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Number of items: 49.

Luukkonen, Panu K., Nick, Auli, Hölttä-Vuori, Maarit, Thiele, Christoph, Isokuortti, Elina, Lallukka-Brück, Susanna, Zhou, You, Hakkarainen, Antti, Lundbom, Nina, Peltonen, Markku, Orho-Melander, Marju, Oresic, Matej, Hyötyläinen, Tuulia, Hodson, Leanne, Ikonen, Elina and Yki-Järvinen, Hannele 2019. Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids. JCI Insight 4 (16) , e127902. 10.1172/jci.insight.127902

Liu, Zihao, Zhou, You, Liang, Gehao, Ling, Yun, Tan, Weige, Tan, Luyuan, Andrews, Robert, Zhong, Wenjing, Zhang, Xuanxuan, Song, Erwei and Gong, Chang 2019. Circular RNA hsa_circ_001783 regulates breast cancer progression via sponging miR-200c-3p. Cell Death and Disease 10 (2) , 55. 10.1038/s41419-018-1287-1

Kentala, Henriikka, Koponen, Annika, Vihinen, Helena, Pirhonen, Juho, Pirhonen, Juho, Liebisch, Gerhard, Pataj, Zoltan, Kivelä, Annukka, Li, Shiqian, Karhinen, Leena, Jääskeläinen, Eeva, Andrews, Robert, Meriläinen, Leena, Matysik, Silke, Ikonen, Elina, Zhou, You, Jokitalo, Eija and Olkkonen, Vesa M. 2018. OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism. Cellular and Molecular Life Sciences 75 (21) , pp. 4041-4057.

Luukkonen, Panu K., Sädevirta, Sanja, Zhou, You, Kayser, Brandon, Ali, Ashfaq, Ahonen, Linda, Lallukka, Susanna, Pelloux, Veronique, Gaggini, Melania, Jian, Ching, Hakkarainen, Antti, Lundbom, Nina, Gylling, Helena, Salonen, Anne, Oresic, Matej, Hyotylainen, Tuulia, Orho-Melander, Marju, Rissanen, Aila, Gastaldelli, Amalia, Clement, Karine, Hodson, Leanne and Yki-Jarvinen, Hannele 2018. Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars. Diabetes Care 41 (8) , pp. 1732-1739. 10.2337/dc18-0071

Hua, Bian, Hakkarainen, Antti, Zhou, You, Lundbom, Nina and Yki-Järvinen, Hannele 2018. Fat accumulates preferentially in the right rather than the left liver lobe in non-diabetic subjects. Digestive and Liver Disease 50 (2) , pp. 168-174. 10.1016/j.dld.2017.08.030

Aldrovandi, Maceler, Banthiya, Swathi, Meckelmann, Sven, Zhou, You, Heydeck, Dagmar, O'Donnell, Valerie B. and Kuhn, Hartmut 2018. Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863 (2) , pp. 152-164. 10.1016/j.bbalip.2017.11.005

Kentala, Henriikka, Koponen, Annika, Kivelä, Annukka M., Andrews, Robert, Li, ChunHei, Zhou, You and Olkkonen, Vesa M. 2018. Analysis of ORP2 knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. The FASEB Journal 10.1096/fj.201700604R

Liu, Xijiao, Jiang, Hanyu, Chen, Jie, Zhou, You, Huang, Zixing and Song, Bin 2017. Gadoxetic acid-enhanced MRI outperformed MDCT in diagnosing small hepatocellular carcinoma: A meta-analysis. Liver Transplantation 23 (12) , pp. 1505-1518. 10.1002/lt.24867

Lallukka, Susanna, Sädevirta, Sanja, Kallio, Markus T., Luukkonen, Panu K., Zhou, You, Hakkarainen, Antti, Lundbom, Nina, Orho-Melander, Marju and Yki-Järvinen, Hannele 2017. Predictors of liver fat and stiffness in non-alcoholic fatty liver disease (NAFLD) - an 11-Year prospective study. Scientific Reports 7 (1) , 14561. 10.1038/s41598-017-14706-0

