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Number of items: 24.

Pertusati, Fabrizio, Ferla, Salvatore, Bassetto, Marcella, Brancale, Andrea, Kandil, Sahar, Westwell, Andrew D. and McGuigan, Christopher 2019. A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer. European Journal of Medicinal Chemistry 180 , pp. 1-14. 10.1016/j.ejmech.2019.07.001
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Morozzi, Chiara, Sedláková, Jana, Serpi, Michaela, Avigliano, Marialuce, Carbajo, Rosangela, Sandoval, Lucia, Valles-Ayoub, Yadira, Crutcher, Patrick, Thomas, Stephen and Pertusati, Fabrizio 2019. Targeting GNE myopathy: A dual prodrug approach for the delivery of N-acetylmannosamine 6-phosphate. Journal of Medicinal Chemistry , -. 10.1021/acs.jmedchem.9b00833
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Pileggi, Elisa, Serpi, Michaela and Pertusati, Fabrizio 2018. Preparation of pyrimidine alkenyl acyclic nucleoside phosphonoamidates. Current Protocols in Nucleic Acid Chemistry 74 (13-14) , e56. 10.1002/cpnc.56
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Pileggi, Elisa, Serpi, Michaela, Andrei, Graciela, Schols, Dominique, Snoeck, Robert and Pertusati, Fabrizio 2018. Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs. Bioorganic and Medicinal Chemistry 26 (12) , pp. 3596-3609. 10.1016/j.bmc.2018.05.034
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Slusarczyk, Magdalena, Serpi, Michaela and Pertusati, Fabrizio 2018. Phosphoramidates and phosphonamidates (ProTides) with antiviral activity. Antiviral Chemistry and Chemotherapy 26 , pp. 1-31. 10.1177/2040206618775243
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Pertusati, Fabrizio, Serafini, Sara, Albadry, Najmiyah, Snoeck, Robert and Andrei, Graciela 2017. Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy. Antiviral Research 143 , pp. 262-268. 10.1016/j.antiviral.2017.04.013
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Serpi, Michaela, De Biasi, Roberto, Pertusati, Fabrizio, Slusarczyk, Magdalena and McGuigan, Christopher 2017. Synthetic approaches for the preparation of phosphoramidate prodrugs of 2’-deoxypseudoisocytidine. ChemistryOpen 6 (3) , pp. 424-436. 10.1002/open.201700019
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Bassetto, Marcella, Ferla, Salvatore, Giancotti, Gilda, Pertusati, Fabrizio, Westwell, Andrew D., Brancale, Andrea and McGuigan, Christopher 2017. Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents. MedChemComm 8 (7) , pp. 1414-1420. 10.1039/C7MD00164A
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James, Edward, Pertusati, Fabrizio, Brancale, Andrea and McGuigan, Christopher 2017. Kinase-independent phosphoramidate S1P1 receptor agonist benzyl ether derivatives. Biorganic and Medicinal Chemistry Letters 27 (6) , pp. 1371-1378. 10.1016/j.bmcl.2017.02.011
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Pertusati, Fabrizio, Nutz, Eva, Kariuki, Benson and Coogan, Michael P. 2017. Synthesis and substrate-controlled reactions of 2,2′-unsaturated biquinazolinones. Tetrahedron 73 (1) , pp. 55-63. 10.1016/j.tet.2016.11.060
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Marinozzi, Maura, Pertusati, Fabrizio and Serpi, Michaela 2016. λ5-Phosphorus-Containing α-Diazo Compounds (PCDCs): a valuable tool for accessing phosphorus-functionalized molecules. Chemical Reviews 116 (22) , pp. 13991-14055. 10.1021/acs.chemrev.6b00373
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Serpi, Michaela, Ferrari, Valentina and Pertusati, Fabrizio 2016. Nucleosided derived antibiotics to fight microbial drug resistance: New utilities for an established class of drugs? Journal of Medicinal Chemistry 59 (23) , pp. 10343-10382. 10.1021/acs.jmedchem.6b00325
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Bassetto, Marcella, Ferla, Salvatore, Pertusati, Fabrizio, Kandil, Sahar, Westwell, Andrew, Brancale, Andrea and McGuigan, Christopher 2016. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer. European Journal of Medicinal Chemistry 118 , pp. 230-243. 10.1016/j.ejmech.2016.04.052
