Browse by Current Cardiff authors

Samy, Abdallah M., Gallagher, Theresa B., Mellado-Sanchez, Gabriela, Jorgensen, Ana L., Moore, Stephen, Nataro, James P., Pasetti, Marcela F. and Baillie, Les W. 2019. Development of a multiple-antigen protein fusion vaccine candidate that confers protection against Bacillus anthracis and Yersinia pestis. PLoS Neglected Tropical Diseases 13 (8) , e0007644. 10.1371/journal.pntd.0007644

Hamzah, H., Ahortor, E., Malyshev, D., Choi, H., Lees, J., Baillie, L. and Porch, A. 2019. A compact microwave applicator for the rapid detection of clostridium difficile. Presented at: 2019 IEEE MTT-S International Microwave Biomedical Conference (IMBioC), Nanjing, China, 6-8 May 2019. 2019 IEEE MTT-S International Microwave Biomedical Conference (IMBioC). IEEE, 10.1109/IMBIOC.2019.8777882

Malyshev, Dmitry, Williams, Catrin F., Lees, Jonathan, Baillie, Les and Porch, Adrian 2019. Model of microwave effects on bacterial spores. Journal of Applied Physics 125 (12) , 124701. 10.1063/1.5085442

Sahin, Mitat, Buyuk, Fatih, Baillie, Les, Wölfel, Roman, Kotorashvili, Adam, Rehn, Alexandra, Antwerpen, Markus and Grass, Gregor 2018. The identification of novel single nucleotide polymorphisms to assist in mapping the spread of Bacillus anthracis across the Southern Caucasus. Scientific Reports 8 (1) , 11254. 10.1038/s41598-018-29738-3

Moore, Adam, Davies, Thomas, Berube, Kelly, Jones, Timothy and Baillie, Les 2018. Bio-reactive clay minerals and anthrax decontamination: a novel antimicrobial solution. Presented at: Focused Meeting on Emerging Zoonoses and Antimicrobial Resistance, School of Veterinary Medicine, University of Surrey, Guildford, UK, 2 July 2018.

Ingavle, Ganesh, Baillie, Les, Davies, Nathan, Beaton, Nigel, Zheng, Yishan, Mikhalovsky, Sergey and Sandeman, Susan 2018. Bioinspired detoxification of blood: The efficient removal of anthrax toxin protective antigen using an extracorporeal macroporous adsorbent device. Scientific Reports 8 (1) , 7518. 10.1038/s41598-018-25678-0

Baptista, Rafael, Bhowmick, Sumana, Nash, Robert J., Baillie, Les and Mur, Luis AJ 2018. Target discovery focused approaches to overcome bottlenecks in the exploitation of antimycobacterial natural products. Future Medicinal Chemistry 10 (7) , pp. 811-822. 10.4155/fmc-2017-0273

Baptista, Rafael, Fazakerley, David M., Beckmann, Manfred, Baillie, Les and Mur, Luis A. J. 2018. Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824). Scientific Reports 8 (1) , 5084. 10.1038/s41598-018-23110-1

Schelkle, Bettina, Choi, Young, Baillie, Les, Richter, William, Buyuk, Fatih, Celik, Elif, Wendling, Morgan, Sahin, Mitat and Gallagher, Theresa 2018. Caenorhabditis elegans predation on Bacillus anthracis: decontamination of spore contaminated soil with germinants and nematodes. Frontiers in Microbiology 8 , 2106. 10.3389/fmicb.2017.02601

Centeleghe, Isabella, Myles, Erin, Baillie, Les, Berube, Kelly, Jones, Timothy and Blaxland, James 2018. Combating the rising global threat of antimicrobial resistance with clay minerals: A study on two major hospital superbugs. Presented at: Focused meeting 2018: Emerging zoonoses and AMR: A global threat, University of Surrey, 02-02 July 2018.

