Browse by Current Cardiff authors

Singh, Ravinder K., Malosse, Camille, Davies, Joanne, Malissen, Bernard, Kochba, Efrat, Levin, Yotam, Birchall, James C., Coulman, Sion A, Mous, Jan, McAteer, Martina A., Dayan, Colin M., Henri, Sandrine and Wong, F. Susan 2021. Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides. Nanomedicine: Nanotechnology, Biology and Medicine 32 , 102321. 10.1016/j.nano.2020.102321 Item availability restricted.

Ingrole, Rohan S.J., Azizoglu, Erkan, Dul, Maria, Birchall, James C., Gill, Harvinder S. and Prausnitz, Mark R. 2021. Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity. Biomaterials 267 , 120491. 10.1016/j.biomaterials.2020.120491 Item availability restricted.

Bolton, Chris J. W., Howells, Olivia, Blayney, Gareth J., Eng, Pey F., Birchall, James C., Gualeni, Benedetta, Roberts, Kerry, Ashraf, Huma and Guy, Owen J. 2020. Hollow silicon microneedle fabrication using advanced plasma etch technologies for applications in transdermal drug delivery. Lab on a Chip 20 (15) , pp. 2788-2795. 10.1039/D0LC00567C

Arikat, Farah, Hanna, Stephanie J., Singh, Ravinder K., Vilela, Luciano, Wong, F. Susan, Dayan, Colin M., Coulman, Sion A. and Birchall, James C. 2020. Targeting proinsulin to local immune cells using an intradermal microneedle delivery system; a potential antigen-specific immunotherapy for type 1 diabetes. Journal of Controlled Release 322 , pp. 593-601. 10.1016/j.jconrel.2020.02.031 Item availability restricted.

Ayre, Wayne Nishio, Scully, Nicole, Elford, Carole, Evans, Bronwen AJ, Rowe, Wendy, Rowlands, Jeff, Mitha, Ravi, Malpas, Paul, Manti, Panagiota, Holt, Cathy, Morgan-Jones, Rhidian, Birchall, James, Denyer, Stephen P and Evans, Sam L 2020. Alternative radiopacifiers for polymethyl methacrylate bone cements: Silane-treated anatase titanium dioxide and yttria-stabilised zirconium dioxide. Journal of Biomaterials Applications Item availability restricted.

Maarifi, Ghizlane, Czubala, Magdalena, Lagisquet, Justine, Ivory, Matthew, Fuchs, Kyra, Papin, Laure, Birchall, James C., Nisole, Sebastien, Piguet, Vincent and Blanchet, Fabien P. 2019. Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells. Cellular and Molecular Immunology 17 , pp. 547-549. 10.1038/s41423-019-0302-5

Dul, M., Nikolic, T., Stefanidou, M., McAteer, M.A., Williams, P., Mous, J., Roep, B.O., Kochba, E., Levin, Y., Peakman, M., Wong, F.S., Dayan, C.M., Tatovic, D., Coulman, S.A. and Birchall, J.C. 2019. Conjugation of a peptide autoantigen to gold nanoparticles for intradermally administered antigen specific immunotherapy. International Journal of Pharmaceutics 562 , pp. 303-312. 10.1016/j.ijpharm.2019.03.041

Price, Annie, Rai, Simran, McLeod, Robert, Birchall, James C. and Elhassan, Hassan 2018. Topical propranolol for infantile haemangiomas: A systematic review. Journal of the European Academy of Dermatology and Venereology 32 (12) , pp. 2083-2089. 10.1111/jdv.14963

Gualeni, B., Coulman, S. A., Shah, D., Eng, P.F., Ashraf, H., Vescovo, P., Blayney, G.J., Piveteau, L.-D., Guy, O.J. and Birchall, J.C. 2018. Minimally-invasive and targeted therapeutic cell delivery to the skin using microneedle devices. British Journal of Dermatology 178 (3) , pp. 731-739. 10.1111/bjd.15923

Davies, Lleucu, Gateley, Christopher, Holland, Phillip, Coulman, Sion and Birchall, James 2018. Accelerating topical anaesthesia using microneedles. Skin Pharmacology and Physiology 30 (6) , pp. 277-283. 10.1159/000479530

