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Saunders, Philippa M., MacLachlan, Bruce J., Widjaja, Jacqueline, Wong, Shu Cheng, Oates, Clare V. L., Rossjohn, Jamie, Vivian, Julian P. and Brooks, Andrew G. 2021. The role of the HLA class I α2 helix in determining ligand hierarchy for the killer cell Ig-like receptor 3DL1. Journal of Immunology 206 (4) , pp. 849-860. 10.4049/jimmunol.2001109 |
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Wirasinha, Rushika C., Davies, Ainsley R., Srivastava, Monika, Sheridan, Julie M., Sng, Xavier Y.X., Delmonte, Ottavia M., Dobbs, Kerry, Loh, Khai L., Miosge, Lisa A., Lee, Cindy Eunhee, Chand, Rochna, Chan, Anna, Yap, Jin Yan, Keller, Michael D., Chen, Karin, Rossjohn, Jamie, La Gruta, Nicole L., Vinuesa, Carola G., Reid, Hugh H., Lionakis, Michail S., Notarangelo, Luigi D., Gray, Daniel H.D., Goodnow, Christopher C., Cook, Matthew C. and Daley, Stephen R.
2021.
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.
Journal of Experimental Medicine
218
(2)
, e20200476.
10.1084/jem.20200476
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Cotton, Rachel N., Cheng, Tan-Yun, Wegrecki, Marcin, Le Nours, Jérôme, Orgill, Dennis P., Pomahac, Bohdan, Talbot, Simon G., Willis, Richard A., Altman, John D., de Jong, Annemieke, Ogg, Graham, Van Rhijn, Ildiko, Rossjohn, Jamie, Clark, Rachael A. and Moody, D. Branch 2021. Human skin is colonized by T cells that recognize CD1a independently of lipid. Journal of Clinical Investigation 131 (1) , e140706. 10.1172/JCI140706 |
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McWilliam, Hamish E. G., Mak, Jeffrey Y. W., Awad, Wael, Zorkau, Matthew, Cruz-Gomez, Sebastian, Lim, Hui Jing, Yan, Yuting, Wormald, Sam, Dagley, Laura F., Eckle, Sidonia B. G., Corbett, Alexandra J., Liu, Haiyin, Li, Shihan, Reddiex, Scott J. J., Mintern, Justine D., Liu, Ligong, McCluskey, James, Rossjohn, Jamie, Fairlie, David P. and Villadangos, Jose A. 2020. Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences 117 (40) , pp. 24974-24985. 10.1073/pnas.2011260117 |
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Assmus, Lisa M., Guan, Jing, Wu, Ting, Farenc, Carine, Sng, Xavier Y. X., Zareie, Pirooz, Nguyen, Angela, Nguyen, Andrea T., Tscharke, David C., Thomas, Paul G., Rossjohn, Jamie, Gras, Stephanie, Croft, Nathan P., Purcell, Anthony W. and La Gruta, Nicole L. 2020. Overlapping peptides elicit distinct CD8+ T cell responses following Influenza A virus infection. Journal of Immunology 205 (7) , pp. 1731-1742. 10.4049/jimmunol.2000689 |
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Habel, Jennifer R., Nguyen, Thi H. O., van de Sandt, Carolien E., Juno, Jennifer A., Chaurasia, Priyanka, Wragg, Kathleen, Koutsakos, Marios, Hensen, Luca, Jia, Xiaoxiao, Chua, Brendon, Zhang, Wuji, Tan, Hyon-Xhi, Flanagan, Katie L., Doolan, Denise L., Torresi, Joseph, Chen, Weisan, Wakim, Linda M., Cheng, Allen C., Doherty, Peter C., Petersen, Jan, Rossjohn, Jamie, Wheatley, Adam K., Kent, Stephen J., Rowntree, Louise C. and Kedzierska, Katherine
2020.
Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype.
Proceedings of the National Academy of Sciences
117
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, pp. 24384-24391.
10.1073/pnas.2015486117
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Suliman, Sara, Gela, Anele, Mendelsohn, Simon C., Iwany, Sarah K., Tamara, Kattya Lopez, Mabwe, Simbarashe, Bilek, Nicole, Darboe, Fatoumatta, Fisher, Michelle, Corbett, Alexandra J., Kjer-Nielsen, Lars, Eckle, Sidonia B. G., Huang, Chuan-Chin, Zhang, Zibiao, Lewinsohn, David M., McCluskey, James, Rossjohn, Jamie, Hatherill, Mark, León, Segundo R., Calderon, Roger I., Lecca, Leonid, Murray, Megan, Scriba, Thomas J., Van Rhijn, Ildiko and Moody, D. Branch 2020. Peripheral blood mucosal-associated invariant T Cells in tuberculosis patients and healthy mycobacterium tuberculosis-exposed controls. Journal of Infectious Diseases 222 (6) , pp. 995-1007. 10.1093/infdis/jiaa173 |
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Rowntree, Louise C., Nguyen, Thi H. O., Farenc, Carine, Halim, Hanim, Hensen, Luca, Rossjohn, Jamie, Kotsimbos, Tom C., Purcell, Anthony W., Kedzierska, Katherine, Gras, Stephanie and Mifsud, Nicole A. 2020. A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07:02–expressing individuals. Journal of Immunology 205 (6) , pp. 1524-1534. 10.4049/jimmunol.2000249 |
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Aguilar, Oscar A., Tanaka, Miho, Balaji, Gautham R., Berry, Richard, Rossjohn, Jamie, Lanier, Lewis L. and Carlyle, James R. 2020. Tetramer immunization and selection followed by CELLISA screening to generate monoclonal antibodies against the mouse cytomegalovirus m12 immunoevasin. Journal of Immunology 205 (6) , pp. 1709-1717. 10.4049/jimmunol.2000687 |
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Reijneveld, Josephine F., Ocampo, Tonatiuh A., Shahine, Adam, Gully, Benjamin S., Vantourout, Pierre, Hayday, Adrian C., Rossjohn, Jamie, Moody, D. Branch and Van Rhijn, Ildiko
2020.
Human γδ T cells recognize CD1b by two distinct mechanisms.
Proceedings of the National Academy of Sciences
117
(37)
, pp. 22933-22952.
10.1073/pnas.2010545117
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Schultz-Cherry, Stacey, Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O. and Kedzierska, Katherine
2020.
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.
PLoS Pathogens
16
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, e1008714.
10.1371/journal.ppat.1008714
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Junghans, Victoria, Chouliara, Manto, Santos, Ana Mafalda, Hatherley, Deborah, Petersen, Jan, Dam, Tommy, Svensson, Lena M., Rossjohn, Jamie, Davis, Simon J. and Jönsson, Peter
2020.
Effects of a local auxiliary protein on the two-dimensional affinity of a TCR–peptide MHC interaction.
