Browse by Current Cardiff authors

Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt 2019. A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical 284 , pp. 281-288. 10.1016/j.snb.2018.12.099

Mayassi, Toufic, Ladell, Kristin, Gudjonson, Herman, McLaren, James E., Shaw, Dustin G., Tran, Mai T., Rokicka, Jagoda J., Lawrence, Ian, Grenier, Jean-Christophe, van Unen, Vincent, Ciszewski, Cezary, Dimaano, Matthew, Sayegh, Hoda E., Kumar, Vinod, Wijmenga, Cisca, Green, Peter H.R., Gokhale, Ranjana, Jericho, Hilary, Semrad, Carol E., Guandalini, Stefano, Dinner, Aaron R., Kupfer, Sonia S., Reid, Hugh H., Barreiro, Luis B., Rossjohn, Jamie, Price, David A. and Jabri, Bana 2019. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Cell 176 (5) , pp. 967-981. 10.1016/j.cell.2018.12.039 Item availability restricted.

Koutsakos, Marios, Illing, Patricia T., Nguyen, Thi H. O., Mifsud, Nicole A., Crawford, Jeremy Chase, Rizzetto, Simone, Eltahla, Auda A., Clemens, E. Bridie, Sant, Sneha, Chua, Brendon Y., Wong, Chinn Yi, Allen, E. Kaitlynn, Teng, Don, Dash, Pradyot, Boyd, David F., Grzelak, Ludivine, Zeng, Weiguang, Hurt, Aeron C., Barr, Ian, Rockman, Steve, Jackson, David C., Kotsimbos, Tom C., Cheng, Allen C., Richards, Michael, Westall, Glen P., Loudovaris, Thomas, Mannering, Stuart I., Elliott, Michael, Tangye, Stuart G., Wakim, Linda M., Rossjohn, Jamie, Vijaykrishna, Dhanasekaran, Luciani, Fabio, Thomas, Paul G., Gras, Stephanie, Purcell, Anthony W. and Kedzierska, Katherine 2019. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nature Immunology , -. 10.1038/s41590-019-0320-6

Neier, Steven C., Ferrer, Alejandro, Wilton, Katelynn M., Smith, Stephen E. P., Kelcher, April M. H., Pavelko, Kevin D., Canfield, Jenna M., Davis, Tessa R., Stiles, Robert J., Chen, Zhenjun, McCluskey, James, Burrows, Scott R., Rossjohn, Jamie, Hebrink, Deanne M., Carmona, Eva M., Limper, Andrew H., Kappes, Dietmar J., Wettstein, Peter J., Johnson, Aaron J., Pease, Larry R., Daniels, Mark A., Neuhauser, Claudia, Gil, Diana and Schrum, Adam G. 2019. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology 4 (32) , eaal2201. 10.1126/sciimmunol.aal2201

Dahal-Koirala, Shiva, Ciacchi, Laura, Petersen, Jan, Risnes, Louise Fremgaard, Neumann, Ralf Stefan, Christophersen, Asbjørn, Lundin, Knut E. A., Reid, Hugh H., Qiao, Shuo-Wang, Rossjohn, Jamie and Sollid, Ludvig M. 2019. Discriminative T-cell receptor recognition of highly homologous HLA-DQ2–bound gluten epitopes. Journal of Biological Chemistry 294 (3) , pp. 941-952. 10.1074/jbc.RA118.005736

Shahine, Adam, Reinink, Peter, Reijneveld, Josephine F., Gras, Stephanie, Holzheimer, Mira, Cheng, Tan-Yun, Minnaard, Adriaan J., Altman, John D., Lenz, Steffi, Prandi, Jacques, Kubler-Kielb, Joanna, Moody, D. Branch, Rossjohn, Jamie and Van Rhijn, Ildiko 2019. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nature Communications 10 (1) , -. 10.1038/s41467-018-07898-0

Grant, Emma J., Josephs, Tracy M., Loh, Liyen, Clemens, E. Bridie, Sant, Sneha, Bharadwaj, Mandvi, Chen, Weisan, Rossjohn, Jamie, Gras, Stephanie and Kedzierska, Katherine 2018. Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans. Nature Communications 9 (1) , -. 10.1038/s41467-018-07815-5