Moreno, Esther, Schwartz, Juana, Calvo, Alba, Blanco, Laura, Larrea, Esther, Irache, Juan M, Sanmartín, Carmen, Coulman, Sion A, Soto, Manuel, Birchall, James C and Espuelas, Socorro 2017. Skin vaccination using microneedles coated with a plasmid DNA cocktail encoding nucleosomal histones of Leishmania spp. International Journal of Pharmaceutics 533 (1) , pp. 236-244. 10.1016/j.ijpharm.2017.09.055

Dul, M., Stefanidou, M.., Porta, P., Serve, J., O'Mahony, C., Malissen, B., Henri, S., Levin, Y., Kochba, E., Wong, F.S., Dayan, C., Coulman, S.A. and Birchall, J.C. 2017. Hydrodynamic gene delivery in human skin using a hollow microneedle device. Journal of Controlled Release 265 , pp. 120-131. 10.1016/j.jconrel.2017.02.028

Zhao, Xin, Coulman, Sion A., Hanna, Stephanie J., Wong, F. Susan, Dayan, Colin M. and Birchall, James C. 2017. Formulation of hydrophobic peptides for skin delivery via coated microneedles. Journal of Controlled Release 265 , pp. 2-13. 10.1016/j.jconrel.2017.03.015

McGrath, Marie, Coulman, Sion, Birchall, James C. and Prausnitz, Mark 2017. Editorial. Journal of Controlled Release 265 , p. 1. 10.1016/j.jconrel.2017.10.030

Martin, Christopher, Alcock, Natalie, Hiom, Sarah and Birchall, James C. 2017. Development and evaluation of topical gabapentin formulations. Pharmaceutics 9 (3) , p. 31. 10.3390/pharmaceutics9030031

Jones, Brian, Ecenarro, Susana, Whiteside, Ben, Birchall, James and Coulman, Sion 2017. Imaging techniques for dry powder inhaler capsules. Inhalation

Nishio Ayre, Wayne, Birchall, James C., Evans, Samuel L. and Denyer, Stephen P. 2016. A novel liposomal drug delivery system for PMMA bone cements. Journal of Biomedical Materials Research Part B: Applied Biomaterials 104 (8) , pp. 1510-1524. 10.1002/jbm.b.33488

Czubala, Magdalena A., Finsterbusch, Katja, Ivory, Matthew O., Mitchell, J. Paul, Ahmed, Zahra, Shimauchi, Takatoshi, Karoo, Richard O. S., Coulman, Sion A., Gateley, Christopher, Birchall, James C., Blanchet, Fabien P. and Piguet, Vincent 2016. TGFβ induces a SAMHD1-independent post-entry restriction to HIV-1 infection of human epithelial Langerhans cells. Journal of Investigative Dermatology 136 (10) 10.1016/j.jid.2016.05.123

Caucheteux, Stephan M., Mitchell, John P., Ivory, Matthew O., Hirosue, Sachiko, Hakobyan, Svetlana, Dolton, Garry, Ladell, Kristin, Miners, Kelly, Price, David A., Kan-Mitchell, June, Sewell, Andrew K., Nestle, Frank, Moris, Arnaud, Karoo, Richard O., Birchall, James C., Swartz, Melody A., Hubbel, Jeffrey A., Blanchet, Fabien P. and Piguet, Vincent 2016. Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. Journal of Investigative Dermatology 136 (6) , pp. 1172-1181. 10.1016/j.jid.2016.01.033

Teagle, Alexandra R., Birchall, James Caradoc and Hargest, Rachel 2016. Gene therapy for pyoderma gangrenosum: optimal transfection conditions and effect of drugs on gene delivery in the HaCaT cell line using cationic liposomes. Skin Pharmacology and Physiology 29 , pp. 119-129. 10.1159/000444859

