Browse by Current Cardiff authors

Wheeler, Philip Anthony, Chu, Michael K., Holmes, Rosemary A., Woodley, Owain W., Jones, Ceri S., Maggs, Rhydian, Staffurth, John, Palaniappan, Nachi, Spezi, Emiliano, Lewis, David G., Campbell, Sue, Fitzgibbon, Jim and Millin, Anthony E 2019. Evaluating the application of Pareto navigation guided automated radiotherapy treatment planning to prostate cancer. Radiotherapy and Oncology 10.1016/j.radonc.2019.08.001 Item availability restricted.

Hargreaves, S., Johnstone, E., Parkinson, Craig, Rackley, T., Spezi, Emiliano, Staffurth, John and Evans, M. 2019. Interim 18F-FDG positron emission tomography/computed tomography during chemoradiotherapy in the management of cancer patients: a response [Letter]. Clinical Oncology 31 (9) , pp. 669-670. 10.1016/j.clon.2019.05.005 Item availability restricted.

Payne, Heather, McMenemin, Rhona, Bahl, Amit, Greene, Damian and Staffurth, John 2019. Measuring testosterone and testosterone replacement therapy in men receiving androgen deprivation therapy for prostate cancer: A survey of UK uro-oncologists' opinions and practice. International Journal of Clinical Practice 73 (9) , pp. 1-6. 10.1111/ijcp.13292 Item availability restricted.

Cox, Samantha, Cleves, Anne, Clementel, Enrico, Miles, Elizabeth, Staffurth, John and Gwynne, Sarah 2019. Impact of deviations in target volume delineation - Time for a new RTQA approach? Radiotherapy and Oncology 137 , pp. 1-8. 10.1016/j.radonc.2019.04.012 Item availability restricted.

Richards, R., Kinnersley, Paul, Brain, Katherine, Staffurth, John and Wood, Fiona 2019. The preferences of patients with cancer regarding an app to help them to meet their illness-related information needs: a qualitative interview study. JMIR mHealth and uHealth 7 (7) , e14187. 10.2196/14187

Whybra, Philip, Parkinson, Craig, Foley, Kieran, Staffurth, John and Spezi, Emiliano 2019. Assessing radiomic feature robustness to interpolation in 18F-FDG PET imaging. Scientific Reports 9 (1) , 9649. 10.1038/s41598-019-46030-0

Nelson, Annmarie, Mann, Mala and Staffurth, John 2019. Methods of assessing late radiotherapy effects on bowel function. Current Opinion in Supportive and Palliative Care 13 (2) , pp. 134-141. 10.1097/SPC.0000000000000422 Item availability restricted.

Wheeler, Philip A., Chu, Michael, Holmes, Rosemary, Smyth, Maeve, Maggs, Rhydian, Spezi, Emiliano, Staffurth, John, Lewis, David G. and Millin, Anthony E. 2019. Utilisation of Pareto navigation techniques to calibrate a fully automated radiotherapy treatment planning solution. Physics and Imaging in Radiation Oncology 10 , pp. 41-48. 10.1016/j.phro.2019.04.005 Item availability restricted.

Parkinson, Craig, Evans, Mererid, Guerrero-Urbano, Teresa, Michaelidou, Andriana, Pike, Lucy, Barrington, Sally, Jayaprakasam, Vetri, Rackley, Thomas, Palaniappan, Nachi, Staffurth, John, Marshall, Christopher and Spezi, Emiliano 2019. Machine-learned target volume delineation of 18F-FDG PET images after one cycle of induction chemotherapy. Physica Medica, European Journal of Medical Physics 61 , pp. 85-93. 10.1016/j.ejmp.2019.04.020 Item availability restricted.

Jadon, Rashmi, Higgins, Emma, Hanna, Louise, Evans, Mererid, Coles, Bernadette and Staffurth, John 2019. A systematic review of dose-volume predictors and constraints for late bowel toxicity following pelvic radiotherapy. Radiation Oncology 14 (1) , -. 10.1186/s13014-019-1262-8

Wheeler, P., West, N., Powis, R., Maggs, R., Chu, M., Pearson, R.A., Willis, N., Kurec, B., Youings, M., Lewis, D.G., Staffurth, John, Spezi, Emiliano and Millin, A.E. 2019. OC-0183 Multi-institutional evaluation of a Pareto navigation guided automated planning solution. Radiotherapy and Oncology 133 (S1) , S92. 10.1016/S0167-8140(19)30603-6

Whybra, P., Parkinson, C., Foley, K., Staffurth, J. and Spezi, E. 2019. A novel normalisation technique for voxel size dependent radiomic features in oesophageal cancer [Abstract]. Radiotherapy and Oncology 133 , S523-S524. 10.1016/S0167-8140(19)31383-0

Piazzese, C., Whybra, P., Carrington, R., Crosby, T., Staffurth, J., Foley, K. and Spezi, E. 2019. Stability and prognostic significance of CT radiomic features from oesophageal cancer patients [Abstract]. Radiotherapy and Oncology 133 , S524-S525. 10.1016/S0167-8140(19)31384-2

Whybra, P., Parkinson, C., Foley, K., Staffurth, J. and Spezi, E. 2019. PO-0963 A novel normalisation technique for voxel size dependent radiomic features in oesophageal cancer. Radiotherapy and Oncology 133 (S1) , S523-S524. 10.1016/S0167-8140(19)31383-0

Evans, E., Piazzese, C., Spezi, E., Staffurth, J. and Gwynne, S. 2019. EP-1666 ARENA: Improving training in target volume delineation for radiotherapy. Radiotherapy and Oncology 133 (S1) , S896-S897. 10.1016/S0167-8140(19)32086-9

Piazzese, Concetta, Whybra, Philip, Carrington, R., Crosby, T., Staffurth, John, Foley, Kieran and Spezi, Emiliano 2019. PO-0964 Stability and prognostic significance of CT radiomic features from oesophageal cancer patients. Radiotherapy and Oncology 133 (S1) , S524-S525. 10.1016/S0167-8140(19)31384-2

Foley, Kieran, Whybra, Philip, Kalendralis, P, Larue, R, Berbee, M, Sosef, M, Parkinson, Craig, Staffurth, John, Crosby, Thomas, Roberts, S, Dekker, A, Wee, L and Spezi, Emiliano 2019. External validation of a prognostic model incorporating quantitative PET image features in esophageal cancer. Radiotherapy and Oncology 133 , pp. 205-212. 10.1016/j.radonc.2018.10.033 Item availability restricted.

