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Number of items: 79.

Watson, H. Angharad, Dolton, Garry Michael, Ohme, Julia, Ladell, Kristin Ingrid, Vigar, Miriam, Wehenkel, Sophie, Hindley, James, Mohammed, Rebar, Miners, Kelly, Luckwell, Rhys A, Price, David, Matthews, R James and Ager, Ann 2016. Purity of transferred CD8+ T cells is crucial for safety and efficacy of combinatorial tumor immunotherapy in the absence of SHP-1. Immunology and Cell Biology 94 , pp. 802-808. 10.1038/icb.2016.45
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Watson, Heulwen Angharad, Wehenkel, Sophie, Matthews, James and Ager, Elizabeth 2016. SHP-1: the next checkpoint target for cancer immunotherapy? Biochemical Society Transactions 44 (2) , pp. 356-362. 10.1042/BST20150251
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Ager, Elizabeth, Watson, Heulwen Angharad, Wehenkel, Sophie C. and Mohammed, Rebar N. 2016. Homing to solid cancers: a vascular checkpoint in adoptive cell therapy using CAR T-cells. Biochemical Society Transactions 44 (2) , pp. 377-385. 10.1042/BST20150254
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Mohammed, Rebar N., Watson, Heulwen Angharad, Vigar, Miriam, Ohme, Julia, Thomson, Amanda, Humphreys, Ian R. and Ager, Ann 2016. L-selectin is essential for delivery of activated CD8+ T cells to virus-infected organs for protective immunity. Cell Reports 14 (4) , pp. 760-771. 10.1016/j.celrep.2015.12.090
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Ager, Ann and May, Michael J. 2015. Understanding high endothelial venules: Lessons for cancer immunology. OncoImmunology 4 (6) , e1008791. 10.1080/2162402X.2015.1008791
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Ager, Ann and May, Michael J. 2015. Understanding high endothelial venules: lessons for cancer immunology. OncoImmunology 4 (6) , e1008791. 10.1080/2162402X.2015.1008791
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Ondondo, Beatrice, Colbeck, Emily, Jones, Emma, Smart, Kathryn, Lauder, Sarah Nicol, Hindley, James Philip, Godkin, Andrew James, Moser, Bernhard, Ager, Ann and Gallimore, Awen Myfanwy 2015. A distinct chemokine axis does not account for enrichment of Foxp3+ CD4+T cells in carcinogen-induced fibrosarcomas. Immunology 145 (1) , pp. 94-104. 10.1111/imm.12430
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Costa Bento, Diana Filipa, Jones, Emma, Junaid, Syed, Tull, Justyna, Williams, Geraint Trefor, Godkin, Andrew James, Ager, Ann and Gallimore, Awen Myfanwy 2015. High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression. OncoImmunology 4 (3) , e974374. 10.4161/2162402X.2014.974374
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Ondondo, Beatrice, Jones, Emma, Hindley, James, Cutting, Scott, Smart, Kathryn, Bridgeman, Hayley, Matthews, Katherine K., Ladell, Kristin Ingrid, Price, David, Jackson, David G., Godkin, Andrew James, Ager, Ann and Gallimore, Awen Myfanwy 2014. Progression of carcinogen-induced fibrosarcomas is associated with the accumulation of naïve CD4+ T cellsviablood vessels and lymphatics. International Journal of Cancer 134 (9) , pp. 2156-2167. 10.1002/ijc.28556
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Humphreys, Ian R., Clement, Mathew, Marsden, Morgan, Ladell, Kristin Ingrid, McLaren, James Edward, Smart, Kathryn, Hindley, James Philip, Bridgeman, Hayley, van den Berg, Hugo A., Price, David, Ager, Ann, Wooldridge, Linda, Godkin, Andrew James and Gallimore, Awen Myfanwy 2012. Avidity of influenza-specific memory CD8+T-cell populations decays over time compromising antiviral immunity. European Journal of Immunology 42 (12) , pp. 3235-3242. 10.1002/eji.201242575