Chong, Rosalind Hui, Jones, Brian, Díez, Fernando, Birchall, James Caradoc and Coulman, Sion 2016. Evaluating the sensitivity, reproducibility and flexibility of a method to test hard shell capsules intended for use in dry powder inhalers. International Journal of Pharmaceutics 500 (1-2) , pp. 316-325. 10.1016/j.ijpharm.2016.01.034

Zhao, Xin, Birchall, James C., Coulman, Sion A., Tatovic, Danijela, Singh, Ravinder K., Wen, Li, Wong, F. Susan, Dayan, Colin M. and Hanna, Stephanie J. 2016. Microneedle delivery of autoantigen for immunotherapy in type 1 diabetes. Journal of Controlled Release 223 , pp. 178-187. 10.1016/j.jconrel.2015.12.040

Alhadj Ali, Mohammad, Thrower, Sally L., Hanna, Stephanie J., Coulman, Sion A., Birchall, James C., Wong, F. Susan, Dayan, Colin Mark and Tatovic, Danijela 2015. Topical steroid therapy induces pro-tolerogenic changes in Langerhans cells in human skin. Immunology 146 (3) , pp. 411-422. 10.1111/imm.12518

Choi, Heungjae, Naylon, Jack, Luzio, Steve, Buetler, Jan, Birchall, James, Martin, Chris and Porch, Adrian 2015. Design and in vitro interference test of microwave noninvasive blood glucose monitoring sensor. IEEE Transactions on Microwave Theory and Techniques 63 (10) , pp. 3016-3025. 10.1109/TMTT.2015.2472019

Ivory, Matthew Owen, Birchall, James Caradoc and Piguet, Vincent 2015. Early dengue virus infection in human skin: a cycle of inflammation and infectivity [Commentary]. Journal of Investigative Dermatology 135 (7) , pp. 1711-1712. 10.1038/jid.2014.544

Rattanapak, Teerawan, Birchall, James Caradoc, Young, Katherine, Kubo, Atsuko, Fujimori, Sayumi, Ishii, Masaru and Hook, Sarah 2014. Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization. PLOS ONE 9 (2) , e89503. 10.1371/journal.pone.0089503

Rattanapak, Teerawan, Birchall, James Caradoc, Young, Katherine, Ishii, Masaru, Meglinski, Igor, Rades, Thomas and Hook, Sarah 2013. Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy. Journal of Controlled Release 172 (3) , pp. 894-903. 10.1016/j.jconrel.2013.08.018

Pearton, Marc, Pirri, Daniela, Kang, Sang-Moo, Compans, Richard W. and Birchall, James Caradoc 2013. Host responses in human skin after conventional intradermal injection or microneedle administration of virus-like-particle influenza vaccine. Advanced Healthcare Materials 2 (10) , pp. 1401-1410. 10.1002/adhm.201300006

Chong, Rosalind, Gonzalez-Gonzalez, E., Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion, Hargest, Rachel and Birchall, James Caradoc 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166 (3) , pp. 211-219. 10.1016/j.jconrel.2012.12.030

Tatovic, Danijela, Pearton, Marc, Birchall, James Caradoc, Wong, S. and Dayan, Colin Mark 2013. Topical steroid has the potential of modulating skin dendritic cells to tolerogenic antigen presenting cells in human organ skin bath culture [Abstract]. Diabetic Medicine 30 (s1) , p. 53. 10.1111/dme.12091_1

Groves, Rachel Beth, Coulman, Sion, Birchall, James Caradoc and Evans, Samuel Lewin 2013. An anisotropic, hyperelastic model for skin: experimental measurements, finite element modelling and identification of parameters for human and murine skin. Journal of the Mechanical Behaviour of Biomedical Materials 18 , pp. 167-180. 10.1016/j.jmbbm.2012.10.021

Torrisi, Barbara Maria, Zarnitsyn, V., Prausnitz, M. R., Anstey, Alexander Vincent, Gateley, Christopher, Birchall, James Caradoc and Coulman, Sion 2013. Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin. Journal of Controlled Release 165 (2) , pp. 146-152. 10.1016/j.jconrel.2012.11.010

