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Number of items: 45.

Prada, Maria Llamazares, Espinet, Elisa, Mijosek, Vedrana, Schwartz, Uwe, Lutsik, Pavlo, Tamas, Raluca, Richter, Mandy, Behrendt, Annika, Pohl, Stephanie T., Benz, Naja P., Muley, Thomas, Warth, Arne, Heusel, Claus Peter, Winter, Hauke, Landry, Jonathan J.M., Herth, Felix J.F., Mertens, Tinne C.J., Karmouty-Quintana, Harry, Koch, Ina, Benes, Vladimir, Korbel, Jan O., Waszak, Sebastian M., Trumpp, Andreas, Wyatt, David M., Stahl, Heiko F., Plass, Christoph and Jurkowska, Renata Z. 2021. Versatile workflow for cell-type resolved transcriptional and epigenetic profiles from cryopreserved human lung. JCI Insight 6 (5) , e140443. 10.1172/jci.insight.140443
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Al-Amri, Mohammad and Jurkowska, Renata, eds. 2020. Proceedings of Cardiff Institute for Tissue Engineering & Repair annual scientific meeting (CITER ASM 2020). Cardiff: CITER & Cardiff University.
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Ogger, Patricia P., Silva, Johnatas Dutra, Aghapour, Mahyar, Persson, Irma Mahmutovic, Tulen, Christy, Jurkowska, Renata and Ubags, Niki D. 2020. Early Career Members at the ERS Lung Science Conference 2020: metabolic alterations in lung ageing and disease. Breathe 16 (3) , 200063. 10.1183/20734735.0063-2020
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Gao, Linfeng, Emperle, Max, Guo, Yiran, Grimm, Sara A., Ren, Wendan, Adam, Sabrina, Uryu, Hidetaka, Zhang, Zhi-Min, Chen, Dongliang, Yin, Jiekai, Dukatz, Michael, Anteneh, Hiwot, Jurkowska, Renata Z., Lu, Jiuwei, Wang, Yinsheng, Bashtrykov, Pavel, Wade, Paul A., Wang, Gang Greg, Jeltsch, Albert and Song, Jkui 2020. Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nature Communications 11 , 3355. 10.1038/s41467-020-17109-4
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Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z., Abdollahi, Amir, Zenke, Frank T., Neumann, Beate and Mardin, Balca R. 2020. A solid‐phase transfection platform for arrayed CRISPR screens [Corrigendum]. Molecular Systems Biology 16 (6) 10.15252/msb.209611
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Serçin, Özdemirhan, Reither, Sabine, Roidos, Paris, Ballin, Nadja, Palikyras, Spyridon, Baginska, Anna, Rein, Katrin, Llamazares, Maria, Halavatyi, Aliaksandr, Winter, Hauke, Muley, Thomas, Jurkowska, Renata Z., Abdollahi, Amir, Zenke, Frank T., Neumann, Beate and Mardin, Balca R. 2019. A solid-phase transfection platform for arrayed CRISPR screens. Molecular Systems Biology 15 (12) , e8983. 10.15252/msb.20198983
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Rajavelu, Arumugam, Lungu, Cristiana, Emperle, Max, Dukatz, Michael, Bröhm, Alexander, Broche, Julian, Hanelt, Ines, Parsa, Edris, Schiffers, Sarah, Karnik, Rahul, Meissner, Alexander, Carell, Thomas, Rathert, Philipp, Jurkowska, Renata Z. and Jeltsch, Albert 2018. Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research 46 (17) , 9044–9056. 10.1093/nar/gky715
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Emperle, Max, Dukatz, Michael, Kunert, Stefan, Holzer, Katharina, Rajavelu, Arumugam, Jurkowska, Renata Z. and Jeltsch, Albert 2018. The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes. Scientific Reports 8 (1) , -. 10.1038/s41598-018-31635-8
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Emperle, Max, Rajavelu, Arumugam, Kunert, Stefan, Arimondo, Paola B., Reinhardt, Richard, Jurkowska, Renata Z. and Jeltsch, Albert 2018. The DNMT3A R882H mutant displays altered flanking sequence preferences. Nucleic Acids Research 46 (6) , pp. 3130-3139. 10.1093/nar/gky168
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Ravichandran, M., Jurkowska, Renata and Jurkowski, Tomasz 2018. Target specificity of mammalian DNA methylation and demethylation machinery. Organic and Biomolecular Chemistry (9) , pp. 1419-1435. 10.1039/C7OB02574B
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Jurkowska, Renata Z., Qin, Su, Kungulovski, Goran, Tempel, Wolfram, Liu, Yanli, Bashtrykov, Pavel, Stiefelmaier, Judith, Jurkowski, Tomasz P., Kudithipudi, Srikanth, Weirich, Sara, Tamas, Raluca, Wu, Hong, Dombrovski, Ludmila, Loppnau, Peter, Reinhardt, Richard, Min, Jinrong and Jeltsch, Albert 2017. H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nature Communications 8 , 2057. 10.1038/s41467-017-02259-9
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Stepper, Peter, Kungulovski, Goran, Jurkowska, Renata Z., Chandra, Tamir, Krueger, Felix, Reinhardt, Richard, Reik, Wolf, Jeltsch, Albert and Jurkowski, Tomasz P. 2017. Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase. Nucleic Acids Research 45 (4) , pp. 1703-1713. 10.1093/nar/gkw1112
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Jurkowska, Renata Z. and Jeltsch, Albert 2016. Mechanisms and biological roles of DNA methyltransferases and DNA methylation: From past achievements to future challenges. Advances in Experimental Medicine and Biology 945 , pp. 1-17. 10.1007/978-3-319-43624-1_1