Gherardin, Nicholas A., McCluskey, James, Rossjohn, Jamie and Godfrey, Dale I. 2018. The diverse family of MR1-restricted T cells. The Journal of Immunology 201 (10) , pp. 2862-2871. 10.4049/jimmunol.1801091

Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P. and Purcell, Anthony W. 2018. HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature Communications 9 (1) , 4693. 10.1038/s41467-018-07109-w

Balaji, Gautham R., Aguilar, Oscar A., Tanaka, Miho, Shingu-Vazquez, Miguel A., Fu, Zhihui, Gully, Benjamin S., Lanier, Lewis L., Carlyle, James R., Rossjohn, Jamie and Berry, Richard 2018. Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition. Nature Communications 9 (1) , 4623. 10.1038/s41467-018-06989-2

Faridi, Pouya, Li, Chen, Ramarathinam, Sri H., Vivian, Julian P., Illing, Patricia T., Mifsud, Nicole A., Ayala, Rochelle, Song, Jiangning, Gearing, Linden J., Hertzog, Paul J., Ternette, Nicola, Rossjohn, Jamie, Croft, Nathan P. and Purcell, Anthony W. 2018. A subset of HLA-I peptides are not genomically templated: evidence for cis- and trans-spliced peptide ligands. Science Immunology 3 (28) , eaar3947. 10.1126/sciimmunol.aar3947

Robson, Kate J., Ooi, Joshua D., Holdsworth, Stephen R., Rossjohn, Jamie and Kitching, A. Richard 2018. HLA and kidney disease: from associations to mechanisms. Nature Reviews Nephrology 14 (10) , pp. 636-655. 10.1038/s41581-018-0057-8

Wang, Huimeng, D'Souza, Criselle, Lim, Xin Yi, Kostenko, Lyudmila, Pediongco, Troi J., Eckle, Sidonia B. G., Meehan, Bronwyn S., Shi, Mai, Wang, Nancy, Li, Shihan, Liu, Ligong, Mak, Jeffrey Y. W., Fairlie, David P., Iwakura, Yoichiro, Gunnersen, Jennifer M., Stent, Andrew W., Godfrey, Dale I., Rossjohn, Jamie, Westall, Glen P., Kjer-Nielsen, Lars, Strugnell, Richard A., McCluskey, James, Corbett, Alexandra J., Hinks, Timothy S. C. and Chen, Zhenjun 2018. MAIT cells protect against pulmonary Legionella longbeachae infection. Nature Communications 9 (1) , 3350. 10.1038/s41467-018-05202-8

O'Donnell, Valerie, Rossjohn, Jamie and Wakelam, M J O 2018. Phospholipid signaling in innate immune cells. The Journal of Clinical Investigation 128 (7) , pp. 2670-2679. 10.1172/JCI97944

Awad, Wael, Le Nours, Jérôme, Kjer-Nielsen, Lars, McCluskey, James and Rossjohn, Jamie 2018. Mucosal-associated invariant T cell receptor recognition of small molecules presented by MR1. Immunology and Cell Biology 96 (6) , pp. 588-597. 10.1111/imcb.12017

Kjer-Nielsen, Lars, Corbett, Alexandra J., Chen, Zhenjun, Liu, Ligong, Mak, Jeffrey Y. W., Godfrey, Dale I., Rossjohn, Jamie, Fairlie, David P., McCluskey, James and Eckle, Sidonia B. G. 2018. An overview on the identification of MAIT cell antigens. Immunology and Cell Biology 96 (6) , pp. 573-587. 10.1111/imcb.12057

Sant, Sneha, Grzelak, Ludivine, Wang, Zhongfang, Pizzolla, Angela, Koutsakos, Marios, Crowe, Jane, Loudovaris, Thomas, Mannering, Stuart I., Westall, Glen P., Wakim, Linda M., Rossjohn, Jamie, Gras, Stephanie, Richards, Michael, Xu, Jianqing, Thomas, Paul G., Loh, Liyen, Nguyen, Thi H. O. and Kedzierska, Katherine 2018. Single-cell approach to influenza-specific CD8+ T Cell receptor repertoires across different age groups, tissues, and following influenza virus infection. Frontiers in Immunology 9 , 1453. 10.3389/fimmu.2018.01453