Dearnaley, David, Griffin, Clare L., Lewis, Rebecca, Mayles, Philip, Mayles, Helen, Naismith, Olivia F., Harris, Victoria, Scrase, Christopher D., Staffurth, John, Syndikus, Isabel, Zarkar, Anjali, Ford, Daniel R., Rimmer, Yvonne L., Horan, Gail, Khoo, Vincent, Frew, John, Venkitaraman, Ramachandran and Hall, Emma 2019. Toxicity and patient-reported outcomes of a phase 2 randomized trial of prostate and pelvic lymph node versus prostate only radiotherapy in advanced localised prostate cancer (PIVOTAL). International Journal of Radiation Oncology - Biology - Physics 103 (3) , pp. 605-617. 10.1016/j.ijrobp.2018.10.003

Parkinson, Craig, Foley, Kieran, Whybra, Philip, Hills, Robert K., Roberts, Ashley, Marshall, Christopher, Staffurth, John and Spezi, Emiliano 2018. Dependency of patient risk stratification on PET target volume definition in oesophageal cancer. Presented at: ESTRO, Barcelona, Spain, 20-24 April 2018.

Richards, Becky, Kinnersley, Paul, Brain, Katherine, McCutchan, Grace, Staffurth, John and Wood, Fiona 2018. The use of mobile devices to help patients with cancer to meet their illness-related information needs in non-inpatient settings: a systematic review. JMIR mHealth and uHealth 6 (2) , e10026. 10.2196/10026

Woods, Beth S., Sideris, Eleftherios, Sydes, Matthew R., Gannon, Melissa R., Parmar, Mahesh K.B., Alzouebi, Mymoona, Attard, Gerhardt, Birtle, Alison J., Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir R., Cook, Audrey, Cross, William R., Dearnaley, David P., Gale, Joanna, Gibbs, Stephanie, Graham, John D., Hughes, Robert, Jones, Rob J., Laing, Robert, Mason, Malcolm D., Matheson, David, McLaren, Duncan B., Millman, Robin, O'Sullivan, Joe M., Parikh, Omi, Parker, Christopher C., Peedell, Clive, Protheroe, Andrew, Ritchie, Alastair W.S., Robinson, Angus, Russell, J. Martin, Simms, Matthew S., Srihari, Narayanan N., Srinivasan, Rajaguru, Staffurth, John N., Sundar, Santhanam, Thalmann, George N., Tolan, Shaun, Tran, Anna T.H., Tsang, David, Wagstaff, John, James, Nicholas D. and Sculpher, Mark J. 2018. Addition of Docetaxel to first-line long-term hormone therapy in prostate cancer (STAMPEDE): Modelling to estimate long-term survival, quality-adjusted survival, and cost-effectiveness. European Urology Oncology 1 (6) , pp. 449-458. 10.1016/j.euo.2018.06.004

Parkinson, Craig, Whybra, Phil, Staffurth, John, Marshall, Chris and Spezi, Emiliano 2018. ATLAAS - Investigation into the incorporation of morphological data on automated segmentation. Presented at: EANM Congress 2018: European Association of Nuclear Medicine., Dusseldorf, Germany, 12-18 October 2018.

Parkinson, Craig, Pike, Lucy, Barrington, Sally, Guerrero-Urbano, Teresa, Evans, Mererid, Staffurth, John, Marshall, Chris and Spezi, Emiliano 2018. Target volume delineation of FDG PET images post one cycle of induction chemotherapy in oropharyngeal cancer using advanced automated segmentation methods. Presented at: ESTRO 37, Barcelona, 20-24 April 2018.

Parkinson, Craig, Foley, Kieran, Whybra, Philip, Hills, Robert, Roberts, Ashley, Marshall, Christopher, Staffurth, John N. and Spezi, Emiliano 2018. Evaluation of prognostic models developed using standardised image features from different PET automated segmentation methods. EJNMMI Research 8 , 29. 10.1186/s13550-018-0379-3

Piazzese, C., Whybra, P., Carrington, R., Crosby, T., Staffurth, J., Foley, K. and Spezi, E. 2018. Evaluation of 2D and 3D radiomics features extracted from CT images of oesophageal cancer patients. Radiotherapy and Oncology 127 , S1180-S1181. 10.1016/S0167-8140(18)32450-2

Donovan, Jenny L., Young, Grace J., Walsh, Eleanor I., Metcalfe, Chris, Lane, J. Athene, Martin, Richard M., Tazewell, Marta K., Davis, Michael, Peters, Tim J., Turner, Emma L., Mills, Nicola, Khazragui, Hanan, Khera, Tarnjit K., Neal, David E., Hamdy, Freddie C., Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Holding, Peter, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard, Mason, Malcolm, Oxley, Jon, Paul, Alan, Paez, Edgar, Rosario, Derek J., Rowe, Edward and Staffurth, John 2018. A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial. Journal of Clinical Epidemiology 96 , pp. 35-46. 10.1016/j.jclinepi.2017.12.019

Whybra, Philip, Foley, Kieran, Parkinson, Craig, Staffurth, John and Spezi, Emiliano 2018. Effect of interpolation on 3D texture analysis of PET imaging in oesophageal cancer. Radiotherapy and Oncology 127 (S1) , S1164-S1165. 10.1016/S0167-8140(18)32426-5

Parkinson, C., Foley, K., Whybra, P., Hills, R., Roberts, A., Marshall, C., Staffurth, J. and Spezi, E. 2018. Dependency of patient risk stratification on PET target volume definition in Oesophageal cancer. Radiotherapy and Oncology 127 (S1) , S503-S504. 10.1016/S0167-8140(18)31241-6

Parkinson, C., Pike, L., Barrington, S., Guerrero-Urbano, T., Evans, M., Marshall, C., Staffurth, J. and Spezi, E. 2018. Target volume delineation of PET post one cycle of induction chemotherapy in oropharyngeal cancer. Radiotherapy and Oncology 127 (S1) , S634-S635. 10.1016/S0167-8140(18)31436-1

Murray, J, Gulliford, S, Griffin, C, Staffurth, John, Panades, M, Scrase, C, Parker, C, Khoo, V, Dean, J, Mayles, H, Mayles, P, Thomas, S, Naismith, O, Mossop, H, Hall, E and Dearnaley, D 2018. Erectile potency and radiation dose to the penile bulb dose constraints derived from the CHHiP randomised prostate radiotherapy trial. European Urology Item availability restricted.

