570. 10.1021/ja208844j |
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Faraldos, Juan A., Antonczak, Alicja K., Gonzalez, Veronica, Fullerton, Rebecca, Tippmann, Eric Michael and Allemann, Rudolf Konrad 2011. Probing eudesmane cation−π interactions in catalysis by aristolochene synthase with non-canonical amino acids. Journal of the American Chemical Society 133 (35) , pp. 13906-13909. 10.1021/ja205927u |
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Fricke, Thomas, Mart, Robert J., Watkins, Catherine Louise, Wiltshire, Marie, Errington, Rachel Jane, Smith, Paul James, Jones, Arwyn Tomos and Allemann, Rudolf Konrad 2011. Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. Bioconjugate Chemistry 22 (9) , pp. 1763-1767. 10.1021/bc200338u |
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Loveridge, Edric Joel and Allemann, Rudolf Konrad 2011. Effect of pH on Hydride Transfer by Escherichia coli Dihydrofolate Reductase. ChemBioChem 12 (8) , pp. 1258-1262. 10.1002/cbic.201000794 |
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Faraldos, Juan A., Gonzalez, Veronica, Senske, Michael and Allemann, Rudolf Konrad 2011. Templating effects in aristolochene synthase catalysis: elimination versus cyclisation. Organic & Biomolecular Chemistry 9 (20) , pp. 6920-6923. 10.1039/c1ob06184d |
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Loveridge, Edric Joel, Dawson, William Michael, Evans, Rhiannon Mari, Sobolewska, Anna and Allemann, Rudolf Konrad 2011. Reduced Susceptibility of Moritella profunda Dihydrofolate Reductase to Trimethoprim is Not Due to Glutamate 28. The Protein Journal 30 (8) , pp. 546-548. 10.1007/s10930-011-9361-x |
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Faraldos, Juan A. and Allemann, Rudolf Konrad 2011. Inhibition of (+)-Aristolochene Synthase with Iminium Salts Resembling Eudesmane Cation. Organic Letters 13 (5) , pp. 1202-1205. 10.1021/ol2000843 |
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Fricke, Thomas, Mart, Robert J., Watkins, Catherine Louise, Jones, Arwyn Tomos and Allemann, Rudolf Konrad 2010. Click chemistry for the generation of cell permeable apoptotic peptides. Drug Discovery Today 15 (23-24) , p. 1088. 10.1016/j.drudis.2010.09.375 |
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Tey, Lai-Hock, Loveridge, Edric Joel, Swanwick, Richard, Flitsch, Sabine L. and Allemann, Rudolf Konrad 2010. Highly site-selective stability increases by glycosylation of dihydrofolate reductase. FEBS Journal 277 (9) , pp. 2171-2179. 10.1111/j.1742-4658.2010.07634.x |
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Edwards, Wayne Robert, Williams, Abigail J., Morris, Josephine Lydia, Baldwin, Amy Joy, Allemann, Rudolf Konrad and Jones, Darran Dafydd 2010. Regulation of β-Lactamase activity by remote binding of Heme: functional coupling of unrelated proteins through domain insertion. Biochemistry 49 (31) , pp. 6541-6549. 10.1021/bi100793y |
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Loveridge, Edric Joel, Tey, Lai-Hock and Allemann, Rudolf Konrad 2010. Solvent effects on catalysis by Escherichia coli dihydrofolate reductase. Journal of the American Chemical Society 132 (3) , pp. 1137-1143. 10.1021/ja909353c |
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Evans, Rhiannon Mari, Behiry, Enas Mamdouh, Tey, Lai-Hock, Guo, Jiannan, Loveridge, Edric Joel and Allemann, Rudolf Konrad 2010. Catalysis by Dihydrofolate Reductase from the Psychropiezophile Moritella profunda. ChemBioChem 11 (14) , pp. 2010-2017. 10.1002/cbic.201000341 |
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Faraldos, Juan A., Kariuki, Benson and Allemann, Rudolf Konrad 2010. Intermediacy of Eudesmane Cation during Catalysis by Aristolochene Synthase. Journal of Organic Chemistry 75 (4) , pp. 1119-1125. 10.1021/jo902397v |
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Loveridge, Edric Joel, Behiry, Enas Mamdouh, Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Different reaction mechanisms for mesophilic and thermophilic dihydrofolate reductases. Journal of the American Chemical Society 131 (20) , pp. 6926-6927. 10.1021/ja901441k |
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Allemann, Rudolf Konrad, Evans, Rhiannon Mari and Loveridge, Edric Joel 2009. Probing coupled motions in enzymatic hydrogen tunnelling reactions. Biochemical Society Transactions 37 , pp. 349-353. 10.1042/BST0370349 |
