Browse by Current Cardiff authors

Awad, Wael, Ler, Geraldine J. M., Xu, Weijun, Keller, Andrew N., Mak, Jeffrey Y. W., Lim, Xin Yi, Liu, Ligong, Eckle, Sidonia B. G., Le Nours, Jérôme, McCluskey, James, Corbett, Alexandra J., Fairlie, David P. and Rossjohn, Jamie 2020. The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature Immunology 21 (4) , pp. 400-411. 10.1038/s41590-020-0616-6

McSharry, Brian P., Samer, Carolyn, McWilliam, Hamish E.G., Ashley, Caroline L., Yee, Michael B., Steain, Megan, Liu, Ligong, Fairlie, David P., Kinchington, Paul R., McCluskey, James, Abendroth, Allison, Villadangos, Jose A., Rossjohn, Jamie and Slobedman, Barry 2020. Virus-mediated suppression of the antigen presentation Molecule MR1. Cell Reports 30 (9) , 2948-2962e4. 10.1016/j.celrep.2020.02.017

Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara, Ager, Ann, Parker, Alan L., Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie, Svane, Inge Marie, Phillips, John D. and Sewell, Andrew K. 2020. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21 , pp. 178-185. 10.1038/s41590-019-0578-8 Item availability restricted.

Berry, Richard, Watson, Gabrielle M., Jonjic, Stipan, Degli-Esposti, Mariapia A. and Rossjohn, Jamie 2020. Modulation of innate and adaptive immunity by cytomegaloviruses. Nature Reviews Immunology 20 , pp. 113-127. 10.1038/s41577-019-0225-5

Rowntree, Louise C., van den Heuvel, Heleen, Sun, Jessica, D'Orsogna, Lloyd J., Nguyen, Thi H. O., Claas, Frans H. J., Rossjohn, Jamie, Kotsimbos, Tom C., Purcell, Anthony W. and Mifsud, Nicole A. 2020. Preferential HLA-B27 allorecognition displayed by multiple cross-reactive antiviral CD8+ T cell receptors. Frontiers in Immunology 11 , 248. 10.3389/fimmu.2020.00248

Ting, Yi Tian, Dahal-Koirala, Shiva, Kim, Hui Shi Keshia, Qiao, Shuo-Wang, Neumann, Ralf S., Lundin, Knut E. A., Petersen, Jan, Reid, Hugh H., Sollid, Ludvig M. and Rossjohn, Jamie 2020. A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease. Proceedings of the National Academy of Sciences 117 (6) , pp. 3063-3073. 10.1073/pnas.1914308117

Petersen, Jan, Ciacchi, Laura, Tran, Mai T., Loh, Khai Lee, Kooy-Winkelaar, Yvonne, Croft, Nathan P., Hardy, Melinda Y., Chen, Zhenjun, McCluskey, James, Anderson, Robert P., Purcell, Anthony W., Tye-Din, Jason A., Koning, Frits, Reid, Hugh H. and Rossjohn, Jamie 2020. T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nature Structural and Molecular Biology 27 (1) , pp. 49-61. 10.1038/s41594-019-0353-4 Item availability restricted.

Nicolai, Sarah, Wegrecki, Marcin, Cheng, Tan-Yun, Bourgeois, Elvire A., Cotton, Rachel N., Mayfield, Jacob A., Monnot, Gwennaëlle C., Le Nours, Jérôme, Van Rhijn, Ildiko, Rossjohn, Jamie, Moody, D. Branch and de Jong, Annemieke 2020. Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Science Immunology 5 (43) , eaax5430. 10.1126/sciimmunol.aax5430 Item availability restricted.

Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Koay, Hui-Fern, Meehan, Bronwyn, Zhao, Zhe, Pediongco, Troi, Shi, Mai, Zhu, Tianyuan, Wang, Bingjie, Kjer-Nielsen, Lars, Eckle, Sidonia B. G., Rossjohn, Jamie, Fairlie, David P., Godfrey, Dale I., Strugnell, Richard A., McCluskey, James and Corbett, Alexandra J. 2019. Characterization and purification of mouse mucosal-associated invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e89. 10.1002/cpim.89

Souter, Michael N.T., Loh, Liyen, Li, Shihan, Meehan, Bronwyn S., Gherardin, Nicholas A., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., Kedzierska, Katherine, Pellicci, Daniel G., Chen, Zhenjun, Kjer-Nielsen, Lars, Corbett, Alexandra J., McCluskey, James and Eckle, Sidonia B. G. 2019. Characterization of Human Mucosal-associated Invariant T (MAIT) cells. Current Protocols in Immunology 127 (1) , e90. 10.1002/cpim.90

Picarda, Elodie, Bézie, Séverine, Usero, Lorena, Ossart, Jason, Besnard, Marine, Halim, Hanim, Echasserieau, Klara, Usal, Claire, Rossjohn, Jamie, Bernardeau, Karine, Gras, Stéphanie and Guillonneau, Carole 2019. Cross-reactive donor-specific CD8+ Tregs efficiently prevent transplant rejection. Cell Reports 29 (13) , 4245-4255.e6. 10.1016/j.celrep.2019.11.106

Le Nours, Jérôme, Gherardin, Nicholas A., Ramarathinam, Sri H., Awad, Wael, Wiede, Florian, Gully, Benjamin S., Khandokar, Yogesh, Praveena, T., Wubben, Jacinta M., Sandow, Jarrod J., Webb, Andrew I., von Borstel, Anouk, Rice, Michael T., Redmond, Samuel J., Seneviratna, Rebecca, Sandoval-Romero, Maria L., Li, Shihan, Souter, Michael N. T., Eckle, Sidonia B. G., Corbett, Alexandra J., Reid, Hugh H., Liu, Ligong, Fairlie, David P., Giles, Edward M., Westall, Glen P., Tothill, Richard W., Davey, Martin S., Berry, Richard, Tiganis, Tony, McCluskey, James, Pellicci, Daniel G., Purcell, Anthony W., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie 2019. A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science 366 (6472) , pp. 1522-1527. 10.1126/science.aav3900

Reinink, Peter, Shahine, Adam, Gras, Stephanie, Cheng, Tan-Yun, Farquhar, Rachel, Lopez, Kattya, Suliman, Sara A., Reijneveld, Josephine F., Le Nours, Jérôme, Tan, Li Lynn, León, Segundo R., Jimenez, Judith, Calderon, Roger, Lecca, Leonid, Murray, Megan B., Rossjohn, Jamie, Moody, D. Branch and Van Rhijn, Ildiko 2019. A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins. Journal of Immunology 203 (12) , pp. 3395-3046. 10.4049/jimmunol.1900872

van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J., Nguyen, T. H. O., Gras, S., Chen, W. and Kedzierska, K. 2019. Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph. Nature Communications 10 (1) , 5579. 10.1038/s41467-019-13346-4

Almeida, Catarina F., Sundararaj, Srinivasan, Le Nours, Jérôme, Praveena, T., Cao, Benjamin, Burugupalli, Satvika, Smith, Dylan G. M., Patel, Onisha, Brigl, Manfred, Pellicci, Daniel G., Williams, Spencer J., Uldrich, Adam P., Godfrey, Dale I. and Rossjohn, Jamie 2019. Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nature Communications 10 (1) , 5242. 10.1038/s41467-019-12941-9

Wang, Huimeng, Kjer-Nielsen, Lars, Shi, Mai, D?Souza, Criselle, Pediongco, Troi J., Cao, Hanwei, Kostenko, Lyudmila, Lim, Xin Yi, Eckle, Sidonia B. G., Meehan, Bronwyn S., Zhu, Tianyuan, Wang, Bingjie, Zhao, Zhe, Mak, Jeffrey Y. W., Fairlie, David P., Teng, Michele W. L., Rossjohn, Jamie, Yu, Di, de St Groth, Barbara Fazekas, Lovrecz, George, Lu, Louis, McCluskey, James, Strugnell, Richard A., Corbett, Alexandra J. and Chen, Zhenjun 2019. IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology 4 (41) , eaaw0402. 10.1126/sciimmunol.aaw0402

Deuss, Felix A., Watson, Gabrielle M., Goodall, Katharine J., Leece, Isobel, Chatterjee, Sayantani, Fu, Zhihui, Thaysen-Andersen, Morten, Andrews, Daniel M., Rossjohn, Jamie and Berry, Richard 2019. Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1. Journal of Biological Chemistry 294 (33) , pp. 12534-12546. 10.1074/jbc.RA119.009261 Item availability restricted.