Isokuortti, Elina, Zhou, You, Peltonen, Markku, Bugianesi, Elisabetta, Clement, Karine, Bonnefont-Rousselot, Dominique, Lacorte, Jean-Marc, Gastaldelli, Amalia, Schuppan, Detlef, Schattenberg, Jörn M., Hakkarainen, Antti, Lundbom, Nina, Jousilahti, Pekka, Männistö, Satu, Keinänen-Kiukaanniemi, Sirkka, Saltevo, Juha, Anstee, Quentin M. and Yki-Järvinen, Hannele 2017. Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study. Diabetologia 60 (10) , pp. 1873-1882. 10.1007/s00125-017-4340-1

Mysore, Raghavendra, Liebisch, Gerhard, Zhou, You, Olkkonen, Vesa M. and Nidhina Haridas, P.A. 2017. Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition. Chemistry and Physics of Lipids 207 (B) , pp. 246-252. 10.1016/j.chemphyslip.2017.05.002

Luukkonen, Panu K., Zhou, You, Nidhina Haridas, P.A., Dwivedi, Om P., Hyötyläinen, Tuulia, Ali, Ashfaq, Juuti, Anne, Leivonen, Marja, Tukiainen, Taru, Ahonen, Linda, Scott, Emma, Palmer, Jeremy M., Arola, Johanna, Orho-Melander, Marju, Vikman, Petter, Anstee, Quentin M., Olkkonen, Vesa M., Oresic, Matej, Groop, Leif and Yki-Järvinen, Hannele 2017. Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD. Journal of Hepatology 67 (1) , pp. 128-136. 10.1016/j.jhep.2017.02.014

Kara, Bülent, Köroğlu, Çiğdem, Peltonen, Karita, Steinberg, Ruchama C, Maras Genç, Hülya, Hölttä-Vuori, Maarit, Güven, Ayse, Kanerva, Kristiina, Kotil, Tugba, Solakoğlu, Seyhun, Zhou, You, Olkkonen, Vesa M, Ikonen, Elina, Laiho, Marikki and Tolun, Aslihan 2017. Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A. European Journal of Human Genetics 25 (3) , pp. 315-323. 10.1038/ejhg.2016.183

Lallukka, S., Luukkonen, P. K., Zhou, You, Petäjä, E. M., Leivonen, M., Juuti, A., Hakkarainen, A., Orho-Melander, M., Lundbom, N., Olkkonen, V. M., Lassila, R. and Yki-Järvinen, H. 2017. Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans. Thrombosis and Haemostasis 2017 (2) , pp. 207-428. 10.1160/TH16-09-0716

Luukkonen, Panu K., Zhou, You, Hyötyläinen, Tuulia, Leivonen, Marja, Arola, Johanna, Orho-Melander, Marju, Ore?i?, Matej and Yki-Järvinen, Hannele 2016. The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans. Journal of Hepatology 65 (6) , pp. 1263-1265. 10.1016/j.jhep.2016.07.045

Hu, Bang-li, Shi, Cheng, Lei, Rong-e, Lu, Dong-hong, Luo, Wei, Qin, Shan-yu, Zhou, You and Jiang, Hai-xing 2016. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin. Scientific Reports 6 , 36436. 10.1038/srep36436

Zhou, You, Oresic, Matej, Leivonen, Marja, Gopalacharyulu, Peddinti, Hyysalo, Jenni, Arola, Johanna, Verrijken, An, Francque, Sven, Van Gaal, Luc, Hyötyläinen, Tuulia and Yki-Järvinen, Hannele 2016. Non-invasive detection of non-alcoholic Steatohepatitis using clinical markers and circulating levels of lipids and metabolites. Clinical Gastroenterology and Hepatology 14 (10) , pp. 1463-1472. 10.1016/j.cgh.2016.05.046

Petäjä, E.M., Zhou, You, Peltonen, M., Jouslahti, P., Männistö, S., Keinänen-Kiukaanniemi, S., Saltevo, J. and Yki-Järvinen, H. 2016. Determination of a Normal value for HOMA-IR and cut-off Value for Non-Alcoholic Fatty Liver Disease. Journal of Hepatology 64 (2) , S481. 10.1016/S0168-8278(16)00817-5