Wills, Lucy, Maggs, Rhydian, Lewis, Geraint, Jones, Gareth, Nixon, Lisette Sheena, Staffurth, John Nicholas and Crosby, Thomas 2017. Quality assurance of the SCOPE 1 trial in oesophageal radiotherapy. Radiation Oncology 12 (1) , 179. 10.1186/s13014-017-0916-7

Hurt, Chris Nicholas, Falk, S., Crosby, T., McDonald, A., Ray, R., Joseph, G., Staffurth, John Nicholas, Abrams, R. A., Griffiths, G., Maughan, T. and Mukherjee, S. 2017. Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of gemcitabine- or capecitabine-based chemoradiation for locally advanced pancreatic cancer. British Journal of Cancer 116 (10) , pp. 1264-1270. 10.1038/bjc.2017.95

Crosby, Tom, Hurt, Christopher, Falk, S, Gollins, S, Staffurth, John, Ray, Ruby, Bridgewater, J A, Geh, J I, Cunningham, D, Blazeby, J, Roy, R, Maughan, Timothy, Griffiths, Gwyn and Mukherjee, Saptarshi 2017. Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/? cetuximab in oesophageal cancer. British Journal of Cancer 116 (6) , pp. 709-716. 10.1038/bjc.2017.21

Gnanapragasam, VJ, Hori, S, Johnston, T, Smith, D, Muir, K, Alonzi, R, Winkler, M, Warren, A, Staffurth, John, Khoo, V, Tree, A, Macneill, A, McMenemin, R, Mason, Malcolm, Cathcart, P, de Souza, N, Sooriakumaran, P, Weston, R, Wylie, J, Hall, E, Lane, A, Cross, W, Syndikus, I and Koupparis, A 2016. Clinical management and research priorities for high-risk prostate cancer in the UK: Meeting report of a multidisciplinary panel in conjunction with the NCRI Prostate Cancer Clinical Studies Localised Subgroup. Journal of Clinical Urology 9 (6) , pp. 369-379. 10.1177/2051415816651362

Johnston, Thomas J., Shaw, Greg L., Lamb, Alastair D., Parashar, Deepak, Greenberg, David, Xiong, Tengbin, Edwards, Alison L., Gnanapragasam, Vincent, Holding, Peter, Herbert, Phillipa, Davis, Michael, Mizielinsk, Elizabeth, Lane, J. Athene, Oxley, Jon, Robinson, Mary, Mason, Malcolm, Staffurth, John, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard, Prescott, Steve, Paul, Alan, Powell, Philip, Rosario, Derek, Rowe, Edward, Donovan, Jenny L., Hamdy, Freddie C. and Neal, David E. 2016. Mortality among men with advanced prostate cancer excluded from the ProtecT trial. European Urology 71 (3) , pp. 381-388. 10.1016/j.eururo.2016.09.040

Taylor, Sophia, Byrne, Anthony, Adams, R., Turner, J., Hanna, L., Staffurth, John Nicholas, Farnell, Damian, Sivell, Stephanie, Nelson, Annmarie and Green, J. 2016. The three-item ALERT-B questionnaire provides a validated screening tool to detect chronic gastrointestinal symptoms after pelvic radiotherapy in cancer survivors. Clinical Oncology 28 (10) , e139-e147. 10.1016/j.clon.2016.06.004

Taylor, Sophia, Weyinmi, Demeyin, Muls, Ann, Ferguson, Catherine, Farnell, Damian J. J., Cohen, David, Andreyev, Jervoise, Green, John, Smith, Lesley, Ahmedzai, Sam, Pickett, Sara, Nelson, Annmarie and Staffurth, John Nicholas 2016. Improving the well-being of men by Evaluating and Addressing the Gastrointestinal Late Effects (EAGLE) of radical treatment for prostate cancer: study protocol for a mixed-method implementation project. British Medical Journal Open 6 (10) , e011773. 10.1136/bmjopen-2016-011773

Tanguay, J. S., Catlow, Charles Richard A., Smith, C., Barber, J., Staffurth, John Nicholas, Kumar, S., Palaniappan, N., Button, M. and Mason, Malcolm David 2016. High risk of neutropenia for hormone-naive prostate cancer patients receiving STAMPEDE-style upfront Docetaxel chemotherapy in usual clinical practice. Clinical Oncology 28 (9) , p. 611. 10.1016/j.clon.2016.03.006

Fokas, Emmanouil, Spezi, Emiliano, Patel, Neel, Hurt, Chris Nicholas, Nixon, Lisette Sheena, Chu, Kwun-Ye, Staffurth, John Nicholas, Abrams, Ross and Mukherjee, Somnath 2016. Comparison of investigator-delineated gross tumour volumes and quality assurance in pancreatic cancer: analysis of the on-trial cases for the SCALOP trial. Radiotherapy and Oncology 120 (2) , pp. 212-216. 10.1016/j.radonc.2016.07.002

Dearnaley, David, Syndikus, Isabel, Mossop, Helen, Khoo, Vincent, Birtle, Alison, Bloomfield, David, Graham, John, Kirkbride, Peter, Logue, John, Malik, Zafar, Money-Kyrle, Julian, O'Sullivan, Joe M, Panades, Miguel, Parker, Chris, Patterson, Helen, Scrase, Christopher, Staffurth, John, Stockdale, Andrew, Tremlett, Jean, Bidmead, Margaret, Mayles, Helen, Naismith, Olivia, South, Chris, Gao, Annie, Cruickshank, Clare, Hassan, Shama, Pugh, Julia, Griffin, Clare and Hall, Emma 2016. Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial. Lancet Oncology 17 (8) , pp. 1047-1060. 10.1016/S1470-2045(16)30102-4