Jurkowska, Renata Z. and Jeltsch, Albert 2016. Enzymology of mammalian DNA methyltransferases. Advances in Experimental Medicine and Biology 945 , pp. 87-122. 10.1007/978-3-319-43624-1_5

Jeltsch, Albert and Jurkowska, Renata Z. 2016. Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm. Nucleic Acids Research 44 (18) , pp. 8556-8575. 10.1093/nar/gkw723
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Lungu, Cristiana, Muegge, Kathrin, Jeltsch, Albert and Jurkowska, Renata Z. 2015. An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric Heterochromatin. Journal of Molecular Biology 427 (10) , pp. 1903-1915. 10.1016/j.jmb.2015.03.014

Kungulovski, Goran, Kycia, Ina, Tamas, Raluca, Jurkowska, Renata Z., Kudithipudi, Srikanth, Henry, Chisato, Reinhardt, Richard, Labhart, Paul and Jeltsch, Albert 2014. Application of histone modification-specific interaction domains as an alternative to antibodies. Genome Research 24 (11) , pp. 1842-1853. 10.1101/gr.170985.113
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Emperle, Max, Rajavelu, Arumugam, Reinhardt, Richard, Jurkowska, Renata Z. and Jeltsch, Albert 2014. Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase. Journal of Biological Chemistry 289 (43) , pp. 29602-29613. 10.1074/jbc.M114.572032
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Jeltsch, Albert and Jurkowska, Renata Z. 2014. New concepts in DNA methylation. Trends in Biochemical Sciences 39 (7) , pp. 310-318. 10.1016/j.tibs.2014.05.002

Bashtrykov, Pavel, Jankevicius, Gytis, Jurkowska, Renata Z., Ragozin, Sergey and Jeltsch, Albert 2014. The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism. Journal of Biological Chemistry 289 (7) , pp. 4106-4116. 10.1074/jbc.M113.528893
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Jurkowska, Renata Z. and Jeltsch, Albert 2013. Genomic imprinting-the struggle of the genders at the molecular level. Angewandte Chemie International Edition 52 (51) , pp. 13524-13536. 10.1002/anie.201307005

Jeltsch, Albert and Jurkowska, Renata Z. 2013. Multimerization of the Dnmt3a DNA methyltransferase and its functional implications. Progress in Molecular Biology and Translational Science 117 , pp. 445-464. 10.1016/B978-0-12-386931-9.00016-7

