ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Number of items: 39.
Kukharsky, Michail S., Ninkina, Natalia N., An, Haiyan, Telezhkin, Vsevolod, Wei, Wenbin, Rabesahala de Meritens, Camille, Cooper-Knock, Johnathan, Nakagawa, Shinichi, Hirose, Tetsuro, Buchman, Vladimir and Shelkovnikova, Tatyana
2020.
Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice.
Translational Psychiatry
10
, 171.
10.1038/s41398-020-0854-2
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An, Haiyan and Shelkovnikova, Tatyana A
2019.
Stress granules regulate paraspeckles: RNP granule continuum at work.
Cell Stress
3
(12)
, pp. 385-387.
10.15698/cst2019.12.207
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Shelkovnikova, Tatyana, An, Haiyan, Skelt, Lucy, Tregoning, John S, Humphreys, Ian R and Buchman, Vladimir L
2019.
Antiviral immune response as a trigger of FUS proteinopathy in amyotrophic lateral sclerosis.
Cell Reports
29
(13)
, 4496-4508.e4.
10.1016/j.celrep.2019.11.094
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An, Haiyan, Tan, Jing Tong and Shelkovnikova, Tatyana A.
2019.
Stress granules regulate stress-induced paraspeckle assembly.
Journal of Cell Biology
218
(12)
, pp. 4127-4140.
10.1083/jcb.201904098
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Park, Sangeun, Park, Sei-Kyoung, Watanabe, Naruaki, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Shelkovnikova, Tatyana A. and Liebman, Susan W.
2019.
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
PLoS Genetics
15
(8)
, e1008308.
10.1371/journal.pgen.1008308
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| An, Haiyan, Skelt, Lucy, Notaro, Antonietta, Highley, J. Robin, Fox, Archa H., La Bella, Vincenzo, Buchman, Vladimir L. and Shelkovnikova, Tatyana A. 2019. ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles. Acta Neuropathologica Communications 7 , 7. 10.1186/s40478-019-0658-x |
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An, Haiyan, Williams, Non G and Shelkovnikova, Tatyana A.
2018.
NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?
Non-coding RNA Research
3
(4)
, pp. 243-252.
10.1016/j.ncrna.2018.11.003
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| Shelkovnikova, Tatyana A., Kukharsky, Michail S., An, Haiyan, Dimasi, Pasquale, Alexeeva, Svetlana, Shabir, Osman, Heath, Paul R. and Buchman, Vladimir L. 2018. Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis. Molecular Neurodegeneration 13 , 30. 10.1186/s13024-018-0263-7 |
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| Shelkovnikova, Tatyana, Dimasi, Pasquale, Kukharsky, Michail S., An, Haiyan, Quintiero, Annamaria, Schirmer, Claire, Buée, Luc, Galas, Marie-Christine and Buchman, Vladimir L. 2017. Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly. Cell Death and Disease 8 , e2788. 10.1038/cddis.2017.199 |
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| Dimasi, Pasquale, Quintiero, Annamaria, Shelkovnikova, Tatyana and Buchman, Vladimir L. 2017. Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose. Scientific Reports 7 , 44088. 10.1038/srep44088 |
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| Scekic-Zahirovic, Jelena, Sendscheid, Oliver, El Oussini, Hajer, Jambeau, Mélanie, Sun, Ying, Mersmann, Sina, Wagner, Marina, Dieterle, Stéphane, Sinniger, Jerome, Dirrig-Grosch, Sylvie, Drenner, Kevin, Birling, Marie‐Christine, Qiu, Jinsong, Zhou, Yu, Li, Hairi, Fu, Xiang‐Dong, Rouaux, Caroline, Shelkovnikova, Tatyana, Witting, Anke, Ludolph, Albert C., Kiefer, Friedemann, Storkebaum, Erik, Lagier-Tourenne, Clotilde and Dupuis, Luc 2016. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO Journal 35 (10) , pp. 1077-1097. 10.15252/embj.201592559 |
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| Van De Pette, Matthew, Tunster, Simon J., McNamara, Grainne I., Shelkovnikova, Tatyana, Millership, Steven, Benson, Lindsay, Peirson, Stuart, Christian, Mark, Vidal-Puig, Antonio and John, Rosalind M. 2016. Cdkn1c boosts the development of brown adipose tissue in a murine model of Silver Russell Syndrome. PLoS Genetics 12 (3) , e1005916. 10.1371/journal.pgen.1005916 |
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| Ninkina, Natalia, Connor-Robson, Natalie, Ustyugov, Alexey A., Tarasova, Tatiana, Shelkovnikova, Tatyana and Buchman, Vladimir L. 2015. A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression. Scientific Reports 5 , 16615. 10.1038/srep16615 |