Niehrs, Annika, Garcia-Beltran, Wilfredo F., Norman, Paul J., Watson, Gabrielle M., Hölzemer, Angelique, Chapel, Anaïs, Richert, Laura, Pommerening-Röser, Andreas, Körner, Christian, Ozawa, Mikki, Martrus, Glòria, Rossjohn, Jamie, Lee, Jar-How, Berry, Richard, Carrington, Mary and Altfeld, Marcus 2019. A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44. Nature Immunology 20 (9) , pp. 1129-1137. 10.1038/s41590-019-0448-4

Schinkelshoek, M.S., Fronczek, R., Kooy-Winkelaar, E.M.C., Petersen, J., Reid, H.H., van der Heide, A., Drijfhout, J.W., Rossjohn, Jamie, Lammers, G.J. and Koning, F. 2019. H1N1 hemagglutinin-specific HLA-DQ6-restricted CD4+ T cells can be readily detected in narcolepsy type 1 patients and healthy controls. Journal of Neuroimmunology 332 , pp. 167-175. 10.1016/j.jneuroim.2019.04.009

Koutsakos, Marios, McWilliam, Hamish E. G., Aktepe, Turgut E., Fritzlar, Svenja, Illing, Patricia T., Mifsud, Nicole A., Purcell, Anthony W., Rockman, Steve, Reading, Patrick C., Vivian, Julian P., Rossjohn, Jamie, Brooks, Andrew G., Mackenzie, Jason M., Mintern, Justine D., Villadangos, Jose A., Nguyen, Thi H. O. and Kedzierska, Katherine 2019. Downregulation of MHC class I expression by influenza A and B viruses. Frontiers in Immunology 10 , -. 10.3389/fimmu.2019.01158

Koutsakos, Marios, Illing, Patricia T., Nguyen, Thi H. O., Mifsud, Nicole A., Crawford, Jeremy Chase, Rizzetto, Simone, Eltahla, Auda A., Clemens, E. Bridie, Sant, Sneha, Chua, Brendon Y., Wong, Chinn Yi, Allen, E. Kaitlynn, Teng, Don, Dash, Pradyot, Boyd, David F., Grzelak, Ludivine, Zeng, Weiguang, Hurt, Aeron C., Barr, Ian, Rockman, Steve, Jackson, David C., Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Wakim, Linda M., Rossjohn, Jamie, Vijaykrishna, Dhanasekaran, Luciani, Fabio, Thomas, Paul G., Gras, Stephanie, Purcell, Anthony W. and Kedzierska, Katherine 2019. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nature Immunology 20 , pp. 613-625. 10.1038/s41590-019-0320-6

Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt 2019. A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical 284 , pp. 281-288. 10.1016/j.snb.2018.12.099

Mayassi, Toufic, Ladell, Kristin, Gudjonson, Herman, McLaren, James, Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie, Price, David A. and Jabri, Bana 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176 (5) , pp. 967-981. 10.1016/j.cell.2018.12.039

Neier, Steven C., Ferrer, Alejandro, Wilton, Katelynn M., Smith, Stephen E. P., Kelcher, April M. H., Pavelko, Kevin D., Canfield, Jenna M., Davis, Tessa R., Stiles, Robert J., Chen, Zhenjun, McCluskey, James, Burrows, Scott R., Rossjohn, Jamie, Hebrink, Deanne M., Carmona, Eva M., Limper, Andrew H., Kappes, Dietmar J., Wettstein, Peter J., Johnson, Aaron J., Pease, Larry R., Daniels, Mark A., Neuhauser, Claudia, Gil, Diana and Schrum, Adam G. 2019. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology 4 (32) , eaal2201. 10.1126/sciimmunol.aal2201

Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E. A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie and Sollid, Ludvig M. 2019. Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes. Journal of Biological Chemistry 294 (3) , pp. 941-952. 10.1074/jbc.RA118.005736

Shahine, Adam, Reinink, Peter, Reijneveld, Josephine F., Gras, Stephanie, Holzheimer, Mira, Cheng, Tan-Yun, Minnaard, Adriaan J., Altman, John D., Lenz, Steffi, Prandi, Jacques, Kubler-Kielb, Joanna, Moody, D. Branch, Rossjohn, Jamie and Van Rhijn, Ildiko 2019. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nature Communications 10 (1) , -. 10.1038/s41467-018-07898-0

Ooi, Joshua D., Jiang, Jhih-Hang, Eggenhuizen, Peter J., Chua, Ling L., van Timmeren, Mirjan, Loh, Khai L., O?Sullivan, Kim M., Gan, Poh Y., Zhong, Yong, Tsyganov, Kirill, Shochet, Lani R., Ryan, Jessica, Stegeman, Coen A., Fugger, Lars, Reid, Hugh H., Rossjohn, Jamie, Heeringa, Peter, Holdsworth, Stephen R., Peleg, Anton Y. and Kitching, A. Richard 2019. A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity. Nature Communications 10 (1) , 3392. 10.1038/s41467-019-11255-0

Grant, Emma J., Josephs, Tracy M., Loh, Liyen, Clemens, E. Bridie, Sant, Sneha, Bharadwaj, Mandvi, Chen, Weisan, Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine 2018. Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans. Nature Communications 9 (1) , -. 10.1038/s41467-018-07815-5

Gherardin, Nicholas A., McCluskey, James, Rossjohn, Jamie and Godfrey, Dale I. 2018. The diverse family of MR1-restricted T cells. The Journal of Immunology 201 (10) , pp. 2862-2871. 10.4049/jimmunol.1801091

Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P. and Purcell, Anthony W. 2018. HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature Communications 9 (1) , 4693. 10.1038/s41467-018-07109-w

Balaji, Gautham R., Aguilar, Oscar A., Tanaka, Miho, Shingu-Vazquez, Miguel A., Fu, Zhihui, Gully, Benjamin S., Lanier, Lewis L., Carlyle, James R., Rossjohn, Jamie and Berry, Richard 2018. Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition. Nature Communications 9 (1) , 4623. 10.1038/s41467-018-06989-2

Faridi, Pouya, Li, Chen, Ramarathinam, Sri H., Vivian, Julian P., Illing, Patricia T., Mifsud, Nicole A., Ayala, Rochelle, Song, Jiangning, Gearing, Linden J., Hertzog, Paul J., Ternette, Nicola, Rossjohn, Jamie, Croft, Nathan P. and Purcell, Anthony W. 2018. A subset of HLA-I peptides are not genomically templated: evidence for cis- and trans-spliced peptide ligands. Science Immunology 3 (28) , eaar3947. 10.1126/sciimmunol.aar3947

Robson, Kate J., Ooi, Joshua D., Holdsworth, Stephen R., Rossjohn, Jamie and Kitching, A. Richard 2018. HLA and kidney disease: from associations to mechanisms. Nature Reviews Nephrology 14 (10) , pp. 636-655. 10.1038/s41581-018-0057-8

O'Donnell, Valerie, Rossjohn, Jamie and Wakelam, M. J. O. 2018. Phospholipid signaling in innate immune cells. The Journal of Clinical Investigation 128 (7) , pp. 2670-2679. 10.1172/JCI97944

Awad, Wael, Le Nours, Jérôme, Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie 2018. Mucosal-associated invariant T cell receptor recognition of small molecules presented by MR1. Immunology and Cell Biology 96 (6) , pp. 588-597. 10.1111/imcb.12017

Kjer-Nielsen, Lars, Corbett, Alexandra J., Chen, Zhenjun, Liu, Ligong, Mak, Jeffrey Y. W., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., McCluskey, James and Eckle, Sidonia B. G. 2018. An overview on the identification of MAIT cell antigens. Immunology and Cell Biology 96 (6) , pp. 573-587. 10.1111/imcb.12057

La Gruta, Nicole L., Gras, Stephanie, Daley, Stephen R., Thomas, Paul G. and Rossjohn, Jamie 2018. Understanding the drivers of MHC restriction of T cell receptors. Nature Reviews Immunology 18 , pp. 467-478. 10.1038/s41577-018-0007-5

Sant, Sneha, Grzelak, Ludivine, Wang, Zhongfang, Pizzolla, Angela, Koutsakos, Marios, Crowe, Jane, Loudovaris, Thomas, Mannering, Stuart I., Westall, Glen P., Wakim, Linda M., Rossjohn, Jamie, Gras, Stephanie, Richards, Michael, Xu, Jianqing, Thomas, Paul G., Loh, Liyen, Nguyen, Thi H. O. and Kedzierska, Katherine 2018. Single-cell approach to influenza-specific CD8+ T Cell receptor repertoires across different age groups, tissues, and following influenza virus infection. Frontiers in Immunology 9 , 1453. 10.3389/fimmu.2018.01453

