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Number of items: 34.

Ang, Daniel A., Carter, Jean-Michel, Deka, Kamalakshi, Tan, Joel H. L., Zhou, Jianbiao, Chen, Qingfeng, Chng, Wee Joo, Harmston, Nathan and Li, Yinghui 2024. Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma. Nature Communications 15 (1) , 2513. 10.1038/s41467-024-46728-4
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Tan, Qian Hui, Otgonbaatar, Agimaa, Kaur, Prameet, Ga, Angelica Faye, Harmston, Nathan P. and Tolwinski, Nicholas S. 2024. The Wnt co-receptor PTK7/Otk and Its Homolog Otk-2 in neurogenesis and patterning. Cells 13 (5) , 365. 10.3390/cells13050365
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Madan, Babita, Wadia, Shawn R., Patnaik, Siddhi, Harmston, Nathan, Tan, Emile, Tan, Iain Bee Huat, Nes, W. David, Petretto, Enrico and Virshup, David M. 2024. The cholesterol biosynthesis enzyme FAXDC2 couples Wnt/β-catenin to RTK/MAPK signaling. The Journal of Clinical Investigation 134 (6) , e171222. 10.1172/JCI171222
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Zhong, Zheng, Harmston, Nathan, Wood, Kris C., Madan, Babita and Virshup, M. 2022. A p300/GATA6 axis determines differentiation and Wnt dependency in pancreatic cancer models. Journal of Clinical Investigation 132 (12) , e156305. 10.1172/JCI156305
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Lusk, Jay B., Chua, Ellora Hui Zhen, Kaur, Prameet, Sung, Isabelle Chiao Han, Lim, Wen Kin, Lam, Vanessa Yuk Man, Harmston, Nathan and Tolwinski, Nicholas S. 2022. A non-canonical Raf function is required for dorsal–ventral patterning during Drosophila embryogenesis. Scientific Reports 12 , 7684. 10.1038/s41598-022-11699-3
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Kaur, Prameet, Otgonbaatar, Agimaa, Ramamoorthy, Anupriya, Chua, Ellora Hui Zhen, Harmston, Nathan, Gruber, Jan and Tolwinski, Nicholas S. 2022. Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan. [Online]. bioRXiv. Available at: https://doi.org/10.1101/2022.04.21.488994
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Chua, Ellora Hui Zhen, Yasar, Samen and Harmston, Nathan 2022. The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong! Biology Open 11 (4) , bio059091. 10.1242/bio.059091
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Kaur, Prameet, Chua, Ellora Hui Zhen, Lim, Wen Kin, Liu, Jiarui, Harmston, Nathan and Tolwinski, Nicholas 2022. Wnt signaling rescues amyloid beta-induced gut stem cell loss. Cells 11 (2) , 281. 10.3390/cells11020281
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Harmston, Nathan, Lim, Stanley Yi Jun, Arqués, Oriel, Palmer, Hector G., Petretto, Enrico, Virshup, David M. and Madan, Babita 2021. Widespread repression of gene expression in cancer by a Wnt/β-Catenin/MAPK pathway. Cancer Research 81 (2) , pp. 464-475. 10.1158/0008-5472.CAN-20-2129

Yu, Jia, Yusoff, Permeen A. Mohamed, Woutersen, Daniëlle T.J., Goh, Pamela, Harmston, Nathan, Smits, Ron, Epstein, David M., Virshup, David M. and Madan, Babita 2020. The functional landscape of patient-derived RNF43 mutations predicts sensitivity to Wnt inhibition. Cancer Research 80 (24) , pp. 5619-5632. 10.1158/0008-5472.CAN-20-0957

Kaur, Amanpreet, Sepramaniam, Sugunavathi, Lim, Jun Yi Stanley, Patnaik, Siddhi, Harmston, Nathan, Lee, May Ann, Petretto, Enrico, Virshup, David M. and Madan, Babita 2020. WNT inhibition creates a BRCA-like state in Wnt-addicted cancer. [Online]. bioRXiv: bioRXiv. Available at: https://doi.org/10.1101/2020.06.17.157024

Yu, Jia, Yuso, Permeen Akhtar Bt Mohamed, Goh, Pamela, Harmston, Nathan, Epstein, David M., Virship, David M. and Madan, Babita 2020. The functional landscape of patient derived RNF43 mutations predicts Wnt inhibitor sensitivity. [Online]. bioRXiv: bioRXiv. Available at: https://doi.org/10.1101/2020.03.25.006999

