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Number of items: 34.

Ouaray, Zahra, Benner, Steven A., Georgiadis, Millie M. and Richards, Nigel G. J. 2020. Building better polymerases: Engineering the replication of expanded genetic alphabets. Journal of Biological Chemistry 295 (50) , pp. 17046-17059. 10.1074/jbc.REV120.013745

Radadiya, Ashish, Zhu, Wen, Coricello, Adriana, Alcaro, Stefano and Richards, Nigel G. J. 2020. Improving the treatment of acute lymphoblastic leukemia. Biochemistry 59 (35) , pp. 3193-3200. 10.1021/acs.biochem.0c00354

Gao, Sisi, Radadiya, Ashish, Li, Wenbo, Liu, Huanting, Zhu, Wen, de Crécy-Lagard, Valérie, Richards, Nigel G. J. and Naismith, James H. 2020. Uncovering the chemistry of C–C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex. Chemical Communications 56 (55) , pp. 7617-7620. 10.1039/D0CC02834G

Eberlein, Lukas, Beierlein, Frank R., van Eikema Hommes, Nico J.R., Radadiya, Ashish, Heil, Jochen, Benner, Steven A., Clark, Timothy, Kast, Stefan M. and Richards, Nigel G. J. 2020. Tautomeric equilibria of nucleobases in the hachimoji expanded genetic alphabet. Journal of Chemical Theory and Computation 16 (4) , pp. 2766-2777. 10.1021/acs.jctc.9b01079

Zhu, Wen, Liu, Xuan, Hughes, Margaret, de Crécy-Lagard, Valérie and Richards, Nigel G. J. 2020. Whole-genome sequence of Streptomyces kaniharaensis Shomura and Niida SF-557. Microbiology Resource Announcements 9 (14) , e01434-19. 10.1128/MRA.01434-19

Ouaray, Zahra, Singh, Isha, Georgiadis, Millie M. and Richards, Nigel G. J. 2020. Building better enzymes: molecular basis of improved non-natural nucleobase incorporation by an evolved DNA polymerase. Protein Science 29 (2) 10.1002/pro.3762

Gao, Sisi, Liu, Huanting, de Crécy-Lagard, Valérie, Zhu, Wen, Richards, Nigel G. J. and Naismith, James H. 2019. PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis. Chemical Communications 55 (96) , pp. 14502-14505. 10.1039/C9CC06975E

Zhu, Wen, Radadiya, Ashish, Bisson, Claudine, Wenzel, Sabine, Nordin, Brian E., Martínez-Márquez, Francisco, Imasaki, Tsuyoshi, Sedelnikova, Svetlana E., Coricello, Adriana, Baumann, Patrick, Berry, Alexandria H., Nomanbhoy, Tyzoon K., Kozarich, John W., Jin, Yi, Rice, David W., Takagi, Yuichiro and Richards, Nigel G. J. 2019. Author correction: High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity. Communications Biology 2 (1) , 438. 10.1038/s42003-019-0690-1

Zhu, Wen, Radadiya, Ashish, Bisson, Claudine, Wenzel, Sabine, Nordin, Brian E., Martínez-Márquez, Francisco, Imasaki, Tsuyoshi, Sedelnikova, Svetlana E., Coricello, Adriana, Baumann, Patrick, Berry, Alexandria H., Nomanbhoy, Tyzoon K., Kozarich, John W., Jin, Yi, Rice, David W., Takagi, Yuichiro and Richards, Nigel G. J. 2019. High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity. Communications Biology 2 , 345. 10.1038/s42003-019-0587-z

Zhu, Wen, Reinhardt, Laurie A. and Richards, Nigel G. J. 2018. Second-shell hydrogen bond impacts transition-state structure in bacillus subtilis oxalate decarboxylase. Biochemistry 57 (24) , pp. 3425-3432. 10.1021/acs.biochem.8b00214

Jin, Yi, Molt Jr., Robert W., Pellegrini, Erika, Cliff, Matthew J., Bowler, Matthew W., Richards, Nigel G. J., Blackburn, G. Michael and Waltho, Jonathan P. 2017. Assessing the influence of mutation on GTPase transition states by using x-ray crystallography, 19F NMR, and DFT approaches. Angewandte Chemie International Edition 56 (33) , pp. 9732-9735. 10.1002/anie.201703074