Rowntree, Louise C., Nguyen, Thi H. O., Halim, Hanim, Purcell, Anthony W., Rossjohn, Jamie, Gras, Stephanie, Kotsimbos, Tom C. and Mifsud, Nicole A. 2018. Inability to detect cross-reactive memory T cells challenges the frequency of heterologous immunity among common viruses. Journal of Immunology 200 (12) , pp. 3993-4003. 10.4049/jimmunol.1800010

Cotton, Rachel N, Shahine, Adam, Rossjohn, Jamie and Moody, D Branch 2018. Lipids hide or step aside for CD1-autoreactive T cell receptors. Current Opinion in Immunology 52 , pp. 93-99. 10.1016/j.coi.2018.04.013

Ramarathinam, Sri H., Gras, Stephanie, Alcantara, Sheilajen, Yeung, Amanda W.S., Mifsud, Nicole A., Sonza, Secondo, Illing, Patricia T., Glaros, Elias N., Center, Robert J., Thomas, Shane, Kent, Stephen J., Ternette, Nicola, Purcell, Damian F. J., Rossjohn, Jamie and Purcell, Anthony W. 2018. Identification of native and post-translationally modified HLA-B*57:01-restricted HIV envelope derived epitopes using immunoproteomics. PROTEOMICS 18 (12) , 1700253. 10.1002/pmic.201700253

Chennamadhavuni, Divya, Saavedra-Avila, Noemi Alejandra, Carreño, Leandro J., Guberman-Pfeffer, Matthew J., Arora, Pooja, Yongqing, Tang, Koay, Hui-Fern, Godfrey, Dale I., Keshipeddy, Santosh, Richardson, Stewart K., Sundararaj, Srinivasan, Lo, Jae Ho, Wen, Xiangshu, Gascón, José A., Yuan, Weiming, Rossjohn, Jamie, Le Nours, Jérôme, Porcelli, Steven A. and Howell, Amy R. 2018. Dual modifications of α-Galactosylceramide Synergize to promote activation of human invariant natural killer T cells and stimulate anti-tumor immunity. Cell Chemical Biology 25 (5) , pp. 571-584. 10.1016/j.chembiol.2018.02.009

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y.W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill., Geoffrey R. 2018. Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation 128 (5) , pp. 1919-1936. 10.1172/JCI91646

Dendrou, Calliope A., Petersen, Jan, Rossjohn, Jamie and Fugger, Lars 2018. HLA variation and disease. Nature Reviews Immunology 18 , pp. 325-339. 10.1038/nri.2017.143

Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A., Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie, Brooks, Andrew G. and Carrington, Mary 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5) , p. 1903. 10.1172/JCI98463

Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J., Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew, Makinde, Julia, Ladell, Kristin, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne, Attaf, Meriem, Lissina, Anya, Ager, Ann, Gallimore, Awen, Rizkallah, Pierre J., Gras, Stephanie, Rossjohn, Jamie, Burrows, Scott R., Cole, David K., Price, David A. and Sewell, Andrew K. 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. The Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512

Godfrey, Dale I., Le Nours, Jérôme, Andrews, Daniel M., Uldrich, Adam P. and Rossjohn, Jamie 2018. Unconventional T cell targets for cancer immunotherapy. Immunity 48 (3) , pp. 453-473. 10.1016/j.immuni.2018.03.009

Chan, Kok Fei, Gully, Benjamin S., Gras, Stephanie, Beringer, Dennis X., Kjer-Nielsen, Lars, Cebon, Jonathan, McCluskey, James, Chen, Weisan and Rossjohn, Jamie 2018. Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nature Communications 9 , 1026. 10.1038/s41467-018-03321-w

Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E., Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A., Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp. 397-406. 10.1038/s41590-018-0065-7

Ting, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie 2018. The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. Journal of Biological Chemistry 293 (9) , pp. 3236-3251. 10.1074/jbc.RA117.001013

D'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. 2018. Mucosal-associated invariant T cells augment immunopathology and gastritis in chronic helicobacter pyloriInfection. The Journal of Immunology 200 (5) , pp. 1901-1916. 10.4049/jimmunol.1701512 Item availability restricted.

Sundararaj, Srinivasan, Zhang, Jingjing, Krovi, S. Harsha, Bedel, Romain, Tuttle, Kathryn D., Veerapen, Natacha, Besra, Gurdyal S., Khandokar, Yogesh, Praveena, T., Le Nours, Jérôme, Matsuda, Jennifer L., Rossjohn, Jamie and Gapin, Laurent 2018. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proceedings of the National Academy of Sciences 115 (6) , E1204-E1213. 10.1073/pnas.1716669115

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny 2018. Flow cytometric clinical immunomonitoring using peptide-MHC class II tetramers: optimization of methods and protocol development. Frontiers in Immunology 9 , 8. 10.3389/fimmu.2018.00008

Galperin, Moran, Farenc, Carine, Mukhopadhyay, Madhura, Jayasinghe, Dhilshan, Decroos, Amandine, Benati, Daniela, Tan, Li Lynn, Ciacchi, Lisa, Reid, Hugh H., Rossjohn, Jamie, Chakrabarti, Lisa A. and Gras, Stephanie 2018. CD4+ T cell–mediated HLA class II cross-restriction in HIV controllers. Science Immunology 3 (24) , eaat0687. 10.1126/sciimmunol.aat0687

Wang, Huimeng, D'Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun 2018. MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications 9 (1) , 3350. 10.1038/s41467-018-05202-8

Sullivan, Lucy C., Walpole, Nicholas G., Farenc, Carine, Pietra, Gabriella, Sum, Matthew J. W., Clements, Craig S., Lee, Eleanor J., Beddoe, Travis, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, Gras, Stephanie, Rossjohn, Jamie and Brooks, Andrew G. 2017. A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors. Journal of Biological Chemistry 292 (51) , pp. 21149-21158. 10.1074/jbc.M117.807719

Cook, Laura, Munier, C. Mee Ling, Seddiki, Nabila, van Bockel, David, Ontiveros, Noé, Hardy, Melinda Y., Gillies, Jana K., Levings, Megan K., Reid, Hugh H., Petersen, Jan, Rossjohn, Jamie, Anderson, Robert P., Zaunders, John J., Tye-Din, Jason A. and Kelleher, Anthony D. 2017. Circulating gluten-specific FOXP3 + CD39 + regulatory T cells have impaired suppressive function in patients with celiac disease. Journal of Allergy and Clinical Immunology 140 (6) , pp. 1592-1603. 10.1016/j.jaci.2017.02.015

Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly, Farenc, Carine, Price, David, Rossjohn, Jamie and Harty, John T. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5) , 835-847.e4. 10.1016/j.immuni.2017.10.013

Scally, Stephen W, Law, Soi-Cheng, Ting, Yi Tian, Heemst, Jurgen van, Sokolove, Jeremy, Deutsch, Aaron J, Bridie Clemens, E, Moustakas, Antonis K, Papadopoulos, George K, Woude, Diane van der, Smolik, Irene, Hitchon, Carol A, Robinson, David B, Ferucci, Elizabeth D, Bernstein, Charles N, Meng, Xiaobo, Anaparti, Vidyanand, Huizinga, Tom, Kedzierska, Katherine, Reid, Hugh H, Raychaudhuri, Soumya, Toes, René E, Rossjohn, Jamie, El-Gabalawy, Hani and Thomas, Ranjeny 2017. Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Annals of the Rheumatic Diseases 76 (11) , pp. 1915-1923. 10.1136/annrheumdis-2017-211300

Culshaw, Abigail, Ladell, Kristin, Gras, Stephanie, McLaren, James, Miners, Kelly, Farenc, Carine, van den Heuvel, Heleen, Gostick, Emma, Dejnirattisai, Wanwisa, Wangteeraprasert, Apirath, Duangchinda, Thaneeya, Chotiyarnwong, Pojchong, Limpitikul, Wannee, Vasanawathana, Sirijitt, Malasit, Prida, Dong, Tao, Rossjohn, Jamie, Mongkolsapaya, Juthathip, Price, David A. and Screaton, Gavin R. 2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18 , pp. 1228-1237. 10.1038/ni.3850