Hindley, James Phillip, Jones, Emma, Smart, Kathryn, Bridgeman, Hayley, Lauder, Sarah Nicol, Ondondo, Beatrice Omusiro, Cutting, Scott, Ladell, Kristin Ingrid, Wynn, Katherine Kay, Withers, David, Price, David, Ager, Ann, Godkin, Andrew James and Gallimore, Awen Myfanwy 2012. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T cell depletion. Cancer Research 72 (21) , pp. 5473-5482. 10.1158/0008-5472.CAN-12-1912

Klinger, A., Gebert, A., Bieber, K., Kalies, K., Ager, Ann, Bell, E. B. and Westermann, J. 2009. Cyclical expression of L-selectin (CD62L) by recirculating T cells. International Immunology 21 (4) , pp. 443-455. 10.1093/intimm/dxp012

Anderson, Britt E., Taylor, Patricia A., McNiff, Jennifer M., Jain, Dhanpat, Demetris, Anthony J., Panoskaltsis-Mortari, Angela, Ager, Ann, Blazar, Bruce R., Shlomchik, Warren D. and Shlomchik, Mark J. 2008. Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells. Blood 111 (10) , pp. 5242-5251. 10.1182/blood-2007-09-107953

Sinclair, Linda V., Finlay, David, Feijoo, Carmen, Cornish, Georgina H., Gray, Alex, Ager, Ann, Okkenhaug, Klaus, Hagenbeek, Thijs J., Spits, Hergen and Cantrell, Doreen A. 2008. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nature Immunology 9 (5) , pp. 513-521. 10.1038/ni.1603

Richards, Hannah Catharine, Longhi, Maria Paula, Wright, Kate Louise, Gallimore, Awen Myfanwy and Ager, Ann 2008. CD62L (L-Selectin) down-regulation does not affect memory T cell distribution but failure to shed compromises anti-viral immunity. Journal of Immunology 180 (1) , pp. 198-206.

Sinclair, Linda V., Finlay, David, Feijoo, Carmen, Cornish, Georgina H., Gray, Alex, Ager, Ann, Okkenhaug, Klaus, Hagenbeek, Thijs J., Spits, Hergen and Cantrell, Doreen A. 2008. Corrigendum: phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nature Immunology 9 (6) , p. 692. 10.1038/ni0608-692

Anderson, Britt E., Zheng, Hong, Taylor, Patricia A., Matte-Martone, Catherine, McNiff, Jennifer M., Jain, Dhanpat, Demetris, Anthony J., Panoskaltsis-Mortari, Angela, Ager, Ann, Blazar, Bruce R., Shlomchik, Mark J. and Shlomchik, Warren D. 2008. Memory T Cells in GVHD and GVL. Biology of Blood and Marrow Transplantation 14 (Supp.1) , pp. 19-20. 10.1016/j.bbmt.2007.10.013

Ager, Ann, Galkina, Elena, Preece, Graham and Lawrence, Michael B 2007. T lymphocyte rolling and recruitment into peripheral lymph nodes is regulated by a saturable density of L-selectin (CD62L). European Journal of Immunology 37 (5) , pp. 1243-1253. 10.1002/eji.200636481

Ivetic, Aleksander, Florey, Oliver, Deka, Jurgen, Haskard, Dorian O., Ager, Ann and Ridley, Anne J. 2004. Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering. Journal of Biological Chemistry 279 (32) , pp. 33263-33272. 10.1074/jbc.M312212200

Ager, Ann, Kioussis, D., Haskard, D. O. and Galkina, E. 2003. L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. Journal of Experimental Medicine 198 (9) , pp. 1323-1335. 10.1084/jem.20030485
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Ager, Ann 2003. Inflammation: border crossings. Nature 421 (6924) , pp. 703-705. 10.1038/421703a

Ager, Ann, Ivetic, A., Ridley, A. and Deka, J. 2002. The cytoplasmic tail of L-selectin interacts with members of the Ezrin-Radixin-Moesin (ERM) family of proteins: cell activation-dependent binding of Moesin but not Ezrin. Journal of Biological Chemistry 277 (3) , pp. 2321-2329. 10.1074/jbc.M109460200

