ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 16.
| Besneux, Matthieu, Greenshields Watson, Alexander, Scurr, Martin, MacLachlan, Bruce, Christian, Adam, Davies, Michael, Hargest, Rachel, Phillips, Simon, Godkin, Andrew and Gallimore, Awen 2018. The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design. Cancer Immunology, Immunotherapy 10.1007/s00262-018-2266-1 |
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Hughes, Ellyn, Scurr, Martin, Campbell, Emma, Jones, Emma, Godkin, Andrew and Gallimore, Awen
2018.
T‐cell modulation by cyclophosphamide for tumour therapy.
Immunology
154
(1)
, pp. 62-68.
10.1111/imm.12913
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Scurr, Martin, Pembroke, Thomas, Bloom, Anja, Roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard, Brewster, Alison, Jones, Robert, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa, Hills, Robert, Gallimore, Awen and Godkin, Andrew
2017.
Effect of modified vaccinia Ankara–5T4 and low-dose
cyclophosphamide on antitumor immunity in metastatic colorectal cancer
A Randomized Clinical Trial.
JAMA Oncology
3
(10)
, e172579.
10.1001/jamaoncol.2017.2579
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| Scurr, Martin J, Pembroke, Tom, Bloom, Anja, Roberts, David J, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard A, Brewster, Alison E, Jones, Robert, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Hills, Robert, Gallimore, Awen and Godkin, Andrew 2017. Low-dose cyclophosphamide induces anti-tumor T-cell responses which associate with survival in metastatic colorectal cancer. Clinical Cancer Research , clincanres.0895.2017. 10.1158/1078-0432.CCR-17-0895 |
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Scurr, Martin, Pembroke, Thomas, Bloom, Anja, roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Admas, Richard, Brewster, Alison, Jones, Robert, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa, Hills, Robert, Gallimore, Awen and Godkin, Andrew
2017.
MVA-5T4 immunotherapy (TroVax) and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): an open-label, randomized phase 1/2 clinical trial.
JAMA Oncology
Item availability restricted. |
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| Clement, Mathew, Marsden, Morgan, Stacey, Maria, Abdul-Karim, Juneid, Gimeno Brias, Silvia, Costa Bento, Diana Filipa, Scurr, Martin, Weaver, Casey, Carlesso, Gianluca, Clare, Simon, Jones, Simon, Godkin, Andrew, Ghazal, Peter, Jones, Gareth W. and Humphreys, Ian 2016. Cytomegalovirus-specific IL-10-producing CD4+ T cells are governed by type-I IFN-induced IL-27 and promote virus persistence. Plos Pathogens 12 (12) , e1006050. 10.1371/journal.ppat.1006050 |
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| Holland, C. J., Dolton, Garry Michael, Scurr, Martin John, Ladell, Kristin Ingrid, Schauenburg, Andrea J. A., Miners, Kelly Louise, Madura, F., Sewell, Andrew K., Price, David, Cole, David and Godkin, Andrew James 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. The Journal of Immunology 195 (12) , pp. 5827-5836. 10.4049/jimmunol.1402787 |
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| Scurr, Martin John, Brown, Clare M., Costa Bento, Diana Filipa, Betts, G., Rees, B. I., Hills, Robert Kerrin, Gallimore, Awen Myfanwy and Godkin, Andrew James 2015. Assessing the prognostic value of preoperative carcinoembryonic antigen-specific T-cell responses in colorectal cancer. JNCI Journal of the National Cancer Institute 107 (4) , djv001. 10.1093/jnci/djv001 |
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| Scurr, Martin, Bloom, Anja, Pembroke, Thomas, Srinivasan, R., Brown, Clare, Smart, Kathryn, Bridgeman, H., Davies, Michael, Hargest, Rachel, Phillips, Simon, Christian, Adam, Hockey, T., Gallimore, Awen and Godkin, Andrew 2013. Escalating regulation of 5T4-specific IFN- + CD4+ T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy. Cancer Immunology Research 1 (6) , 416. 10.1158/2326-6066.CIR-13-0035 |
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| Scurr, Martin John, Ladell, Kristin Ingrid, Besneux, Matthieu, Christian, Adam, Hockey, T., Smart, Kathryn, Bridgeman, Hayley, Hargest, Rachel, Phillips, S., Davies, M., Price, David, Gallimore, Awen Myfanwy and Godkin, Andrew James 2013. Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3- T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells. Mucosal Immunology n/a 10.1038/mi.2013.62 |
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| Davies, Luke Cynlais, Rosas, Marcela, Jenkins, Stephen J., Liao, Chia-Te, Scurr, Martin John, Brombacher, Frank, Fraser, Donald James, Allen, Judith E., Jones, Simon Arnett and Taylor, Philip Russel 2013. Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation. Nature Communications 4 , 1886. 10.1038/ncomms2877 |
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Scurr, Martin John
2013.
Elucidating the impact of CD4+ T cells
on tumour progression in patients
with colorectal cancer.
PhD Thesis,
Cardiff University.
Item availability restricted. |
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| Scurr, Martin John, Gallimore, Awen Myfanwy and Godkin, Andrew James 2012. T cell subsets and colorectal cancer: discerning the good from the bad. Cellular Immunology 279 (1) , pp. 21-24. 10.1016/j.cellimm.2012.08.004 |
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| Betts, Gareth James, Jones, Emma, Junaid, Syed, El-Shanawany, Tariq, Scurr, Martin John, Mizen, Paul Edward, Kumar, Mayur, Jones, Sion, Rees, Brian Idris, Williams, Geraint Trefor, Gallimore, Awen Myfanwy and Godkin, Andrew James 2012. Suppression of tumour-specific CD4+ T cells by regulatory T cells is associated with progression of human colorectal cancer. Gut 61 (8) , pp. 1163-1171. 10.1136/gutjnl-2011-300970 |
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| Clark, Stephen Robert, Guy, Christopher J., Scurr, Martin J., Taylor, Philip Russel, Kift-Morgan, Ann Patricia, Hammond, Victoria Jayne, Thomas, Christopher P., Coles, Barbara, Roberts, Gareth Wyn, Eberl, Matthias, Jones, Simon Arnett, Topley, Nicholas, Kotecha, Sailesh and O'Donnell, Valerie Bridget 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117 (6) , pp. 2033-2043. 10.1182/blood-2010-04-278887 |
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