Mobbs, Jesse I., Illing, Patricia T., Dudek, Nadine L., Brooks, Andrew G., Baker, Daniel G., Purcell, Anthony W., Rossjohn, Jamie and Vivian, Julian P. 2017. The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C*06:02 molecule. Journal of Biological Chemistry 292 (42) , pp. 17203-17215. 10.1074/jbc.M117.806976

Shahine, Adam, Van Rhijn, Ildiko, Cheng, Tan-Yun, Iwany, Sarah, Gras, Stephanie, Moody, D. Branch and Rossjohn, Jamie 2017. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Science Immunology 2 (16) , eaao1384. 10.1126/sciimmunol.aao1384

Rouxel, Ophélie, Da silva, Jennifer, Beaudoin, Lucie, Nel, Isabelle, Tard, Céline, Cagninacci, Lucie, Kiaf, Badr, Oshima, Masaya, Diedisheim, Marc, Salou, Marion, Corbett, Alexandra, Rossjohn, Jamie, McCluskey, James, Scharfmann, Raphael, Battaglia, Manuela, Polak, Michel, Lantz, Olivier, Beltrand, Jacques and Lehuen, Agnès 2017. Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes. Nature Immunology 18 (12) , pp. 1321-1331. 10.1038/ni.3854

Littler, Dene R., Ang, Sheng Y., Moriel, Danilo G., Kocan, Martina, Kleifeld, Oded, Johnson, Matthew D., Tran, Mai T., Paton, Adrienne W., Paton, James C., Summers, Roger J., Schembri, Mark A., Rossjohn, Jamie and Beddoe, Travis 2017. Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins. Journal of Biological Chemistry 292 (36) , pp. 15143-15158. 10.1074/jbc.M117.796094

Brennan, Patrick J., Cheng, Tan-Yun, Pellicci, Daniel G., Watts, Gerald F. M., Veerapen, Natacha, Young, David C., Rossjohn, Jamie, Besra, Gurdyal S., Godfrey, Dale I., Brenner, Michael B. and Moody, D. Branch 2017. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proceedings of the National Academy of Sciences of the United States of America 114 (31) , pp. 8348-8353. 10.1073/pnas.1705882114

Deuss, Felix A., Gully, Benjamin S., Rossjohn, Jamie and Berry, Richard 2017. Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT). Journal of Biological Chemistry 292 (27) , pp. 11413-11422. 10.1074/jbc.M117.786483

Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie and Fugger, Lars 2017. Structural and regulatory diversity shape HLA-C protein expression levels. Nature Communications 8 , p. 15924. 10.1038/ncomms15924

Shaler, Christopher R., Choi, Joshua, Rudak, Patrick T., Memarnejadian, Arash, Szabo, Peter A., Tun-Abraham, Mauro E., Rossjohn, Jamie, Corbett, Alexandra J., McCluskey, James, McCormick, John K., Lantz, Olivier, Hernandez-Alejandro, Roberto and Haeryfar, S.M. Mansour 2017. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLoS Biology 15 (6) , e2001930. 10.1371/journal.pbio.2001930

Ooi, Joshua D., Petersen, Jan, Tan, Yu H., Huynh, Megan, Willett, Zoe J., Ramarathinam, Sri H., Eggenhuizen, Peter J., Loh, Khai L., Watson, Katherine A., Gan, Poh Y., Alikhan, Maliha A., Dudek, Nadine L., Handel, Andreas, Hudson, Billy G., Fugger, Lars, Power, David A., Holt, Stephen G., Coates, P. Toby, Gregersen, Jon W., Purcell, Anthony W., Holdsworth, Stephen R., La Gruta, Nicole L., Reid, Hugh H., Rossjohn, Jamie and Kitching, A. Richard 2017. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature 545 (7653) , pp. 243-247. 10.1038/nature22329

De Weerd, Nicola A., Matthews, Anthony Y., Pattie, Philip R., Bourke, Nollaig M., Lim, San S., Vivian, Julian P., Rossjohn, Jamie and Hertzog, Paul J. 2017. A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling. World Journal of Biological Chemistry 292 , pp. 7554-7565. 10.1074/jbc.M116.773788

Keller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie 2017. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology 18 (4) , pp. 402-411. 10.1038/ni.3679

Pymm, Phillip, Illing, Patricia T, Ramarathinam, Sri H, O'Connor, Geraldine M, Hughes, Victoria A, Hitchen, Corinne, Price, David, Ho, Bosco K, McVicar, Daniel W, Brooks, Andrew G, Purcell, Anthony W, Rossjohn, Jamie and Vivian, Julian P 2017. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nature Structural & Molecular Biology 24 (4) , pp. 387-394. 10.1038/nsmb.3381

Aguilar, Oscar A., Berry, Richard, Rahim, Mir Munir A., Reichel, Johanna J., Popović, Branka, Tanaka, Miho, Fu, Zhihui, Balaji, Gautham R., Lau, Timothy N.H., Tu, Megan M., Kirkham, Christina L., Mahmoud, Ahmad Bakur, Mesci, Aruz, Krmpotić, Astrid, Allan, David S.J., Makrigiannis, Andrew P., Jonjić, Stipan, Rossjohn, Jamie and Carlyle, James R. 2017. A viral immunoevasin controls innate immunity by targeting the prototypical natural killer cell receptor family. Cell 169 (1) , pp. 58-71. 10.1016/j.cell.2017.03.002

Mak, Jeffrey Y. W., Xu, Weijun, Reid, Robert C., Corbett, Alexandra J., Meehan, Bronwyn S., Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong and Fairlie, David P. 2017. Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells. Nature Communications 8 , 14599. 10.1038/ncomms14599

Cheng, Janice M. H., Liu, Ligong, Pellicci, Daniel G., Reddiex, Scott J. J., Cotton, Rachel N., Cheng, Tan-Yun, Young, David C., Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Fairlie, David P., Godfrey, Dale I. and Williams, Spencer J. 2017. Total synthesis of Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition. Chemistry - A European Journal 23 (7) , pp. 1694-1701. 10.1002/chem.201605287

Chen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, S. B. G., Meehan, B. S., Jackson, D. C., Strugnell, R. A., Cao, H., Wang, N., Fairlie, D. P., Liu, L., Godfrey, D. I., Rossjohn, Jamie, McCluskey, J. and Corbett, A. J. 2017. Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals. Mucosal Immunology 10 (1) , pp. 58-68. 10.1038/mi.2016.39

Littler, Dene R., Bullen, Hayley E., Harvey, Katherine L., Beddoe, Travis, Crabb, Brendan S., Rossjohn, Jamie and Gilson, Paul R. 2016. Disrupting the allosteric interaction between the plasmodium falciparumcAMP-dependent kinase and its regulatory subunit. Journal of Biological Chemistry 291 (49) , p. 25375. 10.1074/jbc.M116.750174

Grant, Emma J., Josephs, Tracy M., Valkenburg, Sophie A., Wooldridge, Linda, Hellard, Margaret, Rossjohn, Jamie, Bharadwaj, Mandvi, Kedzierska, Katherine and Gras, Stephanie 2016. Lack of heterologous cross-reactivity toward HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures. Journal of Biological Chemistry 291 (47) , pp. 24335-24351. 10.1074/jbc.M116.753988

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Nicovich, Philip R., Bridgeman, John S., Cohnen, Andre, Benzing, Carola, Gao, Yijun, Crowther, Michael D., Tungatt, Katie, Dolton, Garry, Sewell, Andrew K., Price, David A., Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jeremie, Rossjohn, Jamie and Gaus, Katharina 2016. Correction for Pageon et al., functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (44) , E6905-E6905. 10.1073/pnas.1615763113

De Weerd, N. A., Matthews, A., Lim, S. S., Pattie, P., Bourke, N., Vivian, J. P., Rossjohn, Jamie and Hertzog, P. J. 2016. P140: Understanding the IFNÂ-IFNAR1 interface: implications for drug discovery in IFNÂ-DRIVEN disease [Poster Abstract]. Cytokine 87 , p. 120. 10.1016/j.cyto.2016.07.021

Koay, Hui-Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Mackay, Laura K., Almeida, Catarina F., Russ, Brendan E., Nold-Petry, Claudia A., Nold, Marcel F., Bedoui, Sammy, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Sidonia B. G., Meehan, Bronwyn, d'Udekem, Yves, Konstantinov, Igor E., Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Chong, Mark M., Kedzierska, Katherine, Berzins, Stuart P., Belz, Gabrielle T., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Pellicci, Daniel G. 2016. A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nature Immunology 17 (11) , pp. 1300-1311. 10.1038/ni.3565