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Loveridge, Edric Joel, Rodriguez, R. J., Swanwick, Richard S. and Allemann, Rudolf Konrad 2009. Effect of Dimerization on the Stability and Catalytic Activity of Dihydrofolate Reductase from the Hyperthermophile Thermotoga maritima. Biochemistry 48 (25) , pp. 5922-5933. 10.1021/bi900411a |
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Loveridge, Edric Joel, Maglia, Giovanni and Allemann, Rudolf Konrad 2009. The Role of Arginine 28 in Catalysis by Dihydrofolate Reductase from the HyperthermophileThermotoga maritima. ChemBioChem 10 (16) , pp. 2624-2627. 10.1002/cbic.200900465 |
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Gennadios, Heather A., Gonzalez, Veronica, Di Costanzo, Luigi, Li, Amang, Yu, Fanglei, Miller, David James, Allemann, Rudolf Konrad and Christianson, David W. 2009. Crystal structure of (+)-δ-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry 48 (26) , pp. 6175-6183. 10.1021/bi900483b |
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Miller, David James, Yu, Fanglei, Knight, David William and Allemann, Rudolf Konrad 2009. 6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase. Organic & Biomolecular Chemistry 7 (5) , pp. 962-975. 10.1039/b817194g |
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Allemann, Rudolf Konrad 2009. Cystine-based Scaffolds for Functional Miniature Proteins. In: Moroder, L. and Buchner, J. eds. Oxidative Folding of Peptides and Proteins, London: RSC Publishing, pp. 381-395. (10.1039/9781847559265-00381) |
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Loveridge, Edric Joel and Allemann, Rudolf Konrad 2009. Direct methods for the analysis of quantum-mechanical tunnelling: dihydrofolate reductase. In: Allemann, Rudolf Konrad and Scrutton, N. S. eds. Quantum Tunnelling in Enzyme-Catalysed Reactions, London: RSC Publishing, pp. 179-198. (10.1039/9781847559975-00179) |
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Allemann, Rudolf Konrad, Young, Neil James, Ma, Shuhua, Truhlar, Donald G. and Gao, Jiali 2009. Synthetic Efficiency in Enzyme Mechanisms Involving Carbocations: Aristolochene Synthase [Addition/Correction]. Journal of the American Chemical Society 131 (27) , p. 9600. 10.1021/ja904281h |
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Hay, Sam, Evans, Rhiannon Mari, Levy, Colin, Loveridge, Edric Joel, Wang, Xi, Leys, David, Allemann, Rudolf Konrad and Scrutton, Nigel S. 2009. Are the Catalytic Properties of Enzymes from Piezophilic Organisms Pressure Adapted? ChemBioChem 10 (14) , pp. 2348-2353. 10.1002/cbic.200900367 |
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Carpenter, Barry K. 2009. The transition-state theory description of enzyme catalysis for classically activated reactions. In: Allemann, Rudolf Konrad and Scrutton, N. S. eds. Quantum tunnelling in enzyme-catalysed reactions, London: RSC Publishing, pp. 1-17. (10.1039/9781847559975-00001) |
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Allemann, Rudolf Konrad and Scrutton, N. S., eds. 2009. Quantum tunnelling in enzyme-catalysed reactions. RSC biomolecular sciences, vol. 18. Cambridge: RSC Publishing. |
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Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2008. FLUO 14-Study of sesquiterpene cyclization reactions using fluorinated farnesyl diphosphate analogs. Abstracts of Papers of the American Chemical Society 236 |
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Shishova, Ekaterina Y., Yu, Fanglei, Miller, David James, Faraldos, Juan A., Zhao, Yuxin X., Coates, Robert M., Allemann, Rudolf Konrad, Cane, David E. and Christianson, David W. 2008. X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. Journal of Biological Chemistry 283 (22) , pp. 15431-15439. 10.1074/jbc.M800659200 |
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Loveridge, Edric Joel, Evans, R. M. and Allemann, Rudolf Konrad 2008. Solvent Effects on Environmentally Coupled Hydrogen Tunnelling During Catalysis by Dihydrofolate Reductase from Thermotoga maritima. Chemistry-a European Journal 14 (34) , pp. 10782-10788. 10.1002/chem.200801804 |