Xia, Ming-Feng, Yki-Järvinen, Hannele, Bian, Hua, Lin, Huan-Dong, Yan, Hong-Mei, Chang, Xin-Xia, Zhou, You and Gao, Xin 2016. Influence of ethnicity on the accuracy of non-invasive scores predicting non-alcoholic fatty liver disease. PLoS ONE 11 (8) , e0160526. 10.1371/journal.pone.0160526

Luukkonen, Panu K., Zhou, You, Sädevirta, Sanja, Leivonen, Marja, Arola, Johanna, Orešič, Matej, Hyötyläinen, Tuulia and Yki-Järvinen, Hannele 2016. Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease. Journal of Hepatology 64 (5) , pp. 1167-1175. 10.1016/j.jhep.2016.01.002

Petäjä, Elina M., Zhou, You, Havana, Marika, Hakkarainen, Antti, Lundbom, Nina, Ihalainen, Jarkko and Yki-Järvinen, Hannele 2016. Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD. Scientific Reports 6 , 24740. 10.1038/srep24740

Mysore, Raghavendra, Zhou, You, Sädevirta, Sanja, Savolainen-Peltonen, Hanna, Nidhina Haridas, P.A., Soronen, Jarkko, Leivonen, Marja, Sarin, Antti-Pekka, Fischer-Posovszky, Pamela, Wabitsch, Martin, Yki-Järvinen, Hannele and Olkkonen, Vesa M. 2016. MicroRNA-192* impairs adipocyte triglyceride storage. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1861 (4) , pp. 342-351. 10.1016/j.bbalip.2015.12.019

Soronen, Jarkko, Yki- Järvinen, Hannele, Zhou, You, Sädevirta, Sanja, Sarin, Antti-Pekka, Leivonen, Marja, Sevastianova, Ksenia, Perttilä, Julia, Laurila, Pirkka?Pekka, Sigruener, Alexander, Schmitz, Gerd and Olkkonen, Vesa M. 2016. Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease. Physiological Reports 4 (1) , e12661. 10.14814/phy2.12661

Qin, Shan-yu, Lu, Dong-hong, Guo, Xiao-yun, Luo, Wei, Hu, Bang-li, Huang, Xiao-li, Chen, Mei, Wang, Jia-xu, Ma, Shi-Jia, Yang, Xian-wen, Jiang, Hai-xing and Zhou, You 2016. A deleterious role for Th9/IL-9 in hepatic fibrogenesis. Scientific Reports 6 , 18694. 10.1038/srep18694

Hu, Bangli, Luo, Wei, Hu, Rui-Ting, Zhou, You, Qin, Shan-Yu and Jiang, Hai-Xing 2015. Meta-analysis of prognostic and clinical significance of CD44v6 in esophageal cancer. Medicine 94 (31) , e1238. 10.1097/MD.0000000000001238

Zhou, You, Llauradó, Gemma, Oresic, Matej, Hyötyläinen, Tuulia, Orho-Melander, Marju and Yki-Järvinen, Hannele 2015. Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2. Journal of Hepatology 62 (3) , pp. 657-663. 10.1016/j.jhep.2014.10.010

Weber-Boyvat, Marion, Kentala, Henriikka, Lilja, Johanna, Vihervaara, Terhi, Hanninen, Raisa, Zhou, You, Peränen, Johan, Nyman, Tuula A., Ivaska, Johanna and Olkkonen, Vesa M. 2015. OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity. Experimental Cell Research 331 (2) , pp. 278-291. 10.1016/j.yexcr.2014.10.019

Wei, Bingbing, Jin, Wei, Ruan, Jun, Xu, Zhuoqun, Zhou, You, Liang, Jiabei, Cheng, Huan, Jin, Ke, Huang, Xing, Lu, Peng and Hu, Qiang 2015. Cripto-1 expression and its prognostic value in human bladder cancer patients. Tumor Biology 36 (2) , pp. 1105-1113. 10.1007/s13277-014-2695-1

