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Number of items: 35.

Smallwood, Taylor B., Giacomin, Paul R., Loukas, Alex, Mulvenna, Jason P., Clark, Richard J. and Miles, John James 2017. Helminth immunomodulation in autoimmune disease. Frontiers in Immunology 10.3389/fimmu.2017.00453
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Laugel, Bruno, Lloyd, Angharad, Meermeier, Erin W., Crowther, Michael D., Connor, Thomas, Dolton, Garry Michael, Miles, John James, Burrows, Scott R., Gold, Marielle C., Lewinsohn, David M. and Sewell, Andrew K. 2016. Engineering of isogenic cells deficient for MR1 with a CRISPR/Cas9 lentiviral system: tools to study microbial antigen processing and presentation to human MR1-restricted T cells. The Journal of Immunology 197 (3) , pp. 971-982. 10.4049/jimmunol.1501402
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Smith, Corey, Brennan, Rebekah M., Tey, Siok-Keen, Smyth, Mark J., Burrows, Scott R., Miles, John, Hill, Geoffrey R., Khanna, Rajiv and Frueh, K. 2016. Coinfection with human cytomegalovirus genetic variants in transplant recipients and its impact on antiviral T cell immune reconstitution. Journal of Virology 90 (16) , pp. 7497-7507. 10.1128/JVI.00297-16
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Theaker, Sarah M., Rius Rafael, Cristina, Greenshields-Watson, Alexander, Lloyd, Angharad, Trimby, Andrew R., Fuller, Anna, Miles, John James, Cole, David, Peakman, Mark, Sewell, Andrew K. and Dolton, Garry Michael 2016. T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones. Journal of Immunological Methods 430 , pp. 43-50. 10.1016/j.jim.2016.01.014
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Blake, S. J., Stannard, K., Liu, J., Allen, S., Yong, M. C. R., Mittal, D., Aguilera, A. R., Miles, John, Lutzky, V. P., de Andrade, L. F., Martinet, L., Colonna, M., Takeda, K., Ku hnel, F., Gurlevik, E., Bernhardt, G., Teng, M. W. L. and Smyth, M. J. 2016. Suppression of metastases using a new lymphocyte checkpoint target for cancer immunotherapy. Cancer Discovery 6 (4) , pp. 446-459. 10.1158/2159-8290.CD-15-0944

Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, John James, Purcell, A. W., Rossjohn, Jamie, Gras, S. and Burrows, S. R. 2015. T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells. The Journal of Immunology 194 (10) , pp. 4668-4675. 10.4049/jimmunol.1500233

Neller, Michelle A., Ladell, Kristin Ingrid, McLaren, James Edward, Matthews, Katherine K., Gostick, Emma, Pentier, Johanne, Dolton, Garry Michael, Schauenburg, Andrea J. A., Koning, Dan, Fontaine Costa, Ana Isabel C. A., Watkins, Thomas S., Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly Louise, Clement, Mathew, Wooldridge, Linda, Cole, David, van Baarle, Debbie, Sewell, Andrew K., Burrows, Scott R., Price, David and Miles, John James 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93 , pp. 625-633. 10.1038/icb.2015.17
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Rossjohn, Jamie, Gras, Stephanie, Miles, John James, Turner, Stephen J., Godfrey, Dale I. and McCluskey, James 2015. T cell antigen receptor recognition of antigen-presenting molecules. Annual Review of Immunology 33 (1) , pp. 169-200. 10.1146/annurev-immunol-032414-112334

Skowera, Ania, Ladell, Kristin, McLaren, James E., Dolton, Garry, Matthews, Katherine K., Gostick, Emma, Kronenberg-Versteeg, Deborah, Eichmann, Martin, Knight, Robin R., Heck, Susanne, Powrie, Jake, Bingley, Polly J., Dayan, Colin M., Miles, John J., Sewell, Andrew K., Price, David A. and Peakman, Mark 2015. β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure. Diabetes 64 (3) , pp. 916-925. 10.2337/db14-0332
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Gold, M. C., McLaren, James Edward, Reistetter, J. A., Smyk-Pearson, S., Ladell, Kristin, Swarbrick, G. M., Yu, Y. Y. L., Hansen, T. H., Lund, O., Nielsen, M., Gerritsen, B., Kesmir, C., Miles, John James, Lewinsohn, D. A., Price, David and Lewinsohn, D. M. 2014. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. Journal of Experimental Medicine 211 (8) , pp. 1601-1610. 10.1084/jem.20140507
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Dolton, Garry Michael, Lissina, A., Skowera, A., Ladell, Kristin Ingrid, Tungatt, Katie, Jones, Emma, Kronenberg-Versteeg, D., Akpovwa, Hephzibah, Pentier, Johanne, Holland, C. J., Godkin, Andrew James, Cole, David, Neller, M. A., Miles, John James, Price, David, Peakman, M. and Sewell, Andrew K. 2014. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clinical and Experimental Immunology 177 (1) , pp. 47-63. 10.1111/cei.12339
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Smith, Corey, Gras, Stephanie, Brennan, Rebekah M., Bird, Nicola L., Valkenburg, Sophie A., Twist, Kelly-Anne, Burrows, Jacqueline M., Miles, John James, Chambers, Daniel, Bell, Scott, Campbell, Scott, Kedzierska, Katherine, Burrows, Scott R, Rossjohn, Jamie and Khanna, Rajiv 2014. Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Scientific Reports 4 , 3993. 10.1038/srep03993