Yapp, Lynn, Wang, Jiong-Wei, Moreno-Moral, Aida, Chong, Li Yen, Sun, Yi, Harmston, Nathan, Wang, Xiaoyuan, Chong, Suet Yen, Vanezis, Konstantinos, Ohman, Miina K., Wei, Heming, Bunte, Ralph, Gosh, Sujoy, Cook, Stuart, Hovatta, Outi, de Kleijn, Dominique P.V., Petretto, Enrico and Tryggvason, Karl 2020. In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors. Cell Reports 26 (12) , pp. 3231-3245. 10.1016/j.celrep.2019.02.083

Liu, S., Harmston, Nathan, Glazer, Trudy Lee, Wong, Yunka, Zhong, Zheng, Madan, Babita, Virship, David M. and Petretto, Enrico 2020. Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation. [Online]. BioRXiv. Available at: https://doi.org/10.1101/2020.02.09.941005
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Idris, Muhammad, Harmston, Nathan, Petretto, Enrico, Madan, Babita and Virshup, David M. 2019. Broad regulation of gene isoform expression by Wnt signaling in cancer. RNA 25 (12) , pp. 1696-1713. 10.1261/rna.071506.119

Chen, Huimei, Moreno-Moral, Aida, Pesce, Francesco, Devapragash, Nithya, Mancini, Massimiliano, Heng, Ee Ling, Rotival, Maxime, Srivastava, Prashant K., Harmston, Nathan, Shkura, Kirill, Rackham, Owen J.L., Yu, Wei-Ping, Sun, Xi-Ming, Tee, Nicole Gui Zhen, Tan, Elisabeth Li Sa, Barton, Paul J.R., Felkin, Leanne E., Lara-Pezzi, Enrique, Angelini, Gianni, Beltrami, Cristina, Pravenec, Michael, Schafer, Sebastian, Bottolo, Leonardo, Hubner, Norbert, Emanueli, Constanza, Cook, Stuart A. and Petretto, Enrico 2019. WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nature Communications 10 , 3616. 10.1038/s41467-019-11551-9

Bardile, Costanza Ferrari, Garcia-Miralles, Marta, Caron, Nicholas S., Rayan, Nirmala Arul, Langley, Sarah R. ORCID: https://orcid.org/0000-0003-4419-476X, Harmston, Nathan, Rondelli, Ana Maria, Teo, Roy Tang Yi, Waltl, Sabine, Anderson, Lisa M., Bae, Han-Gyu, Jung, Sangyong, Williams, Anna, Prabhakar, Shyam, Petretto, Enrico, Hayden, Michael R. and Pouladi, Mahmoud A. 2019. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America 116 (19) , pp. 9622-9627. 10.1073/pnas.1818042116

Ooi, Jolene, Langley, Sarah ORCID: https://orcid.org/0000-0003-4419-476X, Xu, Xiaohong, Utami, Kagistia H., Sim, Bernice, Huang, Yihui, Harmston, Nathan P., Tay, Yi Lin, Ziaei, Amin, Zeng, Ruizhu, Low, Donovan, Aminkeng, Folefac, Sobata, Radoslaw M., Ginhoux, Florent, Petretto, Enrico and Pouladi, Mahmoud A. 2019. Unbiased profiling of Isogenic Huntington Disease hPSC-Derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects. Cell Reports 26 (9) , pp. 2494-2508. 10.1016/j.celrep.2019.02.008
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Bagnati, Marta, Moreno-Moral, Aida, Ko, Jeong-Hun, Nicod, Jerome, Harmston, Nathan, Imprialou, Martha, Game, Laurence, Gil, Jesus, Petretto, Enrico and Behmoaras, Jacques 2019. Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing. JCI Insight 4 (2) , 2379-3708. 10.1172/jci.insight.125736

Madan, Babita, Harmston, Nathan, Nallan, Gahyathiri, Montoya, Alex, Faull, Peter, Petretto, Enrico and Virshup, David M. 2018. Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis. JCI Journal of Clinical Investigation 128 (12) , pp. 5620-5633. 10.1172/JCI122383

Tjin, Monica Suryana, Chua, Alvin Wen Choong, Moreno-Moral, Aida, Chong, Li Yen, Tang, Po Yin, Harmston, Nathan Peter, Cai, Zuhua, Tan, Bien Keem and Tryggvason, Karl 2018. Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture. Nature Communications 9 , 4432. 10.1038/s41467-018-06934-3

