Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Number of items: 31.

Demiray, Melodi, Miller, David J and Allemann, Rudolf K 2019. Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids. Beilstein Journal of Organic Chemistry 15 , pp. 2184-2190. 10.3762/bjoc.15.215
file

Loizzi, Marianna, Miller, David J. and Allemann, Rudolf K. 2019. Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase. Organic & Biomolecular Chemistry 17 (5) , pp. 1206-1214. 10.1039/C8OB02821D
file

Kalash, Leen, Cresser-Brown, Joel, Habchi, Johnny, Morgan, Connor, Miller, David J., Glen, Robert C., Allemann, Rudolf K. and Bender, Andreas 2018. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space. European Journal of Medicinal Chemistry 157 , pp. 1264-1275. 10.1016/j.ejmech.2018.08.049
file

Huynh, Florence, Grundy, Daniel J., Jenkins, Robert L., Miller, David J. and Allemann, Rudolf K. 2018. Sesquiterpene synthase-catalysed formation of a new medium-sized cyclic terpenoid ether from farnesyl diphosphate analogues. Chembiochem 19 (17) , pp. 1834-1838. 10.1002/cbic.201800218
file

Loizzi, Marianna, Gonzalez Gonzalez, Veronica, Miller, David J. and Allemann, Rudolf K. 2018. Nucleophilic water capture or proton loss: single amino acid switch converts δ-Cadinene synthase into germacradien-4-ol synthase. Chembiochem 19 (1) , pp. 100-105. 10.1002/cbic.201700531
file

Yaldizli, Özgür, Sethi, Varun, Pardini, Matteo, Tur, Carmen, Mok, Kin Y., Muhlert, Nils, Liu, Zheng, Samson, Rebecca S., Wheeler-Kingshott, Claudia A.M., Yousry, Tarek A., Houlden, Henry, Hardy, John, Miller, David H. and Chard, Declan T. 2018. Response to the commentary of Yates RL and DeLuca GC on the study: HLA-DRB1*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis. Multiple Sclerosis and Related Disorders 19 , pp. 168-170. 10.1016/j.msard.2016.08.006

Adams, S.E., Robinson, E.J., Miller, David James, Rizkallah, Pierre, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2015. Conformationally restricted calpain inhibitors. Chemical Science 6 (12) , pp. 6865-6871. 10.1039/c5sc01158b
file

Touchet, Sabrina, Chamberlain, Keith, Woodcock, Christine M., Miller, David James, Birkett, Michael A., Pickett, John and Allemann, Rudolf Konrad 2015. Novel olfactory ligands via terpene synthases. Chemical Communications 51 (35) , pp. 7550-7553. 10.1039/C5CC01814E
file

Adams, Sarah Elizabeth, Rizkallah, Pierre, Miller, David James, Robinson, Emma J., Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2014. The structural basis of differential inhibition of human calpain by indole and phenyl α--mercaptoacrylic acids. Journal of Structural Biology 187 (3) , pp. 236-241. 10.1016/j.jsb.2014.07.004
file

Miller, David James, Adams, Sarah Elizabeth, Hallett, Maurice Bartlett and Allemann, Rudolf Konrad 2013. Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future? Future Medicinal Chemistry 5 (17) , pp. 2057-2074. 10.4155/fmc.13.172

Li, Jian-Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang-Qing, Wang, Ling-Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao-Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from 'Artemisia annua': Product specificity and catalytic efficiency. Biochemical Journal 451 (3) , pp. 417-426. 10.1042/BJ20130041
file

Li, Jian‑Xu, Fang, Xin, Zhao, Qin, Ruan, Ju-Xin, Yang, Chang‑Qing, Wang, Ling‑Jian, Miller, David James, Faraldos, Juan A., Allemann, Rudolf Konrad, Chen, Xiao‑Ya and Zhang, Peng 2013. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochemical Journal -London- 451 (3) , pp. 417-426. 10.1042/BJ20130041

Miller, David James and Allemann, Rudolf Konrad 2012. Sesquiterpene synthases: Passive catalysts or active players? Natural Product Reports 29 (1) , pp. 60-71. 10.1039/c1np00060h

Faraldos, Juan A., Miller, David James, Gonzalez, Veronica, Yoosuf-Aly, Fathima Zulfa, Cascón, Oscar, Li, Amang and Allemann, Rudolf Konrad 2012. A 1,6-ring closure mechanism for (+)-δ-cadinene synthase? Journal of the American Chemical Society 134 (13) , pp. 5900-5908. 10.1021/ja211820p

Adams, Sarah Elizabeth, Parr, Christian, Miller, David James, Allemann, Rudolf Konrad and Hallett, Maurice Bartlett 2012. Potent inhibition of Ca2+-dependent activation of calpain-1 by novel mercaptoacrylates. MedChemComm 3 (5) , pp. 566-570. 10.1039/c2md00280a