Gras, Stephanie, Van Rhijn, Ildiko, Shahine, Adam, Cheng, Tan-Yun, Bhati, Mugdha, Tan, Li Lynn, Halim, Hanim, Tuttle, Kathryn D., Gapin, Laurent, Le Nours, Jerome, Moody, D. Branch and Rossjohn, Jamie 2016. T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nature Communications 7 , 13257. 10.1038/ncomms13257

Jaafar, Nardiah Rizwana, Littler, Dene, Beddoe, Travis, Rossjohn, Jamie, Illias, Rosli Md, Mahadi, Nor Muhammad, Mackeen, Mukram Mohamed, Murad, Abdul Munir Abdul and Abu Bakar, Farah Diba 2016. Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeastGlaciozyma antarctica PI12. Acta Crystallographica Section F Structural Biology Communications 72 (11) , pp. 831-839. 10.1107/S2053230X16015612

Gras, Stephanie, Chadderton, Jesseka, Del Campo, Claudia M., Farenc, Carine, Wiede, Florian, Josephs, Tracy M., Sng, Xavier Y. X., Mirams, Michiko, Watson, Katherine A., Tiganis, Tony, Quinn, Kylie M., Rossjohn, Jamie and La Gruta, Nicole L. 2016. Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response. Immunity 45 (4) , pp. 749-760. 10.1016/j.immuni.2016.09.007

Petersen, Jan, Kooy-Winkelaar, Yvonne, Loh, Khai Lee, Tran, Mai, van Bergen, Jeroen, Koning, Frits, Rossjohn, Jamie and Reid, Hugh H. 2016. Diverse T cell receptor gene usage in HLA-DQ8-associated celiac disease converges into a consensus binding solution. Structure 24 (10) , pp. 1643-1657. 10.1016/j.str.2016.07.010

Kim, Ji Hyung, Hu, Yu, Yongqing, Tang, Kim, Jessica, Hughes, Victoria A., Le Nours, Jerome, Marquez, Elsa A., Purcell, Anthony W., Wan, Qi, Sugita, Masahiko, Rossjohn, Jamie and Winau, Florian 2016. CD1a on Langerhans cells controls inflammatory skin disease. Nature Immunology 17 (10) , pp. 1159-1166. 10.1038/ni.3523

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Bridgeman, John S, Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D, Tungatt, Katie, Dolton, Garry, Sewell, Andrew, Price, David A, Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (37) , E5454-E5463. 10.1073/pnas.1607436113

Loh, Liyen, Wang, Zhongfang, Sant, Sneha, Koutsakos, Marios, Jegaskanda, Sinthujan, Corbett, Alexandra J., Liu, Ligong, Fairlie, David P., Crowe, Jane, Rossjohn, Jamie, Xu, Jianqing, Doherty, Peter C., McCluskey, James and Kedzierska, Katherine 2016. Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation. Proceedings of the National Academy of Sciences 113 (36) , pp. 10133-10138. 10.1073/pnas.1610750113

Sullivan, Lucy C., Berry, Richard, Sosnin, Natasha, Widjaja, Jacqueline M. L., Deuss, Felix A., Balaji, Gautham R., LaGruta, Nicole L., Mirams, Michiko, Trapani, Joseph A., Rossjohn, Jamie, Brooks, Andrew G. and Andrews, Daniel M. 2016. Recognition of the Major Histocompatibility Complex (MHC) class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C. Journal of Biological Chemistry 291 (36) , pp. 18740-18752. 10.1074/jbc.M116.737130

Cole, David, Bulek, Anna Marta, Dolton, Garry Michael, Schauenberg, Andrea J., Szomolay, Barbara, Rittase, William, Trimby, Andrew, Jothikumar, Prithiviraj, Fuller, Anna, Skowera, Ania, Rossjohn, Jamie, Zhu, Cheng, Miles, John J., Peakman, Mark, Wooldridge, Linda, Rizkallah, Pierre and Sewell, Andrew K. 2016. Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. Journal of Clinical Investigation 126 (6) , pp. 2191-2204. 10.1172/JCI85679

Jönsson, Peter, Southcombe, Jennifer H., Santos, Ana Mafalda, Huo, Jiandong, Fernandes, Ricardo A., McColl, James, Lever, Melissa, Evans, Edward J., Hudson, Alexander, Chang, Veronica T., Hanke, Tomá?, Godkin, Andrew, Dunne, Paul D., Horrocks, Mathew H., Palayret, Matthieu, Screaton, Gavin R., Petersen, Jan, Rossjohn, Jamie, Fugger, Lars, Dushek, Omer, Xu, Xiao-Ning, Davis, Simon J. and Klenerman, David 2016. Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions. Proceedings of the National Academy of Sciences of the United States of America 113 (20) , pp. 5682-5687. 10.1073/pnas.1513918113

Vinton, Carol, Wu, Fan, Rossjohn, Jamie, Matsuda, Kenta, McCluskey, James, Hirsch, Vanessa, Price, David, Brenchley, Jason M. and Silvestri, G. 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9) , pp. 4520-4529. 10.1128/JVI.02876-15

Benati, Daniela, Galperin, Moran, Lambotte, Olivier, Gras, Stéphanie, Lim, Annick, Mukhopadhyay, Madhura, Nouël, Alexandre, Campbell, Kristy-Anne, Lemercier, Brigitte, Claireaux, Mathieu, Hendou, Samia, Lechat, Pierre, de Truchis, Pierre, Boufassa, Faroudy, Rossjohn, Jamie, Delfraissy, Jean-François, Arenzana-Seisdedos, Fernando and Chakrabarti, Lisa A. 2016. Public T cell receptors confer high-avidity CD4 responses to HIV controllers. The Journal of Clinical Investigation 126 (6) , pp. 2093-2108. 10.1172/JCI83792

Valkenburg, Sophie A., Josephs, Tracy M., Clemens, E. Bridie, Grant, Emma J., Nguyen, Thi H. O., Wang, George C., Price, David, Miller, Adrian, Tong, Steven Y. C., Thomas, Paul G., Doherty, Peter C., Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine 2016. Molecular basis for universal HLA-A*0201 - restricted CD8+ T-cell immunity against influenza viruses. Proceedings of the National Academy of Sciences of the United States of America 113 (16) , pp. 4440-4445. 10.1073/pnas.1603106113

Du, V. Y., Bansal, A., Carlson, J., Salazar-Gonzalez, J. F., Salazar, M. G., Ladell, Kristin Ingrid, Gras, S., Josephs, T. M., Heath, S. L., Price, David, Rossjohn, Jamie, Hunter, E. and Goepfert, P. A. 2016. HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infection. The Journal of Immunology 196 (8) , pp. 3276-3286. 10.4049/jimmunol.1502411

Saunders, Philippa M., Pymm, Phillip, Pietra, Gabriella, Hughes, Victoria A., Hitchen, Corinne, O?Connor, Geraldine M., Loiacono, Fabrizio, Widjaja, Jacqueline, Price, David, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G. and Vivian, Julian P. 2016. Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition. Journal of Experimental Medicine 213 (5) , pp. 791-807. 10.1084/jem.20152023

McWilliam, Hamish E G, Eckle, Sidonia B G, Theodossis, Alex, Liu, Ligong, Chen, Zhenjun, Wubben, Jacinta M, Fairlie, David P, Strugnell, Richard A, Mintern, Justine D, McCluskey, James, Rossjohn, Jamie and Villadangos, Jose A 2016. The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1. Nature Immunology 10.1038/ni.3416

Rossjohn, Jamie and Koning, F. 2016. A biased view toward celiac disease. Mucosal Immunology 9 (3) , pp. 583-586. 10.1038/mi.2016.17

Le Nours, Jérôme, Praveena, T., Pellicci, Daniel G., Gherardin, Nicholas A., Ross, Fiona J., Lim, Ricky T., Besra, Gurdyal S., Keshipeddy, Santosh, Richardson, Stewart K., Howell, Amy R., Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie and Uldrich, Adam P. 2016. Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nature Communications 7 , 10570. 10.1038/ncomms10570

Gherardin, Nicholas A., Keller, Andrew N., Woolley, Rachel E., Le Nours, Jérôme, Ritchie, David S., Neeson, Paul J., Birkinshaw, Richard W., Eckle, Sidonia B.G., Waddington, John N., Liu, Ligong, Fairlie, David P., Uldrich, Adam P., Pellicci, Daniel G., McCluskey, James, Godfrey, Dale I. and Rossjohn, Jamie 2016. Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition. Immunity 44 (1) , p. 32. 10.1016/j.immuni.2015.12.005