Rowntree, Louise C., Nguyen, Thi H. O., Halim, Hanim, Purcell, Anthony W., Rossjohn, Jamie, Gras, Stephanie, Kotsimbos, Tom C. and Mifsud, Nicole A. 2018. Inability to detect cross-reactive memory T cells challenges the frequency of heterologous immunity among common viruses. Journal of Immunology 200 (12) , pp. 3993-4003. 10.4049/jimmunol.1800010

Galperin, Moran, Farenc, Carine, Mukhopadhyay, Madhura, Jayasinghe, Dhilshan, Decroos, Amandine, Benati, Daniela, Tan, Li Lynn, Ciacchi, Lisa, Reid, Hugh H., Rossjohn, Jamie, Chakrabarti, Lisa A. and Gras, Stephanie 2018. CD4+ T cell–mediated HLA class II cross-restriction in HIV controllers. Science Immunology 3 (24) , eaat0687. 10.1126/sciimmunol.aat0687

Cotton, Rachel N, Shahine, Adam, Rossjohn, Jamie and Moody, D Branch 2018. Lipids hide or step aside for CD1-autoreactive T cell receptors. Current Opinion in Immunology 52 , pp. 93-99. 10.1016/j.coi.2018.04.013

Ramarathinam, Sri H., Gras, Stephanie, Alcantara, Sheilajen, Yeung, Amanda W.S., Mifsud, Nicole A., Sonza, Secondo, Illing, Patricia T., Glaros, Elias N., Center, Robert J., Thomas, Shane, Kent, Stephen J., Ternette, Nicola, Purcell, Damian F. J., Rossjohn, Jamie and Purcell, Anthony W. 2018. Identification of native and post-translationally modified HLA-B*57:01-restricted HIV envelope derived epitopes using immunoproteomics. PROTEOMICS 18 (12) , 1700253. 10.1002/pmic.201700253

Chennamadhavuni, Divya, Saavedra-Avila, Noemi Alejandra, Carreño, Leandro J., Guberman-Pfeffer, Matthew J., Arora, Pooja, Yongqing, Tang, Koay, Hui-Fern, Godfrey, Dale I., Keshipeddy, Santosh, Richardson, Stewart K., Sundararaj, Srinivasan, Lo, Jae Ho, Wen, Xiangshu, Gascón, José A., Yuan, Weiming, Rossjohn, Jamie, Le Nours, Jérôme, Porcelli, Steven A. and Howell, Amy R. 2018. Dual modifications of α-Galactosylceramide Synergize to promote activation of human invariant natural killer T cells and stimulate anti-tumor immunity. Cell Chemical Biology 25 (5) , pp. 571-584. 10.1016/j.chembiol.2018.02.009

Varelias, Antiopi, Bunting, Mark D., Ormerod, Kate L., Koyama, Motoko, Olver, Stuart D., Straube, Jasmin, Kuns, Rachel D., Robb, Renee J., Henden, Andrea S., Cooper, Leanne, Lachner, Nancy, Gartlan, Kate H., Lantz, Olivier, Kjer-Nielsen, Lars, Mak, Jeffrey Y.W., Fairlie, David P., Clouston, Andrew D., McCluskey, James, Rossjohn, Jamie, Lane, Steven W., Hugenholtz, Philip and Hill., Geoffrey R. 2018. Recipient mucosal-associated invariant T cells control GVHD within the colon. Journal of Clinical Investigation 128 (5) , pp. 1919-1936. 10.1172/JCI91646

Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A., Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie, Brooks, Andrew G. and Carrington, Mary 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5) , p. 1903. 10.1172/JCI98463

La Gruta, Nicole L., Gras, Stephanie, Daley, Stephen R., Thomas, Paul G. and Rossjohn, Jamie 2018. Understanding the drivers of MHC restriction of T cell receptors. Nature Reviews Immunology 10.1038/s41577-018-0007-5