Khmaladze, E, Su, W, Zghenti, E, Buyuk, F, Sahin, M, Nicolich,MP, MP, Baillie, Les, Obiso, R and Kotorashvili, A 2017. Molecular genotyping of bacillus anthracis strains from Georgia and northeastern part of Turkey. Journal of Bacteriology and Mycology 4 (3)

Joshi, Lovleen Tina, Welsch, Angelina, Hawkins, Jennifer and Baillie, Les 2017. The effect of hospital biocide sodium dichloroisocyanurate on the viability and properties of Clostridium difficile spores. Letters in Applied Microbiology 65 (3) , pp. 199-205. 10.1111/lam.12768

Cooper, Callum, Buyuk, Fatih, Schelkle, Bettina, Saglam, Aliye Gulmez, Celik, Elif, Celebi, Ozgur, Sahin, Mitat, Hawkyard, Tom and Baillie, Les 2016. Virulence plasmid stability in environmentally occurring Bacillus anthracis from North East Turkey. Antonie van Leeuwenhoek 110 (1) , pp. 167-170. 10.1007/s10482-016-0767-5

Dyer, Paul D.R., Kotha, Arun K., Gollings, Alex S., Shorter, Susan A., Shepherd, Thomas R., Pettit, Marie W., Alexander, Bruce D., Getti, Giulia T.M., El-Daher, Samer, Baillie, Les and Richardson, Simon C.W. 2016. An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin. Biochimica et Biophysica Acta (BBA) - General Subjects 1860 (7) , pp. 1541-1550. 10.1016/j.bbagen.2016.03.024

Celebi, Ozgur, Buyuk, Fatih, Pottage, Tom, Crook, Ant, Hawkey, Suzanna, Cooper, Callum, Bennett, Allan, Sahin, Mitat and Baillie, Les 2016. The use of germinants to potentiate the sensitivity of Bacillus anthracis spores to peracetic acid. Frontiers in Microbiology 7 , 18. 10.3389/fmicb.2016.00018

Eissa, Ahmed G., Blaxland, James A., Williams, Rhodri O., Metwally, Kamel A., El-Adl, Sobhy M., Lashine, El-Sayed M., Baillie, Les and Simons, Claire 2016. Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficileof novel 3-biaryl-N-benzylpropan-1-amine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6) , pp. 1694-1697. 10.3109/14756366.2016.1140754

Ascough, Stephanie, Ingram, Rebecca J., Chu, Karen K. Y., Musson, Julie A., Moore, Stephen J., Gallagher, Theresa, Baillie, Les, Williamson, Ethel D., Robinson, John H., Maillere, Bernard, Boyton, Rosemary J. and Altmann, Daniel M. 2016. CD4+ T cells targeting dominant and cryptic epitopes from Bacillus anthracis lethal factor. Frontiers in Microbiology 6 , 1506. 10.3389/fmicb.2015.01506

Dyer, Paul D.R., Shepherd, Thomas R., Gollings, Alexander S., Shorter, Susan A., Gorringe-Pattrick, Monique A.M., Tang, Chun-Kit, Cattoz, Beatrice N., Baillie, Les, Griffiths, Peter C. and Richardson, Simon C.W. 2015. Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity. Journal of Controlled Release 220 (A) , pp. 316-328. 10.1016/j.jconrel.2015.10.054

Hawkins, Jennifer, de Vere, Natasha, Griffith, Adelaida, Ford, Col R., Allainguillaume, Joel, Hegarty, Matthew J., Baillie, Les and Adams-Groom, Beverley 2015. Using DNA metabarcoding to identify the floral composition of honey: a new tool for investigating honey bee foraging preferences. PLoS ONE 10 (8) , e0134735. 10.1371/journal.pone.0134735

Buyuk, Fatih, Sahin, Mitat, Cooper, Callum, Celebi, Ozgur, Saglam, Aliye Gulmez, Baillie, Les, Celik, Elif, Akca, Dogan, Otlu, Salih and Calendar, Richard 2015. The effect of prolonged storage on the virulence of isolates of Bacillus anthracis obtained from environmental and animal sources in the Kars Region of Turkey. FEMS Microbiology Letters 362 (13) , fnv102. 10.1093/femsle/fnv102

Köhler, Susanne M., Baillie, Les and Beyer, Wolfgang 2015. BclA and toxin antigens augment each other to protect NMRI mice from lethal Bacillus anthracis challenge. Vaccine 33 (24) , pp. 2771-2777. 10.1016/j.vaccine.2015.04.049

Ingavle, Ganesh C., Baillie, Les, Zheng, Yishan, Lis, Elzbieta K., Savina, Irina N., Howell, Carol A., Mikhalovsky, Sergey V. and Sandeman, Susan R. 2015. Affinity binding of antibodies to supermacroporous cryogel adsorbents with immobilized protein A for removal of anthrax toxin protective antigen. Biomaterials 50 , pp. 140-153. 10.1016/j.biomaterials.2015.01.039