Journal of Cell Science
133
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, jcs245985.
10.1242/jcs.245985
Item availability restricted. |
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Toubal, Amine, Kiaf, Badr, Beaudoin, Lucie, Cagninacci, Lucie, Rhimi, Moez, Fruchet, Blandine, da Silva, Jennifer, Corbett, Alexandra J., Simoni, Yannick, Lantz, Olivier, Rossjohn, Jamie, McCluskey, James, Lesnik, Philippe, Maguin, Emmanuelle and Lehuen, Agnès
2020.
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity.
Nature Communications
11
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, 3755.
10.1038/s41467-020-17307-0
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Howson, Lauren J., Awad, Wael, von Borstel, Anouk, Lim, Hui Jing, McWilliam, Hamish E. G., Sandoval-Romero, Maria L., Majumdar, Shamik, Hamzeh, Abdul Rezzak, Andrews, Thomas D., McDermott, David H., Murphy, Philip M., Le Nours, Jérôme, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., McCluskey, James, Villadangos, Jose A., Cook, Matthew C., Turner, Stephen J., Davey, Martin S., Ojaimi, Samar and Rossjohn, Jamie 2020. Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science Immunology 5 (49) , eabc9492. 10.1126/sciimmunol.abc9492 |
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Littler, Dene R., Gully, Benjamin S., Colson, Rhys N. and Rossjohn, Jamie
2020.
Crystal structure of the SARS-CoV-2 non-structural protein 9, Nsp9.
iScience
23
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, 101258.
10.1016/j.isci.2020.101258
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Saunders, Philippa M., MacLachlan, Bruce J., Pymm, Phillip, Illing, Patricia T., Deng, Yuanchen, Wong, Shu Cheng, Oates, Clare V. L., Purcell, Anthony W., Rossjohn, Jamie, Vivian, Julian P. and Brooks, Andrew G. 2020. The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proceedings of the National Academy of Sciences 117 (21) , pp. 11636-11647. 10.1073/pnas.1920570117 |
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Awad, Wael, Ler, Geraldine J. M., Xu, Weijun, Keller, Andrew N., Mak, Jeffrey Y. W., Lim, Xin Yi, Liu, Ligong, Eckle, Sidonia B. G., Le Nours, Jérôme, McCluskey, James, Corbett, Alexandra J., Fairlie, David P. and Rossjohn, Jamie 2020. The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature Immunology 21 (4) , pp. 400-411. 10.1038/s41590-020-0616-6 |
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Salio, Mariolina, Awad, Wael, Veerapen, Natacha, Gonzalez-Lopez, Claudia, Kulicke, Corinna, Waithe, Dominic, Martens, Anne W. J., Lewinsohn, David M., Hobrath, Judith V., Cox, Liam R., Rossjohn, Jamie, Besra, Gurdyal S. and Cerundolo, Vincenzo
2020.
Ligand-dependent downregulation of MR1 cell surface expression.
Proceedings of the National Academy of Sciences
117
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, pp. 10465-10475.
10.1073/pnas.2003136117
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Fugger, Lars, Jensen, Lise Torp and Rossjohn, Jamie 2020. Challenges, progress, and prospects of developing therapies to treat autoimmune diseases. Cell 181 (1) , pp. 63-80. 10.1016/j.cell.2020.03.007 |
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McSharry, Brian P., Samer, Carolyn, McWilliam, Hamish E.G., Ashley, Caroline L., Yee, Michael B., Steain, Megan, Liu, Ligong, Fairlie, David P., Kinchington, Paul R., McCluskey, James, Abendroth, Allison, Villadangos, Jose A., Rossjohn, Jamie and Slobedman, Barry
2020.
Virus-mediated suppression of the antigen presentation Molecule MR1.
Cell Reports
30
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, 2948-2962e4.
10.1016/j.celrep.2020.02.017
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Loh, Liyen, Gherardin, Nicholas A., Sant, Sneha, Grzelak, Ludivine, Crawford, Jeremy Chase, Bird, Nicola L., Koay, Hui-Fern, van de Sandt, Carolien E., Moreira, Marcela L., Lappas, Martha, Allen, E. Kaitlynn, Crowe, Jane, Loudovaris, Thomas, Flanagan, Katie L., Quinn, Kylie M., Rossjohn, Jamie, Thomas, Paul G., Eckle, Sidonia B. G., McCluskey, James, Godfrey, Dale I. and Kedzierska, Katherine 2020. Human mucosal-associated invariant T cells in older individuals display expanded TCRαβ clonotypes with potent antimicrobial responses. Journal of Immunology 204 (5) , pp. 1119-1133. 10.4049/jimmunol.1900774 |
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Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara, Ager, Ann, Parker, Alan L., Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie, Svane, Inge Marie, Phillips, John D. and Sewell, Andrew K. 2020. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21 , 178 - 185. 10.1038/s41590-019-0578-8 |
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Berry, Richard, Watson, Gabrielle M., Jonjic, Stipan, Degli-Esposti, Mariapia A. and Rossjohn, Jamie 2020. Modulation of innate and adaptive immunity by cytomegaloviruses. Nature Reviews Immunology 20 , pp. 113-127. 10.1038/s41577-019-0225-5 |
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Rowntree, Louise C., van den Heuvel, Heleen, Sun, Jessica, D'Orsogna, Lloyd J., Nguyen, Thi H. O., Claas, Frans H. J., Rossjohn, Jamie, Kotsimbos, Tom C., Purcell, Anthony W. and Mifsud, Nicole A.
2020.
Preferential HLA-B27 allorecognition displayed by multiple cross-reactive antiviral CD8+ T cell receptors.
Frontiers in Immunology
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, 248.
10.3389/fimmu.2020.00248
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Ting, Yi Tian, Dahal-Koirala, Shiva, Kim, Hui Shi Keshia, Qiao, Shuo-Wang, Neumann, Ralf S., Lundin, Knut E. A., Petersen, Jan, Reid, Hugh H., Sollid, Ludvig M. and Rossjohn, Jamie
2020.
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease.
Proceedings of the National Academy of Sciences
117
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, pp. 3063-3073.
