![]() | Up a level |
Rosas, Marcela, Slatter, David A., Obaji, Samya G., Webber, Jason P., Alvarez-Jarreta, Jorge, Thomas, Christopher P., Aldrovandi, Maceler, Tyrrell, Victoria J., Jenkins, Peter V., O'Donnell, Valerie B. and Collins, Peter W.
2020.
The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles.
PLoS ONE
15
(10)
, e0240189.
10.1371/journal.pone.0240189
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King, Helen, Cosslett, Allan G., Thomas, Christopher P. and Price-Davies, Rebecca 2018. A HPLC method to monitor the occurrence of lipid peroxidation in intravenous lipid emulsions used in parenteral nutrition using in-line UV and charged aerosol detection. Clinical Nutrition ESPEN 28 , pp. 96-102. 10.1016/j.clnesp.2018.09.005 |
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Lauder, Sarah N., Allen-Redpath, Keith, Slatter, David A., Aldrovandi, Maceler, O'Connor, Anne, Farewell, Daniel, Percy, Charles L., Molhoek, Jessica E., Rannikko, Sirpa, Tyrrell, Victoria J., Ferla, Salvatore, Milne, Ginger L., Poole, Alastair W., Thomas, Christopher P., Obaji, Samya, Taylor, Philip R., Jones, Simon A., deGroot, Philip G., Urbanus, Rolf T., Horkko, Sohvi, Uderhardt, Stefan, Ackermann, Jochen, Jenkins, P. Vince, Brancale, Andrea, Kronke, Gerhard, Collins, Peter W. and O'Donnell, Valerie B.
2017.
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.
Science Signaling
10
(507)
, eaan2787.
10.1126/scisignal.aan2787
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Chiba, Takahito, Thomas, Christopher P., Calcutt, M. Wade, Boeglin, William E., O'Donnell, Valerie B. and Brash, Alan R.
2016.
The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate.
Journal of Biological Chemistry
291
(28)
, pp. 14540-14544.
10.1074/jbc.M115.711267
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Hinz, Christine, Aldrovandi, Maceler, Uhlson, Charis, Marnett, Lawrence J., Longhurst, Hilary J., Warner, Timothy D., Alam, Saydul, Slatter, David A., Lauder, Sarah N., Allen-Redpath, Keith, Collins, Peter W., Thomas, Christopher P. and O'Donnell, Valerie B.
2016.
Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid.
Journal of Biological Chemistry
291
(26)
, pp. 13448-13464.
10.1074/jbc.M115.700609
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McCully, Michelle L., Collins, Paul J., Hughes, Timothy R., Thomas, Christopher P., Billen, Jaak, O'Donnell, Valerie B. and Moser, Bernhard
2015.
Skin metabolites define a new paradigm in the localization of skin tropic memory T cells.
Journal of Immunology
195
(1)
, pp. 96-104.
10.4049/jimmunol.1402961
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Morgan, Alwena H., Hammond, Victoria J., Sakoh-Nakatogawa, Machiko, Ohsumi, Yoshinori, Thomas, Christopher P., Blanchet, Fabien, Piguet, Vincent, Kiselyov, Kirill and O'Donnell, Valerie Bridget 2015. A novel role for 12/15-lipoxygenase in regulating autophagy. Redox Biology 4 , pp. 40-47. 10.1016/j.redox.2014.11.005 |
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Muñoz-Garcia, Agustí, Thomas, Christopher P., Keeney, Diane S., Zheng, Yuxiang and Brash, Alan R. 2014. The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841 (3) , pp. 401-408. 10.1016/j.bbalip.2013.08.020 |
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Thomas, Christopher P., Clark, Stephen Robert, Hammond, Victoria Jayne, Aldrovandi, Maceler, Collins, Peter William and O'Donnell, Valerie Bridget 2014. Identification and quantification of aminophospholipid molecular species on the surface of apoptotic and activated cells. Nature Protocols 9 (1) , pp. 51-63. 10.1038/nprot.2013.163 |
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Clark, Stephen Robert, Thomas, Christopher P., Hammond, Victoria Jayne, Aldrovandi, Maceler, Wilkinson, Gavin William Grahame, Hart, Keith William, Murphy, Robert C., Collins, Peter William and O'Donnell, Valerie Bridget 2013. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proceedings of the National Academy of Sciences of the United States of America 110 (15) , pp. 5875-5880. 10.1073/pnas.1222419110 |
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Thomas, Christopher P., Boeglin, William E., Garcia-Diaz, Yoel, O'Donnell, Valerie B. and Brash, Alan R. 2013. Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. Chemistry and Physics of Lipids 167 , pp. 21-32. 10.1016/j.chemphyslip.2013.01.002 |
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Hammond, Victoria Jayne, Morgan, Alwena H., Lauder, Sarah Nicol, Thomas, Christopher P., Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J. and O'Donnell, Valerie Bridget 2012. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ. Journal of Biological Chemistry 287 (50) , pp. 41651-41666. 10.1074/jbc.M112.405407 |
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Thomas, Christopher P. and O'Donnell, Valerie Bridget 2012. Oxidized phospholipid signaling in immune cells. Current Opinion in Pharmacology 12 (4) , pp. 471-477. 10.1016/j.coph.2012.02.013 |
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Ruge, Fiona, Glavini, Aikaterini, Gallimore, Awen Myfanwy, Richards, Hannah E., Thomas, Christopher P., O'Donnell, Valerie Bridget, Philpott, Michael P. and Porter, Rebecca 2011. Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated. Journal of Investigative Dermatology 131 (3) , pp. 572-579. 10.1038/jid.2010.379 |
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Zulfakar, Mohd Hanif, Alex, Aneesh, Povazay, Boris, Drexler, Wolfgang, Thomas, Christopher P., Porter, Rebecca M. and Heard, Charles Martin 2011. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining. Experimental Dermatology 20 (3) , pp. 269-272. 10.1111/j.1600-0625.2010.01233.x |
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Trostchansky, A., Bonilla, L., Thomas, Christopher P., O'Donnell, Valerie Bridget, Marnett, L. J., Radi, R. and Rubbo, H. 2011. Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2. Journal of Biological Chemistry 286 (15) , pp. 12891-12900. 10.1074/jbc.M110.154518 |