Malhotra, Shashwat, Singh, Seema, Rana, Neha, Tomar, Shilpi, Bhatnagar, Priyanka, Gupta, Mohit, Singh, Suraj K., Singh, Brajendra K., Chhillar, Anil K., Prasad, Ashok K., Len, Christophe, Kumar, Pradeep, Gupta, Kailash C., Varma, Anjani J., Kuhad, Ramesh C., Sharma, Gainda L., Parmar, Virinder S. and Richards, Nigel 2017. Chemoenzymatic synthesis, nanotization and anti- aspergillus activity of optically enriched fluconazole analogues. Antimicrobial Agents and Chemotherapy 61 (8) , e00273-17. 10.1128/AAC.00273-17

Sheng, Xiang, Zhu, Wen, Huddleston, Jamison, Xiang, Dao Fen, Raushel, Frank M., Richards, Nigel G. J. and Himo, Fahmi 2017. A combined experimental-theoretical study of the ligW-catalyzed decarboxylation of 5-carboxyvanillate in the metabolic pathway for lignin degradation. ACS Catalysis 7 (8) , pp. 4968-4974. 10.1021/acscatal.7b01166

Richards, Nigel G. J. and Georgiadis, Millie M. 2017. Toward an expanded genome: structural and computational characterization of an artificially expanded genetic information system. Accounts of Chemical Research 50 (6) , pp. 1375-1382. 10.1021/acs.accounts.6b00655

Zhu, Wen and Richards, Nigel G. J. 2017. Biological functions controlled by manganese redox changes in mononuclear Mn-dependent enzymes. Essays in Biochemistry 61 (2) , pp. 259-270. 10.1042/EBC20160070

Blackburn, G. Michael, Cherfils, Jacqueline, Moss, Gerard P., Richards, Nigel G. J., Waltho, Jonathan P., Williams, Nicholas H. and Wittinghofer, Alfred 2017. How to name atoms in phosphates, polyphosphates, their derivatives and mimics, and transition state analogues for enzyme-catalysed phosphoryl transfer reactions (IUPAC Recommendations 2016). Pure and Applied Chemistry 89 (5) , pp. 653-675. 10.1515/pac-2016-0202

Molt, Robert, Georgiadis, Millie M. and Richards, Nigel G. J. 2017. Consecutive non-natural PZ nucleobase pairs in DNA impact helical structure as seen in 50 μs molecular dynamics simulations. Nucleic Acids Research 45 (7) , pp. 3643-3653. 10.1093/nar/gkx144

Jin, Yi, Richards, Nigel G. J., Waltho, Jonathan P. and Blackburn, G. Michael 2017. Metal fluorides as analogues for studies on phosphoryl transfer enzymes. Angewandte Chemie - International Edition 56 (15) , pp. 4110-4128. 10.1002/anie.201606474

Blackburn, George Michael, Jin, Yi, Richards, Nigel G.J. and Waltho, Jonathan P 2017. Metal fluorides as analogs for studies on phosphoryl transfer enzymes. Angewandte Chemie 129 (15) , pp. 4172-4192. 10.1002/ange.201606474

Kumar, Amit, Khan, Abdullah, Malhotra, Shashwat, Mosurkal, Ravi, Dhawan, Ashish, Pandey, Mukesh K., Singh, Brajendra K., Kumar, Rajesh, Prasad, Ashok K., Sharma, Sunil K., Samuelson, Lynne A., Cholli, Ashok L., Len, Christophe, Richards, Nigel G.J., Kumar, Jayant, Haag, Rainer, Watterson, Arthur C. and Parmar, Virinder S. 2016. Synthesis of macromolecular systems via lipase catalyzed biocatalytic reactions: applications and future perspectives. Chemical Society Reviews 45 (24) , pp. 6855-6887. 10.1039/C6CS00147E

Molt, Robert, Watson, Thomas, Bazanté, Alexandre P., Bartlett, Rodney J. and Richards, Nigel G.J. 2016. Gas phase RDX decomposition pathways using coupled cluster theory. Physical Chemistry Chemical Physics 18 (37) , pp. 26069-26077. 10.1039/C6CP05121A

Zhu, Wen, Easthon, Lindsey M., Reinhardt, Laurie A., Tu, Chingkuang, Cohen, Steven E., Silverman, David N, Allen, Karen N and Richards, Nigel G. J. 2016. Substrate binding mode and molecular basis of a specificity switch in oxalate decarboxylase. Biochemistry 85 (14) , pp. 2163-2173. 10.1021/acs.biochem.6b00043