10.1073/pnas.1914308117
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Petersen, Jan, Ciacchi, Laura, Tran, Mai T., Loh, Khai Lee, Kooy-Winkelaar, Yvonne, Croft, Nathan P., Hardy, Melinda Y., Chen, Zhenjun, McCluskey, James, Anderson, Robert P., Purcell, Anthony W., Tye-Din, Jason A., Koning, Frits, Reid, Hugh H. and Rossjohn, Jamie 2020. T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nature Structural and Molecular Biology 27 (1) , pp. 49-61. 10.1038/s41594-019-0353-4 |
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Nicolai, Sarah, Wegrecki, Marcin, Cheng, Tan-Yun, Bourgeois, Elvire A., Cotton, Rachel N., Mayfield, Jacob A., Monnot, Gwennaëlle C., Le Nours, Jérôme, Van Rhijn, Ildiko, Rossjohn, Jamie, Moody, D. Branch and de Jong, Annemieke 2020. Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Science Immunology 5 (43) , eaax5430. 10.1126/sciimmunol.aax5430 |
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Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Koay, Hui-Fern, Meehan, Bronwyn, Zhao, Zhe, Pediongco, Troi, Shi, Mai, Zhu, Tianyuan, Wang, Bingjie, Kjer-Nielsen, Lars, Eckle, Sidonia B. G., Rossjohn, Jamie, Fairlie, David P., Godfrey, Dale I., Strugnell, Richard A., McCluskey, James and Corbett, Alexandra J. 2019. Characterization and purification of mouse mucosal-associated invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e89. 10.1002/cpim.89 |
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Souter, Michael N.T., Loh, Liyen, Li, Shihan, Meehan, Bronwyn S., Gherardin, Nicholas A., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., Kedzierska, Katherine, Pellicci, Daniel G., Chen, Zhenjun, Kjer-Nielsen, Lars, Corbett, Alexandra J., McCluskey, James and Eckle, Sidonia B. G. 2019. Characterization of Human Mucosal-associated Invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e90. 10.1002/cpim.90 |
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Picarda, Elodie, Bézie, Séverine, Usero, Lorena, Ossart, Jason, Besnard, Marine, Halim, Hanim, Echasserieau, Klara, Usal, Claire, Rossjohn, Jamie, Bernardeau, Karine, Gras, Stéphanie and Guillonneau, Carole
2019.
Cross-reactive donor-specific CD8+ Tregs efficiently prevent transplant rejection.
Cell Reports
29
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, 4245-4255.e6.
10.1016/j.celrep.2019.11.106
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Le Nours, Jérôme, Gherardin, Nicholas A., Ramarathinam, Sri H., Awad, Wael, Wiede, Florian, Gully, Benjamin S., Khandokar, Yogesh, Praveena, T., Wubben, Jacinta M., Sandow, Jarrod J., Webb, Andrew I., von Borstel, Anouk, Rice, Michael T., Redmond, Samuel J., Seneviratna, Rebecca, Sandoval-Romero, Maria L., Li, Shihan, Souter, Michael N. T., Eckle, Sidonia B. G., Corbett, Alexandra J., Reid, Hugh H., Liu, Ligong, Fairlie, David P., Giles, Edward M., Westall, Glen P., Tothill, Richard W., Davey, Martin S., Berry, Richard, Tiganis, Tony, McCluskey, James, Pellicci, Daniel G., Purcell, Anthony W., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie 2019. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science 366 (6472) , pp. 1522-1527. 10.1126/science.aav3900 |
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Reinink, Peter, Shahine, Adam, Gras, Stephanie, Cheng, Tan-Yun, Farquhar, Rachel, Lopez, Kattya, Suliman, Sara A., Reijneveld, Josephine F., Le Nours, Jérôme, Tan, Li Lynn, León, Segundo R., Jimenez, Judith, Calderon, Roger, Lecca, Leonid, Murray, Megan B., Rossjohn, Jamie, Moody, D. Branch and Van Rhijn, Ildiko 2019. A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins. Journal of Immunology 203 (12) , pp. 3395-3046. 10.4049/jimmunol.1900872 |
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van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J., Nguyen, T. H. O., Gras, S., Chen, W. and Kedzierska, K.
2019.
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph.
Nature Communications
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10.1038/s41467-019-13346-4
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Almeida, Catarina F., Sundararaj, Srinivasan, Le Nours, Jérôme, Praveena, T., Cao, Benjamin, Burugupalli, Satvika, Smith, Dylan G. M., Patel, Onisha, Brigl, Manfred, Pellicci, Daniel G., Williams, Spencer J., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie
2019.
Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors.
Nature Communications
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10.1038/s41467-019-12941-9
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Lim Kam Sian, Terry C. C., Indumathy, Saranjah, Halim, Hanim, Greule, Anja, Cryle, Max J., Bowness, Paul, Rossjohn, Jamie, Gras, Stephanie, Purcell, Anthony W. and Schittenhelm, Ralf B. 2019. Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. Journal of Biological Chemistry 294 (52) , pp. 20185-20195. 10.1074/jbc.RA119.010257 |
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Wang, Huimeng, Kjer-Nielsen, Lars, Shi, Mai, D?Souza, Criselle, Pediongco, Troi J., Cao, Hanwei, Kostenko, Lyudmila, Lim, Xin Yi, Eckle, Sidonia B. G., Meehan, Bronwyn S., Zhu, Tianyuan, Wang, Bingjie, Zhao, Zhe, Mak, Jeffrey Y. W., Fairlie, David P., Teng, Michele W. L., Rossjohn, Jamie, Yu, Di, de St Groth, Barbara Fazekas, Lovrecz, George, Lu, Louis, McCluskey, James, Strugnell, Richard A., Corbett, Alexandra J. and Chen, Zhenjun 2019. IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology 4 (41) , eaaw0402. 10.1126/sciimmunol.aaw0402 |
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Deuss, Felix A., Watson, Gabrielle M., Goodall, Katharine J., Leece, Isobel, Chatterjee, Sayantani, Fu, Zhihui, Thaysen-Andersen, Morten, Andrews, Daniel M., Rossjohn, Jamie and Berry, Richard 2019. Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1. Journal of Biological Chemistry 294 (33) , pp. 12534-12546. 10.1074/jbc.RA119.009261 |
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Niehrs, Annika, Garcia-Beltran, Wilfredo F., Norman, Paul J., Watson, Gabrielle M., Hölzemer, Angelique, Chapel, Anaïs, Richert, Laura, Pommerening-Röser, Andreas, Körner, Christian, Ozawa, Mikki, Martrus, Glòria, Rossjohn, Jamie, Lee, Jar-How, Berry, Richard, Carrington, Mary and Altfeld, Marcus 2019. A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44. Nature Immunology 20 (9) , pp. 1129-1137. 10.1038/s41590-019-0448-4 |
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Schinkelshoek, M.S., Fronczek, R., Kooy-Winkelaar, E.M.C., Petersen, J., Reid, H.H., van der Heide, A., Drijfhout, J.W., Rossjohn, Jamie, Lammers, G.J. and Koning, F.
2019.
H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls.