Phillips, Rhian and Ager, Ann 2002. Activation of pertussis toxin-sensitive CXCL12 (SDF-1) receptors mediates transendothelial migration of T lymphocytes across lymph node high endothelial cells. European Journal of Immunology 32 (3) , pp. 837-847. 10.1002/1521-4141(200203)32:3<837::AID-IMMU837>3.0.CO;2-Q

Ager, Ann, Faveeuw, Christelle and Preece, Graham 2001. Transendothelial migration of lymphocytes across high endothelial venules into lymph nodes is affected by metalloproteinases. Blood 98 (3) , pp. 688-95. 10.1182/blood.V98.3.688

Ivetic, Aleksander, Deka, Jurgen, Ridley, Anne and Ager, Ann 2001. The cytoplasmic tail of L-selectin interacts with members of the ezrin-radixin-moesin (ERM) family of proteins: activation-dependent binding of moesin but not ezrin. Journal of Biological Chemistry 277 (3) , pp. 2321-2329. 10.1074/jbc.M109460200

Faveeuw, Christelle, Di Mauro, Mary E., Price, Abigail A. and Ager, Ann 2000. Roles of alpha4 integrins/VCAM-1 and LFA-1/ICAM-1 in the binding and transendothelial migration of T lymphocytes and T lymphoblasts across high endothelial venules. International Immunology 12 (3) , pp. 241-251. 10.1093/intimm/12.3.241

Derry, Catherine J., Faveeuw, Christelle, Mordsley, Kelly R. and Ager, Ann 1999. Novel chondroitin sulfate-modified ligands for L-selectin on lymph node high endothelial venules. European Journal of Immunology 29 (2) , pp. 419-430. 10.1002/(SICI)1521-4141(199902)29:02<419::AID-IMMU419>3.0.CO;2-A

Borland, Gillian, Murphy, Gillian and Ager, Ann 1999. Tissue inhibitor of metalloproteinases-3 inhibits shedding of L-selectin from leukocytes. Journal of Biological Chemistry 274 (5) , pp. 2810-2815. 10.1074/jbc.274.5.2810

Price, Abigail A., Cumberbatch, Marie, Kimber, Ian and Ager, Ann 1997. α6 integrins are required for Langerhans cell migration from the epidermis. Journal of Experimental Medicine 186 (10) , pp. 1725-1735. 10.1084/jem.186.10.1725
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Middelhoven, P. J., Ager, Ann, Roos, D. and Verhoeven, A. J. 1997. Involvement of a metalloprotease in the shedding of human neutrophil FcγRIIIB. FEBS Letters 414 (1) , pp. 14-18. 10.1016/S0014-5793(97)00959-9

Faveeuw, Christelle, Di Mauro, Mary and Ager, Ann 1997. Adhesion molecules used by T lymphoblasts to interact with cultured high endothelial cells [Abstract]. Biochemical Society Transactions 25 (2) , 261S.

Allport, J. R., Ding, H. T., Ager, Ann, Steeber, D. A., Tedder, T. F. and Luscinskas, F. W. 1997. L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro. Journal of Immunology 158 (9) , pp. 4365-4372.

Derry, Catherine J., Mordsley, Kelly R., Preece, Graham and Ager, Ann 1997. Purification of L-selectin ligands synthesised by rat peripheral lymph nodes and cultured high endothelial cells [Abstract]. Biochemical Society Transactions 25 (2) , 260S.

del Pozo, Miguel Angel, Cabañas, Carlos, Montoya, Maria C., Ager, Ann, Sánchez-Mateos, Paloma and Sánchez-Madrid, Francisco 1997. ICAMs redistributed by chemokines to cellular uropods as a mechanism for recruitment of T lymphocytes. Journal of Cell Biology 137 (2) , pp. 493-508. 10.1083/jcb.137.2.493
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Preece, Graham, Murphy, Gillian and Ager, Ann 1996. Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. Journal of Biological Chemistry 271 (20) , pp. 11634-11640. 10.1074/jbc.271.20.11634

Allport, J. R., Ding, H., Ager, Ann and Luscinskas, F. W. 1996. Inhibition of L-selectin shedding does not affect human neutrophil attachment, rolling or transendothelial migration. Molecular Biology of the Cell 7 , p. 3502.