Andronis, Lazaros, Goranitis, Ilias, Pirrie, Sarah, Pope, Ann, Barton, Darren, Collins, Stuart, Daunton, Adam, McLaren, Duncan, O'Sullivan, Joe M., Parker, Chris, Porfiri, Emilio, Staffurth, John, Stanley, Andrew, Wylie, James, Beesley, Sharon, Birtle, Alison, Brown, Janet E., Chakraborti, Prabir, Hussain, Syed A., Russell, J. Martin, Billingham, Lucinda J. and James, Nicholas D. 2016. Cost-effectiveness of zoledronic acid and strontium-89 as bone protecting treatments in addition to chemotherapy in patients with metastatic castrate-refractory prostate cancer: results from the TRAPEZE trial (ISRCTN 12808747). BJU International 119 (4) , pp. 522-529. 10.1111/bju.13549

James, Nicholas, Pirrie, Sarah, Pope, Ann, Barton, Darren, Andronis, Lazaros, Goranitis, Ilias, Collins, Stuart, McLaren, Duncan, O'Sullivan, Joe, Parker, Chris, Porfiri, Emilio, Staffurth, John, Stanley, Andrew, Wylie, James, Beesley, Sharon, Birtle, Alison, Brown, Janet, Chakraborti, Prabir, Russell, Martin and Billingham, Lucinda 2016. TRAPEZE: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of chemotherapy with zoledronic acid, strontium-89, or both, in men with bony metastatic castration-refractory prostate cancer. Health Technology Assessment 20 (53) 10.3310/hta20530

Fokas, E., Spezi, Emiliano, Patel, N., Hurt, Chris Nicholas, Nixon, Lisette Sheena, Chu, K., Joseph, G., Staffurth, John Nicholas, Abrams, R. and Mukherjee, S. 2016. P-222 Analysis of tumour contours and radiotherapy planning of "on-trial" patients undergoing chemoradiotherapy (CRT) in SCALOP trial: does pre-trial Radiotherapy Quality Assurance (RTQA) improve the quality of "on-trial" radiotherapy? Annals of Oncology 27 (suppl) , ii64.3-ii65.. 10.1093/annonc/mdw199.214

Sharma, Ricky A., Plummer, Ruth, Stock, Julie K., Greenhalgh, Tessa A., Ataman, Ozlem, Kelly, Stephen, Clay, Robert, Adams, Richard Alexander, Baird, Richard D., Billingham, Lucinda, Brown, Sarah R., Buckland, Sean, Bulbeck, Helen, Chalmers, Anthony J., Clack, Glen, Cranston, Aaron N., Damstrup, Lars, Ferraldeschi, Roberta, Forster, Martin D., Golec, Julian, Hagan, Russell M., Hall, Emma, Hanauske, Axel-R., Harrington, Kevin J., Haswell, Tom, Hawkins, Maria A., Illidge, Tim, Jones, Hazel, Kennedy, Andrew S., McDonald, Fiona, Melcher, Thorsten, O'Connor, James P. B., Pollard, John R., Saunders, Mark P., Sebag-Montefiore, David, Smitt, Melanie, Staffurth, John, Stratford, Ian J. and Wedge, Stephen R. 2016. Clinical development of new drug-radiotherapy combinations. Nature Reviews Clinical Oncology 13 , pp. 627-642. 10.1038/nrclinonc.2016.79

James, Nicholas D., Pirrie, Sarah J., Pope, Ann M., Barton, Darren, Andronis, Lazaros, Goranitis, Ilias, Collins, Stuart, Daunton, Adam, McLaren, Duncan, O'Sullivan, Joe, Parker, Christopher, Porfiri, Emilio, Staffurth, John, Stanley, Andrew, Wylie, James, Beesley, Sharon, Birtle, Alison, Brown, Janet, Chakraborti, Prabir, Hussain, Syed, Russell, Martin and Billingham, Lucinda J. 2016. Clinical outcomes and survival following treatment of metastatic castrate-refractory prostate cancer with docetaxel alone or with strontium-89, zoledronic acid, or both. JAMA Oncology 2 (4) , pp. 493-499. 10.1001/jamaoncol.2015.5570

Carrington, R., Spezi, Emiliano, Gwynne, S., Dutton, P., Hurt, Chris Nicholas, Staffurth, John Nicholas and Crosby, T. 2016. The influence of radiotherapy treatment method on dose distribution and its relation to patient outcome in the SCOPE 1 oesophageal cancer trial using Type B algorithms. BMC Medical Physics 42 (6) , p. 3703. 10.1186/s13014-016-0594-x

Carrington, Rhys, Spezi, Emiliano, Gwynne, Sarah, Dutton, Peter, Hurt, Chris Nicholas, Staffurth, John Nicholas and Crosby, Thomas 2016. The influence of dose distribution on treatment outcome in the SCOPE 1 oesophageal cancer trial. Radiation Oncology 11 (19) , pp. 1-8. 10.1186/s13014-016-0594-x

Abraham, Jacinta and Staffurth, John Nicholas 2016. Hormonal therapy for cancer. Medicine 44 (1) , pp. 30-33. 10.1016/j.mpmed.2015.10.014

Taylor, Sophia Emily, Muls, Ann, Andreyev, Jervoise, Green, John, Farnell, Damian, Smith, Lesely, Ahmedzai, Sam H., Pickett, Sara, Ferguson, Catherine, Fitzsimmons, Deborah, Cambell, Susan, O'Shea, Raymond, Nelson, Annmarie and Staffurth, John Nicholas 2016. Late effects of pelvic radiation treatment (EAGLE study) [Abstract]. Journal of Clinical Oncology 34 (3) , p. 159. 10.1200/jco.2016.34.3_suppl.159

Gwynne, Sarah, Jones, Gareth, Maggs, Rhydian, Eaton, David, Miles, Elizabeth, Staffurth, John, Nixon, Lisette, Ray, Ruby, Lewis, Geraint, Crosby, Thomas and Spezi, Emiliano 2016. Prospective review of radiotherapy trials through implementation of standardised multi-centre workflow and IT infrastructure. British Journal of Radiology 89 (1064) , 20160020. 10.1259/bjr.20160020