Journal of Neuroimmunology
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10.1016/j.jneuroim.2019.04.009
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Koutsakos, Marios, McWilliam, Hamish E. G., Aktepe, Turgut E., Fritzlar, Svenja, Illing, Patricia T., Mifsud, Nicole A., Purcell, Anthony W., Rockman, Steve, Reading, Patrick C., Vivian, Julian P., Rossjohn, Jamie, Brooks, Andrew G., Mackenzie, Jason M., Mintern, Justine D., Villadangos, Jose A., Nguyen, Thi H. O. and Kedzierska, Katherine
2019.
Downregulation of MHC class I expression by influenza A and B viruses.
Frontiers in Immunology
10
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Koutsakos, Marios, Illing, Patricia T., Nguyen, Thi H. O., Mifsud, Nicole A., Crawford, Jeremy Chase, Rizzetto, Simone, Eltahla, Auda A., Clemens, E. Bridie, Sant, Sneha, Chua, Brendon Y., Wong, Chinn Yi, Allen, E. Kaitlynn, Teng, Don, Dash, Pradyot, Boyd, David F., Grzelak, Ludivine, Zeng, Weiguang, Hurt, Aeron C., Barr, Ian, Rockman, Steve, Jackson, David C., Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Wakim, Linda M., Rossjohn, Jamie, Vijaykrishna, Dhanasekaran, Luciani, Fabio, Thomas, Paul G., Gras, Stephanie, Purcell, Anthony W. and Kedzierska, Katherine 2019. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nature Immunology 20 , pp. 613-625. 10.1038/s41590-019-0320-6 |
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Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt 2019. A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical 284 , pp. 281-288. 10.1016/j.snb.2018.12.099 |
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Mayassi, Toufic, Ladell, Kristin, Gudjonson, Herman, McLaren, James E., Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie, Price, David A. and Jabri, Bana
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Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease.
Cell
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Neier, Steven C., Ferrer, Alejandro, Wilton, Katelynn M., Smith, Stephen E. P., Kelcher, April M. H., Pavelko, Kevin D., Canfield, Jenna M., Davis, Tessa R., Stiles, Robert J., Chen, Zhenjun, McCluskey, James, Burrows, Scott R., Rossjohn, Jamie, Hebrink, Deanne M., Carmona, Eva M., Limper, Andrew H., Kappes, Dietmar J., Wettstein, Peter J., Johnson, Aaron J., Pease, Larry R., Daniels, Mark A., Neuhauser, Claudia, Gil, Diana and Schrum, Adam G. 2019. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology 4 (32) , eaal2201. 10.1126/sciimmunol.aal2201 |
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Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E. A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie and Sollid, Ludvig M. 2019. Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes. Journal of Biological Chemistry 294 (3) , pp. 941-952. 10.1074/jbc.RA118.005736 |
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Shahine, Adam, Reinink, Peter, Reijneveld, Josephine F., Gras, Stephanie, Holzheimer, Mira, Cheng, Tan-Yun, Minnaard, Adriaan J., Altman, John D., Lenz, Steffi, Prandi, Jacques, Kubler-Kielb, Joanna, Moody, D. Branch, Rossjohn, Jamie and Van Rhijn, Ildiko
2019.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nature Communications
10
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10.1038/s41467-018-07898-0
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Ooi, Joshua D., Jiang, Jhih-Hang, Eggenhuizen, Peter J., Chua, Ling L., van Timmeren, Mirjan, Loh, Khai L., O?Sullivan, Kim M., Gan, Poh Y., Zhong, Yong, Tsyganov, Kirill, Shochet, Lani R., Ryan, Jessica, Stegeman, Coen A., Fugger, Lars, Reid, Hugh H., Rossjohn, Jamie, Heeringa, Peter, Holdsworth, Stephen R., Peleg, Anton Y. and Kitching, A. Richard
2019.
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.
Nature Communications
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10.1038/s41467-019-11255-0
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Grant, Emma J., Josephs, Tracy M., Loh, Liyen, Clemens, E. Bridie, Sant, Sneha, Bharadwaj, Mandvi, Chen, Weisan, Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine
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Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans.
Nature Communications
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Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P. and Purcell, Anthony W. 2018. HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature Communications 9 (1) , 4693. 10.1038/s41467-018-07109-w |
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Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeastGlaciozyma antarctica PI12.
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Petersen, Jan, Kooy-Winkelaar, Yvonne, Loh, Khai Lee, Tran, Mai, van Bergen, Jeroen, Koning, Frits, Rossjohn, Jamie and Reid, Hugh H. 2016. Diverse T cell receptor gene usage in HLA-DQ8-associated celiac disease converges into a consensus binding solution. Structure 24 (10) , pp. 1643-1657. 10.1016/j.str.2016.07.010 |
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Kim, Ji Hyung, Hu, Yu, Yongqing, Tang, Kim, Jessica, Hughes, Victoria A., Le Nours, Jerome, Marquez, Elsa A., Purcell, Anthony W., Wan, Qi, Sugita, Masahiko, Rossjohn, Jamie and Winau, Florian 2016. CD1a on Langerhans cells controls inflammatory skin disease. Nature Immunology 17 (10) , pp. 1159-1166. 10.1038/ni.3523 |
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Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Bridgeman, John S, Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D, Tungatt, Katie, Dolton, Garry, Sewell, Andrew, Price, David A, Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina
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Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination.
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Loh, Liyen, Wang, Zhongfang, Sant, Sneha, Koutsakos, Marios, Jegaskanda, Sinthujan, Corbett, Alexandra J., Liu, Ligong, Fairlie, David P., Crowe, Jane, Rossjohn, Jamie, Xu, Jianqing, Doherty, Peter C., McCluskey, James and Kedzierska, Katherine
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Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation.
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Sullivan, Lucy C., Berry, Richard, Sosnin, Natasha, Widjaja, Jacqueline M. L., Deuss, Felix A., Balaji, Gautham R., LaGruta, Nicole L., Mirams, Michiko, Trapani, Joseph A., Rossjohn, Jamie, Brooks, Andrew G. and Andrews, Daniel M.
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Recognition of the Major Histocompatibility Complex (MHC) class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C.