Miles, John J., Tan, Mai Ping, Dolton, Garry, Edwards, Emily S. J., Galloway, Sarah A. E., Laugel, Bruno, Clement, Mathew, Makinde, Julia, Ladell, Kristin, Matthews, Katherine K., Watkins, Thomas S., Tungatt, Katie, Wong, Yide, Lee, Han Siean, Clark, Richard J., Pentier, Johanne, Attaf, Meriem, Lissina, Anya, Ager, Ann, Gallimore, Awen, Rizkallah, Pierre J., Gras, Stephanie, Rossjohn, Jamie, Burrows, Scott R., Cole, David K., Price, David A. and Sewell, Andrew K. 2018. Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. The Journal of Clinical Investigation 128 (4) , pp. 1569-1580. 10.1172/JCI91512

Godfrey, Dale I., Le Nours, Jérôme, Andrews, Daniel M., Uldrich, Adam P. and Rossjohn, Jamie 2018. Unconventional T cell targets for cancer immunotherapy. Immunity 48 (3) , pp. 453-473. 10.1016/j.immuni.2018.03.009

Chan, Kok Fei, Gully, Benjamin S., Gras, Stephanie, Beringer, Dennis X., Kjer-Nielsen, Lars, Cebon, Jonathan, McCluskey, James, Chen, Weisan and Rossjohn, Jamie 2018. Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nature Communications 9 , 1026. 10.1038/s41467-018-03321-w

Wun, Kwok S., Reijneveld, Josephine F., Cheng, Tan-Yun, Ladell, Kristin, Uldrich, Adam P., Le Nours, Jérôme, Miners, Kelly L., McLaren, James E., Grant, Emma J., Haigh, Oscar L., Watkins, Thomas S., Suliman, Sara, Iwany, Sarah, Jimenez, Judith, Calderon, Roger, Tamara, Kattya L., Leon, Segundo R., Murray, Megan B., Mayfield, Jacob A., Altman, John D., Purcell, Anthony W., Miles, John J., Godfrey, Dale I., Gras, Stephanie, Price, David A., Van Rhijn, Ildiko, Moody, D. Branch and Rossjohn, Jamie 2018. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature Immunology 19 , pp. 397-406. 10.1038/s41590-018-0065-7

Ting, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie 2018. The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. Journal of Biological Chemistry 293 (9) , pp. 3236-3251. 10.1074/jbc.RA117.001013

D'Souza, Criselle, Pediongco, Troi, Wang, Huimeng, Scheerlinck, Jean-Pierre Y., Kostenko, Lyudmila, Esterbauer, Robyn, Stent, Andrew W., Eckle, Sidonia B. G., Meehan, Bronwyn S., Strugnell, Richard A., Cao, Hanwei, Liu, Ligong, Mak, Jeffrey Y. W., Lovrecz, George, Lu, Louis, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Every, Alison L., Chen, Zhenjun and Corbett, Alexandra J. 2018. Mucosal-associated invariant T cells augment immunopathology and gastritis in chronic helicobacter pyloriInfection. The Journal of Immunology 200 (5) , pp. 1901-1916. 10.4049/jimmunol.1701512

Sundararaj, Srinivasan, Zhang, Jingjing, Krovi, S. Harsha, Bedel, Romain, Tuttle, Kathryn D., Veerapen, Natacha, Besra, Gurdyal S., Khandokar, Yogesh, Praveena, T., Le Nours, Jérôme, Matsuda, Jennifer L., Rossjohn, Jamie and Gapin, Laurent 2018. Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proceedings of the National Academy of Sciences 115 (6) , E1204-E1213. 10.1073/pnas.1716669115

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny 2018. Flow cytometric clinical immunomonitoring using peptide-MHC class II tetramers: optimization of methods and protocol development. Frontiers in Immunology 9 , 8. 10.3389/fimmu.2018.00008

Dendrou, Calliope A., Petersen, Jan, Rossjohn, Jamie and Fugger, Lars 2018. HLA variation and disease. Nature Reviews Immunology 18 , pp. 325-339. 10.1038/nri.2017.143

Sullivan, Lucy C., Walpole, Nicholas G., Farenc, Carine, Pietra, Gabriella, Sum, Matthew J. W., Clements, Craig S., Lee, Eleanor J., Beddoe, Travis, Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, Gras, Stephanie, Rossjohn, Jamie and Brooks, Andrew G. 2017. A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors. Journal of Biological Chemistry 292 (51) , pp. 21149-21158. 10.1074/jbc.M117.807719