ParraRuiz, S. and Ager, Ann 1996. Regulation of of integrins on rat lymphocytes [Abstract]. Immunology 89 (Supp1) , p. 59.

Ager, Ann and Preece, G. 1996. The regulation of lymphocyte migration across high endothelial venules [Abstract]. Immunology 89 (Supp1) , ST77.

Middelhoven, P. J., Ager, Ann, Roos, D. and Verhoeven, A. J. 1996. Possible role of a metalloprotease in the shedding of neutrophil Fc gamma IIIb [Abstract]. Journal of Leukocyte Biology Supp S , p. 169.

Middelhoven, H., Ager, Ann, Roos, D. and Verhoeven, A. J. 1996. Possible role of metalloprotease in the shedding of neutrophil Fc gamma RIIIb [Abstract]. Journal of Leukocyte Biology Supp S , p. 174.

Bell, Eric B., Sparshott, Sheila M. and Ager, Ann 1995. Migration pathways of CD4 T cell subsets in vivo: the CD45RC- subset enters the thymus via α4 integrin-VCAM-1 interaction. International Immunology 7 (11) , pp. 1861-1871. 10.1093/intimm/7.11.1861

Price, A. A., Kimber, I. and Ager, Ann 1995. The expression of VLA-4 and VLA-6 by langerhans cells - their potential role in regulating langerhans cell-migration[Abstract]. Journal of Investigative Dermatology 105 (6) , pp. 858-869. 10.1111/1523-1747.ep12326705

Ager, Ann 1994. Lymphocyte recirculation and homing: roles of adhesion molecules and chemoattractants. Trends in Cell Biology 4 (9) , pp. 326-332. 10.1016/0962-8924(94)90234-8

Ager, Ann, Preece, G. and Wood, A. C. 1994. Down-regulation of lymphocyte L-selectin on binding to high endothelium - a prerequisite for transmigration [Abstract]. Journal of Cellular Biochemistry 56 (S18A) , p. 331.

Bird, I. N., Spragg, J. H., Ager, Ann and Matthews, N. 1993. Studies of lymphocyte transendothelial migration: analysis of migrated cell phenotypes with regard to CD31 (PECAM-1), CD45RA and CD45RO. Immunology 80 (4) , pp. 553-560.

Edwards, Brian D., Slevin, Mark A., Dickson, Alan J., Ager, Ann and Ballardie, Francis W. 1993. Antiproliferative actions of cyclosporin A on endothelial cells are not exerted through protein kinase C (PkC) [Abstract]. Biochemical Society Transactions 21 (4) , 423S. 10.1042/bst021423s

Edwards, Brian D., Slevin, Mark A., Dickson, Alan J., Ager, Ann and Ballardie, W. 1993. Calphostin C inhibits endothelial cell proliferation and selectively modulates cell-surface marker expression [Abstract]. Biochemical Society Transactions 21 (4) , 422S. 10.1042/bst021422s

Ager, Ann 1993. Lymphocyte-vascular endothelial cell interactions in the immune response. Clinical and experimental immunology 93 (Supp 1) , pp. 5-6. 10.1111/j.1365-2249.1993.tb06213.x

May, M. J., Entwistle, G., Humphries, M. J. and Ager, Ann 1993. VCAM-1 is a CS1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium. Journal of Cell Science (JCS) 106 (1) , pp. 109-119.