Jin, Yi, Molt Jr, Robert W., Waltho, Jonathan P., Richards, Nigel G. J. and Blackburn, G. Michael 2016. 19F NMR and DFT analysis reveal structural and electronic transition state features for RhoA-catalyzed GTP hydrolysis. Angewandte Chemie International Edition 55 (10) , pp. 3318-3322. 10.1002/anie.201509477

Kumar, Prashant, Singh, Anil K., Bahadur, Vijay, Len, Christophe, Richards, Nigel G. J., Parmar, Virinder S., Van der Eycken, Erik V. and Singh, Brajendra K. 2016. Microwave-assisted, metal-free, base-mediated C-N bond formation/cleavage: synthesis of benzimidazo[1,2-a]quinazoline derivatives. ACS Sustainable Chemistry & Engineering 4 (4) , pp. 2206-2210. 10.1021/acssuschemeng.5b01669

Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D., Richards, Nigel G. J., Almo, Steven C. and Raushel, Frank M. 2016. Substrate distortion and the catalytic reaction mechanism of 5-carboxyvanillate decarboxylase. Journal of the American Chemical Society 138 (3) , pp. 826-836. 10.1021/jacs.5b08251

Zhu, Wen, Wilcoxen, Jarett, Britt, R. David and Richards, Nigel G. J. 2016. Formation of hexacoordinate Mn(III) in Bacillus subtilis oxalate decarboxylase requires catalytic turnover. Biochemistry 55 (3) , pp. 429-434. 10.1021/acs.biochem.5b01340

Sharma, Pramod K., Balwani, Sakshi, Mathur, Divya, Malhotra, Shashwat, Singh, Brajendra K., Prasad, Ashok K., Len, Christophe, Van der Eycken, Erik V., Ghosh, Balaram, Richards, Nigel G. J. and Parmar, Virinder S. 2016. Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids. Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6) , pp. 1520-1526. 10.3109/14756366.2016.1151015

Hettmer, Simone, Schinzel, Anna C., Tchessalova, Daria, Schneider, Michaela, Parker, Christina L., Bronson, Roderick T., Richards, Nigel G. J., Hahn, William C. and Wagers, Amy J. 2015. Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma. eLife 4 , e09436.. 10.7554/eLife.09436

Georgiadis, Millie M., Singh, Isha, Kellett, Whitney F., Hoshika, Shuichi, Benner, Steven A. and Richards, Nigel G. J. 2015. Structural basis for a six nucleotide genetic alphabet. Journal of the American Chemical Society 137 (21) , pp. 6947-6955. 10.1021/jacs.5b03482

Molt Jr., Robert W., Lecher, Alison M., Clark, Timothy, Bartlett, Rodney J. and Richards, Nigel G. J. 2015. Facile Csp2-Csp2 bond cleavage in oxalic acid-derived radicals. Journal of the American Chemical Society 137 (9) , pp. 3248-3252. 10.1021/ja510666r

Twahir, Umar T., Stedwell, Corey N., Lee, Cory T., Richards, Nigel G. J., Polfer, Nicolas C. and Angerhofer, Alexander 2015. Observation of superoxide production during catalysis of Bacillus subtilis oxalate decarboxylase at pH 4. Free Radical Biology and Medicine 80 , p. 59. 10.1016/j.freeradbiomed.2014.12.012

Miao, J, Richards, Nigel and Ge, H 2014. Rhodium-catalyzed direct synthesis of unprotected NH-sulfoximines from sulfoxides. Chemical Communications- Royal Society of Chemistry 50 (68) , pp. 9687-9689. 10.1039/c4cc04349a

Brunk, E, Kellett, W.F., Richards, Nigel and Rothlisberger, U 2014. A mechanochemical switch to control radical intermediates. Biochemistry 53 (23) , pp. 3830-3838. 10.1021/bi500050k

Campomanes, Pablo, Kellett, Whitney F., Easthon, Lindsey M., Ozarowski, Andrew, Allen, Karen N., Angerhofer, Alexander, Rothlisberger, Ursula and Richards, Nigel G. J. 2014. Assigning the EPR fine structure parameters of the Mn(II) centers in bacillus subtilis oxalate decarboxylase by site-directed mutagenesis and DFT/MM calculations. Journal of the American Chemical Society 136 (6) , pp. 2313-2323. 10.1021/ja408138f

This list was generated on Thu Mar 4 04:10:53 2021 GMT.

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