Torrisi, Barbara Maria, Birchall, James Caradoc, Jones, Brian, Díez, Fernando and Coulman, Sion 2013. The development of a sensitive methodology to characterise hard shell capsule puncture by dry powder inhaler pins. International Journal of Pharmaceutics 456 (2) , pp. 545-552. 10.1016/j.ijpharm.2013.08.011

Chong, Rosalind H.E., Gonzalez-Gonzalez, Emilio, Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion A., Hargest, Rachel and Birchall, James C. 2013. Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. Journal of Controlled Release 166 (3) , p. 211. 10.1016/j.jconrel.2012.12.030

Yildiz, Ayca, John, Elinor, Özsoy, Yildiz, Araman, Ahmet, Birchall, James Caradoc, Broadley, Kenneth John and Gumbleton, Mark 2012. Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation. Journal of Controlled Release 162 (2) , pp. 456-463. 10.1016/j.jconrel.2012.07.008

Birchall, James Cardaoc 2012. Overcoming the stratum corneum barrier: microneedle delivery of macromolecules and vaccines [Abstract]. International Journal of Cosmetic Science 34 (4) , p. 361. 10.1111/j.1468-2494.2012.00720.x

Pearton, Marc, Saller, Verena, Coulman, Sion, Gateley, Chris, Anstey, Alexander Vincent, Zarnitsyn, Vladimir and Birchall, James Caradoc 2012. Microneedle delivery of plasmid DNA to living human skin: Formulation coating, skin insertion and gene expression. Journal of Controlled Release 160 (3) , pp. 561-569. 10.1016/j.jconrel.2012.04.005

Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Morrissey, A. and Birchall, James Caradoc 2012. Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications. Journal of Controlled Release 158 (1) , pp. 93-101. 10.1016/j.jconrel.2011.10.024

Groves, Rachel Beth, Coulman, Sion, Birchall, James Caradoc and Evans, Samuel Lewin 2012. Quantifying the mechanical properties of human skin to optimise future microneedle device design. Computer Methods in Biomechanics and Biomedical Engineering 15 (1) , pp. 73-82. 10.1080/10255842.2011.596481

Gonzalez-Gonzalez, E., Kim, Y. C., Speaker, T. J., Hickerson, R. P., Spitler, R., Birchall, James Caradoc, Lara, M. F., Hu, R. H., Liang, Y. H, Kirkiles-Smith, N., Prausnitz, M. R., Milstone, L. M., Contag, C. H. and Kaspar, R. L. 2011. Visualization of plasmid delivery to keratinocytes in mouse and human epidermis. Scientific Reports 1 , p. 158. 10.1038/srep00158

Chong, Rosalind, Coulman, Sion, Saller, V., Pearton, Marc, Shah, A., Hargest, Rachel and Birchall, James Caradoc 2011. Nucleic acid delivery to skin for the potential treatment of dermatopathogenic conditions [Abstract]. Human Gene Therapy 22 (10) , A82-A82.

Teagle, Alexandra, Birchall, James Caradoc and Hargest, Rachel 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes. Human Gene Therapy 22 (10) , A94-A94.

Smith, Mathew W., Birchall, James Caradoc and Coulman, Sion 2011. The wider contribution of microbiology to the pharmaceutical sciences. In: Denver, Stephen P., Hodges, Norman, Gorman, Sean P. and Gilmore, Brendan F. eds. Hugo and Russell's Pharmaceutical Microbiology 8th Edition, Wiley-Blackwell, pp. 463-482.

Teagle, Alexandra, Birchall, James Caradoc and Hargest, Rachel 2011. The effect of drugs commonly used for pyoderma gangrenosum on the efficiency of gene transfer to human keratinocytes [Abstract]. British Journal of Surgery 98 , p. 40. 10.1002/bjs.7577/abstract

Birchall, James Caradoc, Clemo, Rachel Nerys, Anstey, Alexander Vincent and John, David Neale 2011. Microneedles in clinical practice- an exploratory study into the opinions of healthcare professionals and the public. Pharmaceutical Research 28 (1) , pp. 95-106. 10.1007/s11095-010-0101-2