Fokas, Emmanouil, Clifford, Charlotte, Spezi, Emiliano, Joseph, George, Branagan, Jennifer, Hurt, Chris Nicholas, Nixon, Lisette Sheena, Abrams, Ross, Staffurth, John Nicholas and Mukherjee, Somnath 2015. Comparison of investigator-delineated gross tumor volumes and quality assurance in pancreatic cancer: Analysis of the pretrial benchmark case for the SCALOP trial. Radiotherapy and Oncology 117 (3) , pp. 432-437. 10.1016/j.radonc.2015.08.026

Carrington, Rhys, Staffurth, John Nicholas, Warren, Samantha, Partridge, Mike, Hurt, Chris Nicholas, Spezi, Emiliano, Gwynne, Sarah, Hawkins, Maria A. and Crosby, Thomas 2015. The effect of dose escalation on gastric toxicity when treating lower oesophageal tumours: a radiobiological investigation. Radiation Oncology 10 , 236. 10.1186/s13014-015-0537-y

Hurt, Chris Nicholas, Mukherjee, Somnath, Bridgewater, John, Falk, Stephen, Crosby, Tom, McDonald, Alec, Joseph, George, Staffurth, John Nicholas, Abrams, Ross A., Blazeby, Jane M., Bridges, Sarah, Dutton, Peter, Griffiths, Gareth, Maughan, Timothy and Johnson, Colin 2015. Health-related quality of life in SCALOP, a randomized Phase 2 trial comparing chemoradiation therapy regimens in locally advanced pancreatic cancer. International Journal of Radiation Oncology Biology Physics 93 (4) , pp. 810-818.

Hurt, Chris Nicholas, Mukherjee, Somnath, Bridgewater, John, Falk, Stephen, Crosby, Tom, McDonald, Alec, Joseph, George, Staffurth, John Nicholas, Abrams, Ross A., Blazeby, Jane M., Bridges, Sarah, Dutton, Peter, Griffiths, Gareth, Maughan, Tim and Johnson, Colin 2015. Health related quality of life in SCALOP, a randomized phase II trial comparing chemoradiotherapy regimens in locally advanced pancreatic cancer (LAPC). International Journal of Radiation Oncology*Biology*Physics 93 (4) , pp. 810-818. 10.1016/j.ijrobp.2015.08.026

Rees, J., Hurt, Chris Nicholas, Gollins, S., Mukherjee, S., Maughan, Timothy, Falk, S. J., Staffurth, John Nicholas, Ray, Ruby, Bashir Mohamad, Nurul, Geh, J. I., Cunningham, D., Roy, R., Bridgewater, J., Griffiths, G., Nixon, Lisette Sheena, Blazeby, J. M. and Crosby, T. 2015. Patient-reported outcomes during and after definitive chemoradiotherapy for oesophageal cancer. British Journal of Cancer 113 (4) , pp. 603-610. 10.1038/bjc.2015.258

Harris, Victoria A., Staffurth, John Nicholas, Naismith, Olivia, Esmail, Alikhan, Gulliford, Sarah, Khoo, Vincent, Lewis, Rebecca, Littler, John, McNair, Helen, Sadoyze, Azmat, Scrase, Christopher, Sohaib, Aslam, Syndikus, Isabel, Zarkar, Anjali, Hall, Emma and Dearnaley, David 2015. Consensus guidelines and contouring atlas for pelvic node delineation in prostate and pelvic node intensity modulated radiation therapy. International Journal of Radiation Oncology*Biology*Physics 92 (4) , pp. 874-883. 10.1016/j.ijrobp.2015.03.021

Carrington, R., Staffurth, John Nicholas, Warren, S., Partridge, M., Spezi, Emiliano, Gwynne, S., Hawkins, M. and Crosby, T. 2015. A radiobiological investigation of dose escalation in lower oesophageal tumours with a focus on gastric toxicity. Medical Physics 42 (6) , pp. 3346-3347. 10.1118/1.4924430

Salimu, Josephine, Spary, Lisa Kate, Al-Taei, Saly, Clayton, Aled, Mason, Malcolm David, Staffurth, John and Tabi, Zsuzsanna 2015. Cross-Presentation of the Oncofetal Tumor Antigen 5T4 from Irradiated Prostate Cancer Cells—A Key Role for Heat-Shock Protein 70 and Receptor CD91. Cancer Immunology Research 3 (6) , pp. 678-688. 10.1158/2326-6066.CIR-14-0079

Adamson, Douglas, Blazeby, Jane, Nelson, Annmarie, Hurt, Chris Nicholas, Nixon, Lisette Sheena, Fitzgibbon, Jim, Crosby, Tom, Staffurth, John Nicholas, Evans, Mim, Kelly, Noreen, Cohen, David, Griffiths, Gareth and Byrne, Anthony 2014. Palliative radiotherapy in addition to self-expanding metal stent for improving dysphagia and survival in advanced oesophageal cancer (ROCS: Radiotherapy after Oesophageal Cancer Stenting): study protocol for a randomized controlled trial. Trials 15 , 402. 10.1186/1745-6215-15-402

Spary, Lisa Kate, Al-Taei, Saly, Salimu, Josephine, Cook, Alexander, Ager, Ann, Watson, Heulwen Angharad, Clayton, Aled, Staffurth, John Nicholas, Mason, Malcolm David and Tabi, Zsuzsanna 2014. Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation. The Journal of Immunology 192 (7) , pp. 3101-3110. 10.4049/jimmunol.1302736

Jadon, R., Pembroke, C.A., Hanna, C.L., Palaniappan, N., Evans, M., Cleves, A.E. and Staffurth, John 2014. A systematic review of organ motion and image-guided strategies in external beam radiotherapy for cervical cancer. Clinical Oncology 26 (4) , pp. 185-196. 10.1016/j.clon.2013.11.031

Voskoboynik, Mark, Staffurth, John Nicholas, Malik, Zafar, Sweeney, Christopher and Chowdhury, Simon 2014. 'Charting a new course for prostate cancer' - currying favor for docetaxel in hormone-sensitive metastatic prostate cancer. Expert Review of Anticancer Therapy 14 (11) , pp. 1253-1256. 10.1586/14737140.2014.971112