Ingram, Rebecca J., Ascough, Stephanie, Reynolds, Catherine J., Metan, Gökhan, Doganay, Mehmet, Baillie, Les, Williamson, Diane E., Robinson, John H., Maillere, Bernard, Boyton, Rosemary J. and Altmann, Daniel M. 2015. Natural cutaneous anthrax infection, but not vaccination, induces a CD4+ T cell response involving diverse cytokines. Cell & Bioscience 5 , 20. 10.1186/s13578-015-0011-4

Stedmon, Alex W., Eachus, Peter, Baillie, Les, Tallis, Huw, Donkor, Richard, Edlin-White, Robert and Bracewell, Robert 2015. Scalable interrogation: Eliciting human pheromone responses to deception in a security interview setting. Applied Ergonomics 47 , pp. 26-33. 10.1016/j.apergo.2014.08.015

Joshi, Lovleen Tina, Mali, Buddha L., Geddes, Chris D. and Baillie, Les 2014. Extraction and sensitive detection of toxins A and B from the human pathogen clostridium difficile in 40 seconds using microwave-accelerated metal-enhanced fluorescence. PLoS ONE 9 (8) , e104334. 10.1371/journal.pone.0104334

Ascough, Stephanie, Ingram, Rebecca J., Chu, Karen K., Reynolds, Catherine J., Musson, Julie A., Doganay, Mehmet, Metan, Gökhan, Ozkul, Yusuf, Baillie, Les, Sriskandan, Shiranee, Moore, Stephen J., Gallagher, Theresa B., Dyson, Hugh, Williamson, E. Diane, Robinson, John H., Maillere, Bernard, Boyton, Rosemary J. and Altmann, Daniel M. 2014. Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T Cell immunity. PLoS Pathogens 10 (5) , e1004085. 10.1371/journal.ppat.1004085

Gallagher, T. and Baillie, Les 2013. Anthrax in zoonoses. In: Palmer, S. R., Soulsby, Lord, Torgerson, P. and Brown, D. W. G. eds. Oxford Textbook of Zoonoses Biology, Clinical Practice, and Public Health Control. Second Edition, Oxford Textbooks In Public Health, Oxford University Press,

Eachus, Peter, Stedmon, Alex and Baillie, Les 2013. Hostile intent in public crowded spaces: A field study. Applied Ergonomics 44 (5) , pp. 703-709. 10.1016/j.apergo.2012.05.009

Ingram, Rebecca J., Harris, Alison, Ascough, Stephanie, Metan, Gökhan, Doganay, Mehmet, Baillie, Les, Williamson, E. Diane, Dyson, Hugh, Robinson, John H., Sriskandan, Shiranee and Altmann, Daniel M. 2013. Exposure to anthrax toxin alters human leukocyte expression of Anthrax toxin receptor 1. Clinical and Experimental Immunology 173 (1) , pp. 84-91. 10.1111/cei.12090

Baillie, Les 2013. Can one size fit all? Towards a universal anthrax vaccine [Editorial]. Future Microbiology 8 (3) , pp. 295-297. 10.2217/fmb.13.11

Williams, Gareth John, Linley, Ezra, Nicholas, Rebecca and Baillie, Les 2013. The role of the exosporium in the environmental distribution of anthrax. Journal of Applied Microbiology 114 (2) , pp. 396-403. 10.1111/jam.12034

Zhang, J., Jex, E., Feng, T., Sivko, G. S., Baillie, Les, Goldman, S., Van Kampen, K. R. and Tang, D.-C. C. 2013. An adenovirus-vectored nasal vaccine confers rapid and sustained protection against Anthrax in a single-dose regimen. Clinical and Vaccine Immunology 20 (1) , pp. 1-8. 10.1128/CVI.00280-12

Baillie, Les and Theriault, S. 2013. The control of biological agents. In: Fraise, A. P., Maillard, Jean-Yves and Satar, S. eds. Principles and Practice of Disinfection, Preservation and Sterilization, Wiley-Blackwell, p. 576.

