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Number of items: 26.

Carreira, A.C., Santos, T.C., Lone, M.A., Zupancic, E., Lloyd-Evans, Emyr, de Almeida, R.F.M., Hornemann, T. and Silva, L.C. 2019. Mammalian sphingoid bases: Biophysical, physiological and pathological properties. Progress in Lipid Research 75 , 100988. 10.1016/j.plipres.2019.100988
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Balogi, Zsolt, Multhoff, Gabrielle, Jensen, Thomas Kirkegaard, Lloyd-Evans, Emyr, Yamashima, Tetsumori, Jäättelä, Marja, Harwood, John L. and Vígh, László 2019. Hsp70 interactions with membrane lipids regulate cellular functions in health and disease. Progress in Lipid Research 74 , pp. 18-30. 10.1016/j.plipres.2019.01.004
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Morimoto, Marie, Waller-Evans, Helen, Ammous, Zineb, Song, Xiaofei, Strauss, Kevin A., Pehlivan, Davut, Gonzaga-Jauregui, Claudia, Puffenberger, Erik G., Holst, Charles R., Karaca, Ender, Brigatti, Karlla W., Maguire, Emily, Coban-Akdemir, Zeynep H., Amagata, Akiko, Lau, C. Christopher, Chepa-Lotrea, Xenia, Macnamara, Ellen, Tos, Tulay, Isikay, Sedat, Nehrebecky, Michele, Overton, John D., Klein, Matthew, Markello, Thomas C., Posey, Jennifer E., Adams, David R., Lloyd-Evans, Emyr, Lupski, James R., Gahl, William A. and Malicdan, May Christine V. 2018. Bi-allelic CCDC47 variants cause a disorder characterized by woolly hair, liver dysfunction, dysmorphic features, and global developmental delay. American Journal of Human Genetics 103 (5) , pp. 794-807. 10.1016/j.ajhg.2018.09.014
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Lange, Jenny, Haslett, Luke J., Lloyd-Evans, Emyr, Pocock, Jennifer M., Sands, Mark S., Williams, Brenda P. and Cooper, Jonathan D. 2018. Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis. Acta Neuropathologica Communications 6 (1) , 74. 10.1186/s40478-018-0575-4
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Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A., Platt, Nick, Davis, Lianne C., Morgan, Anthony J., Höglinger, Doris, Tatituri, Raju Venkata V., Clark, Simon, Williams, Ian M., Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S., Besra, Gurdyal S., Russell, David G., Brenner, Michael B., Sim, Edith and Platt, Frances M. 2017. Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway. Wellcome Open Research 1 , 18. 10.12688/wellcomeopenres.10036.2
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Lloyd-Evans, Emyr and Haslett, Luke 2016. The lysosomal storage disease continuum with ageing-related neurodegenerative disease. Ageing Research Reviews 32 , pp. 104-121. 10.1016/j.arr.2016.07.005

Lloyd-Evans, Emyr 2016. On the move, lysosomal CAX drives Ca2+ transport and motility. Journal of cell biology 212 (7) , pp. 755-757. 10.1083/jcb.201603037
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Oswald, Matthew C. W., West, Ryan J. H., Lloyd-Evans, Emyr and Sweeney, Sean T. 2015. Identification of dietary alanine toxicity and trafficking dysfunction in a Drosophila model of hereditary sensory and autonomic neuropathy type 1. Human Molecular Genetics 24 (24) , pp. 6899-6909. 10.1093/hmg/ddv390
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Lee, Ju-Hyun, McBrayer, Mary Kate, Wolfe, Devin M., Haslett, Luke, Kumar, Asok, Sato, Yutaka, Lie, Pearl P.Y., Mohan, Panaiyur, Coffey, Erin E., Kompella, Uday, Mitchell, Claire H., Lloyd-Evans, Emyr and Nixon, Ralph A. 2015. Presenilin 1 maintains Lysosomal Ca2+ homeostasis via TRPML1 by regulating vATPase-mediated lysosome acidification. Cell Reports 12 (9) , pp. 1430-1444. 10.1016/j.celrep.2015.07.050
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Chandrachud, Uma, Walker, Mathew W., Simas, Alexandra M., Heetveld, Sasja, Petcherski, Anton, Klein, Madeleine, Oh, Hyejin, Wolf, Pavlina, Zhao, Wen-Ning, Norton, Stephanie, Haggarty, Stephen J., Lloyd-Evans, Emyr and Cotman, Susan L. 2015. Unbiased cell-based screening in a neuronal cell model of Batten Disease highlights an interaction between Ca2+Homeostasis, autophagy, and CLN3 protein function. Journal of Biological Chemistry 290 (23) , 14361-14380.. 10.1074/jbc.M114.621706

Waller-Evans, Helen and Lloyd-Evans, Emyr 2015. Regulation of TRPML1 function. Biochemical Society Transactions 43 (3) , pp. 442-446. 10.1042/BST20140311

Walker, Mathew W. and Lloyd-Evans, Emyr 2015. A rapid method for the preparation of ultrapure, functional lysosomes using functionalized superparamagnetic iron oxide nanoparticles. Methods in Cell Biology 126 , pp. 21-43. 10.1016/bs.mcb.2014.10.019