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Allemann, Rudolf Konrad 2008. Chemical wizardry? The generation of diversity in terpenoid biosynthesis. Pure and Applied Chemistry 80 (8) , pp. 1791-1798. 10.1351/pac200880081791 |
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Edwards, W. R., Busse, K., Allemann, Rudolf Konrad and Jones, Darran Dafydd 2008. Linking the functions of unrelated proteins using a novel directed evolution domain insertion method. Nucleic Acids Research 36 (13) 10.1093/nar/gkn363 |
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Fütterer, K., Ravelli, R. B. G., White, S. A., Nicoll, A. J. and Allemann, Rudolf Konrad 2008. Differential specific radiation damage in the CuII-bound and PdII-bound forms of an α-helical foldamer: A case study of crystallographic phasing by RIP and SAD. Acta Crystallographica Section D: Biological Crystallography 64 (3) , pp. 264-272. 10.1107/S0907444907065948 |
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Hay, S., Pang, J. Y., Monaghan, P. J., Wang, X., Evans, R. M., Sutcliffe, M. J., Allemann, Rudolf Konrad and Scrutton, N. S. 2008. Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions. ChemPhysChem 9 (11) , pp. 1536-1539. 10.1002/cphc.200800291 |
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Miller, David James, Gao, Jiali, Truhlar, D. G., Young, Neil James, Gonzalez, Veronica and Allemann, Rudolf Konrad 2008. Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti. Organic & Biomolecular Chemistry 6 (13) , pp. 2346-2354. 10.1039/b804198a |
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Kneissl, Sabine, Loveridge, Edric Joel, Williams, Christopher, Crump, Matthew P. and Allemann, Rudolf Konrad 2008. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL. ChemBioChem 9 (18) , pp. 3046-3054. 10.1002/cbic.200800502 |
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Yu, Fanglei, Miller, David James and Allemann, Rudolf Konrad 2007. Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate. Chemical Communications- Royal Society of Chemistry (40) , pp. 4155-4157. 10.1039/b709562g |
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Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2007. Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A. Chembiochem 8 (15) , pp. 1819-1825. 10.1002/cbic.200700219 |
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Miller, David James, Yu, Fanglei, Young, Neil J and Allemann, Rudolf Konrad 2007. Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity. Organic & Biomolecular Chemistry 5 (20) , pp. 3287-3298. 10.1039/b713301b |
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Miller, D. J. and Allemann, Rudolf Konrad 2007. myo-Inositol Monophosphatase: A Challenging Target for Mood Stabilising Drugs. Mini-Reviews in Chemistry 7 (2) , pp. 107-113. 10.2174/138955707779802624 |
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Pang, Jiayun and Allemann, Rudolf Konrad 2007. Molecular dynamics simulation of thermal unfolding of Thermatoga maritima DHFR. Physical Chemistry Chemical Physics 9 (6) , pp. 711-718. 10.1039/b611210b |
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Allemann, Rudolf Konrad, Young, Neil James, Ma, Shuhua, Truhlar, Donald G. and Gao, Jiali 2007. Synthetic Efficiency in Enzyme Mechanisms Involving Carbocations: Aristolochene Synthase. Journal of the American Chemical Society 129 (43) , pp. 13008-13013. 10.1021/ja0722067 |
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Nicoll, Andrew J., Miller, David James, Fütterer, Klaus, Ravelli, Raymond and Allemann, Rudolf Konrad 2006. Designed high affinity Cu2+ -Binding α-Helical foldamer. Journal of the American Chemical Society 128 (28) , pp. 9187-9193. 10.1021/ja061513u |
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Allemann, Rudolf Konrad, Evans, Rhiannon Mari, Tey, Lai-Hock, Maglia, G., Pang, Jiayun, Rodriguez, Robert, Shrimpton, P. J. and Swanwick, Richard S. 2006. Protein motions during catalysis by dihydrofolate reductases. Philosophical Transactions of the Royal Society of London Series B - Biological Sciences 361 (1472) , pp. 1317-1321. 10.1098/rstb.2006.1865 |
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Maglia, Giovanni, Swanwick, Richard S., Tey, Lai-Hock and Allemann, Rudolf Konrad 2006. Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase. Biochemical Journal 394 (1) , pp. 259-265. 10.1042/BJ20051464 |