Coulman, Sion, Birchall, James Caradoc, Alex, Aneesh, Pearton, Marc, Hofer, Bernd, O'Mahony, Conor, Drexler, Wolfgang and Považay, Boris 2011. In vivo, in situ imaging of microneedle insertion into the skin of human volunteers using optical coherence tomography. Pharmaceutical Research 28 (1) , pp. 66-81. 10.1007/s11095-010-0167-x

Groves, Rachel Beth, Coulman, Sion, Birchall, James Caradoc and Evans, Samuel Lewin 2011. Using inverse finite element modeling to identify the anisotropic mechanical properties of human and mouse skin in tension. Presented at: International Conference on the Mechanics of Biomaterials and Tissues, Hawaii, USA, 11-15 December 2011.

Pearton, Marc, Kang, S. M., Song, J. M., Kim, Y. C., Quan, F. S., Ivory, M., Prausnitz, M. R., Compans, R. W. and Birchall, James Caradoc 2010. Immune stimulation following microneedle delivery of influenza virus-like particle (VLP) vaccines to human skin [Abstract]. Drug Discovery Today 15 (23-24) , p. 1111.

Song, J. M., Kim, Y. C., Lipatov, A. S., Pearton, Marc, Davis, C. T., Yoo, D. G., Park, K. M., Chen, L. M., Quan, F. S., Birchall, James Caradoc, Donis, R. O., Prausnitz, M. R., Compans, R. W. and Kang, S. M. 2010. Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-Cell responses in mice. Clinical and Vaccine Immunology 17 (9) , pp. 1381-1389. 10.1128/CVI.00100-10

Pearton, Marc, Kang, S. M., Song, J. M., Anstey, Alexander Vincent, Ivory, Matthew Owen, Compans, R. W. and Birchall, James Caradoc 2010. Changes in human Langerhans cells following intradermal injection of influenza virus-like particle vaccines. PLoS ONE 5 (8) , e12410. 10.1371/journal.pone.0012410

Pearton, Marc, Kang, Sang-Moo, Song, Jae-Min, Kim, Yeu-Chun, Quan, Fu-Shi, Anstey, Alexander Vincent, Ivory, Matthew Owen, Prausnitz, Mark, Compans, Richard and Birchall, James Caradoc 2010. Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin. Vaccine 28 (37) , pp. 6104-6113. 10.1016/j.vaccine.2010.05.055

Bains, Baljinder Kaur, Birchall, James Caradoc, Toon, Richard and Taylor, Glyn 2010. In vitro reporter gene transfection via plasm ID DNA delivered by metered dose inhaler. Journal of Pharmaceutical Sciences 99 (7) , pp. 3089-3099. 10.1002/jps.22085

Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Hodson, D. and Birchall, James 2010. Biodegradable sugar glass microneedles for macromolecular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 799. 10.1211/jpp.62.06.0016

Ng, K. W., Pearton, Marc, Allender, Christopher John, Morrissey, A., McLoughlin, P. and Birchall, James Caradoc 2010. Biodegradable microneedles for intra-epidermal vaccination [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 798. 10.1211/jpp.62.06.0016

Ng, Keng Wooi, Pearton, Marc, Coulman, Sion, Anstey, Alexander Vincent, Gateley, Christopher, Morrissey, Anthony, Allender, Christopher John and Birchall, James Caradoc 2009. Development of an ex vivo human skin model for intradermal vaccination: Tissue viability and Langerhans cell behaviour. Vaccine 27 (43) , pp. 5948-5955. 10.1016/j.vaccine.2009.07.088

Ng, Keng Wooi, Pearton, Marc, Coulman, Sion, Anstey, Alexander Vincent, Gateley, C., Morrissey, A., O’Mahony, C., Allender, Christopher John and Birchall, James Cardoc 2009. Tissue viability and Langerhans cell behaviour in an ex-vivo human skin model for cutaneous DNA vaccination [Abstract]. Journal of Pharmacy and Pharmacology 61 (S1) , A1-A5. 10.1211/002235709789037044