Cook, Laura, Munier, C. Mee Ling, Seddiki, Nabila, van Bockel, David, Ontiveros, Noé, Hardy, Melinda Y., Gillies, Jana K., Levings, Megan K., Reid, Hugh H., Petersen, Jan, Rossjohn, Jamie, Anderson, Robert P., Zaunders, John J., Tye-Din, Jason A. and Kelleher, Anthony D. 2017. Circulating gluten-specific FOXP3 + CD39 + regulatory T cells have impaired suppressive function in patients with celiac disease. Journal of Allergy and Clinical Immunology 140 (6) , pp. 1592-1603. 10.1016/j.jaci.2017.02.015

Van Braeckel-Budimir, Natalija, Gras, Stephanie, Ladell, Kristin, Josephs, Tracy M., Pewe, Lecia, Urban, Stina L., Miners, Kelly, Farenc, Carine, Price, David, Rossjohn, Jamie and Harty, John T. 2017. A T cell receptor locus harbors a malaria-specific immune response gene. Immunity 47 (5) , pp. 835-847. 10.1016/j.immuni.2017.10.013

Scally, Stephen W, Law, Soi-Cheng, Ting, Yi Tian, Heemst, Jurgen van, Sokolove, Jeremy, Deutsch, Aaron J, Bridie Clemens, E, Moustakas, Antonis K, Papadopoulos, George K, Woude, Diane van der, Smolik, Irene, Hitchon, Carol A, Robinson, David B, Ferucci, Elizabeth D, Bernstein, Charles N, Meng, Xiaobo, Anaparti, Vidyanand, Huizinga, Tom, Kedzierska, Katherine, Reid, Hugh H, Raychaudhuri, Soumya, Toes, René E, Rossjohn, Jamie, El-Gabalawy, Hani and Thomas, Ranjeny 2017. Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Annals of the Rheumatic Diseases 76 (11) , pp. 1915-1923. 10.1136/annrheumdis-2017-211300

Culshaw, Abigail, Ladell, Kristin, Gras, Stephanie, McLaren, James, Miners, Kelly, Farenc, Carine, van den Heuvel, Heleen, Gostick, Emma, Dejnirattisai, Wanwisa, Wangteeraprasert, Apirath, Duangchinda, Thaneeya, Chotiyarnwong, Pojchong, Limpitikul, Wannee, Vasanawathana, Sirijitt, Malasit, Prida, Dong, Tao, Rossjohn, Jamie, Mongkolsapaya, Juthathip, Price, David and Screaton, Gavin R 2017. Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response. Nature Immunology 18 (11) , pp. 1228-1237. 10.1038/ni.3850

Mobbs, Jesse I., Illing, Patricia T., Dudek, Nadine L., Brooks, Andrew G., Baker, Daniel G., Purcell, Anthony W., Rossjohn, Jamie and Vivian, Julian P. 2017. The molecular basis for peptide repertoire selection in the human leukocyte antigen (HLA) C*06:02 molecule. Journal of Biological Chemistry 292 (42) , pp. 17203-17215. 10.1074/jbc.M117.806976

Shahine, Adam, Van Rhijn, Ildiko, Cheng, Tan-Yun, Iwany, Sarah, Gras, Stephanie, Moody, D. Branch and Rossjohn, Jamie 2017. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Science Immunology 2 (16) , eaao1384. 10.1126/sciimmunol.aao1384

Rouxel, Ophélie, Da silva, Jennifer, Beaudoin, Lucie, Nel, Isabelle, Tard, Céline, Cagninacci, Lucie, Kiaf, Badr, Oshima, Masaya, Diedisheim, Marc, Salou, Marion, Corbett, Alexandra, Rossjohn, Jamie, McCluskey, James, Scharfmann, Raphael, Battaglia, Manuela, Polak, Michel, Lantz, Olivier, Beltrand, Jacques and Lehuen, Agnès 2017. Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes. Nature Immunology 18 (12) , pp. 1321-1331. 10.1038/ni.3854

Brennan, Patrick J., Cheng, Tan-Yun, Pellicci, Daniel G., Watts, Gerald F. M., Veerapen, Natacha, Young, David C., Rossjohn, Jamie, Besra, Gurdyal S., Godfrey, Dale I., Brenner, Michael B. and Moody, D. Branch 2017. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proceedings of the National Academy of Sciences of the United States of America 114 (31) , pp. 8348-8353. 10.1073/pnas.1705882114