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| Kukharsky, Michail S., Quintiero, Annamaria, Matsumoto, Taisei, Matsukawa, Koji, An, Haiyan, Hashimoto, Tadafumi, Iwatsubo, Takeshi, Buchman, Vladimir L. and Shelkovnikova, Tatyana A. 2015. Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis. Molecular Neurodegeneration 10 , 20. 10.1186/s13024-015-0014-y |
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| Peters, Owen Morgan, Shelkovnikova, Tatyana, Highley, John Robin, Cooper-Knock, Johnathan, Hortobágyi, Tibor, Troakes, Claire, Ninkina, Natalia and Buchman, Vladimir L. 2015. Gamma-synuclein pathology in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology 2 (1) , pp. 29-37. 10.1002/acn3.143 |
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| Robinson, Hannah, Deykin, Alexey V., Bronovitsky, Evgeny V., Ovchinnikov, Ruslan K., Ustyugov, Alexey A., Shelkovnikova, Tatyana, Kukharsky, Michail S., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Bachurin, Sergey O., Buchman, Vladimir L. and Ninkina, Natalia 2015. Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16 (5-6) , pp. 402-409. 10.3109/21678421.2015.1040994 |
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| Shelkovnikova, Tatyana A., Robinson, Hannah K., Southcombe, Joshua A., Ninkina, Natalia and Buchman, Vladimir L. 2014. Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms. Human Molecular Genetics 23 (19) , pp. 5211-5226. 10.1093/hmg/ddu243 |
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| Shelkovnikova, Tatyana, Robinson, Hannah, Troakes, C., Ninkina, Natalia and Buchman, Vladimir 2014. Compromised paraspeckle formation as a pathogenic factor in FUSopathies. Human Molecular Genetics 23 (9) , pp. 2298-2312. 10.1093/hmg/ddt622 |
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| Shelkovnikova, Tatyana, Ustiugov, A. A., Kokhan, V. S., Tarasova, T. V., Medvedeva, V. K., Khritankova, I. V., Bahcurin, S. O. and Ninkina, Natalia 2014. Study into molecular targets of a neuroprotective compound dimebon using a transgenic mice line. Biomeditsinskaia khimiia 60 (3) , pp. 354-363. |
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| Deikin, A V, Kovrazhkina, E A, Ovchinnikov, R K, Bronovitskii, E V, Razinskia, O D, Smirnov, A P, Ermolkevich, T G, Eliakov, A B, Popov, A N, Fedorov, E N, Lytkina, O A, Kukharskii, M S, Tarasova, T V, Shelkovnikova, Tatyana A., Ustiugov, A A, Ninkina, Natalia, Gol'dman, I L, Sadchikova, E R, Baruchin, S O and Skvortsova, V I 2014. A mice model of amyotrophic lateral sclerosis expressing mutant human FUS protein. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 114 (8) , pp. 62-69. |
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| Shelkovnikova, Tatyana A. 2013. Modelling FUSopathies: focus on protein aggregation. Biochemical Society Transactions 41 (6) , pp. 1613-1617. 10.1042/BST20130212 |
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| Shelkovnikova, Tatyana, Robinson, Hannah, Connor-Robson, Natalie and Buchman, Vladimir L. 2013. Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm. Cell Cycle 12 (19) , pp. 3194-3202. 10.4161/cc.26241 |
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| Shelkovnikova, Tatyana, Peters, Owen Morgan, Deykin, Alexey V., Connor-Robson, Natalie, Robinson, Hannah, Ustyugov, Aleksey, Bachurin, Sergey O., Ermolkevich, Tatyana G., Goldman, Igor L., Sadchikova, Elena R., Kovrazhkina, Elena A., Skvortsova, Veronica I., Ling, Shuo-Chien, Da Cruz, Sandrine, Parone, Philippe A., Buchman, Vladimir L. and Ninkina, Natalia 2013. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. Journal of Biological Chemistry 288 (35) , pp. 25266-25274. 10.1074/jbc.M113.492017 |
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| Peters, Owen Morgan, Shelkovnikova, Tatyana, Tarasova, Tatiana, Springe, Signe, Kukharsky, Michail S., Smith, Gaynor A., Brooks, Simon Philip, Kozin, Sergey A., Kotelevtsev, Yury, Bachurin, Sergey O., Ninkina, Natalia and Buchman, Vladimir L. 2013. Chronic administration of dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease 36 (3) , pp. 589-596. 10.3233/JAD-130071 |
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| Bachurin, S.O, Ninkina, Natalia, Tarasova, T.V, Shelkovnikova, Tatyana, Kovrazhkina, E.A, Smirnov, A.P, Razinskaya, O and Skvortsova, V.I 2013. Modeling of lateral amyotrophic sclerosis: A non-genetic method. Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova 113 (9) , pp. 86-89. |