Nixon, Lisette Sheena, Mukherjee, S., Wills, L., Millin, T., Bridges, Sarah, Abrams, R. A., Joseph, G., Griffiths, G., Hurt, Chris Nicholas and Staffurth, John Nicholas 2013. The SCALOP Trial Plan Assessment Form (PAF) as a tool for Radiation Therapy Trials Quality Assurance (RTTQA). International Journal of Radiation Oncology*Biology*Physics 87 (2) , S306. 10.1016/j.ijrobp.2013.06.804

Thomas, Betsan M., Smith, Christian, Evans, Jessica, Button, Michael R., Kumar, Satish, Palaniappan, Nachi, Staffurth, John Nicholas, Tanguay, Jacob S. and Lester, Jason F. 2013. Time to prostate specific antigen (PSA) nadir may predict rapid relapse in men with metastatic castration-resistant prostate cancer (CRPC) receiving docetaxel chemotherapy. Medical Oncology 30 (4) , 719. 10.1007/s12032-013-0719-0

Crosby, Thomas David Lewis, Hurt, Chris Nicholas, Falk, Stephen, Gollins, Simon, Mukherjee, Somnath, Staffurth, John Nicholas, Ray, Ruby, Bashir, Nadim, Bridgewater, John A., Geh, J. Ian, Cunningham, David, Blazeby, Jane, Roy, Rajarshi, Maughan, Timothy Stanley and Griffiths, Gareth O. 2013. Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trial. The Lancet Oncology 14 (7) , pp. 627-637. 10.1016/S1470-2045(13)70136-0

Mukherjee, Somnath, Hurt, Chris Nicholas, Bridgewater, John, Falk, Stephen, Cummins, Sebastian, Wasan, Harpreet, Crosby, Thomas David Lewis, Jephcott, Catherine, Roy, Rajarshi, Radhakrishna, Ganesh, McDonald, Alec, Ray, Ruby, Joseph, George, Staffurth, John Nicholas, Abrams, Ross A., Griffiths, Gareth O. and Maughan, Timothy Stanley 2013. Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial. The Lancet Oncology 14 (4) , pp. 317-326. 10.1016/S1470-2045(13)70021-4

Crosby, T., Hurt, Chris Nicholas, Falk, S., Gollins, S., Mukherjee, Saptarshi, Staffurth, John Nicholas, Ray, Ruby, Bashir, N., Bridgwater, J., Geh, J. I., Cunningham, D., Blazeby, J., Roy, R., Maughan, T and Griffiths, Gareth 2013. SCOPE 1: A phase II/III trial of chemoradiotherapy in esophageal cancer plus or minus cetuximab. American Journal of Clinical Oncology 31 (Supp 4) , LBA3. 10.1200/jco.2013.31.4_suppl.lba3

Mukherjee, S., Hurt, Chris Nicholas, Griffiths, G., Bridgewater, J. A., Crosby, T., Falk, S., Cummins, S., Roy, R., Mangar, S., Mcdonald, A., Staffurth, John Nicholas, Abrams, R. A. and Maughan, T. 2013. SCALOP: Results of a randomized phase II study of induction chemotherapy followed by genicitabine (G) or capecitabine (Cap) based chentoradialion (CRT) in locally advanced pancreatic cancer (LANPC). American Journal of Clinical Oncology 31 (Supp 4)

Mukherjee, Somnath, Halle, Charlotte, Spezi, Emiliano, Joseph, George, Mary, Jennifer, Branagan, Rose, Hurt, Chris Nicholas, Falk, Stephen, Nixon, Lisette Sheena, Abrams, Ross A. and Staffurth, John Nicholas 2013. Comparison of investigator-delineated GTV in chemoradiotherapy (CRT) for locally advanced nonmetastatic pancreatic cancer (LANPC): Analysis of the pretrial test case for the SCALOP trial. Journal of Clinical Oncology 31 (4) , 230.

Burnet, N. G., Billingham, L. J., Chan, C. S. K., Hall, E., Macdougall, J., Mackay, R. I., Maughan, Timothy Stanley, Nutting, C. M., Staffurth, John Nicholas and Illidge, T. M. 2012. Methodological considerations in the evaluation of radiotherapy technologies [Editorial]. Clinical Oncology 24 (10) , pp. 707-709. 10.1016/j.clon.2012.06.003

Hummel, S. R., Stevenson, M. D., Simpson, E. L. and Staffurth, John Nicholas 2012. A model of the cost-effectiveness of intensity-modulated radiotherapy in comparison with three-dimensional conformal radiotherapy for the treatment of localised prostate cancer. Clinical Oncology 24 (10) , e159-e167. 10.1016/j.clon.2012.09.003

Gwynne, Sarah Helene, Spezi, Emiliano, Wills, Lucy, Nixon, Lisette Sheena, Hurt, Chris Nicholas, Joseph, George, Evans, Mererid, Griffiths, Gareth O., Crosby, Thomas David Lewis and Staffurth, John Nicholas 2012. Toward semi-automated assessment of target volume delineation in radiotherapy trials: the SCOPE 1 pretrial test case. International Journal of Radiation Oncology*Biology*Physics 84 (4) , pp. 1037-1042. 10.1016/j.ijrobp.2012.01.094

Mayles, W. P. M., Cooper, T., Mackay, R., Staffurth, John Nicholas and Williams, M. 2012. Progress with intensity-modulated radiotherapy implementation in the UK. Clinical Oncology 24 (8) , pp. 543-544. 10.1016/j.clon.2012.06.005

Fizazi, Karim, Scher, Howard I., Molina, Arturo, Logothetis, Christopher J., Chi, Kim N., Jones, Robert J., Staffurth, John Nicholas, North, Scott, Vogelzang, Nicholas J., Saad, Fred, Mainwaring, Paul, Harland, Stephen, Goodman, Oscar B., Sternberg, Cora N., Li, Jin Hui, Kheoh, Thian, Haqq, Christopher M. and de Bono, Johann S, 2012. Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. The Lancet Oncology 13 (10) , pp. 983-992. 10.1016/S1470-2045(12)70379-0