Littler, Dene R., Ang, Sheng Y., Moriel, Danilo G., Kocan, Martina, Kleifeld, Oded, Johnson, Matthew D., Tran, Mai T., Paton, Adrienne W., Paton, James C., Summers, Roger J., Schembri, Mark A., Rossjohn, Jamie and Beddoe, Travis 2017. Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins. Journal of Biological Chemistry 292 (36) , pp. 15143-15158. 10.1074/jbc.M117.796094

Deuss, Felix A., Gully, Benjamin S., Rossjohn, Jamie and Berry, Richard 2017. Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT). Journal of Biological Chemistry 292 (27) , pp. 11413-11422. 10.1074/jbc.M117.786483

Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I., Vivian, Julian P., Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E., Dendrou, Calliope A., Carrington, Mary, McVean, Gil, Purcell, Anthony W., Rossjohn, Jamie and Fugger, Lars 2017. Structural and regulatory diversity shape HLA-C protein expression levels. Nature Communications 8 , p. 15924. 10.1038/ncomms15924

Shaler, Christopher R., Choi, Joshua, Rudak, Patrick T., Memarnejadian, Arash, Szabo, Peter A., Tun-Abraham, Mauro E., Rossjohn, Jamie, Corbett, Alexandra J., McCluskey, James, McCormick, John K., Lantz, Olivier, Hernandez-Alejandro, Roberto and Haeryfar, S.M. Mansour 2017. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLoS Biology 15 (6) , e2001930. 10.1371/journal.pbio.2001930

Ooi, Joshua D., Petersen, Jan, Tan, Yu H., Huynh, Megan, Willett, Zoe J., Ramarathinam, Sri H., Eggenhuizen, Peter J., Loh, Khai L., Watson, Katherine A., Gan, Poh Y., Alikhan, Maliha A., Dudek, Nadine L., Handel, Andreas, Hudson, Billy G., Fugger, Lars, Power, David A., Holt, Stephen G., Coates, P. Toby, Gregersen, Jon W., Purcell, Anthony W., Holdsworth, Stephen R., La Gruta, Nicole L., Reid, Hugh H., Rossjohn, Jamie and Kitching, A. Richard 2017. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature 545 (7653) , pp. 243-247. 10.1038/nature22329

De Weerd, Nicola A., Matthews, Anthony Y., Pattie, Philip R., Bourke, Nollaig M., Lim, San S., Vivian, Julian P., Rossjohn, Jamie and Hertzog, Paul J. 2017. A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling. World Journal of Biological Chemistry 10.1074/jbc.M116.773788

Keller, Andrew N., Eckle, Sidonia B. G., Xu, Weijun, Liu, Ligong, Hughes, Victoria A., Mak, Jeffrey Y. W., Meehan, Bronwyn S., Pediongco, Troi, Birkinshaw, Richard W., Chen, Zhenjun, Wang, Huimeng, D'Souza, Criselle, Kjer-Nielsen, Lars, Gherardin, Nicholas A., Godfrey, Dale I., Kostenko, Lyudmila, Corbett, Alexandra J., Purcell, Anthony W., Fairlie, David P., McCluskey, James and Rossjohn, Jamie 2017. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nature Immunology 18 (4) , pp. 402-411. 10.1038/ni.3679

Pymm, Phillip, Illing, Patricia T, Ramarathinam, Sri H, O'Connor, Geraldine M, Hughes, Victoria A, Hitchen, Corinne, Price, David, Ho, Bosco K, McVicar, Daniel W, Brooks, Andrew G, Purcell, Anthony W, Rossjohn, Jamie and Vivian, Julian P 2017. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nature Structural & Molecular Biology 24 (4) , pp. 387-394. 10.1038/nsmb.3381