Koay, Hui Fern, Gherardin, Nicholas A., Enders, Anselm, Loh, Liyen, Chen, Zhenjun, Corbett, Alexandra J., Eckle, Siodonia B. G., Meehan, Bronwyn, d’Udekem, Yves, Konstantinov, Igor, Lappas, Martha, Liu, Ligong, Goodnow, Chris C., Fairlie, David P., Rossjohn, Jamie, Kedzirska, Katherine, Berzins, Stuart P., McCluskey, James, Uldrich, Adam P., Godfrey, Dale I. and Peellicci, Daniel G. 2016. Thymic precursors to the Mucosal-Associated Invariant T cell lineage. European Journal of Immunology 46 (1) , p. 256. 10.1002/eji.201670015

Clemens, E Bridie, Grant, Emma J, Wang, Zhongfang, Gras, Stephanie, Tipping, Peta, Rossjohn, Jamie, Miller, Adrian, Tong, Steven YC and Kedzierska, Katherine 2015. Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians. Immunology and Cell Biology 94 (4) , pp. 367-377. 10.1038/icb.2015.93

Beringer, Dennis X., Kleijwegt, Fleur S., Wiede, Florian, van der Slik, Arno R., Loh, Khai Lee, Petersen, Jan, Dudek, Nadine L., Duinkerken, Gaby, Laban, Sandra, Joosten, Antoinette, Vivian, Julian P., Chen, Zhenjun, Uldrich, Adam P., Godfrey, Dale I., McCluskey, James, Price, David, Radford, Kristen J., Purcell, Anthony W., Nikolic, Tatjana, Reid, Hugh H., Tiganis, Tony, Roep, Bart O. and Rossjohn, Jamie 2015. T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex. Nature Immunology 16 (11) , pp. 1153-1161. 10.1038/ni.3271

Gartlan, K. H., Markey, K. A., Varelias, A., Bunting, M. D., Koyama, M., Kuns, R. D., Raffelt, N. C., Olver, S. D., Lineburg, K. E., Cheong, M., Teal, B. E., Lor, M., Comerford, I., Teng, M. W. L., Smyth, M. J., McCluskey, J., Rossjohn, Jamie, Stockinger, B., Boyle, G. M., Lane, S. W., Clouston, A. D., McColl, S. R., MacDonald, K. P. A. and Hill, G. R. 2015. Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects. Blood 126 (13) , pp. 1609-1620. 10.1182/blood-2015-01-622662

Saunders, Philippa M., Vivian, Julian P., O'Connor, Geraldine M., Sullivan, Lucy C., Pymm, Phillip, Rossjohn, Jamie and Brooks, Andrew G. 2015. A bird's eye view of NK cell receptor interactions with their MHC class I ligands. Immunological Reviews 267 (1) , pp. 148-166. 10.1111/imr.12319

Petersen, J., van Bergen, J., Loh, K. L., Kooy-Winkelaar, Y., Beringer, D. X., Thompson, A., Bakker, S. F., Mulder, C. J. J., Ladell, Kristin, McLaren, James Edward, Price, David, Rossjohn, Jamie, Reid, H. H. and Koning, F. 2015. Determinants of gliadin-specific T cell selection in celiac disease. The Journal of Immunology 194 (12) , pp. 6112-6122. 10.4049/jimmunol.1500161

McWilliam, Hamish EG, Birkinshaw, Richard W, Villadangos, Jose A, McCluskey, James and Rossjohn, Jamie 2015. MR1 presentation of vitamin B-based metabolite ligands. Current Opinion in Immunology 34 , pp. 28-34. 10.1016/j.coi.2014.12.004

Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, John James, Purcell, A. W., Rossjohn, Jamie, Gras, S. and Burrows, S. R. 2015. T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells. The Journal of Immunology 194 (10) , pp. 4668-4675. 10.4049/jimmunol.1500233

O'Connor, Geraldine M., Vivian, Julian P., Gostick, Emma, Pymm, Phillip, Lafont, Bernard A. P., Price, David, Rossjohn, Jamie, Brooks, Andrew G., McVicar, Daniel W. and Kirchhoff, F. 2015. Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1. Journal of Virology 89 (10) , pp. 5213-5221. 10.1128/JVI.03586-14

Magalhaes, Isabelle, Pingris, Karine, Poitou, Christine, Bessoles, Stéphanie, Venteclef, Nicolas, Kiaf, Badr, Beaudoin, Lucie, Da Silva, Jennifer, Allatif, Omran, Rossjohn, Jamie, Kjer-Nielsen, Lars, McCluskey, James, Ledoux, Séverine, Genser, Laurent, Torcivia, Adriana, Soudais, Claire, Lantz, Olivier, Boitard, Christian, Aron-Wisnewsky, Judith, Larger, Etienne, Clément, Karine and Lehuen, Agnès 2015. Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients. The Journal of Clinical Investigation 125 (4) , pp. 1752-1762. 10.1172/JCI78941

Moradi, Shoeib, Berry, Richard, Pymm, Phillip, Hitchen, Corinne, Beckham, Simone A., Wilce, Matthew C.J., Walpole, Nicholas G., Clements, Craig S., Reid, Hugh H., Perugini, Matthew A., Brooks, Andrew G., Rossjohn, Jamie and Vivian, Julian P. 2015. The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4. The Journal of Biological Chemistry 10.1074/jbc.M114.612291

Rossjohn, Jamie, Gras, Stephanie, Miles, John James, Turner, Stephen J., Godfrey, Dale I. and McCluskey, James 2015. T cell antigen receptor recognition of antigen-presenting molecules. Annual Review of Immunology 33 (1) , pp. 169-200. 10.1146/annurev-immunol-032414-112334

Birkinshaw, Richard W, Pellicci, Daniel G, Cheng, Tan-Yun, Keller, Andrew N, Sandoval-Romero, Maria, Gras, Stephanie, de Jong, Annemieke, Uldrich, Adam P, Moody, D Branch, Godfrey, Dale I and Rossjohn, Jamie 2015. αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nature Immunology 16 (3) , pp. 258-266. 10.1038/ni.3098

Miles, John James, McCluskey, James, Rossjohn, Jamie and Gras, Stephanie 2015. Understanding the complexity and malleability of T-cell recognition. Immunology and Cell Biology 93 (5) , pp. 433-441. 10.1038/icb.2014.112

Saunders, P. M., Vivian, J. P., Baschuk, N., Beddoe, T., Widjaja, J., O'Connor, G. M., Hitchen, C., Pymm, P., Andrews, D. M., Gras, S., McVicar, D. W., Rossjohn, Jamie and Brooks, A. G. 2015. The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope. The Journal of Immunology 194 (2) , pp. 781-789. 10.4049/jimmunol.1402542

Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G.D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M., Gras, Stephanie and van Veelen, Peter A. 2014. Naturally processed non-canonical HLA-A*02:01 presented peptides. The Journal of Biological Chemistry 290 (5) , pp. 2593-2603. 10.1074/jbc.M114.607028

Nivarthi, Usha K., Gras, Stephanie, Kjer-Nielsen, Lars, Berry, Richard, Lucet, Isabelle S., Miles, John J., Tracy, Samantha L., Purcell, Anthony W., Bowden, David S., Hellard, Margaret, Rossjohn, Jamie, McCluskey, James and Bharadwaj, Mandvi 2014. An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant. The Journal of Immunology 193 (11) , pp. 5402-5413. 10.4049/jimmunol.1401357

Birnbaum, Michael E., Berry, Richard, Hsiao, Yu-Shan, Chen, Zhenjun, Shingu-Vazquez, Miguel A., Yu, Xiaoling, Waghray, Deepa, Fischer, Suzanne, McCluskey, James, Rossjohn, Jamie, Walz, Thomas and Garcia, K. Christopher 2014. Molecular architecture of the αβ T cell receptor–CD3 complex. Proceedings of the National Academy of Sciences of the United States of America 111 (49) , pp. 17576-17581. 10.1073/pnas.1420936111

Fernandez, Caroline S., Amarasena, Thakshila, Kelleher, Anthony D., Rossjohn, Jamie, McClusky, James, Godfrey, Dale I. and Kent, Stephen J. 2014. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunology and Cell Biology 93 (2) , pp. 177-188. 10.1038/icb.2014.91

Trujillo, Jonathan A., Croft, Nathan P., Dudek, Nadine L., Channappanavar, Rudragouda, Theodossis, Alex, Webb, Andrew I., Dunstone, Michelle A., Illing, Patricia T., Butler, Noah S., Fett, Craig, Tscharke, David C., Rossjohn, Jamie, Perlman, Stanley and Purcell, Anthony W. 2014. The cellular redox environment alters antigen presentation. The Journal of Biological Chemistry 289 (40) , pp. 27979-91. 10.1074/jbc.M114.573402