Mackay, R. I., Burnet, N. G., Green, S., Illidge, T. M. and Staffurth, John Nicholas 2012. Radiotherapy physics research in the UK: challenges and proposed solutions. British Journal of Radiology 85 (1018) , pp. 1354-1362. 10.1259/bjr/61530686

Spezi, Emiliano, Downes, Patrick, Jarvis, Richard, Radu, Emil and Staffurth, John Nicholas 2012. Patient-specific three-dimensional concomitant dose from cone beam computed tomography exposure in image-guided radiotherapy. International Journal of Radiation Oncology*Biology*Physics 83 (1) , pp. 419-426. 10.1016/j.ijrobp.2011.06.1972

Nilsson, S., Strang, P., Aksnes, A. K., Franzèn, L., Olivier, P., Pecking, A., Staffurth, John Nicholas, Vasanthan, S., Andersson, C. and Bruland, Ø. S. 2012. A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer. European Journal of Cancer 48 (5) , pp. 678-686. 10.1016/j.ejca.2011.12.023

Dearnaley, David, Syndikus, Isabel, Sumo, Georges, Bidmead, Margaret, Bloomfield, David, Clark, Catharine, Gao, Annie, Hassan, Shama, Horwich, Alan, Huddart, Robert, Khoo, Vincent, Kirkbride, Peter, Mayles, Helen, Mayles, Philip, Naismith, Olivia, Parker, Chris, Patterson, Helen, Russell, Martin, Scrase, Christopher, South, Chris, Staffurth, John Nicholas and Hall, Emma 2012. Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: Preliminary safety results from the CHHiP randomised controlled trial. The Lancet Oncology 13 (1) , pp. 43-54. 10.1016/S1470-2045(11)70293-5

Gwynne, Sarah Helene, Webster, Richard, Adams, Richard Alexander, Mukherjee, Saptarshi, Coles, Bernadette Mary and Staffurth, John Nicholas 2012. Image-guided Radiotherapy for Rectal Cancer - A Systematic Review. Clinical Oncology 24 (4) , pp. 250-260. 10.1016/j.clon.2011.07.012

Gwynne, Sarah Helene, Mukherjee, Saptarshi, Webster, Richard, Spezi, Emiliano, Staffurth, John Nicholas, Coles, Bernadette Mary and Adams, Richard Alexander 2012. Imaging for Target Volume Delineation in Rectal Cancer Radiotherapy - A Systematic Review. Clinical Oncology 24 (1) , pp. 52-63. 10.1016/j.clon.2011.10.001

Gwynne, S., Spezi, Emiliano, Staffurth, John Nicholas, Palaniappan, N., Wills, L., Hurt, Chris Nicholas, Nixon, Lisette Sheena, Evans, M., Griffiths, G. and Crosby, T. 2011. Inter-observer variation in outlining of pre-trial test case in the SCOPE1 trial: A United Kingdom definitive chemoradiotherapy trial for esophageal cancer. International Journal of Radiation Oncology - Biology - Physics 81 (2) , S67-S68. 10.1016/j.ijrobp.2011.06.135

de Bono, Johann S., Logothetis, Christopher J., Molina, Arturo, Fizazi, Karim, North, Scott, Chu, Luis, Chi, Kim N., Jones, Robert J., Goodman, Oscar B., Saad, Fred, Staffurth, John Nicholas, Mainwaring, Paul, Harland, Stephen, Flaig, Thomas W., Hutson, Thomas E., Cheng, Tina, Patterson, Helen, Hainsworth, John D., Ryan, Charles J., Sternberg, Cora N., Ellard, Susan L., Fléchon, Aude, Saleh, Mansoor, Scholz, Mark, Efstathiou, Eleni, Zivi, Andrea, Bianchini, Diletta, Loriot, Yohann, Chieffo, Nicole, Kheoh, Thian, Haqq, Christopher M. and Scher, Howard I. 2011. Abiraterone and increased survival in metastatic prostate cancer. New England Journal of Medicine 364 (21) , pp. 1995-2005. 10.1056/NEJMoa1014618

Gwynne, S., Webster, R., Mukherjee, S., Staffurth, John Nicholas, Spezi, Emiliano and Adams, R. 2011. Imaging for rectal cancer radiotherapy - a systematic review. Clinical Oncology 23 (3) , S37-S37.

Tabi, Zsuzsanna, Spary, Lisa Kate, Coleman, Sharon Louise, Clayton, Aled, Mason, Malcolm David and Staffurth, John Nicholas 2010. Resistance of CD45RA- T cells to apoptosis and functional impairment, and activation of tumor-antigen specific T cells during radiation therapy of prostate cancer. The Journal of Immunology 185 (2) , pp. 1330-1339. 10.4049/jimmunol.1000488

Welton, Joanne L., Khanna, Sanjay, Giles, Peter James, Brennan, Paul, Brewis, Ian Andrew, Staffurth, John Nicholas, Mason, Malcolm David and Clayton, Aled 2010. Proteomics analysis of bladder cancer exosomes. Molecular & Cellular Proteomics 9 (6) , pp. 1324-1338. 10.1074/mcp.M000063-MCP201

Mukherjee, S., Hurt, Chris Nicholas, Griffiths, G., Crosby, T. S., Staffurth, John Nicholas, Bridges, Sarah, Bridgewater, J. A., Mcdonald, A., Falk, S. and Maughan, Timothy Stanley 2010. A Cancer Research UK multicenter randomized phase II study of induction chemotherapy followed by gemcitabine- or capecitabine-based chemoradiotherapy for locally advanced nonmetastatic pancreatic cancer. American Journal of Clinical Oncology 28

Guerrero Urbano, T., Khoo, V., Staffurth, John Nicholas, Norman, A., Buffa, F., Jackson, A., Adams, E., Hansen, V., Clark, C., Miles, E., McNair, H., Nutting, C., Parker, C., Eeles, R., Huddart, R., Horwich, A. and Dearnaley, D. P. 2010. Intensity-modulated radiotherapy allows escalation of the radiation dose to the pelvic lymph nodes in patients with locally advanced prostate cancer: preliminary results of a phase I dose escalation study. Clinical Oncology 22 (3) , pp. 236-244. 10.1016/j.clon.2010.01.005