Bian, Hua, Hakkarainen, Antti, Zhou, You, Lundbom, Nina, Olkkonen, Vesa M and Yki-Järvinen, Hannele 2015. Impact of non-alcoholic fatty liver disease on liver volume in humans. Hepatology Research 45 (2) , pp. 210-219. 10.1111/hepr.12338

Lu, Jie-fu, Zhou, You, Huang, Gui-hua, Jiang, Hai-xing, Hu, Bang-li and Qin, Shan-yu 2014. Association of ADIPOQ polymorphisms with obesity risk: a meta-analysis. Human Immunology 75 (10) , pp. 1062-1068. 10.1016/j.humimm.2014.09.004

Qin, Shan-yu, Zhou, You, Li, Ping and Jiang, Hai-xing 2014. Diagnostic efficacy of cell block immunohistochemistry, smear cytology, and liquid-based cytology in endoscopic ultrasound-guided fine-needle aspiration of pancreatic lesions: a single-institution experience. PLoS ONE 9 (9) , e108762. 10.1371/journal.pone.0108762

Zhou, You, Wohlfahrt, Gerd, Paavola, Jere and Olkkonen, Vesa M. 2014. A vertebrate model for the study of lipid binding/transfer protein function: Conservation of OSBP-related proteins between zebrafish and human. Biochemical and Biophysical Research Communications 446 (3) , pp. 675-680. 10.1016/j.bbrc.2013.12.002

Hyysalo, Jenni, Männistö, Ville T., Zhou, You, Arola, Johanna, Kärjä, Vesa, Leivonen, Marja, Juuti, Anne, Jaser, Nabil, Lallukka, Susanna, Käkelä, Pirjo, Venesmaa, Sari, Simonen, Marko, Saltevo, Juha, Moilanen, Leena, Korpi-Hyövalti, Eeva, Keinänen-Kiukaanniemi, Sirkka, Oksa, Heikki, Orho-Melander, Marju, Valenti, Luca, Fargion, Silvia, Pihlajamäki, Jussi, Peltonen, Markku and Yki-Järvinen, Hannele 2014. A population-based study on the prevalence of NASH using scores validated against liver histology. Journal of Hepatology 60 (4) , pp. 839-846. 10.1016/j.jhep.2013.12.009

Ruhanen, H., Perttila, J., Holtta-Vuori, M., Zhou, You, Yki-Jarvinen, H., Ikonen, E., Kakela, R. and Olkkonen, V. M. 2014. PNPLA3 mediates hepatocyte triacylglycerol remodeling. Journal of Lipid Research 55 (4) , pp. 739-746. 10.1194/jlr.M046607

Qin, Shanyu, Ma, Shijia, Huang, Xiaoli, Lu, Donghong, Zhou, You and Jiang, Haixing 2014. Th22 cells are associated with hepatocellular carcinoma development and progression. Chinese Journal of Cancer Research 26 (2) , pp. 135-141. 10.3978/j.issn.1000-9604.2014.02.14

Zhong, Wenbin, Zhou, You, Li, Jiwei, Mysore, Raghavendra, Luo, Wei, Li, Shiqian, Chang, Mau-Sun, Olkkonen, Vesa M. and Yan, Daoguang 2014. OSBP-related protein 8 (ORP8) interacts with Homo sapiens sperm associated antigen 5 (SPAG5) and mediates oxysterol interference of HepG2 cell cycle. Experimental Cell Research 322 (2) , pp. 227-235. 10.1016/j.yexcr.2014.01.002

Wang, Junli, Nong, Legen, Wei, Yesheng, Qin, Shanyu, Zhou, You and Tang, Yujin 2014. Association of osteopontin polymorphisms with nasopharyngeal carcinoma risk. Human Immunology 75 (1) , pp. 76-80. 10.1016/j.humimm.2013.09.014

Qin, Shan-Yu, Jiang, Hai-Xing, Lu, Dong-Hong and Zhou, You 2013. Association of interleukin-10 polymorphisms with risk of irritable bowel syndrome: A meta-analysis. World Journal of Gastroenterology 19 (48) , pp. 9472-9480. 10.3748/wjg.v19.i48.9472