Aguilar, Oscar A., Berry, Richard, Rahim, Mir Munir A., Reichel, Johanna J., Popović, Branka, Tanaka, Miho, Fu, Zhihui, Balaji, Gautham R., Lau, Timothy N.H., Tu, Megan M., Kirkham, Christina L., Mahmoud, Ahmad Bakur, Mesci, Aruz, Krmpotić, Astrid, Allan, David S.J., Makrigiannis, Andrew P., Jonjić, Stipan, Rossjohn, Jamie and Carlyle, James R. 2017. A viral immunoevasin controls innate immunity by targeting the prototypical natural killer cell receptor family. Cell 169 (1) , pp. 58-71. 10.1016/j.cell.2017.03.002

Mak, Jeffrey Y. W., Xu, Weijun, Reid, Robert C., Corbett, Alexandra J., Meehan, Bronwyn S., Wang, Huimeng, Chen, Zhenjun, Rossjohn, Jamie, McCluskey, James, Liu, Ligong and Fairlie, David P. 2017. Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells. Nature Communications 8 , 14599. 10.1038/ncomms14599

Cheng, Janice M. H., Liu, Ligong, Pellicci, Daniel G., Reddiex, Scott J. J., Cotton, Rachel N., Cheng, Tan-Yun, Young, David C., Van Rhijn, Ildiko, Moody, D. Branch, Rossjohn, Jamie, Fairlie, David P., Godfrey, Dale I. and Williams, Spencer J. 2017. Total synthesis of Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition. Chemistry - A European Journal 23 (7) , pp. 1694-1701. 10.1002/chem.201605287

Chen, Z., Wang, H., D'Souza, C., Sun, S., Kostenko, L., Eckle, S. B. G., Meehan, B. S., Jackson, D. C., Strugnell, R. A., Cao, H., Wang, N., Fairlie, D. P., Liu, L., Godfrey, D. I., Rossjohn, Jamie, McCluskey, J. and Corbett, A. J. 2017. Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals. Mucosal Immunology 10 (1) , pp. 58-68. 10.1038/mi.2016.39 Item availability restricted.

Grant, Emma J., Josephs, Tracy M., Valkenburg, Sophie A., Wooldridge, Linda, Hellard, Margaret, Rossjohn, Jamie, Bharadwaj, Mandvi, Kedzierska, Katherine and Gras, Stephanie 2016. Lack of heterologous cross-reactivity toward HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures. Journal of Biological Chemistry 291 (47) , pp. 24335-24351. 10.1074/jbc.M116.753988

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De Weerd, N. A., Matthews, A., Lim, S. S., Pattie, P., Bourke, N., Vivian, J. P., Rossjohn, Jamie and Hertzog, P. J. 2016. P140: Understanding the IFNÂ-IFNAR1 interface: implications for drug discovery in IFNÂ-DRIVEN disease [Poster Abstract]. Cytokine 87 , p. 120. 10.1016/j.cyto.2016.07.021

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Gras, Stephanie, Chadderton, Jesseka, Del Campo, Claudia M., Farenc, Carine, Wiede, Florian, Josephs, Tracy M., Sng, Xavier Y. X., Mirams, Michiko, Watson, Katherine A., Tiganis, Tony, Quinn, Kylie M., Rossjohn, Jamie and La Gruta, Nicole L. 2016. Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response. Immunity 45 (4) , pp. 749-760. 10.1016/j.immuni.2016.09.007

Littler, Dene R., Bullen, Hayley E., Harvey, Katherine L., Beddoe, Travis, Crabb, Brendan S., Rossjohn, Jamie and Gilson, Paul R. 2016. Disrupting the allosteric interaction between the plasmodium falciparumcAMP-dependent kinase and its regulatory subunit. Journal of Biological Chemistry 291 (49) , p. 25375. 10.1074/jbc.M116.750174

Petersen, Jan, Kooy-Winkelaar, Yvonne, Loh, Khai Lee, Tran, Mai, van Bergen, Jeroen, Koning, Frits, Rossjohn, Jamie and Reid, Hugh H. 2016. Diverse T cell receptor gene usage in HLA-DQ8-associated celiac disease converges into a consensus binding solution. Structure 24 (10) , pp. 1643-1657. 10.1016/j.str.2016.07.010

Kim, Ji Hyung, Hu, Yu, Yongqing, Tang, Kim, Jessica, Hughes, Victoria A., Le Nours, Jerome, Marquez, Elsa A., Purcell, Anthony W., Wan, Qi, Sugita, Masahiko, Rossjohn, Jamie and Winau, Florian 2016. CD1a on Langerhans cells controls inflammatory skin disease. Nature Immunology 17 (10) , pp. 1159-1166. 10.1038/ni.3523