Tungatt, Katie, Bianchi, Valentina, Crowther, Michael D., Powell, Wendy, Schauenburg, Andrea J. A., Trimby, Andrew R., Donia, M., Miles, John James, Holland, Christopher J., Cole, David, Godkin, Andrew James, Peakman, M., Straten, P. T., Svane, I. M., Sewell, Andrew K. and Dolton, Garry Michael 2014. Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. The Journal of Immunology 194 (1) , pp. 463-474. 10.4049/jimmunol.1401785
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Burrows, Scott R. and Miles, John James 2013. Immune parameters to consider when choosing T-Cell receptors for therapy. Frontiers in Immunology 4 , 229. 10.3389/fimmu.2013.00229

Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S., Birkinshaw, R., Beddoe, T., Corbett, A., Liu, L., Miles, John James, Meehan, B., Reantragoon, R., Sandoval-Romero, M., Sullivan, L., Brooks, A., Chen, Z., Fairlie, D., McCluskey, J. and Rossjohn, Jamie 2013. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications 4 (2142) 10.1038/ncomms3142

Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland, A., Chen, Z., Sullivan, L. C., Burrows, J. M., Miles, John James, Brennan, R. M., Gras, S., Khanna, R., Brooks, A. G., McCluskey, J., Purcell, A. W., Rossjohn, Jamie and Burrows, S. R. 2013. HLA peptide length preferences control CD8+ T cell responses. The Journal of Immunology 191 (2) , pp. 561-571. 10.4049/jimmunol.1300292

Pentier, Johanne M., Sewell, Andrew K. and Miles, John James 2013. Advances in T-Cell Epitope Engineering. Frontiers in Immunology 4 , 133. 10.3389/fimmu.2013.00133
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Madura, Florian, Rizkallah, Pierre, Miles, Kim Michelle, Holland, Christopher J., Bulek, Anna Marta, Fuller, Anna, Schauenburg, Andrea J. A., Miles, John James, Liddy, Nathaniel, Sami, M., Li, Y., Hossain, M., Baker, B. M., Jakobsen, B. K., Sewell, Andrew K. and Cole, David 2013. T-cell receptor specificity maintained by altered thermodynamics. Journal of Biological Chemistry 288 (26) , pp. 18766-18775. 10.1074/jbc.M113.464560

Liu, Y., Miles, John James, Neller, M., Gostick, E., Price, David, Purcell, A., McCluskey, J., Burrows, S., Rossjohn, Jamie and Gras, S. 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22) , pp. 15442-15454. 10.1074/jbc.M112.447185
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Motozono, Chihiro, Miles, John J., Hasan, Zafrul, Gatanaga, Hiroyuki, Meribe, Stanley C., Price, David, Oka, Shinichi, Sewell, Andrew K. and Ueno, Takamasa 2013. CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope. PLoS ONE 8 (6) , e66152. 10.1371/journal.pone.0066152
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Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David, Burrows, Scott R., Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Koning, D., Costa, A. I., Hoof, I., Miles, John James, Nanlohy, N. M., Ladell, Kristin Ingrid, Matthews, Katherine K., Venturi, V., Schellens, I. M. M., Borghans, J. A. M., Kesmir, C., Price, David and van Baarle, D. 2013. CD8+ TCR repertoire formation is guided primarily by the peptide component of the antigenic complex. The Journal of Immunology 190 (3) , pp. 931-939. 10.4049/jimmunol.1202466

