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Number of items: 17.

Huang, Juan, Pearson, James A., Peng, Jian, Hu, Youjia, Sha, Sha, Xing, Yanpeng, Huang, Gan, Li, Xia, Hu, Fang, Xie, Zhiguo, Xiao, Yang, Luo, Shuoming, Chao, Chen, Wong, Florence S., Zhou, Zhiguang and Wen, Li 2020. Gut microbial metabolites alter IgA immunity in type 1 diabetes. JCI Insight 5 (10) , e135718. 10.1172/jci.insight.135718
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Pearson, James A., Tai, Ningwen, Ekanayake-Alper, Dilrukshi K., Peng, Jian, Hu, Youjia, Hager, Karl, Compton, Susan, Wong, F. Susan, Smith, Peter C. and Wen, Li 2019. Norovirus changes susceptibility to type 1 diabetes by altering intestinal microbiota and immune cell functions. Frontiers in Immunology 10 , 2654. 10.3389/fimmu.2019.02654
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Pearson, James A., Kakabadse, Dimitri, Davies, Joanne, Peng, Jian, Warden-Smith, Jeremy, Cuff, Simone, Lewis, Mark, Camargo da Rosa, Larissa, Wen, Li and Wong, F. Susan 2019. Altered gut microbiota activate and expand insulin B15-23-Reactive CD8+ T-Cells. Diabetes 68 (5) , pp. 1002-1013. 10.2337/db18-0487
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Liu, Mengju, Peng, Jian, Tai, Ningwen, Pearson, James A., Hu, Changyun, Guo, Junhua, Hou, Lin, Zhao, Hongyu, Wong, F. Susan and Wen, Li 2018. Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes. Diabetologia 61 (11) , pp. 2333-2343. 10.1007/s00125-018-4705-0
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Gülden, Elke, Chao, Chen, Tai, Ningwen, Pearson, James A., Peng, Jian, Majewska-Szczepanik, Monika, Zhou, Zhiguang, Wong, F. Susan and Wen, Li 2018. TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells. Journal of Autoimmunity 93 , pp. 57-65. 10.1016/j.jaut.2018.06.003
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Majewska-Szczepanik, Monika, Kowalczyk, Paulina, Biała, Dominika, Marcińska, Katarzyna, Strzępa, Anna, Woźniak, Dorota, Sura, Piotr, Pearson, James, Wen, Li and Szczepanik, Marian 2018. Cyclophosphamide-modified murine peritoneal macrophages induce CD4+ T contrasuppressor cells that protect contact sensitivity T effector cells from suppression. Pharmacological Reports 70 (4) , pp. 796-803. 10.1016/j.pharep.2018.02.015

Tan, Qiyuan, Tai, Ningwen, Li, Yangyang, Pearson, James, Pennetti, Sean, Zhou, Zhiguang, Wong, Florence and Wen, Li 2018. Activation-induced cytidine deaminase deficiency accelerates autoimmune diabetes in NOD mice. JCI Insight 3 (1) , 95882. 10.1172/jci.insight.95882
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Li, Y. Y., Pearson, J. A., Chao, C., Peng, J., Zhang, X., Zhou, Z., Liu, Y., Wong, Florence Susan and Wen, L. 2017. Nucleotide-binding oligomerization domain-containing protein 2 (Nod2) modulates T1DM susceptibility by gut microbiota. Journal of Autoimmunity 82 , pp. 85-95. 10.1016/j.jaut.2017.05.007
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Thayer, Terri C., Pearson, James A., De Leenheer, Evy, Hanna, Stephanie J., Boldison, Joanne, Davies, Joanne, Tsui, Adrian, Ahmed, Sartaj, Easton, Peter, Siew, Lai Khai, Wen, Li and Wong, F. Susan 2016. Peripheral proinsulin expression controls low-avidity proinsulin-reactive CD8 T Cells in type 1 diabetes. Diabetes 65 (11) , pp. 3429-3439. 10.2337/db15-1649
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Clement, Mathew, Pearson, James, Gras, Stephanie, Van den berg, Hugo, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark, Dockree, Tamsin, McLaren, James, Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil, Burrows, Scott, Price, David, Wong, F. Susan, Peakman, Mark, Skowera, Ania and Wooldridge, Linda 2016. Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports 6 , 35332. 10.1038/srep35332
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Pearson, James A., Thayer, Terri C., McLaren, James E., Ladell, Kristin, De Leenheer, Evy, Phillips, Amy, Davies, Joanne, Kakabadse, Dimitri, Miners, Kelly, Morgan, Peter, Wen, Li, Price, David A. and Wong, Florence Susan 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+T cells. Diabetes 65 (6) , pp. 1679-1689. 10.2337/db15-1498
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Pearson, James A., Wong, F. Susan and Wen, Li 2016. The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes. Journal of Autoimmunity 66 , pp. 76-88. 10.1016/j.jaut.2015.08.019

Pearson, James A. and Wong, Florence Susan 2015. Identification of islet antigen-specific CD8 T cells using MHCI-peptide tetramer reagents in the non obese diabetic (NOD) mouse model of type 1 diabetes. In: Gillespie, Kathleen M. ed. Type-1 Diabetes, Vol. 1433. Methods in Molecular Biology, Springer, pp. 119-125. (10.1007/7651_2015_295)

Ye, Jody, Long, Anna E., Pearson, James A., Taylor, Hazel, Bingley, Polly J., Williams, Alistair J. K. and Gillespie, Kathleen M. 2015. Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes. Diabetologia 58 (10) , pp. 2284-2287. 10.1007/s00125-015-3702-9

Hu, Changyun, Ding, Heyuan, Li, Yangyang, Pearson, James A., Zhang, Xiaojun, Flavell, Richard A., Wong, F. Susan and Wen, Li 2015. NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. Proceedings of the National Academy of Sciences 112 (36) , pp. 11318-11323. 10.1073/pnas.1513509112

Motozono, Chihiro, Pearson, James A., De Leenheer, Evy, Rizkallah, Pierre, Beck, Konrad, Trimby, Andrew, Sewell, Andrew K., Wong, F. Susan and Cole, David K. 2015. Distortion of the major histocompatibility complex class I binding groove to accommodate an insulin-derived 10-Mer peptide. Journal of Biological Chemistry 290 (31) , pp. 18924-18933. 10.1074/jbc.M114.622522
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Pearson, James 2014. Analysis of the repertoire of insulin-reactive CD8+ T cells. PhD Thesis, Cardiff University.
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This list was generated on Mon Aug 3 04:12:29 2020 BST.