Yoosuf-Aly, Zulfa, Faraldos, Juan A., Miller, David James and Allemann, Rudolf Konrad 2012. Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate. Chemical Communications 48 , pp. 7040-7042. 10.1039/c2cc32883f
file

Cascón, Oscar, Touchet, Sabrina, Miller, David James, Gonzalez, Veronica, Faraldos, Juan A. and Allemann, Rudolf Konrad 2012. Chemoenzymatic preparation of germacrene analogues. Chemical Communications 48 (78) , pp. 9702-9704. 10.1039/c2cc35542f
file

Gennadios, Heather A., Gonzalez, Veronica, Di Costanzo, Luigi, Li, Amang, Yu, Fanglei, Miller, David James, Allemann, Rudolf Konrad and Christianson, David W. 2009. Crystal structure of (+)-δ-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry 48 (26) , pp. 6175-6183. 10.1021/bi900483b

Miller, David James, Yu, Fanglei, Knight, David William and Allemann, Rudolf Konrad 2009. 6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase. Organic & Biomolecular Chemistry 7 (5) , pp. 962-975. 10.1039/b817194g

Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2008. FLUO 14-Study of sesquiterpene cyclization reactions using fluorinated farnesyl diphosphate analogs. Abstracts of Papers of the American Chemical Society 236

Shishova, Ekaterina Y., Yu, Fanglei, Miller, David James, Faraldos, Juan A., Zhao, Yuxin X., Coates, Robert M., Allemann, Rudolf Konrad, Cane, David E. and Christianson, David W. 2008. X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis. Journal of Biological Chemistry 283 (22) , pp. 15431-15439. 10.1074/jbc.M800659200

Miller, David James, Gao, Jiali, Truhlar, D. G., Young, Neil James, Gonzalez, Veronica and Allemann, Rudolf Konrad 2008. Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti. Organic & Biomolecular Chemistry 6 (13) , pp. 2346-2354. 10.1039/b804198a

Yu, Fanglei, Miller, David James and Allemann, Rudolf Konrad 2007. Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate. Chemical Communications- Royal Society of Chemistry (40) , pp. 4155-4157. 10.1039/b709562g

Miller, David James, Yu, Fanglei and Allemann, Rudolf Konrad 2007. Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A. Chembiochem 8 (15) , pp. 1819-1825. 10.1002/cbic.200700219

Miller, David James, Yu, Fanglei, Young, Neil J and Allemann, Rudolf Konrad 2007. Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity. Organic & Biomolecular Chemistry 5 (20) , pp. 3287-3298. 10.1039/b713301b

Nicoll, Andrew J., Miller, David James, Fütterer, Klaus, Ravelli, Raymond and Allemann, Rudolf Konrad 2006. Designed high affinity Cu2+ -Binding α-Helical foldamer. Journal of the American Chemical Society 128 (28) , pp. 9187-9193. 10.1021/ja061513u

Miller, David James, Bashir-Uddin Surfraz, M., Akhtar, Mahmoud, Gani, David and Allemann, Rudolf Konrad 2004. Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity. Organic & Biomolecular Chemistry 2 (5) , pp. 671-688. 10.1039/b312808c

Bashir-Uddin Surfraz, M., Miller, David James., Gani, David and Allemann, Rudolf Konrad 2003. Product-like inhibitors of inositol monophosphatase. Tetrahedron Letters 44 (41) , pp. 7677-7679. 10.1016/S0040-4039(03)01878-1

Andersen, Jo-Ann M., Karodia, Nazira, Miller, David James, Stones, Duane and Gani, David 1998. Preparation and catalytic properties of resin bound binuclear rhodium tetracarboxylate complexes. Tetrahedron Letters 39 (42) , pp. 7815-7818. 10.1016/S0040-4039(98)01709-2

Stones, Duane, Miller, David James, Beaton, Martin W., Rutherford, Trevor J. and Gani, David 1998. A method for the quantification of resin loading using 19F gel phase NMR spectroscopy and a new method for benzyl ether linker cleavage in solid phase chemistry. Tetrahedron Letters 39 (27) , pp. 4875-4878. 10.1016/S0040-4039(98)00883-1

Miller, David James, Hammond, Stephen M., Anderluzzi, Daniela and Bugg, Timothy D. H. 1998. Aminoalkylphosphinate inhibitors of D-Ala-D-Ala adding enzyme. Journal of the Chemical Society, Perkin Transactions 1 (1) , pp. 131-132. 10.1039/a704097k

This list was generated on Tue Dec 10 05:05:02 2019 GMT.