Joshi, Lovleen Tina, Phillips, Daniel S., Williams, Catrin Ffion, Alyousef, Abdullah and Baillie, Les 2012. Contribution of Spores to the Ability of Clostridium difficile To Adhere to Surfaces. Applied and Environmental Microbiology 78 (21) , pp. 7671-7679. 10.1128/AEM.01862-12

Ascough, S., Ingram, R. J., Musson, J. A., Doganay, M., Baillie, Les, Williamson, E. D., Robinson, J. H., Maillere, B., Sriskandan, S. and Altmann, D. M. 2012. Identification of immunodominant T cell epitopes from anthrax protective antigen for inclusion in a rationally designed sub-unit based vaccine [Abstract]. Immunology 137 (S1) , p. 761. 10.1111/imm.12002

Albrecht, M. T., Eyles, J. E., Baillie, Les and Keane-Myers, A. M. 2012. Immunogenicity and efficacy of an anthrax/plague DNA fusion vaccine in a mouse model. FEMS Immunology & Medical Microbiology 65 (3) , pp. 505-509. 10.1111/j.1574-695X.2012.00974.x

Ingram, Rebecca and Baillie, Les 2012. It's in the genes! Human genetic diversity and the response to anthrax vaccines [Editorial]. Expert Review of Vaccines 11 (6) , pp. 633-635. 10.1586/erv.12.41

Baillie, Les and Theriault, Steven 2012. Control of infectious bioagents. In: Fraise, Adam, Maillard, Jean-Yves and Sattar, Syed eds. Russell, Hugo & Ayliffe's Principles and Practice of Disinfection, Preservation & Sterilization, Oxford: Wiley-Blackwell, pp. 576-588. (10.1002/9781118425831.ch23)

Brenneman, Karen E., Doganay, Mehmet, Akmal, Arya, Goldman, Stanley, Galloway, Darrell R., Mateczun, Alfred J., Cross, Alan S. and Baillie, Les 2011. The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax. FEMS Immunology & Medical Microbiology 62 (2) , pp. 164-172. 10.1111/j.1574-695X.2011.00800.x

Mett, V., Chichester, J. A., Stewart, M. L., Musiychuk, K., Bi, H., Reifsnyder, C. J., Hull, A. K., Albrecht, M. T., Goldman, S., Baillie, Les and Yusibov, V. 2011. A non-glycosylated, plant-produced human monoclonal antibody against anthrax protective antigen protects mice and non-human primates from B. anthracis spore challenge. Human Vaccines 7 , pp. 183-190. 10.4161/hv.7.0.14586

Baillie, Les, Dyson, H. and Simpson, A. 2011. Dual use of biotechnology. In: Singer, Peter, Callahan, Dan and Chadwick, Ruth F. eds. Encyclopedia of Applied Ethics, London: Academic Press Inc,

Porasuphatana, S., Cao, G. L., Tsai, P., Tavakkoli, F., Huwar, T., Baillie, Les, Cross, A. S., Shapiro, P. and Rosen, G. M. 2010. Bacillus Anthracis Endospores Regulate Ornithine Decarboxylase and Inducible Nitric Oxide Synthase Through ERK1/2 and p38 Mitogen-Activated Protein Kinases. Current Microbiology 61 (6) , pp. 567-573. 10.1007/s00284-010-9654-x

Baillie, Les, Huwar, Theresa B., Moore, Stephen, Mellado-Sanchez, Gabriela, Rodriguez, Liliana, Neeson, Brendan N., Flick-Smith, Helen C., Jenner, Dominic C., Atkins, Helen S., Ingram, Rebecca J., Altmann, Danny M., Nataro, James P. and Pasetti, Marcela F. 2010. An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor. Vaccine 28 (41) , pp. 6740-6748. 10.1016/j.vaccine.2010.07.075

Ramirez, K., Ditamo, Y., Galen, J. E., Baillie, Les and Pasetti, M. F. 2010. Mucosal priming of newborn mice with S. Typhi Ty21a expressing anthrax protective antigen (PA) followed by parenteral PA-boost induces B and T cell-mediated immunity that protects against infection bypassing maternal antibodies. Vaccine 28 (37) , pp. 6065-6075. 10.1016/j.vaccine.2010.06.089

Ingram, R. J., Chu, K. K., Metan, G., Maillere, B., Doganay, M., Ozkul, Y., Dyson, H., Williamson, E. D., Baillie, Les, Kim, L. U., Ascough, S., Sriskandan, S. and Altmann, D. M. 2010. An Epitope of Bacillus anthracis Protective Antigen That Is Cryptic in Rabbits May Be Immunodominant in Humans [Letter]. Infection and Immunity 78 (5) , pp. 2353-2354. 10.1128/IAI.00072-10