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Clark, Stephen Robert, Guy, Christopher J., Scurr, Martin J., Taylor, Philip Russel, Kift-Morgan, Ann Patricia, Hammond, Victoria Jayne, Thomas, Christopher P., Coles, Barbara, Roberts, Gareth Wyn, Eberl, Matthias, Jones, Simon Arnett, Topley, Nicholas, Kotecha, Sailesh and O'Donnell, Valerie Bridget 2011. Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. Blood 117 (6) , pp. 2033-2043. 10.1182/blood-2010-04-278887 |
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Thomas, Christopher P., Morgan, Lloyd T., Maskrey, Ben, Murphy, Robert C., Kuhn, Hartmut, Hazen, Stanley L., Goodall, Alison H., Hamali, Hassan A., Collins, Peter William and O'Donnell, Valerie Bridget 2010. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. Journal of Biological Chemistry 285 (10) , pp. 6891-6903. 10.1074/jbc.M109.078428 |
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Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P., Tallman, Keri A., Garcia-Diaz, Yoel Ruslan, McGuigan, Christopher, Serpi, Michaela, Porter, Ned A., Murphy, Robert C. and O'Donnell, Valerie Bridget 2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5 (12) , pp. 1919-1931. 10.1038/nprot.2010.162 |
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Morgan, Lloyd T., Thomas, Christopher P., Kühn, Hartmut and O'Donnell, Valerie Bridget 2010. Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase. Biochemical Journal 431 (1) , pp. 141-148. 10.1042/BJ20100415 |
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Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P., Clark, Stephen Robert, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel, Jones, Simon Arnett and O'Donnell, Valerie Bridget 2009. Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease. Journal of Biological Chemistry 284 (32) , pp. 21185-21191. 10.1074/jbc.M109.021634 |
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Gregory, L. G., Causton, B., Murdoch, J. R., Mathie, S. A., O'Donnell, Valerie Bridget, Thomas, Christopher P., Priest, F. M., Quint, D. J. and Lloyd, C. M. 2009. Inhaled house dust mite induces pulmonary T helper 2 cytokine production. Clinical and Experimental Allergy 39 (10) , pp. 1597-1610. 10.1111/j.1365-2222.2009.03302.x |
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Heard, Charles Martin and Thomas, Christopher P. 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67 (1) , pp. 156-165. 10.1016/j.ejpb.2006.11.024 |
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Thomas, Christopher P., Davison, Zoe and Heard, Christopher Martin 2007. Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX. Prostaglandins Leukotrienes & Essential Fatty Acids 76 (6) , pp. 357-362. 10.1016/j.plefa.2007.05.002 |
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Thomas, Christopher P. and Heard, Christopher Martin 2007. Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid. European Journal of Pharmaceutics and Biopharmaceutics 67 (1) , pp. 156-165. 10.1016/j.ejpb.2006.11.024 |
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Thomas, Christopher P., Platts, James Alexis, Tatchell, Thomas and Heard, Christopher Martin 2007. Probing the skin permeation of fish oil/EPA and ketoprofen 1. NMR spectroscopy and molecular modelling. International Journal of Pharmaceutics 338 (1-2) , pp. 207-212. 10.1016/j.ijpharm.2007.02.006 |
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Heard, Charles M., Kung, Denise and Thomas, Christopher P. 2006. Skin penetration enhancement of mefenamic acid by ethanol and 1,8-cineole can be explained by the ‘pull’ effect. International Journal of Pharmaceutics 321 (1-2) , pp. 167-170. 10.1016/j.ijpharm.2006.05.018 |
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Thomas, Christopher P. 2006. Transcutaneous delivery of anti-arthritic agents. PhD Thesis, Cardiff University. |
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Heard, Charles Martin, Johnson, Sarah, Moss, Gary and Thomas, Christopher P. 2006. In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana. International Journal of Pharmaceutics 317 (1) , pp. 26-31. 10.1016/j.ijpharm.2006.02.042 |
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Richards, Helen, Thomas, Christopher P., Bowen, Jenna L. and Heard, Charles Martin 2006. In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil. African Journal of Pharmacy and Pharmacology 58 (7) , pp. 903-908. 10.1211/jpp.58.7.0004 |
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Heard, Charles Martin, Gallagher, Simon John, Congiatu, Costantino, Harwood, John L., Thomas, Christopher P., McGuigan, Christopher, Nemcova, Marta and Nouskova, Tereza 2005. Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation. International Journal of Pharmaceutics 302 (1-2) , pp. 47-55. 10.1016/j.ijpharm.2005.06.013 |
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Ho, Suzanna, Calder, Richard J., Thomas, Christopher P. and Heard, Charles Martin 2004. In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole. Pharmacy and Pharmacology 56 (11) , pp. 1357-1364. 10.1211/0022357044599 |
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Batchelder, R. J., Calder, R. J., Thomas, Christopher P. and Heard, Charles Martin 2004. In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis. International Journal of Pharmaceutics 283 (1-2) , pp. 45-51. 10.1016/j.ijpharm.2004.06.007 |
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Davidge, Janette, Thomas, Christopher P. and Williams, David R. 2001. Conditional formation constants or chemical speciation data? Chemical Speciation and Bioavailability 13 (4) , pp. 129-134. 10.3184/095422901782775390 |
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