Moreno-Moral, Aida, Bagnati, Marta, Koturan, Surya, Ko, Jeong-Hun, Fonseca, Carmen, Harmston, Nathan, Game, Laurence, Martin, Javier, Ong, Voon, Abraham, David J., Denton, Christopher P, Behmoaras, Jacques and Petretto, Enrico 2018. Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk. Annals of the Rheumatic Diseases 77 , pp. 596-601. 10.1136/annrheumdis-2017-212454

Suresh, Jahnavi, Harmston, Nathan, Lim, Ka Keat, Kaur, Prameet, Jin, Helen Jingshu, Lusk, Jay B., Petretto, Enrico and Tolwinski, Nicholas S. 2017. An embryonic system to assess direct and indirect Wnt transcriptional targets. Scientific Reports 7 , 11092. 10.1038/s41598-017-11519-z

Harmston, Nathan, Ing-Simmons, Elizabeth, Tan, Ge, Perry, Malcolm, Merkenschlager, Matthias and Lenhard, Boris 2017. Topologically associated domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation. Nature Communications 8 , 441. 10.1101/042952
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Alok, Anshula, Lei, Zhengdeng, Jagannathan, N. Suhas, Kaur, Simran, Harmston, Nathan, Rozen, Steven G., Tucker-Kellogg, Lisa and Virshup, David M. 2017. Wnt proteins synergize to activate β-catenin signaling. Development 144 (10) , e1.1-e1.1. 10.1242/dev.154112

Rackham, Owen J L, Langley, Sarah R ORCID: https://orcid.org/0000-0003-4419-476X, Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo and Petretto, Enrico 2017. A Bayesian approach for analysis of whole-genome Bisulfite sequencing data identifies disease-associated changes in DNA Methylation. Genetics 205 (4) , 1443–1458. 10.1534/genetics.116.195008

Rackham, Owen J. L., Langley, Sarah R. ORCID: https://orcid.org/0000-0003-4419-476X, Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo and Petretto, Enrico 2017. A Bayesian approach for analysis of whole-genome bisulphite sequencing data identifies disease-associated changes in DNA methylation. [Online]. BioRXiv. Available at: https://doi.org/10.1101/041715
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Madan, B, Ke, Z, Harmston, N, Ho, S Y, Frois, A O, Alam, J, Jeyaraj, D A, Pendharkar, V, Ghosh, K, Virshup, I H, Manoharan, V, Ong, E H Q, Sangthongpitag, K, Hill, J, Petretto, E, Keller, T H, Lee, M A, Matter, A and Virshup, D M 2016. Wnt addiction of genetically defined cancers reversed by PORCN inhibition. Oncogene 35 , pp. 2197-2207. 10.1038/onc.2015.280

Rackham, J.L. Owen, Langley, Sarah R., Oates, Thomas, Vradi, Eleni, Harmston, Nathan, Srivastava, Prashant K., Behmoaras, Jacques, Dellaportas, Petros, Bottolo, Leonardo and Petretto, Enrico 2016. Approximate Bayesian bisulphite sequencing analysis. [Online]. BioRxiv. Available at: https://doi.org/10.1101/041715

Harmston, Nathan, Ing-Simmons, Elizabeth, Perry, Malcolm, Barešić, Anja and Lenhard, Boris 2015. GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data. BMC Genomics 16 (1) , 963. 10.1186/s12864-015-2140-x

Harmston, Nathan, Barešić, Anja and Lenhard, Boris 2013. The mystery of extreme non-coding conservation. Philosophical Transactions of the Royal Society B: Biological Sciences 368 (1632) , 20130021. 10.1098/rstb.2013.0021

Harmston, Nathan and Lenhard, Boris 2013. Chromatin and epigenetic features of long-range gene regulation. Nucleic Acids Research 41 (15) , pp. 7185-7199. 10.1093/nar/gkt499

Harmston, Nathan, Filsell, Wendy and Stumpf, Michael P.H. 2011. Which species is it? Species-driven gene name disambiguation using random walks over a mixture of adjacency matrices. Bioinformatics 28 (2) , pp. 254-260. 10.1093/bioinformatics/btr640

Harmston, Nathan, Filsell, Wendy and Stumpf, Michael PH 2010. What the papers say: Text mining for genomics and systems biology. Human Genomics 5 (1) , 17. 10.1186/1479-7364-5-1-17

This list was generated on Sat Apr 27 07:35:20 2024 BST.


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