Ensari, A., Ager, Ann, Marsh, M. N., Morgan, S. and Moriarty, K. J. 1993. Time-course of adhesion molecule expression in rectal mucosa of gluten-sensitive subjects after gluten challenge. Clinical and experimental immunology 92 (2) , pp. 303-307. 10.1111/j.1365-2249.1993.tb03396.x

Hourihan, H., Allen, T. D. and Ager, Ann 1993. Lymphocyte migration across high endothelium is associated with increases in alpha 4 beta 1 integrin (VLA-4) affinity. Journal of Cell Science (JCS) 104 (4) , pp. 1049-9.

Szekanecz, Z., Humphries, M. J. and Ager, Ann 1992. Lymphocyte adhesion to high endothelium is mediated by two beta 1 integrin receptors for fibronectin, alpha 4 beta 1 and alpha 5 beta 1. Journal of Cell Science (JCS) 101 (4) , pp. 885-894.

Bradley, J. Andrew, Sarawar, Sally R., Porteous, Colin, Wood, Peter J., Card, Sharon, Ager, Ann, Bolton, Eleanor M. and Bell, Eric B. 1992. Allograft rejection in Cd4+ T cell-reconstituted athymic nude rats-the nonessential role of host-derived Cd8+ cells1. Transplantation 53 (2) , pp. 477-482.

Ensari, A., Marsh, M. N., Ager, Ann, Morgan, S. and Moriarty, K. J. 1992. Expression of adhesion molecules in glutenchallenged, coeliac disease (CD) rectal mucosa. Gut 33 (Supp 2) , S67.

May, Michael J. and Ager, Ann 1992. ICAM-1-independent lymphocyte transmigration across high endothelium: differential up-regulation by interferon γ, tumor necrosis factor-α and interleukin 1β. European Journal of Immunology 22 (1) , pp. 219-226. 10.1002/eji.1830220132

Vaage, John Torgils, Dissen, Erik, Ager, Ann, Fossum, Sigbjørn and Rolstad, Bent 1991. Allospecific recognition of hemic cells in vitro by natural killer cells from athymic rats: evidence that allodeterminants coded for by single major histocompatibility complex haplotypes are recognized. European Journal of Immunology 21 (9) , pp. 2167-2175. 10.1002/eji.1830210927

Ager, Ann and Humphries, Martin J. 1991. Integrin alpha 4 beta 1: its structure, ligand-binding specificity and role in lymphocyte-endothelial cell interactions. Chemical Immunology 50 , pp. 55-74.

Vaage, John Torgils, Dissen, Erik, Ager, Ann, Roberts, Ian, Fossum, Sigbjørn and Rolstad, Bent 1990. T cell receptor-bearing cells among rat intestinal intraepithelial lymphocytes are mainly α/β+ and are thymus dependent. European Journal of Immunology 20 (5) , pp. 1193-1196. 10.1002/eji.1830200538

Ager, Ann and Humphries, Martin J. 1990. Use of synthetic peptides to probe lymphocyte – high endothelial cell interactions. Lymphocytes recognize a ligand on the endothelial surface which contains the CS1 adhesion motif. International Immunology 2 (10) , pp. 921-928. 10.1093/intimm/2.10.921

Ager, Ann and Mistry, Shilaben 1988. Correction: Interaction between lymphocytes and cultured high endothelial cells: an in vitro model of lymphocyte migration across high endothelial venule endothelium. European Journal of Immunology 18 (11) , p. 1871. 10.1002/eji.1830181137

Ager, Ann, Fajumi, James, Sparshott, Sheila M., Ford, William L. and Butcher, Geoffrey W. 1988. Major histocompatibility complex control of nk-related allogeneic lymphocyte cytotoxicity in rats the contributions of strong and medial transplantation antigens. Transplantation 46 (5) , pp. 762-767.

Ager, Ann and Mistry, Shilaben 1988. Interaction between lymphocytes and cultured high endothelial cells: an in vitro model of lymphocyte migration across high endothelial venule endothelium. European Journal of Immunology 18 (8) , pp. 1265-1274. 10.1002/eji.1830180818

Ager, Ann and Mistry, Shilaben 1988. The expression of lymphocyte adhesion molecules on cultured high endothelial cells. Advances in Experimental Medicine and Biology 237 , pp. 471-476.