Platt, Frances M., Wassif, Christopher, Colaco, Alexandria, Dardis, Andrea, Lloyd-Evans, Emyr, Bembi, Bruno and Porter, Forbes D. 2014. Disorders of cholesterol metabolism and their unanticipated convergent mechanisms of disease. Annual Review of Genomics and Human Genetics 15 (1) , pp. 173-194. 10.1146/annurev-genom-091212-153412

Morgan, Anthony J., Platt, Frances M., Lloyd‑Evans, Emyr and Galione, Antony 2011. Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease. Biochemical Journal 439 (3) , pp. 349-374. 10.1042/BJ20110949

Lloyd-Evans, Emyr and Platt, Frances M. 2011. Lysosomal Ca2+ homeostasis: Role in pathogenesis of lysosomal storage diseases. Cell Calcium 50 (2) , pp. 200-205. 10.1016/j.ceca.2011.03.010

Lloyd-Evans, Emyr, Waller-Evans, Helen, Peterneva, Ksenia and Platt, Frances M. 2010. Endolysosomal calcium regulation and disease. Biochemical Society Transactions 38 (6) , pp. 1458-1464. 10.1042/BST0381458

Lloyd-Evans, Emyr and Platt, Frances M. 2010. Lipids on trial: The search for the offending metabolite in Niemann-Pick type C disease. Traffic 11 (4) , pp. 419-428. 10.1111/j.1600-0854.2010.01032.x

Ruas, Margarida, Rietdorf, Katja, Arredouani, Abdelilah, Davis, Lianne, Lloyd-Evans, Emyr, Koegel, Heidi, Funnell, Timothy, Morgan, Anthony John, Ward, John, Watanabe, Keiko, Cheng, Xiaotong, Churchill, Grant, Zhu, Michael, Platt, Frances, Wessel, Gary, Parrington, John and Galione, Antony 2010. Purified TPC isoforms form NAADP receptors with distinct roles for Ca2+ signaling and endolysosomal trafficking. Current Biology 20 (8) , pp. 703-709. 10.1016/j.cub.2010.02.049

Lloyd-Evans, Emyr, Morgan, Anthony J., He, Xingxuan, Smith, David A., Elliot-Smith, Elena, Sillence, Daniel J., Churchill, Grant C., Schuchman, Edward H., Galione, Antony and Platt, Frances M. 2008. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium. Nature Medicine 14 (11) , pp. 1247-1255. 10.1038/nm.1876

Elliot-Smith, Elena, Speak, Anneliese, Lloyd-Evans, Emyr, Smith, David A., Spoel, Aarnoud C. van der, Jeyakumar, Mylvaganam, Butters, Terry, Dwek, Raymond, d'Azzo, Alessandra and Platt, Frances 2008. Beneficial effects of substrate reduction therapy in a mouse model of GM1 gangliosidosis. Molecular Genetics and Metabolism 94 (2) , pp. 204-211. 10.1016/j.ymgme.2008.02.005

Pelled, Dori, Trajkovic-Bodennec, Selena, Lloyd-Evans, Emyr, Sidransky, Ellen, Schiffmann, Raphael and Futerman, Anthony H. 2005. Enhanced calcium release in the acute neuronopathic form of Gaucher disease. Neurobiology of Disease 18 (1) , pp. 83-88. 10.1016/j.nbd.2004.09.004

Vruchte, D. T., Lloyd-Evans, Emyr, Veldman, R. J., Neville, D. C. A., Dwek, R. A., Platt, F. M., van Blitterswijk, W. J. and Sillence, D. J. 2004. Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport. Journal of Biological Chemistry 279 (25) , pp. 26167-26175. 10.1074/jbc.M311591200

Lachmann, Robin H., te Vruchte, Danielle, Lloyd-Evans, Emyr, Reinkensmeier, Gabriele, Sillence, Daniel J., Fernandez-Guillen, Luisa, Dwek, Raymond A., Butters, Terry D., Cox, Timothy M. and Platt, Frances M. 2004. Treatment with miglustat reverses the lipid-trafficking defect in Niemann–Pick disease type C. Neurobiology of Disease 16 (3) , pp. 654-658. 10.1016/j.nbd.2004.05.002

Lloyd-Evans, Emyr, Pelled, D., Riebeling, C., Bodennec, J., de-Morgan, A., Waller, H., Schiffmann, R. and Futerman, A. H. 2003. Glucosylceramide and glucosylsphingosine modulate calcium mobilization from brain microsomes via different mechanisms. Journal of Biological Chemistry 278 (26) , pp. 23594-23599. 10.1074/jbc.M300212200

Lloyd-Evans, Emyr, Pelled, Dori, Riebeling, Christian and Futerman, Anthony H. 2003. Lyso-glycosphingolipids mobilize calcium from brain microsomes via multiple mechanisms. Biochemical Journal 375 (3) , pp. 561-565. 10.1042/BJ20030613

Pelled, D., Lloyd-Evans, Emyr, Riebeling, C., Jeyakumar, M., Platt, F. M. and Futerman, A. H. 2003. Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-Butyldeoxynojirimycin. Journal of Biological Chemistry 278 (32) , pp. 29496-29501. 10.1074/jbc.M302964200

This list was generated on Wed Nov 13 05:21:22 2019 GMT.