Coulman, Sion, Anstey, Alexander Vincent, Gateley, Christopher, Morrissey, Anthony, McLoughlin, Peter, Allender, Christopher John and Birchall, James Caradoc 2009. Microneedle mediated delivery of nanoparticles into human skin. International Journal of Pharmaceutics 366 (1-2) , pp. 190-200. 10.1016/j.ijpharm.2008.08.040

Haq, Mohammed-Innam-Ul, Pearton, Marc, Kalavala, Manjunatha, Anstey, Alexander Vincent, O'Mahony, C., Porter, R., John, David Neale and Birchall, James Caradoc 2009. Penetration and wound-healing responses following application of microneedles and hypodermic needles to human volunteers. Journal of Pharmacy and Pharmacology 61 (S1)

Ng, Keng Wooi, Pearton, Marc, Coulman, Sion, Anstey, Alexander Vincent, Gateley, C., Morrissey, A., Allender, Christopher John and Birchall, James Caradoc 2009. Ex vivo immunological studies using excised human skin. British Journal Of Dermatology 160 (4) , p. 921.

Haq, Mohammed Inaam-Ul, Smith, E., John, David Neale, Kalavala, Manjunatha, Edwards, C., Anstey, Alexander Vincent, Morrissey, A. and Birchall, James Caradoc 2009. Clinical administration of microneedles: skin puncture, pain and sensation. Biomedical Microdevices 11 (1) , pp. 35-47. 10.1007/s10544-008-9208-1

Pearton, Marc, Allender, Christopher John, Brain, Keith Roger, Anstey, Alexander Vincent, Gateley, Chris, Wilke, Nicolle, Morrissey, Anthony and Birchall, James Caradoc 2008. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharmaceutical Research 25 (2) , pp. 407-416. 10.1007/s11095-007-9360-y

Birchall, James Caradoc, Jones, Brian and Morrissey, A. 2008. A comparison of the puncturing properties of gelatin and hypromellose capsules for use in dry powder inhalers. Drug Development and Industrial Pharmacy 34 (8) , pp. 870-876. 10.1080/03639040801928903

Bains, Baljunder Kaur, Taylor, Glyn, Toon, R. and Birchall, James Caradoc 2007. Novel nanoparticles for pulmonary gene delivery [Abstract]. Pharmacy and Pharmacology 59 (S1) , A31-A32. 10.1211/002235707781850140

Collins, Elizabeth, Birchall, James Caradoc, Williams, Julie L. and Gumbleton, Mark 2007. Nuclear localisation and pDNA condensation in non-viral gene delivery. The Journal of Gene Medicine 9 (4) , pp. 265-274. 10.1002/jgm.1015

Haq, Mohammed Inaam-Ul, Smith, E., Edwards, C., Kalavala, Manjunatha, Anstey, Alexander Vincent, Morrissey, A., John, David John and Birchall, James Caradoc 2007. An assessment of pain, penetration efficiency and trans-epidermal water loss in human subjects following application of microfabricated microneedle arrays [Abstract]. Journal of Pharmacy and Pharmacology 59 (S1) , A54. 10.1211/002235707781850168

Birchall, James Caradoc 2007. Pulmonary delivery of nucleic acids. Expert Opinion on Drug Delivery 4 (6) , pp. 575-578. 10.1517/17425247.4.6.575

Seville, P. C., Learoyd, T. P., Li, H. Y., Williamson, I. J. and Birchall, James Caradoc 2007. Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery. Powder Technology 178 (1) , pp. 40-50. 10.1016/j.powtec.2007.03.046

Li, H.-Y. and Birchall, James Caradoc 2006. Chitosan-modified dry powder formulations for pulmonary gene delivery. Pharmaceutical Research 23 (5) , pp. 941-950. 10.1007/s11095-006-0027-x

Birchall, James Caradoc, Coulman, Sion, Anstey, Alexander Vincent, Gateley, Chris, Sweetland, Helen Margaret, Gershonowitz, Amikam, Neville, Lewis and Levin, Galit 2006. Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation. International Journal of Pharmaceutics 312 (1-2) , pp. 15-23. 10.1016/j.ijpharm.2005.12.036

Coulman, Sion, Barrow, David Anthony, Anstey, Alexander Vincent, Gateley, Chris, Morrissey, Anthony, Wilke, Nicolle, Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc 2006. Minimally invasive cutaneous delivery of macromolecules and plasmid DNA via microneedles. Current drug delivery 3 (1) , pp. 65-75.