Ager, Ann 1987. Isolation and culture of high endothelial cells from rat lymph nodes. Journal of Cell Science (JCS) 87 (1) , pp. 133-144.

Kumar, Shant, West, David C. and Ager, Ann 1987. Heterogeneity in endothelial cells from large vessels and microvessels. Differentiation 36 (1) , pp. 57-70. 10.1111/j.1432-0436.1987.tb00181.x

Fossum, Sigbjørn, Ager, Ann and Rolstad, B. 1987. Specific inhibition of natural killer (NK) activity against different alloantigens. Immunogenetics 26 (6) , pp. 329-338. 10.1007/BF00343700

Felce, David John, Dekock, U., Thomas, M., Repp, A., Ager, Ann and Blunden, R. 1985. Staff-client ratios and their effects on staff interactions and client behaviors [Abstract]. Bulletin of the British Psychological Society 38 , A61.

Ager, Ann and Gordon, J. L. 1984. Cellular effects of proteinase activity in commercial xanthine oxidase [Letter]. Biochemical Journal 222 (3) , p. 839.

LeRoy, E. C., Ager, Ann and Gordon, J. L. 1984. Effects of neutrophil elastase and other proteases on porcine aortic endothelial prostaglandin I2 production, adenine nucleotide release, and responses to vasoactive agents. The Journal of Clinical Investigation 74 (3) , pp. 1003-1010. 10.1172/JCI111467
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Ager, Ann, Wenham, D. J. and Gordon, J. L. 1984. Stimulation of endothelial cells by protease activity in commercial preparations of xanthine oxidase. Thrombosis Research 35 (1) , pp. 43-52. 10.1016/0049-3848(84)90311-6

Ager, Ann and Gordon, J. L. 1984. Differential effects of hydrogen peroxide on indices of endothelial cell function. Journal of Experimental Medicine 159 (2) , pp. 592-603. 10.1084/jem.159.2.592
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Ager, Ann and Martin, W. 1983. Loss of receptor-mediated 86Rb efflux from pig aortic endothelial cells in culture. British Journal of Pharmacology 80 (1) , pp. 5-6. 10.1111/j.1476-5381.1983.tb11040.x

Chesterman, Colin N., Ager, Ann and Gordon, J. L. 1983. Regulation of prostaglandin production and ectoenzyme activities in cultured aortic endothelial cells. Journal of Cellular Physiology 116 (1) , pp. 45-50. 10.1002/jcp.1041160108

Ager, Ann, Gordon, John L., Moncada, Salvador, Pearson, Jeremy D., Salmon, John A. and Trevethick, Michael A. 1982. Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells. Journal of Cellular Physiology 110 (1) , pp. 9-16. 10.1002/jcp.1041100103

Ager, Ann 1982. Effects of xanthine: xanthine oxidase on membrane function: an in vitro model of endothelial damage. Agents and Actions Supplements 11 , pp. 73-81.

Ager, Ann and Gordon, John L. 1981. Influence of human β-thromboglobulin on prostaglandin production by pig aortic endothelial cells in culture. Thrombosis Research 24 (1-2) , pp. 95-103. 10.1016/0049-3848(81)90035-9

Ager, Ann and Gordon, John L. 1980. Effects of vasoactive and inflammatory agents on cyclic AMP levels in W 138 fibroblasts, endothelial and vascular smooth muscle cells in culture. Agents and Actions 10 (6) , pp. 569-572.

Ager, Ann, Pearson, Jeremy D. and Gordon, John L. 1979. Radioimmunoassay of 6-oxoprostaglandin F1α and prostaglandin E2 produced by pig aortic endothelium in culture [Abstract]. Biochemical Society Transactions 7 (5) , pp. 1065-1066. 10.1042/bst0071065

Pearson, Jeremy D., Ager, Ann, Trevethick, M. A. and Gordon, John L. 1979. Prostaglandin production by cultured vascular cells. Agents and Actions Supplements 4 , pp. 120-126.

This list was generated on Sun Apr 30 07:08:24 2017 BST.