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Pang, Jiayun, Pu, Jingzhi, Gao, Jiali, Truhlar, Donald G. and Allemann, Rudolf Konrad 2006. Hydride Transfer Reaction Catalyzed by Hyperthermophilic Dihydrofolate Reductase Is Dominated by Quantum Mechanical Tunneling and Is Promoted by Both Inter- and Intramonomeric Correlated Motions. Journal of the American Chemical Society 128 (24) , pp. 8015-8023. 10.1021/ja061585l |
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Forcat, Silvia and Allemann, Rudolf Konrad 2006. Stabilisation of transition states prior to and following eudesmane cation in aristolochene synthase. Organic & Biomolecular Chemistry 4 (13) , pp. 2563-2567. 10.1039/b604147g |
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Guerrero, Lucia, Smart, Oliver S., Weston, Chris J., Allemann, Rudolf Konrad and Woolley, G. Andrew 2005. Photochemical Regulation of DNA-Binding Specificity of MyoD. Angewandte Chemie International Edition 44 (47) , pp. 7778-7782. 10.1002/anie.200502666 |
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Swanwick, Richard S., Daines, Alison M., Flitsch, Sabine L. and Allemann, Rudolf Konrad 2005. Synthesis of homogenous site-selectively glycosylated proteins. Organic & Biomolecular Chemistry 3 (4) , pp. 572-574. 10.1039/b417133k |
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Swanwick, Richard S., Daines, Alison M., Tey, Lai-Hock, Flitsch, Sabine L. and Allemann, Rudolf Konrad 2005. Increased Thermal Stability of Site-Selectively Glycosylated Dihydrofolate Reductase. ChemBioChem 6 (8) , pp. 1338-1340. 10.1002/cbic.200500103 |
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Guerrero, Lucia, Smart, Oliver S., Woolley, G. Andrew and Allemann, Rudolf Konrad 2005. Photocontrol of DNA Binding Specificity of a Miniature Engrailed Homeodomain. Journal of the American Chemical Society 127 (44) , pp. 15624-15629. 10.1021/ja0550428 |
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Swanwick, Richard S., Shrimpton, Paul J. and Allemann, Rudolf Konrad 2004. Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: the altered structure of a mutant enzyme may form the basis of its diminished datalytic performance. Biochemistry 43 (14) , pp. 4119-4127. 10.1021/bi036164k |
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Miller, David James, Bashir-Uddin Surfraz, M., Akhtar, Mahmoud, Gani, David and Allemann, Rudolf Konrad 2004. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity. Organic & Biomolecular Chemistry 2 (5) , pp. 671-688. 10.1039/b312808c |
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Turner, Elizebeth C., Cureton, Charlotte H., Weston, Chris J., Smart, Oliver S. and Allemann, Rudolf Konrad 2004. Controlling the DNA Binding Specificity of bHLH Proteins through Intramolecular Interactions. Chemistry & Biology 11 (1) , pp. 69-77. 10.1016/j.chembiol.2003.12.015 |
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Nicoll, Andrew J. and Allemann, Rudolf Konrad 2004. Nucleophilic and general acid catalysis at physiological pH by a designed miniature esterase. Organic & Biomolecular Chemistry 2 (15) , pp. 2175-2180. 10.1039/b404730c |
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Bashir-Uddin Surfraz, M., Akhtar, Mahmoud and Allemann, Rudolf Konrad 2004. Bis-benzyl protected 6-amino cyclitols are poisonous to Pd/C catalysed hydrogenolysis of benzyl ethers. Tetrahedron Letters 45 (6) , pp. 1223-1226. 10.1016/j.tetlet.2003.11.130 |
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Weston, Chris J., Cureton, Charly H., Calvert, Melanie J., Smart, Oliver S. and Allemann, Rudolf Konrad 2004. A Stable Miniature Protein with Oxaloacetate Decarboxylase Activity. ChemBioChem 5 (8) , pp. 1075-1080. 10.1002/cbic.200300805 |
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Forcat, Silvia and Allemann, Rudolf Konrad 2004. Dual role for phenylalanine 178 during catalysis by aristolochene synthase. Chemical Communications (18) , pp. 2094-2095. 10.1039/b407932a |
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Nicoll, Andrew J. and Allemann, Rudolf Konrad 2004. Miniature proteomics: designing alpha-helical miniature proteins. Recent Research Developments in Chemistry 2 , pp. 227-243. |
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Allemann, Rudolf Konrad and Maglia, Giovanni 2003. Evidence for Environmentally Coupled Hydrogen Tunneling during Dihydrofolate Reductase Catalysis. Journal of the American Chemical Society 125 (44) , pp. 13372-13373. 10.1021/ja035692g |