Ingram, Rebecca J., Metan, Gökhan, Maillere, Bernard, Doganay, Mehmet, Ozkul, Yusuf, Kim, Louise U., Baillie, Les, Dyson, Hugh, Williamson, E. Diane, Chu, Karen K., Ascough, Stephanie., Moore, Steven, Huwar, Theresa B., Robinson, John H., Sriskandan, Shiranee and Altmann, Daniel M. 2010. Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes. Journal of Immunology 184 (7) , pp. 3814-3821. 10.4049/jimmunol.0901581

Vernazza, C., Lingard, B., Flick-Smith, H. C., Baillie, Les, Hill, J. and Atkins, H. S. 2009. Small protective fragments of the Yersinia pestis V antigen. Vaccine 27 (21) , pp. 2775-2780. 10.1016/j.vaccine.2009.03.011

Baillie, Les, Rodriguez, Ana L., Moore, Stephen, Atkins, Helen S., Feng, Chiguang, Nataro, James P. and Pasetti, Marcela F. 2008. Towards a human oral vaccine for anthrax: the utility of a Salmonella Typhi Ty21a-based prime-boost immunization strategy. Vaccine 26 (48) , pp. 6083-6091. 10.1016/j.vaccine.2008.09.010

Aslan, K., Previte, M. J. R., Zhang, Y. X., Gallagher, T., Baillie, Les and Geddes, C. D. 2008. Extraction and detection of DNA from Bacillus anthracis spores and the vegetative cells within 1 min. Analytical Chemistry (including News & Features) 80 (11) , pp. 4125-4132. 10.1021/ac800519r

Kang, T. J., Basu, S., Zhang, L., Thomas, K. E., Vogel, S. N., Baillie, Les and Cross, A. S. 2008. Bacillus anthracis spores and lethal toxin induce IL-1 beta via functionally distinct signaling pathways. European Journal of Immunology 38 (6) , pp. 1574-1584. 10.1002/eji.200838141

Basu, Subhendu, Kang, Tae Jin, Chen, Wilbur H., Fenton, Matthew J., Baillie, Les, Hibbs, Steve and Cross, Alan S. 2007. Role of Bacillus anthracis spore structures in macrophage cytokine responses. Infection and Immunity 75 (5) , pp. 2351-2358. 10.1128/IAI.01982-06

Stokes, Margaret G. M., Titball, Richard W., Neeson, Brendan N., Galen, James E., Walker, Nicola J., Stagg, Anthony J., Jenner, Dominic C., Thwaite, Joanne E., Nataro, James P., Baillie, Les and Atkins, Helen S. 2007. Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis. Infection and Immunity 75 (4) , pp. 1827-1834. 10.1128/IAI.01242-06

Albrecht, M. T., Li, H., Williamson, E. D., LeButt, C. S., Flick-Smith, H. C., Quinn, C. P., Westra, H., Galloway, D., Mateczun, A., Goldman, S., Groen, H. and Baillie, Les 2007. Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax. Infection and Immunity 75 (11) , pp. 5425-5433. 10.1128/iai.00261-07

Aslan, K., Previte, M. J. R., Zhang, Y. X., Baillie, Les and Geddes, C. D. 2007. Ultra-fast and sensitive DNA hybridization assays: Application to genomic anthrax detection in < 30 seconds. Biophysical Journal , 552A-552A.

Aslan, K., Zhang, Y. X., Hibbs, S., Baillie, Les, Previte, M. J. R. and Geddes, C. D. 2007. Microwave-accelerated metal-enhanced fluorescence: application to detection of genomic and exosporium anthrax DNA in < 30 seconds. Analyst 132 (11) , pp. 1130-1138. 10.1039/b707876e

Basu, S., Kang, T. J., Chen, W. H., Fenton, M. J., Baillie, Les, Hibbs, S. and Cross, A. S. 2007. Role of Bacillus anthracis spore structures in macrophage cytokine responses. Infection and Immunity 75 (5) , pp. 2351-2358. 10.1128/iai.01982-06

Hepburn, M. J., Dyson, E. H., Simpson, A. J. H., Brenneman, K. E., Bailey, N., Wilkinson, L., Hornby, R., Mateczun, A. J., Bell, M. G. and Baillie, Les 2007. Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine. Vaccine 25 (32) , pp. 6089-6097. 10.1016/j.vaccine.2007.05.018