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| Kokhan, V. S., Van'kin, G. I., Ninkina, Natalia, Shelkovnikova, Tatyana and Bachurin, S. O. 2012. Impaired spatial and working memory in ageing mice with targeted inactivation of α-synuclein gene. Doklady Biological Sciences 441 (1) , pp. 354-356. 10.1134/S0012496611060081 |
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| Peters, Owen Morgan, Millership, Steven, Shelkovnikova, Tatyana, Soto, Ileana, Keeling, Lora, Hann, Anthona, Marsh-Armstrong, Nicholas, Buchman, Vladimir L. and Ninkina, Natalia 2012. Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis. Neurobiology of Disease 48 (1) , pp. 124-131. 10.1016/j.nbd.2012.06.016 |
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| Shelkovnikova, Tatyana, Ninkina, Natalia and Buchman, Vladimir L. 2012. In Vivo properties of mutant FUS variants. Febs Journal 279 (Supp1) , p. 446. 10.1111/j.1742-4658.2010.08705.x |
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| Kokhan, V. S., Bolkunov, A. V., Ustiugov, A. A., Van'kin, G. I., Shelkovnikova, Tatyana, Redkozubova, O. M., Strekalova, T. V., Buchman, Vladimir L., Ninkina, Natalia and Bachurin, S. O. 2012. Targeted inactivation of the gene encoding gamma-synuclein affects anxiety levels and investigative activity in mice. Neuroscience and Behavioral Physiology 42 (6) , pp. 575-581. 10.1007/s11055-012-9603-1 |
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| Bachurin, Sergey O., Shelkovnikova, Tatyana, Ustyugov, Alexey A., Peters, Owen Morgan, Khritankova, Ina, Afanasieva, Marina A., Tarasova, Tatyana V., Alentov, Igor I., Buchman, Vladimir L. and Ninkina, Natalia 2012. Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice. Neurotoxicity Research 22 (1) , pp. 33-42. 10.1007/s12640-011-9299-y |
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| Shelkovnikova, Tatyana, Kulikova, A.A., Tsvetkov, F.O., Peters, O., Bachurin, S.O., Bukhman, V.L. and Ninkina, N.N. 2012. [Proteinopathies--forms of neurodegenerative disorders with protein aggregation-based pathology]. Molekulyarnaya Biologiya 46 (3) , pp. 402-415. |
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| Ustyugov, A. A., Shelkovnikova, Tatyana, Kokhan, V. S., Khritankova, I. V., Peters, Owen Morgan, Buchman, Vladimir L., Bachurin, S. O. and Ninkina, Natalia 2012. Dimebon reduces the levels of aggregated amyloidogenic protein forms in detergent-insoluble fractions in vivo. Bulletin of Experimental Biology and Medicine 152 (6) , pp. 731-733. 10.1007/s10517-012-1618-7 |
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| Shelkovnikova, Tatyana, Kulikova, A. A., Tsvetkov, Ph. O., Peters, Owen Morgan, Bachurin, S. O., Buchman, Vladimir L. and Ninkina, Natalia 2012. Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology. Molecular Biology 46 (3) , pp. 362-374. 10.1134/S0026893312020161 |
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| Skrovtsova, V. I., Bachurin, S. O., Razinskaia, O. D., Smirnov, A. P., Kovrazhkina, E. A., Pochigaeva, K. I., Ninkina, Natalia, Shelkovnikova, Tatyana and Ustigiuov, A. A. 2011. New aspects of the pathogenesis of lateral amyotrophic sclerosis. Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova 111 (2) , pp. 4-9. |
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| Shelkovnikova, Tatyana, Ustyugov, A. A., Smirnov, A. P., Skvortsova, V. I., Buchman, Vladimir L., Bachurin, S. O. and Ninkina, Natalia 2011. FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein. Doklady Biochemistry and Biophysics 438 (1) , pp. 123-126. 10.1134/S1607672911030045 |
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| Shelkovnikova, Tatyana, Ustyugov, Alexey, Millership, Steven, Peters, Owen Morgan, Anichtchik, Oleg, Spillantini, Maria Grazia, Buchman, Vladimir L., Bachurin, Sergey and Ninkina, Natalia 2011. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice. Neurodegenerative Diseases 8 (6) , pp. 430-437. 10.1159/000324989 |
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| Ninkina, Natalia and Shelkovnikova, Tatyana 2011. Targeted inactivation of gamma-synuclein gene affects anxiety and exploratory behaviour of mice. Zhurnal vysshe nervno deiatelnosti imeni I P Pavlova 6 (1) , pp. 85-93. |
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| Bachurin, S. O., Ustyugov, A. A., Peters, O., Shelkovnikova, Tatyana, Buchman, Vladimir L. and Ninkina, Natalia 2009. Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds. Doklady Biochemistry and Biophysics 428 (1) , pp. 235-238. 10.1134/S1607672909050032 |
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