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Bashir-Uddin Surfraz, M., Miller, David James., Gani, David and Allemann, Rudolf Konrad 2003. Product-like inhibitors of inositol monophosphatase. Tetrahedron Letters 44 (41) , pp. 7677-7679. 10.1016/S0040-4039(03)01878-1 |
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Maglia, Giovanni, Javed, Masood H. and Allemann, Rudolf Konrad 2003. Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima. Biochemical Journal 374 (2) , pp. 529-535. 10.1042/BJ20030412 |
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Deligeorgopoulou, Athina, Taylor, Susan E., Forcat, Silvia and Allemann, Rudolf Konrad 2003. Stabilisation of eudesmane cation by tryptophan 334 during aristolochene synthase catalysis. Chemical Communications (17) , pp. 2162-2163. 10.1039/b306867f |
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Shrimpton, Paul, Mullaney, Alex and Allemann, Rudolf Konrad 2003. Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductase. Proteins: Structure, Function and Bioinformatics 51 (2) , pp. 216-223. 10.1002/prot.10370 |
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Calvert, Melanie J., Ashton, Peter R. and Allemann, Rudolf Konrad 2002. Germacrene A Is a Product of the Aristolochene Synthase-Mediated Conversion of Farnesylpyrophosphate to Aristolochene. Journal of the American Chemical Society 124 (39) , pp. 11636-11641. 10.1021/ja020762p |
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Kohler, Ursina and Allemann, Rudolf Konrad 2002. Transcription factors. In: Creighton, T. E. ed. Encyclopedia of Molecular Biology, Oxford: Wiley, (10.1002/047120918X.emb1569) |
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Shrimpton, Paul and Allemann, Rudolf Konrad 2002. Role of water in the catalytic cycle of E. coli dihydrofolate reductase. Protein Science 11 (6) , pp. 1442-1451. 10.1110/ps.5060102 |
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Calvert, Melanie J., Taylor, Susan E. and Allemann, Rudolf Konrad 2002. Tyrosine 92 of aristolochene synthase directs cyclisation of farnesyl pyrophosphate. Chemical Communications (20) , pp. 2384-2385. 10.1039/b206517g |
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Taylor, Susan E., Rutherford, Trevor J. and Allemann, Rudolf Konrad 2002. Design of a folded, conformationally stable oxaloacetate decarboxylase. Journal of the Chemical Society, Perkin Transactions 2 2 (4) , pp. 751-755. 10.1039/b200057c |
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Taylor, Susan E., Rutherford, Trevor J. and Allemann, Rudolf Konrad 2001. Design, synthesis and characterisation of a peptide with oxaloacetate decarboxylase activity. Biorganic and Medicinal Chemistry Letters 11 (19) , pp. 2631-2635. 10.1016/S0960-894X(01)00519-4 |
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Dezan, C., Meierhans, D., Künne, A. G. E. and Allemann, Rudolf Konrad 1999. Acquisition of myogenic specificity through replacement of one amino acid of MASH-1 and introduction of an additional α-helical turn. Biological Chemistry 380 (6) , pp. 705-710. 10.1515/BC.1999.088 |
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Allemann, Rudolf Konrad 1999. DNA-protein binding specificity. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 2. New York: Wiley, pp. 743-745. |
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Allemann, Rudolf Konrad 1999. DNA-protein interaction thermodynamics. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 2. New York: Wiley, pp. 745-755. |
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Allemann, Rudolf Konrad 1999. MADS-Box proteins. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 3. New York: Wiley, pp. 1430-1431. |
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Allemann, Rudolf Konrad 1999. Transcription factors. In: Creighton, Thomas E. ed. Encyclopedia of Molecular Biology, Vol. 4. New York: Wiley, pp. 2586-2593. |
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Sieber, M. and Allemann, Rudolf Konrad 1998. Single chain dimers of MASH-1 bind DNA with enhanced affinity. Nucleic Acids Research 26 (6) , pp. 1408-1413. 10.1093/nar/26.6.1408 |