Ekeruche, Julia, Clement, Mathew, Cole, David, Edwards, Emily S. J., Ladell, Kristin Ingrid, Miles, John James, Matthews, Katherine K., Fuller, Anna, Lloyd, Katy A., Madura, Florian, Dolton, Garry Michael, Pentier, Johanne, Lissina, Anna, Gostick, Emma, Baxter, Tiffany K., Baker, Brian M., Rizkallah, Pierre, Price, David, Wooldridge, Linda and Sewell, Andrew K. 2012. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. Journal of Biological Chemistry 287 (44) , pp. 37269-37281. 10.1074/jbc.M112.386409

Bulek, Anna Marta, Cole, David, Skowera, Ania, Dolton, Garry Michael, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John James, Gostick, Emma, Price, David, Drijfhout, Jan W., Knight, Robin R., Huang, Guo C., Lissin, Nikolai, Molloy, Peter E., Wooldridge, Linda, Jakobsen, Bent K., Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre and Sewell, Andrew K. 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Wooldridge, Linda, Ekeruche, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John James, Tan, Mai Ping, Dolton, Garry Michael, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David, Peakman, Mark and Sewell, Andrew K. 2012. A single autoimmune T cell receptor recognizes more than a million different peptides. Journal of Biological Chemistry 287 (2) , pp. 1168-1177. 10.1074/jbc.M111.289488

Bridgeman, John S., Sewell, Andrew K., Miles, John James, Price, David A. and Cole, David K. 2012. Structural and biophysical determinants of ab T-cell antigen recognition. Immunology 135 (1) , pp. 9-18. 10.1111/j.1365-2567.2011.03515.x

Clement, Mathew, Ladell, Kristin Ingrid, Ekeruche, Julia, Miles, John James, Edwards, Emily, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy, Godkin, Andrew James, Burrows, Scott R., Price, David, Sewell, Andrew K. and Wooldridge, Linda 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2) , pp. 654-663. 10.4049/jimmunol.1003941

Miles, Kim Michelle, Miles, John James, Madura, Florian, Sewell, Andrew K. and Cole, David 2011. Real time detection of peptide-MHC dissociation reveals that improvement of primary MHC-binding residues can have a minimal, or no, effect on stability. Molecular Immunology 48 (4) , pp. 728-732. 10.1016/j.molimm.2010.11.004

Miles, John James, Douek, Daniel C. and Price, David 2011. Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination. Immunology and Cell Biology 89 (3) , pp. 375-387. 10.1038/icb.2010.139

Cole, David, Edwards, Emily, Wynn, Katherine, Clement, Mathew, Miles, John James, Ladell, Kristin Ingrid, Ekeruche, Julia, Gostick, Emma, Adams, Katherine J., Skowera, Ania, Peakman, Mark, Wooldridge, Linda, Price, David A. and Sewell, Andrew K. 2010. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. The Journal of Immunology 185 (4) , pp. 2600-2610. 10.4049/jimmunol.1000629

Wooldridge, Linda, Clement, Mathew, Lissina, Anna, Edwards, Emily, Ladell, Kristin Ingrid, Ekeruche, Julia, Hewitt, R. E., Laugel, Bruno Frederic, Gostick, Emma, Cole, David, Debets, R., Berrevoets, C., Miles, John James, Burrows, S. R., Price, David A. and Sewell, Andrew K. 2010. MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. Journal of Immunology 184 (7) , pp. 3357-3366. 10.4049/jimmunol.0902398

Miles, John James, Bulek, Anna Marta, Cole, David, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David, Rizkallah, Pierre and Sewell, Andrew K. 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) , e1001198. 10.1371/journal.ppat.1001198
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Cole, David, Yuan, Fang, Rizkallah, Pierre, Miles, John James, Gostick, Emma, Price, David, Gao, George F., Jakobsen, Bent K. and Sewell, Andrew K. 2009. Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. Journal of Biological Chemistry 284 (40) , 27281-27289. 10.1074/jbc.M109.022509

Zhang, Yu, Kwan, Alan Shu Khen and Miles, John James 2008. Using generative representations for structural design. Presented at: Intelligent Computing in Engineering 2008 Conference: 15th workshop of the European Group for Intelligent Computing in Engineering (EG-ICE), Plymouth, UK, 2-4 July 2008. Published in: Rafiq, Y., de Wilde, P. and Borthwick, M. eds. Proceedings: Intelligent Computing in Engineering 2008 Conference. Plymouth: American Society of Civil Engineers (ASCE), pp. 36-45.

This list was generated on Sat Sep 23 09:46:02 2017 BST.