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Jönsson, Peter, Southcombe, Jennifer H., Santos, Ana Mafalda, Huo, Jiandong, Fernandes, Ricardo A., McColl, James, Lever, Melissa, Evans, Edward J., Hudson, Alexander, Chang, Veronica T., Hanke, Tomá?, Godkin, Andrew, Dunne, Paul D., Horrocks, Mathew H., Palayret, Matthieu, Screaton, Gavin R., Petersen, Jan, Rossjohn, Jamie, Fugger, Lars, Dushek, Omer, Xu, Xiao-Ning, Davis, Simon J. and Klenerman, David
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Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
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Vinton, Carol, Wu, Fan, Rossjohn, Jamie, Matsuda, Kenta, McCluskey, James, Hirsch, Vanessa, Price, David, Brenchley, Jason M. and Silvestri, G. 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9) , pp. 4520-4529. 10.1128/JVI.02876-15 |
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Benati, Daniela, Galperin, Moran, Lambotte, Olivier, Gras, Stéphanie, Lim, Annick, Mukhopadhyay, Madhura, Nouël, Alexandre, Campbell, Kristy-Anne, Lemercier, Brigitte, Claireaux, Mathieu, Hendou, Samia, Lechat, Pierre, de Truchis, Pierre, Boufassa, Faroudy, Rossjohn, Jamie, Delfraissy, Jean-François, Arenzana-Seisdedos, Fernando and Chakrabarti, Lisa A. 2016. Public T cell receptors confer high-avidity CD4 responses to HIV controllers. The Journal of Clinical Investigation 126 (6) , pp. 2093-2108. 10.1172/JCI83792 |
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Valkenburg, Sophie A., Josephs, Tracy M., Clemens, E. Bridie, Grant, Emma J., Nguyen, Thi H. O., Wang, George C., Price, David, Miller, Adrian, Tong, Steven Y. C., Thomas, Paul G., Doherty, Peter C., Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine 2016. Molecular basis for universal HLA-A*0201 - restricted CD8+ T-cell immunity against influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113 (16) , pp. 4440-4445. 10.1073/pnas.1603106113 |
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Du, V. Y., Bansal, A., Carlson, J., Salazar-Gonzalez, J. F., Salazar, M. G., Ladell, Kristin Ingrid, Gras, S., Josephs, T. M., Heath, S. L., Price, David, Rossjohn, Jamie, Hunter, E. and Goepfert, P. A. 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196 (8) , pp. 3276-3286. 10.4049/jimmunol.1502411 |
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Saunders, Philippa M., Pymm, Phillip, Pietra, Gabriella, Hughes, Victoria A., Hitchen, Corinne, O?Connor, Geraldine M., Loiacono, Fabrizio, Widjaja, Jacqueline, Price, David, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G. and Vivian, Julian P.
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Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.
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McWilliam, Hamish E G, Eckle, Sidonia B G, Theodossis, Alex, Liu, Ligong, Chen, Zhenjun, Wubben, Jacinta M, Fairlie, David P, Strugnell, Richard A, Mintern, Justine D, McCluskey, James, Rossjohn, Jamie and Villadangos, Jose A 2016. The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1. Nature Immunology 10.1038/ni.3416 |
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Rossjohn, Jamie and Koning, F. 2016. A biased view toward celiac disease. Mucosal Immunology 9 (3) , pp. 583-586. 10.1038/mi.2016.17 |
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Le Nours, Jérôme, Praveena, T., Pellicci, Daniel G., Gherardin, Nicholas A., Ross, Fiona J., Lim, Ricky T., Besra, Gurdyal S., Keshipeddy, Santosh, Richardson, Stewart K., Howell, Amy R., Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie and Uldrich, Adam P. 2016. Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nature Communications 7 , 10570. 10.1038/ncomms10570 |
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Gherardin, Nicholas A., Keller, Andrew N., Woolley, Rachel E., Le Nours, Jérôme, Ritchie, David S., Neeson, Paul J., Birkinshaw, Richard W., Eckle, Sidonia B.G., Waddington, John N., Liu, Ligong, Fairlie, David P., Uldrich, Adam P., Pellicci, Daniel G., McCluskey, James, Godfrey, Dale I. and Rossjohn, Jamie 2016. Diversity of T cells restricted by the MHC class I-related molecule MR1 facilitates differential antigen recognition. Immunity 44 (1) , pp. 32-45. 10.1016/j.immuni.2015.12.005 |
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Koay, Hui Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Siodonia B. G., Meehan, Bronwyn, d’Udekem, Yves, Konstantinov, Igor, Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Kedzirska, Katherine, Berzins, Stuart P., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Peellicci, Daniel G. 2016. Thymic precursors to the Mucosal-Associated Invariant T cell lineage. European Journal of Immunology 46 (1) , p. 256. 10.1002/eji.201670015 |
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Beringer, Dennis X., Kleijwegt, Fleur S., Wiede, Florian, van der Slik, Arno R., Loh, Khai Lee, Petersen, Jan, Dudek, Nadine L., Duinkerken, Gaby, Laban, Sandra, Joosten, Antoinette, Vivian, Julian P., Chen, Zhenjun, Uldrich, Adam P., Godfrey, Dale I., McCluskey, James, Price, David A., Radford, Kristen J., Purcell, Anthony W., Nikolic, Tatjana, Reid, Hugh H., Tiganis, Tony, Roep, Bart O. and Rossjohn, Jamie 2015. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology 16 , pp. 1153-1161. 10.1038/ni.3271 |
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Clemens, E Bridie, Grant, Emma J, Wang, Zhongfang, Gras, Stephanie, Tipping, Peta, Rossjohn, Jamie, Miller, Adrian, Tong, Steven YC and Kedzierska, Katherine
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Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians.