Berry, Richard, Vivian, Julian P., Deuss, Felix A., Balaji, Gautham R., Saunders, Philipa M., Lin, Jie, Littler, Dene R., Brooks, Andrew G. and Rossjohn, Jamie 2014. The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins. The Journal of Biological Chemistry 289 (34) , pp. 23753-23763. 10.1074/jbc.M114.584128

Trujillo, Jonathan A., Gras, Stephanie, Twist, Kelly-Anne, Croft, Nathan P., Channappanavar, Rudragouda, Rossjohn, Jamie, Purcell, Anthony W. and Perlman, Stanley 2014. Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes. The Journal of Immunology 192 (11) , pp. 5245-5256. 10.4049/jimmunol.1400111

Van Rhijn, Ildiko, Gherardin, Nicholas A., Kasmar, Anne, de Jager, Wilco, Pellicci, Daniel G., Kostenko, Lyudmila, Tan, Li Lynn, Bhati, Mugdha, Gras, Stephanie, Godfrey, Dale I., Rossjohn, Jamie and Moody, D. Branch 2014. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T cell repertoire. Journal of Immunology 192 (9) , pp. 4054-4060. 10.4049/jimmunol.1400158

Petersen, Jan, Montserrat, Veronica, Mujico, Jorge R., Loh, Khai Lee, Beringer, Dennis X., van Lummel, Menno, Thompson, Allan, Mearin, M Luisa, Schweizer, Joachim, Kooy-Winkelaar, Yvonne, van Bergen, Jeroen, Drijfhout, Jan W., Kan, Wan-Ting, La Gruta, Nicole L, Anderson, Robert P., Reid, Hugh H., Koning, Frits and Rossjohn, Jamie 2014. T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease. Nature Structural and Molecular Biology 21 (5) , pp. 480-488. 10.1038/nsmb.2817

Liu, Yu Chih, Chen, Zhenjun, Neller, Michelle A., Miles, John J,, Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie and Gras, Stephanie 2014. A molecular basis for the interplay between T cells, viral mutants and human leukocyte antigen micropolymorphism. The Journal of Biological Chemistry 289 (24) , pp. 16688-98. 10.1074/jbc.M114.563502

Corbett, Alexandra J., Eckle, Sidonia B.G., Birkinshaw, Richard W., Liu, Ligong, Patel, Onisha, Mahony, Jennifer, Chen, Zhenjun, Reantragoon, Rangsima, Meehan, Bronwyn, Cao, Hanwei, Williamson, Nicholas A., Strugnell, Richard A., Van Sinderen, Douwe, Mak, Jeffrey Y.W., Fairlie, David P., Kjer-Nielsen, Lars, Rossjohn, Jamie and McCluskey, James 2014. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509 (7500) , pp. 361-365. 10.1038/nature13160

O'Connor, G. M., Vivian, J. P., Widjaja, J. M., Bridgeman, John S., Gostick, Emma, Lafont, B. A. P., Anderson, S. K., Price, David, Brooks, A. G., Rossjohn, Jamie and McVicar, D. W. 2014. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. The Journal of Immunology 192 (6) , pp. 2875-2884. 10.4049/jimmunol.1303142

Bhati, Mugdha, Cole, David, McCluskey, James, Sewell, Andrew K. and Rossjohn, Jamie 2014. The versatility of the αβ T-cell antigen receptor. Protein Science 23 (3) , pp. 260-272. 10.1002/pro.2412

Berry, Richard, Rossjohn, Jamie and Brooks, Andrew G. 2014. The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination. Immunology and Cell Biology 92 , pp. 214-220. 10.1038/icb.2013.100

Smith, Corey, Gras, Stephanie, Brennan, Rebekah M., Bird, Nicola L., Valkenburg, Sophie A., Twist, Kelly-Anne, Burrows, Jacqueline M., Miles, John James, Chambers, Daniel, Bell, Scott, Campbell, Scott, Kedzierska, Katherine, Burrows, Scott R, Rossjohn, Jamie and Khanna, Rajiv 2014. Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire. Scientific Reports 4 , 3993. 10.1038/srep03993

Stifter, Sebastian A., Gould, Jodee A., Mangan, Niamh E., Reid, Hugh H., Rossjohn, Jamie, Hertzog, Paul J. and de Weerd, Nicole A. 2014. Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells. Protein Expression and Purification 94 , pp. 7-14. 10.1016/j.pep.2013.10.019

Berry, Richard, Headey, Stephen J., Call, Melissa J., McCluskey, James, Tregaskes, Clive A., Kaufman, Jim, Koh, Ruide, Scanlon, Martin J., Call, Matthew E. and Rossjohn, Jamie 2014. Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αβT cell receptor. The Journal of Biological Chemistry 289 (12) , pp. 8240-8251. 10.1074/jbc.M113.544965

Quiñones-Parraa, Sergio, Grant, Emma, Loha, Liyen, Nguyena, Thi H. O., Campbell, Kirsty-Anne, Tong, Steven Y. C., Miller, Adrian, Doherty, Peter C., Vijaykrishnag, Dhanasekaran, Rossjohn, Jamie, Gras, Stephanie and Kedzierskaa, Katherine 2014. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proceedings of the National Academy of Sciences of the United States of America 111 (3) , pp. 1049-1054. 10.1073/pnas.1322229111

Ng, Natasha M., Littler, Dene R., Paton, Adrienne W., Le Nours, Jérôme, Rossjohn, Jamie, Paton, James C. and Beddoe, Travis 2013. EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Structure 21 (11) , pp. 2003-2013. 10.1016/j.str.2013.08.024

Scally, S., Petersen, J., Law, S., Dudek, N., Nel, H., Loh, K., Wijeyewickrema, L., Eckle, S., van Heemst, J., Pike, R., McCluskey, J., Toes, R., La Gruta, N., Purcell, A., Reid, H., Thomas, R. and Rossjohn, Jamie 2013. A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine 210 (12) , pp. 2569-2582. 10.1084/jem.20131241

Kasmar, A. G., Van Rhijn, I., Magalhaes, K. G., Young, D. C., Cheng, T.-Y., Turner, M. T., Schiefner, A., Kalathur, R. C., Wilson, I. A., Bhati, M., Gras, S., Birkinshaw, R. W., Tan, L. L., Rossjohn, Jamie, Shires, J., Jakobsen, S., Altman, J. D. and Moody, D. B. 2013. Cutting edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. The Journal of Immunology 191 (9) , pp. 4499-4503. 10.4049/jimmunol.1301660

Valkenburg, S., Quiñones-Parra, S., Gras, S., Komadina, N., McVernon, J., Wang, Z., Halim, H., Iannello, P., Cole, C., Laurie, K., Kelso, A., Rossjohn, Jamie, Doherty, P., Turner, S. and Kedzierska, K. 2013. Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides. Nature Communications 4 (3663) 10.1038/ncomms3663

Eckle, S. B., Turner, S. J., Rossjohn, Jamie and McCluskey, J. 2013. Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules? Current Opinion in Immunology 25 (5) , pp. 653-659. 10.1016/j.coi.2013.07.010

Le Nours, J., Paton, A., Byres, E., Troy, S., Herdman, B., Johnson, M., Paton, J., Rossjohn, Jamie and Beddoe, T. 2013. Structural basis of subtilase cytotoxin subAB assembly. Journal of Biological Chemistry 288 (38) , pp. 27505-27516. 10.1074/jbc.M113.462622

de Weerd, N., Vivian, J., Nguyen, T., Mangan, N., Gould, J., Braniff, S., Zaker-Tabrizi, L., Fung, K., Forster, S., Beddoe, T., Reid, H., Rossjohn, Jamie and Hertzog, P. 2013. Structural basis of a unique interferon-? signaling axis mediated via the receptor IFNAR1. Nature Immunology 14 (9) , pp. 901-907. 10.1038/ni.2667

Ng, N., Littler, D., Le Nours, J., Paton, A., Paton, J., Rossjohn, Jamie and Beddoe, T. 2013. Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB5toxin. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 69 (8) , pp. 912-915. 10.1107/S1744309113018927

Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S., Birkinshaw, R., Beddoe, T., Corbett, A., Liu, L., Miles, John James, Meehan, B., Reantragoon, R., Sandoval-Romero, M., Sullivan, L., Brooks, A., Chen, Z., Fairlie, D., McCluskey, J. and Rossjohn, Jamie 2013. Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nature Communications 4 (2142) 10.1038/ncomms3142

Van Rhijn, I., Kasmar, A., de Jong, A., Gras, S., Bhati, M., Doorenspleet, M., de Vries, N., Godfrey, D., Altman, J., de Jager, W., Rossjohn, Jamie and Moody, D. 2013. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nature Immunology 14 (7) , pp. 706-713. 10.1038/ni.2630

Rist, M. J., Theodossis, A., Croft, N. P., Neller, M. A., Welland, A., Chen, Z., Sullivan, L. C., Burrows, J. M., Miles, John James, Brennan, R. M., Gras, S., Khanna, R., Brooks, A. G., McCluskey, J., Purcell, A. W., Rossjohn, Jamie and Burrows, S. R. 2013. HLA peptide length preferences control CD8+ T cell responses. The Journal of Immunology 191 (2) , pp. 561-571. 10.4049/jimmunol.1300292

Liu, Y., Miles, John James, Neller, M., Gostick, E., Price, David, Purcell, A., McCluskey, J., Burrows, S., Rossjohn, Jamie and Gras, S. 2013. Highly divergent T-cell receptor binding modes underlie specific recognition of a bulged viral peptide bound to a human leukocyte antigen class I molecule. Journal of Biological Chemistry 288 (22) , pp. 15442-15454. 10.1074/jbc.M112.447185

Berry, R., Ng, N., Saunders, P., Vivian, J., Lin, J., Deuss, F., Corbett, A., Forbes, C., Widjaja, J., Sullivan, L., McAlister, A., Perugini, M., Call, M., Scalzo, A., Degli-Esposti, M., Coudert, J., Beddoe, T., Brooks, A. and Rossjohn, Jamie 2013. Targeting of a natural killer cell receptor family by a viral immunoevasin. Nature Immunology 14 (7) , pp. 699-705. 10.1038/ni.2605

Valkenburg, S., Gras, S., Guillonneau, C., Hatton, L., Bird, N., Twist, K., Halim, H., Jackson, D., Purcell, A., Turner, S, Doherty, P., Rossjohn, Jamie and Kedzierska, K. 2013. Preemptive priming readily overcomes structure-based mechanisms of virus escape. Proceedings of the National Academy of Sciences of the United States of America 110 (14) , pp. 5570-5575. 10.1073/pnas.1302935110

Ladell, Kristin Ingrid, Hashimoto, Masao, Iglesias, Maria Candela, Wilmann, Pascal G., McLaren, James Edward, Gras, Stéphanie, Chikata, Takayuki, Kuse, Nozomi, Fastenackels, Solène, Gostick, Emma, Bridgeman, John S., Venturi, Vanessa, Arkoub, Zaïna Aït, Agut, Henri, van Bockel, David J., Almeida, Jorge R., Douek, Daniel C., Meyer, Laurence, Venet, Alain, Takiguchi, Masafumi, Rossjohn, Jamie, Price, David and Appay, Victor 2013. A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 38 (3) , pp. 425-436. 10.1016/j.immuni.2012.11.021

Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Illing, P. T., Vivan, J. P., Rossjohn, Jamie and McCluskey, J. 2013. Human leukocyte antigen-associated drug hypersensitivity [review]. Current Opinion in Immunology 25 (1) , pp. 81-89. 10.1016/j.coi.2012.10.002

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David, Burrows, Scott R., Sewell, Andrew K. and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Eckle, Sidonia B. G., Rossjohn, Jamie and McCluskey, James 2013. Alloreactivity. In: Zachary, Andrea A. and Leffell, Mary S. eds. Transplantation Immunology, Vol. 1034. Methods in Molecular Biology, Springer, pp. 3-39. (10.1007/978-1-62703-493-7_1)

Uldrich, A., Le Nours, J., Pellicci, D., Gherardin, N., McPherson, K., Lim, R., Patel, O., Beddoe, T., Gras, S., Rossjohn, Jamie and Godfrey, D. 2013. CD1d-lipid antigen recognition by the γδTCR. Nature Immunology 14 (11) , pp. 1137-1145. 10.1038/ni.2713

Vavassori, Stefano, Kumar, Anil, Wan, Gan Siok, Ramanjaneyulu, Gundimeda S., Cavallari, Marco, El Daker, Sary, Beddoe, Travis, Theodossis, Alex, Williams, Neal K., Gostick, Emma, Price, David, Soudamini, Dinish U., Voon, Kong Kien, Olivo, Malini, Rossjohn, Jamie, Mori, Lucia and De Libero, Gennaro 2013. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nature Immunology 14 (9) , pp. 908-916. 10.1038/ni.2665

Patel, Onisha, Pellicci, Daniel G., Gras, Stephanie, Sandoval-Romero, Maria L., Uldrich, Adam P., Mallevaey, Thierry, Clarke, Andrew J., Le Nours, Jérôme, Theodossis, Alex, Cardell, Susanna L., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie 2012. Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nature Immunology 13 (9) , pp. 857-863. 10.1038/ni.2372

Bulek, Anna, Cole, David, Skowera, Ania, Dolton, Garry, Gras, Stephanie, Madura, Florian, Fuller, Anna, Miles, John, Gostick, Emma, Price, David, Drijfhout, Jan W, Knight, Robin R, Huang, Guo C, Lissin, Nikolai, Molloy, Peter E, Wooldridge, Linda, Jakobsen, Bent K, Rossjohn, Jamie, Peakman, Mark, Rizkallah, Pierre and Sewell, Andrew 2012. Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes. Nature Immunology 13 (3) , pp. 283-289. 10.1038/ni.2206

Vivian, Julian P., Duncan, Renee C., Berry, Richard, O'Connor, Geraldine M., Reid, Hugh H., Beddoe, Travis, Gras, Stephanie, Saunders, Philippa M., Olshina, Maya A., Widjaja, Jacqueline M. L., Harpur, Christopher M., Lin, Jie, Maloveste, Sebastien M., Price, David, Lafont, Bernard A. P., McVicar, Daniel W., Clements, Craig S., Brooks, Andrew G. and Rossjohn, Jamie 2011. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B [Letter]. Nature 479 (7373) , pp. 401-405. 10.1038/nature10517

Pellicci, Daniel G., Clarke, Andrew J., Patel, Onisha, Mallevaey, Thierry, Beddoe, Travis, Le Nours, Jérôme, Uldrich, Adam P., McCluskey, James, Besra, Gurdyal S., Porcelli, Steven A., Gapin, Laurent, Godfrey, Dale I. and Rossjohn, Jamie 2011. Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors. Nature Immunology 12 (9) , pp. 827-833. 10.1038/ni.2076

Iglesias, M. C., Almeida, J. R., Fastenackels, S., van Bockel, D. J., Hashimoto, M., Venturi, V., Gostick, E., Urrutia, A., Wooldridge, L., Clement, Mathew, Gras, S., Wilmann, P. G., Autran, B., Moris, A., Rossjohn, Jamie, Davenport, M. P., Takiguchi, M., Brander, C., Douek, D. C., Kelleher, A. D., Price, David and Appay, V. 2011. Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 118 (8) , pp. 2138-2149. 10.1182/blood-2011-01-328781

Pang, Siew Siew, Berry, Richard, Chen, Zhenjun, Kjer-Nielsen, Lars, Perugini, Matthew A., King, Glenn F., Wang, Christina, Chew, Sock Hui, La Gruta, Nicole L., Williams, Neal K., Beddoe, Travis, Tiganis, Tony, Cowieson, Nathan P., Godfrey, Dale I., Purcell, Anthony W., Wilce, Matthew C. J., McCluskey, James and Rossjohn, Jamie 2010. The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature 467 (7317) , pp. 844-848. 10.1038/nature09448

Beddoe, Travis, Chen, Zhenjun, Clements, Craig S., Ely, Lauren K., Bushell, Simon R., Vivian, Julian P., Kjer-Nielsen, Lars, Pang, Siew Siew, Dunstone, Michelle A., Liu, Yu Chih, Macdonald, Whitney A., Perugini, Matthew A., Wilce, Matthew C.J., Burrows, Scott R., Purcell, Anthony W., Tiganis, Tony, Bottomley, Stephen P., McCluskey, James and Rossjohn, Jamie 2009. Antigen ligation triggers a conformational change within the constant domain of the αβ T cell receptor. Immunity 30 (6) , pp. 777-788. 10.1016/j.immuni.2009.03.018