Siddique, Abu Nasar, Nunna, Suneetha, Rajavelu, Arumugam, Zhang, Yingying, Jurkowska, Renata Z., Reinhardt, Richard, Rots, Marianne G., Ragozin, Sergey, Jurkowski, Tomasz P. and Jeltsch, Albert 2012. Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity. Journal of Molecular Biology 425 (3) , 479—491. 10.1016/j.jmb.2012.11.038

Bashtrykov, Pavel, Jankevicius, Gytis, Smarandache, Anita, Jurkowska, Renata Z., Ragozin, Sergey and Jeltsch, Albert 2012. Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain. Chemistry and Biology 19 (5) , pp. 572-578. 10.1016/j.chembiol.2012.03.010

Halby, Ludovic, Champion, Christine, Sénamaud-Beaufort, Catherine, Ajjan, Sophie, Drujon, Thierry, Rajavelu, Arumugam, Ceccaldi, Alexandre, Jurkowska, Renata, Lequin, Olivier, Nelson, William G., Guy, Alain, Jeltsch, Albert, Guianvarc'h, Dominique, Ferroud, Clotilde and Arimondo, Paola B. 2012. Rapid synthesis of new DNMT inhibitors derivatives of procainamide. ChemBioChem 13 (1) , pp. 157-165. 10.1002/cbic.201100522

Jurkowska, Renata Zofia, Jurkowski, Tomasz Piotr and Jeltsch, Albert 2011. Structure and function of mammalian DNA methyltransferases. ChemBioChem 12 (2) , 206—222. 10.1002/cbic.201000195

Jurkowska, Renata Z., Ceccaldi, Alexandre, Zhang, Yingying, Arimondo, Paola B. and Jeltsch, Albert 2011. DNA methyltransferase assays. Epigenetics Protocols, Vol. 791. Methods in Molecular Biology, Humana Press, pp. 157-177. (10.1007/978-1-61779-316-5_13)

Jurkowska, Renata Z., Rajavelu, Arumugam, Anspach, Nils, Urbanke, Claus, Jankevicius, Gytis, Ragozin, Sergey, Nellen, Wolfgang and Jeltsch, Albert 2011. Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules. Journal of Biological Chemistry 286 (27) , pp. 24200-24207. 10.1074/jbc.M111.254987
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Jurkowska, Renata Z., Siddique, Abu Nasar, Jurkowski, Tomasz P. and Jeltsch, Albert 2011. Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase. ChemBioChem 12 (10) , 1589—1594. 10.1002/cbic.201000673

Ceccaldi, Alexandre, Rajavelu, Arumugam, Champion, Christine, Rampon, Christine, Jurkowska, Renata, Jankevicius, Gytis, Sénamaud-Beaufort, Catherine, Ponger, Loïc, Gagey, Nathalie, Dali Ali, Hana, Tost, Jörg, Vriz, Sophie, Ros, Sindu, Dauzonne, Daniel, Jeltsch, Albert, Guianvarc'h, Dominique and Arimondo, Paola B. 2011. C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development. ChemBioChem 12 (9) , pp. 1337-1345. 10.1002/cbic.201100130

Siddique, Abu Nasar, Jurkowska, Renata Z., Jurkowski, Tomasz P. and Jeltsch, Albert 2011. Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue. FEBS Journal 278 (12) , 2055—2063. 10.1111/j.1742-4658.2011.08121.x

Rajavelu, Arumugam, Jurkowska, Renata Z., Fritz, Jürgen and Jeltsch, Albert 2011. Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation. Nucleic Acids Research 40 (2) , 569–580. 10.1093/nar/gkr753
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Champion, Christine, Guianvarc'h, Dominique, Sénamaud-Beaufort, Catherine, Jurkowska, Renata Z., Jeltsch, Albert, Ponger, Loïc, Arimondo, Paola B. and Guieysse-Peugeot, Anne-Laure 2010. Mechanistic insights on the inhibition of C5 DNA methyltransferases by zebularine. PLoS ONE 5 (8) , e12388. 10.1371/journal.pone.0012388
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Dhayalan, Arunkumar, Rajavelu, Arumugam, Rathert, Philipp, Tamas, Raluca, Jurkowska, Renata Z., Ragozin, Sergey and Jeltsch, Albert 2010. The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and Guides DNA methylation. Journal of Biological Chemistry 285 (34) , pp. 26114-26120. 10.1074/jbc.M109.089433
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Zhang, Yingying, Jurkowska, Renata, Soeroes, Szabolcs, Rajavelu, Arumugam, Dhayalan, Arunkumar, Bock, Ina, Rathert, Philipp, Brandt, Ole, Reinhardt, Richard, Fischle, Wolfgang and Jeltsch, Albert 2010. Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Research 38 (13) , 4246–4253. 10.1093/nar/gkq147