Pageon, Sophie V., Tabarin, Thibault, Yamamoto, Yui, Ma, Yuanqing, Bridgeman, John S, Cohnen, André, Benzing, Carola, Gao, Yijun, Crowther, Michael D, Tungatt, Katie, Dolton, Garry, Sewell, Andrew, Price, David A, Acuto, Oreste, Parton, Robert G., Gooding, J. Justin, Rossy, Jérémie, Rossjohn, Jamie and Gaus, Katharina 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proceedings of the National Academy of Sciences 113 (37) , E5454-E5463. 10.1073/pnas.1607436113

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Vinton, Carol, Wu, Fan, Rossjohn, Jamie, Matsuda, Kenta, McCluskey, James, Hirsch, Vanessa, Price, David, Brenchley, Jason M. and Silvestri, G. 2016. Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques. Journal of Virology 90 (9) , pp. 4520-4529. 10.1128/JVI.02876-15

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Jaafar, Nardiah Rizwana, Littler, Dene, Beddoe, Travis, Rossjohn, Jamie, Illias, Rosli Md, Mahadi, Nor Muhammad, Mackeen, Mukram Mohamed, Murad, Abdul Munir Abdul and Abu Bakar, Farah Diba 2016. Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeastGlaciozyma antarctica PI12. Acta Crystallographica Section F Structural Biology Communications 72 (11) , pp. 831-839. 10.1107/S2053230X16015612

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Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G.D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M., Gras, Stephanie and van Veelen, Peter A. 2014. Naturally processed non-canonical HLA-A*02:01 presented peptides. The Journal of Biological Chemistry 290 (5) , pp. 2593-2603. 10.1074/jbc.M114.607028

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Fernandez, Caroline S., Amarasena, Thakshila, Kelleher, Anthony D., Rossjohn, Jamie, McClusky, James, Godfrey, Dale I. and Kent, Stephen J. 2014. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunology and Cell Biology 93 (2) , pp. 177-188. 10.1038/icb.2014.91

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Berry, Richard, Vivian, Julian P., Deuss, Felix A., Balaji, Gautham R., Saunders, Philipa M., Lin, Jie, Littler, Dene R., Brooks, Andrew G. and Rossjohn, Jamie 2014. The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins. The Journal of Biological Chemistry 289 (34) , pp. 23753-23763. 10.1074/jbc.M114.584128

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Liu, Yu Chih, Chen, Zhenjun, Neller, Michelle A., Miles, John J,, Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie and Gras, Stephanie 2014. A molecular basis for the interplay between T cells, viral mutants and human leukocyte antigen micropolymorphism. The Journal of Biological Chemistry 289 (24) , pp. 16688-98. 10.1074/jbc.M114.563502

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Bhati, Mugdha, Cole, David, McCluskey, James, Sewell, Andrew K. and Rossjohn, Jamie 2014. The versatility of the αβ T-cell antigen receptor. Protein Science 23 (3) , pp. 260-272. 10.1002/pro.2412

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Stifter, Sebastian A., Gould, Jodee A., Mangan, Niamh E., Reid, Hugh H., Rossjohn, Jamie, Hertzog, Paul J. and de Weerd, Nicole A. 2014. Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells. Protein Expression and Purification 94 , pp. 7-14. 10.1016/j.pep.2013.10.019

Berry, Richard, Headey, Stephen J., Call, Melissa J., McCluskey, James, Tregaskes, Clive A., Kaufman, Jim, Koh, Ruide, Scanlon, Martin J., Call, Matthew E. and Rossjohn, Jamie 2014. Structure of the chicken CD3εδ/γ heterodimer and its assembly with the αβT cell receptor. The Journal of Biological Chemistry 289 (12) , pp. 8240-8251. 10.1074/jbc.M113.544965

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Ng, Natasha M., Littler, Dene R., Paton, Adrienne W., Le Nours, Jérôme, Rossjohn, Jamie, Paton, James C. and Beddoe, Travis 2013. EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit. Structure 21 (11) , pp. 2003-2013. 10.1016/j.str.2013.08.024

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