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Gartlan, K. H., Markey, K. A., Varelias, A., Bunting, M. D., Koyama, M., Kuns, R. D., Raffelt, N. C., Olver, S. D., Lineburg, K. E., Cheong, M., Teal, B. E., Lor, M., Comerford, I., Teng, M. W. L., Smyth, M. J., McCluskey, J., Rossjohn, Jamie, Stockinger, B., Boyle, G. M., Lane, S. W., Clouston, A. D., McColl, S. R., MacDonald, K. P. A. and Hill, G. R. 2015. Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood 126 (13) , pp. 1609-1620. 10.1182/blood-2015-01-622662 |
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Saunders, Philippa M., Vivian, Julian P., O'Connor, Geraldine M., Sullivan, Lucy C., Pymm, Phillip, Rossjohn, Jamie and Brooks, Andrew G. 2015. A bird's eye view of NK cell receptor interactions with their MHC class I ligands. Immunological Reviews 267 (1) , pp. 148-166. 10.1111/imr.12319 |
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Petersen, J., van Bergen, J., Loh, K. L., Kooy-Winkelaar, Y., Beringer, D. X., Thompson, A., Bakker, S. F., Mulder, C. J. J., Ladell, Kristin, McLaren, James Edward, Price, David, Rossjohn, Jamie, Reid, H. H. and Koning, F. 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194 (12) , pp. 6112-6122. 10.4049/jimmunol.1500161 |
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McWilliam, Hamish EG, Birkinshaw, Richard W, Villadangos, Jose A, McCluskey, James and Rossjohn, Jamie 2015. MR1 presentation of vitamin B-based metabolite ligands. Current Opinion in Immunology 34 , pp. 28-34. 10.1016/j.coi.2014.12.004 |
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Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, John James, Purcell, A. W., Rossjohn, Jamie, Gras, S. and Burrows, S. R. 2015. T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells. The Journal of Immunology 194 (10) , pp. 4668-4675. 10.4049/jimmunol.1500233 |
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O'Connor, Geraldine M., Vivian, Julian P., Gostick, Emma, Pymm, Phillip, Lafont, Bernard A. P., Price, David, Rossjohn, Jamie, Brooks, Andrew G., McVicar, Daniel W. and Kirchhoff, F. 2015. Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1. Journal of Virology 89 (10) , pp. 5213-5221. 10.1128/JVI.03586-14 |
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Magalhaes, Isabelle, Pingris, Karine, Poitou, Christine, Bessoles, Stéphanie, Venteclef, Nicolas, Kiaf, Badr, Beaudoin, Lucie, Da Silva, Jennifer, Allatif, Omran, Rossjohn, Jamie, Kjer-Nielsen, Lars, McCluskey, James, Ledoux, Séverine, Genser, Laurent, Torcivia, Adriana, Soudais, Claire, Lantz, Olivier, Boitard, Christian, Aron-Wisnewsky, Judith, Larger, Etienne, Clément, Karine and Lehuen, Agnès 2015. Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. The Journal of Clinical Investigation 125 (4) , pp. 1752-1762. 10.1172/JCI78941 |
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Birkinshaw, Richard W., Pellicci, Daniel G., Cheng, Tan-Yun, Keller, Andrew N., Sandoval-Romero, Maria, Gras, Stephanie, de Jong, Annemieke, Uldrich, Adam P., Moody, D. Branch, Godfrey, Dale I. and Rossjohn, Jamie 2015. αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nature Immunology 16 , pp. 258-266. 10.1038/ni.3098 |
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Moradi, Shoeib, Berry, Richard, Pymm, Phillip, Hitchen, Corinne, Beckham, Simone A., Wilce, Matthew C.J., Walpole, Nicholas G., Clements, Craig S., Reid, Hugh H., Perugini, Matthew A., Brooks, Andrew G., Rossjohn, Jamie and Vivian, Julian P. 2015. The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4. The Journal of Biological Chemistry 10.1074/jbc.M114.612291 |
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Rossjohn, Jamie, Gras, Stephanie, Miles, John James, Turner, Stephen J., Godfrey, Dale I. and McCluskey, James 2015. T cell antigen receptor recognition of antigen-presenting molecules. Annual Review of Immunology 33 (1) , pp. 169-200. 10.1146/annurev-immunol-032414-112334 |
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Miles, John James, McCluskey, James, Rossjohn, Jamie and Gras, Stephanie 2015. Understanding the complexity and malleability of T-cell recognition. Immunology and Cell Biology 93 (5) , pp. 433-441. 10.1038/icb.2014.112 |
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Saunders, P. M., Vivian, J. P., Baschuk, N., Beddoe, T., Widjaja, J., O'Connor, G. M., Hitchen, C., Pymm, P., Andrews, D. M., Gras, S., McVicar, D. W., Rossjohn, Jamie and Brooks, A. G. 2015. The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope. The Journal of Immunology 194 (2) , pp. 781-789. 10.4049/jimmunol.1402542 |
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Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G.D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M., Gras, Stephanie and van Veelen, Peter A. 2014. Naturally processed non-canonical HLA-A*02:01 presented peptides. The Journal of Biological Chemistry 290 (5) , pp. 2593-2603. 10.1074/jbc.M114.607028 |
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Nivarthi, Usha K., Gras, Stephanie, Kjer-Nielsen, Lars, Berry, Richard, Lucet, Isabelle S., Miles, John J., Tracy, Samantha L., Purcell, Anthony W., Bowden, David S., Hellard, Margaret, Rossjohn, Jamie, McCluskey, James and Bharadwaj, Mandvi 2014. An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant. The Journal of Immunology 193 (11) , pp. 5402-5413. 10.4049/jimmunol.1401357 |
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Birnbaum, Michael E., Berry, Richard, Hsiao, Yu-Shan, Chen, Zhenjun, Shingu-Vazquez, Miguel A., Yu, Xiaoling, Waghray, Deepa, Fischer, Suzanne, McCluskey, James, Rossjohn, Jamie, Walz, Thomas and Garcia, K. Christopher 2014. Molecular architecture of the αβ T cell receptor–CD3 complex. Proceedings of the National Academy of Sciences of the United States of America 111 (49) , pp. 17576-17581. 10.1073/pnas.1420936111 |
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Fernandez, Caroline S., Amarasena, Thakshila, Kelleher, Anthony D., Rossjohn, Jamie, McClusky, James, Godfrey, Dale I. and Kent, Stephen J. 2014. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunology and Cell Biology 93 (2) , pp. 177-188. 10.1038/icb.2014.91 |
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Trujillo, Jonathan A., Croft, Nathan P., Dudek, Nadine L., Channappanavar, Rudragouda, Theodossis, Alex, Webb, Andrew I., Dunstone, Michelle A., Illing, Patricia T., Butler, Noah S., Fett, Craig, Tscharke, David C., Rossjohn, Jamie, Perlman, Stanley and Purcell, Anthony W. 2014. The cellular redox environment alters antigen presentation. The Journal of Biological Chemistry 289 (40) , pp. 27979-91. 10.1074/jbc.M114.573402 |
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Berry, Richard, Vivian, Julian P., Deuss, Felix A., Balaji, Gautham R., Saunders, Philipa M., Lin, Jie, Littler, Dene R., Brooks, Andrew G. and Rossjohn, Jamie 2014. The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins. The Journal of Biological Chemistry 289 (34) , pp. 23753-23763. 10.1074/jbc.M114.584128 |
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Trujillo, Jonathan A., Gras, Stephanie, Twist, Kelly-Anne, Croft, Nathan P., Channappanavar, Rudragouda, Rossjohn, Jamie, Purcell, Anthony W. and Perlman, Stanley 2014. Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes. The Journal of Immunology 192 (11) , pp. 5245-5256. 10.4049/jimmunol.1400111 |
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Van Rhijn, Ildiko, Gherardin, Nicholas A., Kasmar, Anne, de Jager, Wilco, Pellicci, Daniel G., Kostenko, Lyudmila, Tan, Li Lynn, Bhati, Mugdha, Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie and Moody, D. Branch 2014. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T cell repertoire. Journal of Immunology 192 (9) , pp. 4054-4060. 10.4049/jimmunol.1400158 |
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Petersen, Jan, Montserrat, Veronica, Mujico, Jorge R., Loh, Khai Lee, Beringer, Dennis X., van Lummel, Menno, Thompson, Allan, Mearin, M Luisa, Schweizer, Joachim, Kooy-Winkelaar, Yvonne, van Bergen, Jeroen, Drijfhout, Jan W., Kan, Wan-Ting, La Gruta, Nicole L, Anderson, Robert P., Reid, Hugh H., Koning, Frits and Rossjohn, Jamie 2014. T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease. Nature Structural and Molecular Biology 21 (5) , pp. 480-488. 10.1038/nsmb.2817 |
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Liu, Yu Chih, Chen, Zhenjun, Neller, Michelle A., Miles, John J,, Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie and Gras, Stephanie 2014. A molecular basis for the interplay between T cells, viral mutants and human leukocyte antigen micropolymorphism. The Journal of Biological Chemistry 289 (24) , pp. 16688-98. 10.1074/jbc.M114.563502 |
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Corbett, Alexandra J., Eckle, Sidonia B.G., Birkinshaw, Richard W., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y.W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie and McCluskey, James 2014. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509 (7500) , pp. 361-365. 10.1038/nature13160 |
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O'Connor, G.eraldine M., Vivian, Julian P., Widjaja, Jacqueline M., Bridgeman, John S., Gostick, Emma, Lafont, Bernard A. P., Anderson, Stephen K., Price, David A., Brooks, Andrew G., Rossjohn, Jamie and McVicar, Daniel W.