Routsis, D., Staffurth, John Nicholas, Beardmore, C. and Mackay, R. 2010. Education and training for intensity-modulated radiotherapy in the UK. Clinical Oncology 22 (8) , pp. 675-680. 10.1016/j.clon.2010.06.012

Staffurth, John Nicholas 2010. A review of the clinical evidence for intensity-modulated radiotherapy. Clinical Oncology 22 (8) , pp. 643-657. 10.1016/j.clon.2010.06.013

Williams, M. V., Cooper, T., Mackay, R., Staffurth, John Nicholas, Routsis, D. and Burnet, N. 2010. The implementation of intensity-modulated radiotherapy in the UK. Clinical Oncology 22 (8) , pp. 623-628. 10.1016/j.clon.2010.06.015

Mackay, R. I., Staffurth, John Nicholas, Poynter, A. and Routsis, D. 2010. UK guidelines for the safe delivery of intensity-modulated radiotherapy. Clinical Oncology 22 (8) , pp. 629-635.

Button, Michael Robert and Staffurth, John Nicholas 2010. Clinical Application of Image-guided Radiotherapy in Bladder and Prostate Cancer. Clinical Oncology 22 (8) , pp. 698-706. 10.1016/j.clon.2010.06.020

Jones, C. E., Mason, Malcolm David, Brown, Paul, Staffurth, John Nicholas and Smith, C. 2009. The development and introduction of a written post-radiotherapy information leaflet for prostate cancer patients [Abstract]. Clinical Oncology 21 (3) , p. 270. 10.1016/j.clon.2009.01.001

Nixon, Lisette Sheena, Wills, Lauren, Staffurth, John Nicholas, Crosby, Thomas David Lewis, Casbard, Angela C. and Griffiths, G. 2009. Implementation of a QA RT substudy for SCOPE 1; Preliminary results for test cases [Abstract]. Clinical Oncology 21 (3) , p. 255. 10.1016/j.clon.2009.01.001,

Shelley, M. D., Kumar, S., Wilt, T., Staffurth, John Nicholas, Coles, Bernadette Mary and Mason, Malcolm David 2009. A systematic review and meta-analysis of randomised trials of neo-adjuvant hormone therapy for localised and locally advanced prostate carcinoma. Cancer Treatment Reviews 35 (1) , pp. 9-17. 10.1016/j.ctrv.2008.08.002

Mitchell, Philip J., Welton, Joanne L., Staffurth, John Nicholas, Court, Jacquelyn, Mason, Malcolm David, Tabi, Zsuzsanna and Clayton, Aled 2009. Can urinary exosomes act as treatment response markers in prostate cancer? Journal Of Translational Medicine 7 (4) , n/a. 10.1186/1479-5876-7-4

Gwynne, Sarah, Wills, Lauren, Joseph, Giannina, John, G., Staffurth, John Nicholas, Hurt, Chris Nicholas and Mukherjee, Saptarshi 2009. Respiratory movement of upper abdominal organs and its effect on radiotherapy planning in pancreatic cancer1. Clinical Oncology 21 (9) , pp. 713-719. 10.1016/j.clon.2009.07.015

Shelley, M. D., Kumar, S., Coles, Bernadette Mary, Wilt, T., Staffurth, John Nicholas and Mason, Malcolm David 2009. Adjuvant hormone therapy for localised and locally advanced prostate carcinoma: a systematic review and meta-analysis of randomised trials. Cancer Treatment Reviews 35 (7) , pp. 540-546. 10.1016/j.ctrv.2009.05.001

Wills, Lucy, Millin, Anthony, Paterson, Jennifer, Crosby, Thomas David Lewis and Staffurth, John Nicholas 2009. The effect of planning algorithms in oesophageal radiotherapy in the context of the SCOPE 1 trial. Radiotherapy and Oncology 93 (3) , pp. 462-467. 10.1016/j.radonc.2009.08.036

Sutcliffe, P., Hummel, S., Simpson, E., Young, T., Rees, A., Wilkinson, A., Hamdy, F., Clarke, N. and Staffurth, John Nicholas 2009. Use of classical and novel biomarkers as prognostic risk factors for localised prostate cancer: a systematic review. Health Technology Assessment 13 (5) , pp. 1-242. 10.3310/hta13050

Hudson, E., Kynaston, Howard, Varma, Muralidharan, Carter, A., Staffurth, John Nicholas, Barber, Jim, Mason, Malcolm David and Lester, Jason Francis 2008. Radiotherapy after radical prostatectomy for adenocarcinoma of the prostate: a UK institutional experience and review of published studies. Clinical Oncology 20 (5) , pp. 353-357. 10.1016/j.clon.2008.02.008

Abraham, Jacinta and Staffurth, John Nicholas 2008. Hormonal therapy for cancer. Medicine 36 (1) , pp. 29-32. 10.1016/j.mpmed.2007.10.010

Abraham, Jacinta and Staffurth, John Nicholas 2008. Hormones in cancer. In: Hanna, C. Louise, Crosby, Tom and Macbeth, Fergus Robert eds. Practical clinical oncology, Cambridge: Cambridge University Press, pp. 23-38.

Barber, Jim and Staffurth, John Nicholas 2008. Prostate. In: Hanna, C. Louise, Crosby, Tom and Macbeth, Fergus Robert eds. Practical clinical oncology, Cambridge: Cambridge University Press, pp. 231-239.

Barber, Jim and Staffurth, John Nicholas 2008. Testis. In: Hanna, C. Louise, Crosby, Tom and Macbeth, Fergus Robert eds. Practical clinical oncology, Cambridge: Cambridge University Press, pp. 240-251.

Staffurth, John Nicholas and Mason, Malcolm David 2008. Radiotherapy for early prostate cancer. In: Kirk, David ed. International handbook of prostate cancer. 3rd ed, Hampshire: Euromed Communications Limited, pp. 161-182.

Harnden, P., Shelley, M. D., Coles, Bernadette Mary, Staffurth, John Nicholas and Mason, Malcolm David 2007. Should the Gleason grading system for prostate cancer be modified to account for high-grade tertiary components? A systematic review and meta-analysis. The Lancet Oncology 8 (5) , pp. 411-419. 10.1016/S1470-2045(07)70136-5