Pearton, Marc, Gateley, C., Anstey, Alexander Vincent, Wilke, N., Morrissey, A., Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc 2006. Microneedle facilitated delivery of pDNA encoding HBsAg to human skin: potential for genetic vaccination [Abstract]. Journal of Pharmacy and Pharmacology 58 (S1) , A65. 10.1211/002235706778251483

Pearton, Marc, Barrow, Denise, Gateley, C., Anstey, Alexander Vincent, Wilke, N., Morrissey, A., Allender, Christopher John, Brain, Keith Roger and Birchall, James Caradoc 2005. Hydrogels based on PLGA-PEG-PLGA triblock co-polymers as sustained release reservoirs for the delivery of pDNA to microneedle treated human skin [Abstract]. Journal of Pharmacy and Pharmacology 57 (S1) , S83-S84. 10.1211/002235705778248352

Li, H.-Y., Jeans, Christopher, Birchall, James Caradoc and Taylor, Glyn 2005. Nanoparticles for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 57 (S1) , S20. 10.1211/002235705778248569

Birchall, James Caradoc, Coulman, Sion, Pearton, Marc, Allender, Christopher John, Brain, Keith Roger, Anstey, Alexander Vincent, Gateley, Chris, Wilke, Nicolle and Morrissey, Anthony 2005. Cutaneous DNA delivery and gene expression in ex vivo human skin explants via wet-etch microfabricated microneedles. Journal of drug targeting 13 (7) , pp. 415-421. 10.1080/10611860500383705

Li, H.-Y., Seville, P. C., Williamson, I. J. and Birchall, James Caradoc 2005. The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy. The Journal of Gene Medicine 7 (8) , pp. 1035-1043. 10.1002/jgm.749

Li, H.-Y., Seville, P. C., Williamson, I. J. and Birchall, James Caradoc 2004. Dispersibility of spray-dried formulations for pulmonary drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 56 (S1) , S10. 10.1211/002235704777489375

Coulman, S. A., Allender, Christopher John, Barrow, Denise, Gateley, C., Anstey, Alexander Vincent and Birchall, James Caradoc 2004. Microneedle facilitated cutaneous delivery of a non-viral gene complex to the viable epidermis [Abstract]. Journal of Pharmacy and Pharmacology 56 (S1) , S10-S11. 10.1211/002235704777489375

Birchall, James Caradoc, Bouris, K, Chabri, F and Jones,T, 2004. Microfabricated silicon microneedles for nonviral cutaneous gene delivery. British Journal of Dermatology 150 (5) , pp. 869-877. 10.1111/j.1365-2133.2004.05921.x

Birchall, James Caradoc, Kellaway, IW and Seville, PC 2002. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. The Journal of Gene Medicine 4 (4) , pp. 428-437. 10.1002/jgm.282

Birchall, James Caradoc, Waterworth, C. A., Luscombe, C., Parkins, D. A. and Gumbleton, Mark 2001. Statistical modelling of the formulation variables in non-viral gene delivery systems. Journal of Drug Targeting 9 (3) , pp. 169-184. 10.3109/10611860108997926

Ramsay, Euan, Hadgraft, Jon, Birchall, James Caradoc and Gumbleton, Mark 2000. Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro. International Journal of Pharmaceutics 210 (1-2) , pp. 97-107. 10.1016/S0378-5173(00)00571-8

Birchall, James Caradoc, Marichal, C., Campbell, L., Alwan, A., Hadgraft, J. and Gumbleton, Mark 2000. Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes. International Journal of Pharmaceutics 197 (1-2) , pp. 233-238. 10.1016/S0378-5173(00)00336-7

Birchall, James Caradoc, Kellaway, I. W. and Gumbleton, Mark 2000. Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes. International Journal of Pharmaceutics 197 (1-2) , pp. 221-231. 10.1016/S0378-5173(00)00339-2