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Künne, Andreas G. E., Sieber, Martin, Meierhans, Daniel and Allemann, Rudolf Konrad 1998. Thermodynamics of the DNA binding reaction of transcription factor MASH-1. Biochemistry 37 (12) , pp. 4217-4223. 10.1021/bi9725374 |
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Meierhans, D. and Allemann, Rudolf Konrad 1998. The N-terminal methionine is a major determinant of the DNA binding specificity of MEF-2C. Journal of Biological Chemistry 273 (40) , pp. 26052-26060. 10.1074/jbc.273.40.26052 |
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Sieber, M. and Allemann, Rudolf Konrad 1998. Arginine (348) is a major determinant of the DNA binding specificity of transcription factor E12. Biological Chemistry 379 (6) , pp. 731-735. |
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Meierhans, D. and Allemann, Rudolf Konrad 1997. High level expression in soluble form, one step purification, and characterization of the DNA binding domain of MEF-2C. Protein Expression and Purification 11 (3) , pp. 297-303. 10.1006/prep.1997.0795 |
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Meierhans, D., Sieber, M. and Allemann, Rudolf Konrad 1997. High affinity binding of MEF-2C correlates with DNA bending. Nucleic Acids Research 25 (22) , pp. 4537-4544. 10.1093/nar/25.22.4537 |
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Künne, Andreas G. E. and Allemann, Rudolf Konrad 1997. Covalently linking BHLH subunits of MASH-1 increases specificity of DNA Binding. Biochemistry 36 (5) , pp. 1085-1091. 10.1021/bi962185l |
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Allemann, Rudolf Konrad and Egli, M. 1997. DNA recognition and bending. Chemistry & Biology 4 (9) , pp. 643-650. 10.1016/S1074-5521(97)90218-0 |
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Künne, A, Meierhans, D. and Allemann, Rudolf Konrad 1996. Basic helix-loop-helix protein MyoD displays modest DNA binding specificity. FEBS Letters 391 (1-2) , pp. 79-83. 10.1016/0014-5793(96)00707-7 |
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Meierhans, Daniel, el-Ariss, Chirine, Neuenschwander, Margrit, Sieber, Martin, Stackhouse, Joseph F. and Allemann, Rudolf Konrad 1995. DNA Binding Specificity of the Basic-Helix-Loop-Helix Protein MASH-1. Biochemistry 34 (35) , pp. 11026-11036. 10.1021/bi00035a008 |
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Johnsson, Kai, Allemann, Rudolf Konrad, Widmer, Hans and Benner, Steven A. 1993. Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides. Nature 365 (6446) , pp. 530-532. 10.1038/365530a0 |
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Whiting, J., Marshall, H., Cook, M., Krumlauf, R., Rigby, P. W., Stott, D. and Allemann, Rudolf Konrad 1991. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes & Development 5 (11) , pp. 2048-2059. 10.1101/gad.5.11.2048 |
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Hunt, P., Whiting, J., Nonchev, S., Sham, M.-H., Marshall, H., Graham, A., Allemann, Rudolf Konrad, Rigby, P., Gulisano, M., Faiella, A., Boncinelli, E. and Krumlauf, R. 1991. The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution. Development 113 (S2) , pp. 63-77. |
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Johnson, K., Allemann, Rudolf Konrad and Benner, S. A. 1990. Designed enzymes. In: Bleasdale, C. and Golding, R. eds. Molecular mechanisms in bioorganic processes, London: Royal Society of Chemistry, pp. 166-187. |
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Benner, Steven A. and Allemann, Rudolf Konrad 1989. The return of pancreatic ribonucleases. Trends in Biochemical Sciences 14 (10) , pp. 396-397. 10.1016/0968-0004(89)90282-X |
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Allemann, Rudolf Konrad, Hung, Rebecca and Benner, Steven A. 1988. Stereochemical profile of the dehydrogenases of Drosophila melanogaster. Journal of the American Chemical Society 110 (16) , pp. 5555-5560. 10.1021/ja00224a046 |
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Benner, S. A. and Allemann, Rudolf Konrad 1987. Natural Selection, Protein Engineering, and the last Riboorganism: Rational Model Building in Biochemistry. Evolution of Catalytic Function, CSH Symposia on Quantitative Biology, vol. 52. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, pp. 53-63. |
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