Legutki, J. B., Nelson, M., Titball, R., Galloway, D. R., Mateczun, A. and Baillie, Les 2007. Analysis of peptide mimotopes of Burkholderia pseudomallei exopolysaccharide. Vaccine 25 (45) , pp. 7796-7805. 10.1016/j.vaccine.2007.08.045

Stokes, M. G. M., Titball, R. W., Neeson, B. N., Galen, J. E., Walker, N. J., Stagg, A. J., Jenner, D. C., Thwaite, J. E., Nataro, J. P., Baillie, Les and Atkins, H. S. 2007. Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B-anthracis. Infection and Immunity 75 (4) , pp. 1827-1834. 10.1128/iai.01242-06

Weaver, J., Kang, T. J., Raines, K., Cao, G. L., Hibbs, S., Tsai, P., Rosen, G., Cross, A. and Baillie, Les 2007. The protective role of bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide. The FASEB Journal 21 (5) , A624-A624.

Weaver, J., Kang, T. J., Raines, K. W., Cao, G. L., Hibbs, S., Tsai, P., Baillie, Les, Rosen, G. M. and Cross, A. S. 2007. Protective role of Bacillus anthracis exosporium in macrophage-mediated killing by nitric oxide. Infection and Immunity 75 (8) , pp. 3894-3901. 10.1128/iai.00283-07

Priest, Fergus G., Barker, Margaret, Baillie, Les, Holmes, Edward C. and Maiden, Martin C. J. 2004. Population. Journal of Bacteriology 186 (23) , pp. 7959-7970. 10.1128/JB.186.23.7959-7970.2004

Baillie, Les, Peterson, S.N, Read, T.D and Tourasse, N 2003. The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature 423 (6935) , pp. 81-86. 10.1038/nature01586

Baillie, Les, Hebdon, R., Flick-Smith, H. and Williamson, D. 2003. Characterisation of the immune response to the UK human anthrax vaccine. FEMS Immunology and Medical Microbiology 36 (1-2) , pp. 83-86. 10.1016/S0928-8244(03)00085-3

Williams, R. C., Rees, M. L., Jacobs, M. F., Pragai, Z., Thwaite, J. E., Baillie, Les, Emmerson, P. T. and Harwood, C. R. 2003. Production of Bacillus anthracis protective antigen is dependent on the extracellular chaperone, PrsA. Journal of Biological Chemistry 278 (20) , pp. 18056-18062. 10.1074/jbc.M301244200

Williamson, E. D., Bennett, A. M., Perkins, S. D., Beedham, R. J., Miller, J. and Baillie, Les 2002. Co-immunisation with a plasmid DNA cocktail primes mice against anthrax and plague. Vaccine 20 (23-24) , pp. 2933-2941. 10.1016/S0264-410X(02)00232-3

Flick-Smith, H. C., Eyles, J. E., Hebdon, R., Waters, E. L., Beedham, R. J., Stagg, T. J., Miller, J., Alpar, H. O., Baillie, Les and Williamson, E. D. 2002. Mucosal or parenteral administration of microsphere-associated Bacillus anthracis protective antigen protects against anthrax infection in mice. Infection and Immunity 70 (4) , pp. 2022-2028. 10.1128/IAI.70.4.2022-2028.2002

Thwaite, J. E., Baillie, Les, Carter, N. M., Stephenson, K., Rees, M., Harwood, C. R. and Emmerson, P. T. 2002. Optimization of the cell wall microenvironment allows increased production of recombinant Bacillus anthracis protective antigen from B-subtilis. Applied and Environmental Microbiology 68 (1) , pp. 227-234. 10.1128/AEM.68.1.227-234.2002

Baillie, Les 2001. The development of new vaccines against Bacillus anthracis. Journal of Applied Microbiology 91 (4) , pp. 609-613. 10.1046/j.1365-2672.2001.01498.x

Baillie, Les and Godfree, A. 2001. Dangerous Pathogens 2000, University of Plymouth, 4-7th September 2000 [Preface]. Journal of Applied Microbiology 91 (4) , p. 571. 10.1046/j.1365-2672.2001.01307.x

Baillie, Les 2000. Bacillus anthracis. In: Batt, C. A., Robinson, R. K. and Patel, P. D. eds. The Encyclopaedia of Food Microbiology, Academic Press, pp. 129-135.