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Ferla, Salvatore, Bassetto, Marcella, Pertusati, Fabrizio, Kandil, Sahar, Westwell, Andrew David, Brancale, Andrea and McGuigan, Christopher 2016. Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety. Bioorganic & Medicinal Chemistry Letters 26 (15) , pp. 3636-3640. 10.1016/j.bmcl.2016.06.001
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McGuigan, Christopher, Serpi, Michaela, Slusarczyk, Magdalena, Ferrari, Valentina, Pertusati, Fabrizio, Meneghesso, Silvia, Derudas, Marco, Farleigh, Laura, Zanetta, Paola and Bugert, Joachim Jakob 2016. Anti-flavivirus activity of different tritylated pyrimidine and purine nucleoside analogues. ChemistryOpen 5 (3) , pp. 227-235. 10.1002/open.201500216
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Pertusati, Fabrizio and McGuigan, Christopher 2015. Diastereoselective synthesis of P-chirogenic phosphoramidate prodrugs of nucleoside analogues (ProTides) via copper catalysed reaction. Chemical Communications 51 (38) , pp. 8070-8073. 10.1039/C5CC00448A
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Pertusati, Fabrizio, McGuigan, Christopher and Serpi, Michaela 2015. Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery. Current Protocols in Nucleic Acid Chemistry, Wiley-Blackwell, 60:15.6.1-15.6.10. (10.1002/0471142700.nc1506s60)
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Ferrari, Valentina, Serpi, Michaela, McGuigan, Christopher and Pertusati, Fabrizio 2015. Chemoselective N-deacetylation of protected nucleosides and nucleotides promoted by the Schwartz's reagent. Nucleosides, Nucleotides & Nucleic Acids 34 (11) , pp. 799-814. 10.1080/15257770.2015.1075552
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Toti, Kiran S., Derudas, Marco, Pertusati, Fabrizio, Sinnaeve, Davy, Van den Broeck, Freya, Margamuljana, Lia, Martins, José C., Herdewijn, Piet, Balzarini, Jan, McGuigan, Christopher and Van Calenbergh, Serge 2014. Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity. Journal of Organic Chemistry 79 (11) , pp. 5097-5112. 10.1021/jo500659e
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Pertusati, Fabrizio, Hinsinger, Karen, Flynn, Áine Sinéad, Powell, Ned George, Tristram, Amanda Jane, Balzarini, Jan and McGuigan, Christopher 2014. PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer. European Journal of Medicinal Chemistry 78 , pp. 259-268. 10.1016/j.ejmech.2014.03.051
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McGuigan, Christopher, Derudas, Marco, Gonczy, Blanka, Hinsinger, Karen, Kandil, Sahar, Pertusati, Fabrizio, Serpi, Michaela, Snoeck, Robert, Andrei, Graciela, Balzarini, Jan, McHugh, Timothy D., Maitra, Arundhati, Akorli, Ernest, Evangelopoulos, Dimitrios and Bhakta, Sanjib 2014. ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents. Bioorganic & Medicinal Chemistry 22 (9) , pp. 2816-2824. 10.1016/j.bmc.2014.02.056
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McGuigan, Christopher, Bourdin, Claire, Derudas, Marco, Hamon, Nadege, Hinsinger, Karen, Kandil, Sahar, Madela, Karolina, Meneghesso, Silvia, Pertusati, Fabrizio, Serpi, Michaela, Slusarczyk, Magdalena, Chamberlain, Stanley, Kolykhalov, Alexander, Vernachio, John, Vanpouille, Christophe, Introini, Andrea, Margolis, Leonid and Balzarini, Jan 2013. Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides. European Journal of Medicinal Chemistry 70 , pp. 326-340. 10.1016/j.ejmech.2013.09.047
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Pertusati, Fabrizio, Serpi, Michaela and McGuigan, Christopher 2011. Medicinal chemistry of nucleoside phosphonate prodrugs for antiviral therapy. Antiviral Chemistry and Chemotherapy 22 (5) , pp. 181-203. 10.3851/IMP2012
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Pertusati, Fabrizio 2007. Synthesis of atropisomeric 2,2'-disubstituted-3,3'-quinazolin-4,4'-diones and their application in asymmetric synthesis. PhD Thesis, Cardiff University.
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This list was generated on Fri Dec 6 05:13:47 2019 GMT.