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Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity.
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Bhati, Mugdha, Cole, David, McCluskey, James, Sewell, Andrew K. and Rossjohn, Jamie 2014. The versatility of the αβ T-cell antigen receptor. Protein Science 23 (3) , pp. 260-272. 10.1002/pro.2412 |
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Berry, Richard, Rossjohn, Jamie and Brooks, Andrew G. 2014. The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination. Immunology and Cell Biology 92 , pp. 214-220. 10.1038/icb.2013.100 |
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Smith, Corey, Gras, Stephanie, Brennan, Rebekah M., Bird, Nicola L., Valkenburg, Sophie A., Twist, Kelly-Anne, Burrows, Jacqueline M., Miles, John James, Chambers, Daniel, Bell, Scott, Campbell, Scott, Kedzierska, Katherine, Burrows, Scott R, Rossjohn, Jamie and Khanna, Rajiv 2014. Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Scientific Reports 4 , 3993. 10.1038/srep03993 |
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Stifter, Sebastian A., Gould, Jodee A., Mangan, Niamh E., Reid, Hugh H., Rossjohn, Jamie, Hertzog, Paul J. and de Weerd, Nicole A. 2014. Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells. Protein Expression and Purification 94 , pp. 7-14. 10.1016/j.pep.2013.10.019 |
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Berry, Richard, Headey, Stephen J., Call, Melissa J., McCluskey, James, Tregaskes, Clive A., Kaufman, Jim, Koh, Ruide, Scanlon, Martin J., Call, Matthew E. and Rossjohn, Jamie 2014. Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αβT cell receptor. The Journal of Biological Chemistry 289 (12) , pp. 8240-8251. 10.1074/jbc.M113.544965 |
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Quiñones-Parraa, Sergio, Grant, Emma, Loha, Liyen, Nguyena, Thi H. O., Campbell, Kirsty-Anne, Tong, Steven Y. C., Miller, Adrian, Doherty, Peter C., Vijaykrishnag, Dhanasekaran, Rossjohn, Jamie, Gras, Stephanie and Kedzierskaa, Katherine 2014. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proceedings of the National Academy of Sciences of the United States of America 111 (3) , pp. 1049-1054. 10.1073/pnas.1322229111 |
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Ng, Natasha M., Littler, Dene R., Paton, Adrienne W., Le Nours, Jérôme, Rossjohn, Jamie, Paton, James C. and Beddoe, Travis 2013. EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Structure 21 (11) , pp. 2003-2013. 10.1016/j.str.2013.08.024 |
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Scally, S., Petersen, J., Law, S., Dudek, N., Nel, H., Loh, K., Wijeyewickrema, L., Eckle, S., van Heemst, J., Pike, R., McCluskey, J., Toes, R., La Gruta, N., Purcell, A., Reid, H., Thomas, R. and Rossjohn, Jamie 2013. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine 210 (12) , pp. 2569-2582. 10.1084/jem.20131241 |
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Kasmar, A. G., Van Rhijn, I., Magalhaes, K. G., Young, D. C., Cheng, T.-Y., Turner, M. T., Schiefner, A., Kalathur, R. C., Wilson, I. A., Bhati, M., Gras, S., Birkinshaw, R. W., Tan, L. L., Rossjohn, Jamie, Shires, J., Jakobsen, S., Altman, J. D. and Moody, D. B. 2013. Cutting edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. The Journal of Immunology 191 (9) , pp. 4499-4503. 10.4049/jimmunol.1301660 |
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Valkenburg, S., Quiñones-Parra, S., Gras, S., Komadina, N., McVernon, J., Wang, Z., Halim, H., Iannello, P., Cole, C., Laurie, K., Kelso, A., Rossjohn, Jamie, Doherty, P., Turner, S. and Kedzierska, K. 2013. Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides. Nature Communications 4 (3663) 10.1038/ncomms3663 |
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Eckle, S. B., Turner, S. J., Rossjohn, Jamie and McCluskey, J. 2013. Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules? Current Opinion in Immunology 25 (5) , pp. 653-659. 10.1016/j.coi.2013.07.010 |
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Le Nours, J., Paton, A., Byres, E., Troy, S., Herdman, B., Johnson, M., Paton, J., Rossjohn, Jamie and Beddoe, T. 2013. Structural basis of subtilase cytotoxin subAB assembly. Journal of Biological Chemistry 288 (38) , pp. 27505-27516. 10.1074/jbc.M113.462622 |
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de Weerd, N., Vivian, J., Nguyen, T., Mangan, N., Gould, J., Braniff, S., Zaker-Tabrizi, L., Fung, K., Forster, S., Beddoe, T., Reid, H., Rossjohn, Jamie and Hertzog, P. 2013. Structural basis of a unique interferon-? signaling axis mediated via the receptor IFNAR1. Nature Immunology 14 (9) , pp. 901-907. 10.1038/ni.2667 |
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Ng, N., Littler, D., Le Nours, J., Paton, A., Paton, J., Rossjohn, Jamie and Beddoe, T. 2013. Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB5toxin. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 69 (8) , pp. 912-915. 10.1107/S1744309113018927 |
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Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S., Birkinshaw, R., Beddoe, T., Corbett, A., Liu, L., Miles, John James, Meehan, B., Reantragoon, R., Sandoval-Romero, M., Sullivan, L., Brooks, A., Chen, Z., Fairlie, D., McCluskey, J. and Rossjohn, Jamie 2013. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications 4 (2142) 10.1038/ncomms3142 |
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Van Rhijn, I., Kasmar, A., de Jong, A., Gras, S., Bhati, M., Doorenspleet, M., de Vries, N., Godfrey, D., Altman, J., de Jager, W., Rossjohn, Jamie and Moody, D. 2013. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nature Immunology 14 (7) , pp. 706-713. 10.1038/ni.2630 |
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Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland, A., Chen, Z., Sullivan, L. C., Burrows, J. M., Miles, John James, Brennan, R. M., Gras, S., Khanna, R., Brooks, A. G., McCluskey, J., Purcell, A. W., Rossjohn, Jamie and Burrows, S. R. 2013. HLA peptide length preferences control CD8+ T cell responses. The Journal of Immunology 191 (2) , pp. 561-571. 10.4049/jimmunol.1300292 |