Williamson, E. D., Beedham, R. J., Bennett, A. M., Perkins, S. D., Miller, J. and Baillie, Les 1999. Presentation of protective antigen to the mouse immune system: immune sequelae. Journal of Applied Microbiology 87 (2) , pp. 315-317. 10.1046/j.1365-2672.1999.00901.x

Zegers, N. D., Kluter, E., van der Stap, H., van Dura, E., van Dalen, P., Shaw, M. and Baillie, Les 1999. Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: towards the development of an oral vaccine against anthrax. Journal of Applied Microbiology 87 (2) , pp. 309-314. 10.1046/j.1365-2672.1999.00900.x

Baillie, Les, Fowler, K. and Turnbull, P. C. B. 1999. Human immune responses to the UK human anthrax vaccine. Journal of Applied Microbiology 87 (2) , pp. 306-308. 10.1046/j.1365-2672.1999.00899.x

Fowler, K., McBride, B. W., Turnbull, P. C. B. and Baillie, Les 1999. Immune correlates of protection against anthrax. Journal of Applied Microbiology 87 (2) , p. 305. 10.1046/j.1365-2672.1999.00898.x

Baillie, Les, Moore, P. and McBride, B. W. 1998. A heat-inducible Bacillus subtilis bacteriophage Phi 105 expression system for the production of the protective antigen of Bacillus anthracis. FEMS Microbiology Letters 163 (1) , pp. 43-47. 10.1111/j.1574-6968.1998.tb13024.x

McBride, B., Mogg, A., Telfer, J. L., Lever, M. S., Miller, J., Turnbull, P. C. B. and Baillie, Les 1998. Protective efficacy of a recombinant protective antigen against Bacillus anthracis challenge and assessment of immunological markers. Vaccine 16 (8) , pp. 810-817. 10.1016/S0264-410X(97)00268-5

Baillie, Les, Moir, A. and Manchee, R. 1998. The expression of the protective antigen of Bacillus anthracis in Bacillus subtilis. Journal of Applied Microbiology 84 (5) , pp. 741-746. 10.1046/j.1365-2672.1998.00405.x

Miller, J., McBride, B. W., Manchee, R. J., Moore, P. and Baillie, Les 1998. Production and purification of recombinant protective antigen and protective efficacy against Bacillus anthracis. Letters in Applied Microbiology 26 (1) , pp. 56-60. 10.1046/j.1472-765X.1998.00274.x

Baillie, Les, Jones, M. N., Turnbull, P. C. B. and Manchee, R. J. 1995. Evaluation of the Biolog system for the identification of Bacillus anthracis. Letters in Applied Microbiology 20 (4) , pp. 209-211. 10.1111/j.1472-765X.1995.tb00429.x

Baillie, Les, Johnson, M. and Manchee, R. J. 1994. Evaluation of Bacillus subtilis strain IS53 for the production of Bacillus anthracis protective antigen. Letters in Applied Microbiology 19 (4) , pp. 225-227. 10.1111/j.1472-765X.1994.tb00949.x

Baillie, Les, Wade, J. J. and Casewell, M. W. 1993. Colonial variation in vancomycin resistant Enterococcus faecium. Journal of Clinical Pathology 46 (5) , pp. 474-475. 10.1136/jcp.46.5.474

Wade, J., Baillie, Les, Rolando, N. and Casewell, M. 1992. Pristinamycin for Enterococcus faecium resistant to vancomycin and gentamicin. Lancet 339 (8788) , pp. 312-313. 10.1016/0140-6736(92)91391-K

Baillie, Les 1990. Rapid identification of Klebsiella [Letter]. Journal of Clinical Pathology 43 (10) , p. 875. 10.1136/jcp.43.10.875-b

Baillie, Les 1989. Ciproflaxacin-resistant pseudomonas-aeruginosa strain. Medical Laboratory Sciences 46 (1) , pp. 92-93.

Baillie, Les 1987. A survey of the incidence of penicillin-resistant beta-lactamase-negative strains of staphylococcus-aureus. Medical Laboratory Sciences 44 (3) , pp. 285-286.

Baillie, Les 1987. Chlorhexidine resistance among bacteria isolated from urine of catheterized patients [Short report]. Journal of Hospital Infection 10 (1) , pp. 83-86. 10.1016/0195-6701(87)90037-5

Baillie, Les 1986. Routine screening of catheter urine specimens for chlorhexidine resistant organisms. Medical Laboratory Sciences 43 (3) , pp. 284-285.