Wang, Junli, Nong, Legen, Wei, Yesheng, Qin, Shanyu, Zhou, You and Tang, Yujin 2013. Association of interleukin-12 polymorphisms and serum IL-12p40 levels with osteosarcoma risk. DNA and Cell Biology 32 (10) , pp. 605-610. 10.1089/dna.2013.2098

Qin, Shan-yu, Liu, Jie, Jiang, Hai-xing, Hu, Bang-li, Zhou, You and Olkkonen, Vesa M. 2013. Association between baseline lipoprotein (a) levels and restenosis after coronary stenting: meta-analysis of 9 cohort studies. Atherosclerosis 227 (2) , pp. 360-366. 10.1016/j.atherosclerosis.2013.01.014

Ruan, Jun, Wei, Bingbing, Xu, Zhuoqun, Yang, Shudong, Zhou, You, Yu, Minhong, Liang, Jiabei, Jin, Ke, Huang, Xing, Lu, Peng and Cheng, Huan 2013. Predictive value of Sox2 expression in transurethral resection specimens in patients with T1 bladder cancer. Medical Oncology 30 (1) , 445. 10.1007/s12032-012-0445-z

Li, Fei, Chen, Ding-nan, He, Cheng-wu, Zhou, You, Olkkonen, Vesa M., He, Nan, Chen, Wei, Wan, Pei, Chen, San-san, Zhu, Yong-tong, Lan, Kai-jian and Tan, Wan-long 2012. Identification of urinary Gc-globulin as a novel biomarker for bladder cancer by two-dimensional fluorescent differential gel electrophoresis (2D-DIGE). Journal of Proteomics 77 , pp. 225-236. 10.1016/j.jprot.2012.09.002

Zhou, You, Robciuc, Marius R., Wabitsch, Martin, Juuti, Anne, Leivonen, Marja, Ehnholm, Christian, Yki-Järvinen, Hannele and Olkkonen, Vesa M. 2012. OSBP-related proteins (ORPs) in human adipose depots and cultured adipocytes: Evidence for impacts on the adipocyte phenotype. PLoS ONE 7 (9) , e45352. 10.1371/journal.pone.0045352

Olkkonen, Vesa M., Zhou, You, Yan, Daoguang and Vihervaara, Terhi 2012. Oxysterol-binding proteins-emerging roles in cell regulation. European Journal of Lipid Science and Technology 114 (6) , pp. 634-643. 10.1002/ejlt.201200044

Li, Fei, An, Sheng-li, Zhou, You, Liang, Zhong-kun, Jiao, Zhan-jiang, Jing, Yu-ming, Wan, Pei, Shi, Xiao-jun and Tan, Wan-long 2011. Milk and dairy consumption and risk of bladder cancer: a Meta-analysis. Urology 78 (6) , pp. 1298-1305. 10.1016/j.urology.2011.09.002

Zhong, Wenbin, Zhou, You, Li, Shiqian, Zhou, Tianhong, Ma, Hongling, Wei, Kunde, Li, Hongye, Olkkonen, Vesa M. and Yan, Daoguang 2011. OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability. Experimental Cell Research 317 (16) , pp. 2353-2363. 10.1016/j.yexcr.2011.05.028

Wei, B., Zhou, You, Xu, Z., Ruan, J., Zhu, M., Jin, K., Zhou, D., Hu, Q., Wang, Q., Wang, Z. and Yan, Z. 2011. XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-analysis. Prostate Cancer and Prostatic Diseases 14 (3) , pp. 225-231. 10.1038/pcan.2011.26

Zhou, You, Li, Shiqian, Mäyränpää, Mikko I., Zhong, Wenbin, Bäck, Nils, Yan, Daoguang and Olkkonen, Vesa M. 2010. OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface. Experimental Cell Research 316 (19) , pp. 3304-3316. 10.1016/j.yexcr.2010.06.008

Wu, Xiaoyun, Zhou, You, Zhang, Ke, Liu, Qingzhen and Guo, Deyin 2008. Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B. FEBS Letters 582 (15) , pp. 2155-2160. 10.1016/j.febslet.2008.05.033

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