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Liu, Y., Miles, John James, Neller, M., Gostick, E., Price, David, Purcell, A., McCluskey, J., Burrows, S., Rossjohn, Jamie and Gras, S. 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22) , pp. 15442-15454. 10.1074/jbc.M112.447185 |
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Berry, R., Ng, N., Saunders, P., Vivian, J., Lin, J., Deuss, F., Corbett, A., Forbes, C., Widjaja, J., Sullivan, L., McAlister, A., Perugini, M., Call, M., Scalzo, A., Degli-Esposti, M., Coudert, J., Beddoe, T., Brooks, A. and Rossjohn, Jamie 2013. Targeting of a natural killer cell receptor family by a viral immunoevasin. Nature Immunology 14 (7) , pp. 699-705. 10.1038/ni.2605 |
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Valkenburg, S., Gras, S., Guillonneau, C., Hatton, L., Bird, N., Twist, K., Halim, H., Jackson, D., Purcell, A., Turner, S, Doherty, P., Rossjohn, Jamie and Kedzierska, K. 2013. Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proceedings of the National Academy of Sciences of the United States of America 110 (14) , pp. 5570-5575. 10.1073/pnas.1302935110 |
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Ladell, Kristin Ingrid, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James Edward, Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie, Price, David and Appay, Victor 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3) , pp. 425-436. 10.1016/j.immuni.2012.11.021 |
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Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202 |
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Illing, P. T., Vivan, J. P., Rossjohn, Jamie and McCluskey, J. 2013. Human leukocyte antigen-associated drug hypersensitivity [review]. Current Opinion in Immunology 25 (1) , pp. 81-89. 10.1016/j.coi.2012.10.002 |
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Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David, Burrows, Scott R., Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202 |
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Eckle, Sidonia B. G., Rossjohn, Jamie and McCluskey, James 2013. Alloreactivity. In: Zachary, Andrea A. and Leffell, Mary S. eds. Transplantation Immunology, Vol. 1034. Methods in Molecular Biology, Springer, pp. 3-39. (10.1007/978-1-62703-493-7_1) |
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Uldrich, A., Le Nours, J., Pellicci, D., Gherardin, N., McPherson, K., Lim, R., Patel, O., Beddoe, T., Gras, S., Rossjohn, Jamie and Godfrey, D. 2013. CD1d-lipid antigen recognition by the γδTCR. Nature Immunology 14 (11) , pp. 1137-1145. 10.1038/ni.2713 |
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Vavassori, Stefano, Kumar, Anil, Wan, Gan Siok, Ramanjaneyulu, Gundimeda S., Cavallari, Marco, El Daker, Sary, Beddoe, Travis, Theodossis, Alex, Williams, Neal K., Gostick, Emma, Price, David, Soudamini, Dinish U., Voon, Kong Kien, Olivo, Malini, Rossjohn, Jamie, Mori, Lucia and De Libero, Gennaro 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9) , pp. 908-916. 10.1038/ni.2665 |
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Patel, Onisha, Pellicci, Daniel G., Gras, Stephanie, Sandoval-Romero, Maria L., Uldrich, Adam P., Mallevaey, Thierry, Clarke, Andrew J., Le Nours, Jérôme, Theodossis, Alex, Cardell, Susanna L., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie 2012. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nature Immunology 13 (9) , pp. 857-863. 10.1038/ni.2372 |
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Bulek, Anna, Cole, David, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John, Gostick, Emma, Price, David, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre and Sewell, Andrew 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206 |
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Vivian, Julian P., Duncan, Renee C., Berry, Richard, O'Connor, Geraldine M., Reid, Hugh H., Beddoe, Travis, Gras, Stephanie, Saunders, Philippa M., Olshina, Maya A., Widjaja, Jacqueline M. L., Harpur, Christopher M., Lin, Jie, Maloveste, Sebastien M., Price, David, Lafont, Bernard A. P., McVicar, Daniel W., Clements, Craig S., Brooks, Andrew G. and Rossjohn, Jamie 2011. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B [Letter]. Nature 479 (7373) , pp. 401-405. 10.1038/nature10517 |
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Pellicci, Daniel G., Clarke, Andrew J., Patel, Onisha, Mallevaey, Thierry, Beddoe, Travis, Le Nours, Jérôme, Uldrich, Adam P., McCluskey, James, Besra, Gurdyal S., Porcelli, Steven A., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie 2011. Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nature Immunology 12 (9) , pp. 827-833. 10.1038/ni.2076 |
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Iglesias, M. C., Almeida, J. R., Fastenackels, S., van Bockel, D. J., Hashimoto, M., Venturi, V., Gostick, E., Urrutia, A., Wooldridge, L., Clement, Mathew, Gras, S., Wilmann, P. G., Autran, B., Moris, A., Rossjohn, Jamie, Davenport, M. P., Takiguchi, M., Brander, C., Douek, D. C., Kelleher, A. D., Price, David and Appay, V. 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781 |
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Pang, Siew Siew, Berry, Richard, Chen, Zhenjun, Kjer-Nielsen, Lars, Perugini, Matthew A., King, Glenn F., Wang, Christina, Chew, Sock Hui, La Gruta, Nicole L., Williams, Neal K., Beddoe, Travis, Tiganis, Tony, Cowieson, Nathan P., Godfrey, Dale I., Purcell, Anthony W., Wilce, Matthew C. J., McCluskey, James and Rossjohn, Jamie 2010. The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature 467 (7317) , pp. 844-848. 10.1038/nature09448 |
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Beddoe, Travis, Chen, Zhenjun, Clements, Craig S., Ely, Lauren K., Bushell, Simon R., Vivian, Julian P., Kjer-Nielsen, Lars, Pang, Siew Siew, Dunstone, Michelle A., Liu, Yu Chih, Macdonald, Whitney A., Perugini, Matthew A., Wilce, Matthew C.J., Burrows, Scott R., Purcell, Anthony W., Tiganis, Tony, Bottomley, Stephen P., McCluskey, James and Rossjohn, Jamie 2009. Antigen ligation triggers a conformational change within the constant domain of the αβ T cell receptor. Immunity 30 (6) , pp. 777-788. 10.1016/j.immuni.2009.03.018 |
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