Jurkowska, Renata Z. and Jeltsch, Albert 2010. Silencing of gene expression by targeted DNA methylation: concepts and approaches. Engineered Zinc Finger Proteins, Vol. 649. Humana Press, pp. 149-161. (10.1007/978-1-60761-753-2_9)

Jeltsch, Albert and Jurkowska, Renata Z. 2010. DNA methylation. The Chemical Biology of Nucleic Acids, Wiley, pp. 307-301. (10.1002/9780470664001.ch14)

Métivier, Raphaël, Gallais, Rozenn, Tiffoche, Christophe, Le Péron, Christine, Jurkowska, Renata Z., Carmouche, Richard P., Ibberson, David, Barath, Peter, Demay, Florence, Reid, George, Benes, Vladimir, Jeltsch, Albert, Gannon, Frank and Salbert, Gilles 2010. Erratum: Cyclical DNA methylation of a transcriptionally active promoter. Nature 463 (7279) , 384. 10.1038/nature08661

Jurkowska, Renata Z., Anspach, Nils, Urbanke, Claus, Jia, Da, Reinhardt, Richard, Nellen, Wolfgang, Cheng, Xiaodong and Jeltsch, Albert 2008. Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Research 36 (21) , 6656–6663. 10.1093/nar/gkn747
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Rathert, Philipp, Dhayalan, Arunkumar, Murakami, Marie, Zhang, Xing, Tamas, Raluca, Jurkowska, Renata, Komatsu, Yasuhiko, Shinkai, Yoichi, Cheng, Xiaodong and Jeltsch, Albert 2008. Protein lysine methyltransferase G9a acts on non-histone targets. Nature Chemical Biology 4 (6) , 344–346. 10.1038/nchembio.88

Métivier, Raphaël, Gallais, Rozenn, Tiffoche, Christophe, Le Péron, Christine, Jurkowska, Renata Z., Carmouche, Richard P., Ibberson, David, Barath, Peter, Demay, Florence, Reid, George, Benes, Vladimir, Jeltsch, Albert, Gannon, Frank and Salbert, Gilles 2008. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452 (7183) , 45–50. 10.1038/nature06544

Jia, Da, Jurkowska, Renata Z., Zhang, Xing, Jeltsch, Albert and Cheng, Xiaodong 2007. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449 (7159) , 248–251. 10.1038/nature06146

Gallais, Rozenn, Demay, Florence, Barath, Peter, Finot, Laurence, Jurkowska, Renata, Le Guével, Rémy, Gay, Frédérique, Jeltsch, Albert, Métivier, Raphaël and Salbert, Gilles 2007. Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation. Molecular Endocrinology -Baltimore- 21 (9) , 2085–2098. 10.1210/me.2006-0490

Jeltsch, Albert, Jurkowska, Renata Z, Jurkowski, Tomasz P, Liebert, Kirsten, Rathert, Philipp and Schlickenrieder, Martina 2007. Application of DNA methyltransferases in targeted DNA methylation. Applied Microbiology and Biotechnology 75 (6) , 1233—1240. 10.1007/s00253-007-0966-0

Gowher, Humaira, Loutchanwoot, Panida, Vorobjeva, Olga, Handa, Vikas, Jurkowska, Renata Z, Jurkowski, Tomasz P and Jeltsch, Albert 2006. Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase. Journal of Molecular Biology 357 (3) , 928—941. 10.1016/j.jmb.2006.01.035

This list was generated on Sat Apr 10 04:19:54 2021 BST.